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열처리에 의한 Casein Micelle 의 성질변화에 관한 연구
김세헌,김영교 ( S . H . Kim,Y . K . Kim ) 한국축산학회 1986 한국축산학회지 Vol.28 No.10
This experiment was conducted to study the changes of physico-chemical properties and their contents of casein micelles by heat treatment at various temperatures and times. Fresh or heated casein micelles were fractionated into different sizes by various ultra-centrifugation times and the relative amount of protein of each fraction to the total protein was determined. Some properties of these fractions were also tested by rennet action. Heat-induced changes of casein micelles were observed by polyacrylamide gel electrophoresis. The results were summarized as follows; 1. When skimmilk was ultracentrifuged at 100,000xg for 60 minutes, the proportions of the casein micelles sedimented, serum casein and whey protein to the total protein were 69.97%, 9.86% and 20.47%, respectively. By the heat treatment at 95℃ for 10 minutes, the proportions of these fractions to the total protein were changed to 76.13%o, 20.31% and 3.56%, respectively. 2. When skimmilk was ultracentrifuged at 100,000xg for 10, 30 and 60 minutes, the proportions of pellet 1, 2, 3 and serum casein to the total casein were 27.17%, 45.52%, 14.91% and 12.40%, respectively. In case of heat treatment at 95℃ for 10 minutes, the proportions of these fractions to the total casein were changed to 17.42%, 28.64%, 32.88% and 21.06%, respectively. 3. Non-protein nitrogen soluble in 12% TCA released from ultra-centrifugal serum casein (100,000xg, 60 min) by rennet action was decreased with increase of heating time and temperature. 4. As the results of gel electrophoresis, a new band appeared between α_s-casein and β-casein and its density was increased gradually with the heat treatment at 75℃ or higher temperature.
Strain-Polarization Coupling Manifested by Impedance Spectroscopy
김세헌,이철의,D. H. Kim,장동영,J. H. Han,이규원,이광세 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.48 No.3
The ferroelastic phase in hydrogen-bonded TlH2PO4 was investigated by means of impedance spectroscopy. The temperature-dependent dielectric susceptibility exhibited perfect agreement with that expected for strain-polarization coupling. The high-temperature dielectric susceptibility revealed the corresponding Curie-Weiss temperature to be far above the antiferroelectric phase transition temperature, indicative of a novel mixed phase between the antiferroelectric and the ferroelastic phase transitions.3Hb
분석적-종합적 사고 양식이 고의성 판단에 미치는 영향: 범죄 전형성의 역할
김세헌,허태균,최승혁,Seheon Kim,Taekyun Hur,Seung-Hyuk Choi 한국문화및사회문제심리학회 2023 한국심리학회지: 문화 및 사회문제 Vol.29 No.2
This study was conducted to determine how analytic-holistic thinking style, one of the cultural characteristics, affects intentionality judgment and what role the crime typicality plays in the process. To this end, the psychological mechanism of intentionality judgment was confirmed in cases where the criminal typicality was manipulated by the moral characteristics of the crime perpetrator and victim. As a result, higher the criminal typicality lead to higher intentionality judgement. In addition, it was found that people with relatively holistic thinking style (with high causality and perception of change) judge less of the perpetrator intentionality. In particular, it was confirmed that the analytic-holistic thinking style interacts with criminal typicality and affects the intentionality judgment. Specifically, people with a holistic thinking style (high causality) judged the perpetrator to have high intentionality in typical cases, but judged in a reverse way in atypical cases. It means that, holistic thinkers, compared to analytic thinkers, strongly judge intentionality based on criminal typicality considering the moral characteristics of not only the perpetrators but also the victims. Along with the significance of this study, the relationships among analytic-holistic thinking style, criminal typicality and intentionality judgment were discussed.
김세헌(Se-Heon Kim),김영훈(Young Hoon Kim),김현수(Hyun Soo Kim),조창일(Chang Il Cho),김유석(Yu Seok Kim),박영민(Young Min Park) 대한두경부종양학회 2007 대한두경부 종양학회지 Vol.23 No.2
Introduction :Sarcoma of the head and neck region is a very rare disease entity. This retrospective study investigated the clinical characteristics of head and neck sarcomas and analyzed its treatment methods and outcomes. Subjects and Methods :Eighty-five patients who were diagnosed as sarcomas of the head and neck region in Shinchon Severance Hospital between 1985 and 2005 were included in the study. Data concerning age, sex, symp-toms, location and size of tumor, histopathologic characteristics, treatment methods, recurrence, and distant me-tastasis were reviewed. Result :Overall 5 year survival rate was 38% and the 5 year survival rate in the pediatric population was 60%. The 5 year survival rates for each osteosarcoma and soft tissue sarcoma cases were 42% and 37% res-pectively. The 5 year survival rate was significantly higher in the cases where complete surgical resection was achieved. Conclusion :In managing head and neck sarcomas, it is important to perform wide resection and to achieve complete resection.
Matrix Metalloproteinases(MMPs) 및 Vascular Endothelial Growth Factor(VEGF)의 발현을 통한 구강 설암의 침윤 기전 연구
김세헌(Se Heon Kim),김지훈(Ji Hoon Kim),임재열(Jae Yul Lim),조남훈(Nam Hoon Cho),장정현(Jung Hyun Chang),최은창(Eun Chang Choi),김정홍(Jeong Hong Kim) 대한두경부종양학회 2005 대한두경부 종양학회지 Vol.21 No.1
Purpose: In oral tongue cancer, the degree of tumor invasion has a significant effect on the prognosis. We hypothesized that the destruction of extracelluar matrix and neovascularization are related to tumor infiltration mechanism. By studying the the tissues of early stage oral tongue cancer patients, we are intend to clarify the invasion related factors in oral tongue cancer. Material and Methods: To demonstrate the invasion process in early T-stage oral tongue cancer, the expressions of extracellular matrix destruction related molecules(MMP2, MMP9) and neovascularization related molecule(VEGF) were observed by immunohistochemical study. Also, immunohistochemical staining of CD31 was done for quantification of neovascularization. With the experiment showed above, we analyzed relationship between expression of each substances and tumor invasion depth, tumor free survival rates and cervical lymph node metastasis rate in early T-stage oral tongue cancer. Results: The expression rates of MMP2, MMP9, VEGF in 38 early oral cancer patients were 52.6%, 78.9% 52.6%, respectively. Significant correlation was found between the VEGF expression and microvessel density showed by CD31 immunohistochemical staining(p