의치상 레진의 세포독성에 관한 연구

김성균,장익태,허성주,곽재영,Kim Seong-Kyun,Chang Ik-Tae,Heo Seong-Joo,Keak Jai-Young 대한치과보철학회 2002 대한치과보철학회지 Vol.40 No.4

The purpose of this study was to investigate the cytotoxicity and mutagenicity of denture base resins. According to manufacturer's instructions, resin specimens were made. Group 1 : heat-polymerizing acrylic resin (Luciton $199^{(R)}$) Group 2 : heat-polymerizing acrylic resin containing polyhedraloligosilsesquioxane(POSS resin) Group 3 : auto-polymerizing acrylic resin (Repair $Acrylic^{(R)}$) Group 4 : direct relining auto-polymerizing acrylic resin (Tokuso $Rebase^{(R)}$). Fresh specimens 24 hrs. and 72 hrs. soaked specimens in distil)ed water were made. Responses with metabolic assay and mutagenesis assay to eluates from resin specimens were measured. Cultures with medium alone provided controls. Cytotoxicity was assessed with agar overlay test. The results were as follows; 1. Group 4 showed higher cytotoxicity than Group 1, Group 2 and Group 3 in fresh, 24-an4 72-hour immersion caries (p<.05). Group 3 showed higher cytotoxicity than Group 2 in fresh cases and showed higher cytotoxicity than Group 1 and Group 2 in 24-and 72-hour immersion cases (p<.05) . Group 1 and Group 2 showed no significant difference. 2. All acrylic denture base resins skewed significant increase of cell activity as immersion time increased (p<.05). 3. Auto-polymerizing acrylic denture base resins skewed higher cytotoxicity than heat-polymerizing acrylic denture base resins (p<.05). 4. All acrylic denture base resins showed lower mutagenicity than controls (p<.05).

전주시 객사길 보행자 중심 걷고 싶은 거리 설계 - 주민참여형 가로설계 -

김성균,정태영,Kim Sung-Kyun,Jeong Tae-Young 한국조경학회 2005 韓國造景學會誌 Vol.33 No.3

This paper presents a streetscape design for the 'Gaeksa-gil', located in Gosa-dong and Jungang-dong, Jeonju City, which length is about 830m and width is about $8\sim10m$. The goals of the design are to make a street on which people want to walk and rest both safely and pleasantly. To achieve these goals; concepts of identity, history, placeness, commercial vitality, environmentally-friendliness, safety, amenity , and democracy have been developed. For the pedestrian safety; shared street concepts, such as crank, salalom, fort, mini-rotary etc. are adopted. For design method, community participatory design is adapted. For the design theme; the axes of Time and Space are developed and streets are divided into 3 thematic spaces, such as 'History Street,' 'Nature Street,' and 'Culture Street.' The History Street, which belongs to Time axis, is a space for experiencing past, present, and future history of Jeonju city. Nature Street, which belongs to Space axis, is a space for feeling and loaming the nature of the city. The Culture Street, which also belongs to Space axis, is a space for experiencing the culture of the city. The community participated in the whole design process through the workshop, the internet website, the street events, etc.

벼의 ${\alpha}-Glucosidase$에 의한 Ascorbic acid로부터 Ascorbic acid-2-Glucoside의 생산

김성균,황기철,방원기,Kim, Sung-Kyoon,Hwang, Ki-Chul,Bang, Won-Gi 한국응용생명화학회 2000 Applied Biological Chemistry (Appl Biol Chem) Vol.43 No.1

Ascorbic acid로부터 $2-O-{\