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메밀 지상부의 DPPH 라디칼 소거작용과 활성 플라보노이드의 분리
김성자,김현주,박종철,Kim Sung-Ja,Kim Hyun-Joo,Park Jong-Cheol 대한한의학방제학회 2004 大韓韓醫學方劑學會誌 Vol.12 No.1
The inhibitory effect of the aerial parts of Fagopyrum esculentum on the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical was examined. The n-butanol fraction from the methanol extract of title plant showed stronger inhibitory effect than other fractions on DPPH radical. Two flavonoids were isolated from n-butanol fraction having the potent activity and elucidated as quercetin-3-O-${\alpha}$-L-rhamnoside and quercetin-3-O-rutinoside on the basis of spectral evidence. The $IC_{50}$ values of these compounds on DPPH radical were 6.56 ${\mu}M$ and 8.37 ${\mu}M$, respectively.
위암 및 위암의 전구 병변에서 p16INK4A 촉진자의 과메칠화
김남일 ( Nam Il Kim ),김대인 ( Dae In Kim ),김성자 ( Sung Ja Kim ),이구 ( Goo Lee ),서정일 ( Jung Il Suh ),이창우 ( Chang Woo Lee ),장태정 ( Tae Jung Jang ),김한식 ( Han Sik Kim ),이규춘 ( Kyu Chun Lee ),최명규 ( Myung Gyu Choi ) 대한소화기학회 2002 대한소화기학회 춘계학술대회 Vol.2002 No.-
<목적> 위암에서 p16INK4A 유전자의 불활성화는 p16INK4A 촉진자의 과메칠화에 의한 불활성화가 중요한 기전으로 보고되었지만 현재까지 위암 주변 조직의 p16INK4A 촉진자의 과메칠화와 위암의 전구 병변에 대한 연구는 없는 실정이다. 따라서 본 연구는 만성위염, 위선종, 위암과 위암에 인접한 비종양성 조직에서 p16INK4A 촉진자의 메칠화를 조사하고 p16INK4A 단백질의 발현을 분석하여 위암의 다단계 발생에서 p16INK4A 촉진자 과메
김성자(Kim Sung-Ja),이중희(Lee Jung-Hee) 국제지역연구학회 2014 국제지역학논총 Vol.7 No.1
베이징시는 주민의 소득수준 향상으로 인해 문화소비에 대한 욕구가 증가하고 있는데, 소득수준이 문화소비에 있어서 결정적인 요인으로 작용하기 때문에 소득계층별 문화소비의 격차가 존재한다. 고소득계층일수록 문화소비 중 해외여행소비가 급증하고 있는데 중국정부의 아웃바운드 관광정책발전, 주 5일 근무제 도입과 유급휴가제에 따른 여가시간 확대는 소득수준 향상과 맞물려 베이징시 주민의 해외여행소비 증가의 중요한 요인으로 작용하였다. 또한 인터넷 보급률 증가로 전자상거래가 용이해지면서 온라인 여행사가 급증하였고, 이는 온라인 여행상품 구매증가로 확대되었다. 최근 중국은 여유법 시행으로 인해 향후 단체여행 보다는 개인자유여행위주로, 저가의 여행상품 보다는 고가이지만 고급여행상품 위주로의 소비가 이루어 질 것이다. 그리고 베이징시는 해외여행을 포함하고 있는 문화소비에 있어서 소득계층별로 격차를 보이므로 우리나라 관련업계의 중국관광객 유치에 있어서 소비자들의 소비행태를 정확히 파악하여 소득계층별 유치 전략을 달리 하여야 할 것이다. 또한, 중국인들의 소득수준 향상으로 인해 질적인 소비수요가 증가하면서 소비자들의 니즈(needs)를 정확히 파악하여 여행상품개발의 다양화를 모색하여야 할 것이다. Since China reformed and opened its economy in 1978, the average economic growth rate has been 10 percent, and chinese" income level has increased rapidly. The advancement of outbound tourism by Chinese government and increase in leisure time by the introduction of the five-day work week and the paid vacation, with a rise in the income level, have become a huge factor in the growth of Beijing citizens" spending on their overseas trip. Also, the number of online travel agencies increased sharply as internet trade became easy to use due to the growth in supply of internet, which lead to increase in online purchasing travel packages. The number of outbound tourists increased 22.7 times from 12,000 in 1995 to 2,725,000 in 2012. Besides, the demand on cultural consumption has been increasing due to improvement in their academic abilities and income levels in Beijing. However, there are gaps in cultural consumption among income classes. Recently, the middle and upper classes" spending on cultural consumption(service expenses on culture and entertainment) is the highest whereas the lower classes" educational expenses are still the highest. It is expected that chinese will prefer personal travel to group tours and spend more money on high priced tours than low priced things thanks to tourism promotion act that Chinese government lately implemented. There are gaps in cultural consumption among regions and income classes in Beijing. So we need to make sure to figure out the consumption pattern and vary marketing strategies according to income classes in order to attract the tourists to Korea. In addition, as qualitative consumption demand increases owing to improvement in chinese income levels, we need to find out consumer needs and diversify travel packages.
중학교 '역사' 교육과정 및 교과서에서 '교육내용 적정화' 담론의 수용과 굴절
金成子(Kim Sung-Ja) 歷史敎育硏究會 2012 역사교육 Vol.121 No.-
Whenever National curriculum was revised, it has been raised that the burden of student learning should be eased through lowering the difficulty and amount of educational content, the discourse about 'reduction of educational content'. The research team of developing general guidelines tried to solve the problem through reducing the number of semester course taken and the content of subject matter of National curriculum. The development team of History National Curriculum accepted the demands of the research team about reducing educational content by way of 'reduced number of achievement standards. This was possible by parallel integration of achievement standards and slimming the form of documents in the History National Curriculum. However, it was hard to approve that amount of learning or educational content is substantially reduced through integration. In the analysis about textbooks developed according to 2010 History National Curriculum, despite slimming the form of documents in the History National Curriculum, it was hard to believe that 'reduction of educational content' was accomplished. Thus, the discourse about 'reduction of educational content', intended by general guideline which is the upper stage in the development work of national curriculum, was not implemented in the sub-step, History National Curriculum and history textbooks.
종양병동 간호사의 공감피로 및 공감만족에 따른 우울, 불안, 수면장애
김성자(Kim, Sung Ja),나현주(Na, Hyunjoo) 대한종양간호학회 2017 Asian Oncology Nursing Vol.17 No.2
Purpose: This study was conducted to identify the relationships between various factors, including compassion fatigue, compassion satisfaction, depression, anxiety, and sleep disorders among oncology nurses. Methods: A convenience sample of 140 oncology nurses from 3 university hospitals completed questionnaires. The collected data were analyzed using t-tests, ANOVA, Pearson’s correlation coefficients, and Kruskal-Wallis tests. Results: Compassion fatigue is composed of secondary traumatic stress and burnout. The levels of compassion fatigue showed significant positive correlations with depression, anxiety, and sleep disorder. On the other hand, the levels of compassion satisfaction showed significant negative correlations with compassion fatigue, depression, anxiety, and sleep disorders. The subjects in the at-risk and very distressed group of compassion fatigue and compassion satisfaction risk profile had significantly higher levels of depression, anxiety, and sleep disorders. Conclusion: Such efforts will help reduce the level of depression, anxiety, and sleep disorders in oncology nurses at-risk of developing compassion fatigue. It is also necessary to provide organization support for oncology nurses, and to develop an intervention that is designed to mitigate their compassion fatigue and to promote compassion satisfaction.
김성자(SJ Kim),강옥희(OK Kang),박찬무(CM Park) 대한산부인과학회 1977 Obstetrics & Gynecology Science Vol.20 No.9
오염된 혈액의 수혈에 의하여 발생된 패혈성 shock의 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Septic shock caused by contaminated blood transfusion is a very rare and grave condition. The mortaliy rate is relatively high ranging 50 to 70%. A case of septic shock caused by contaminated blood tranfusion is presented sith the bridf review of literatures.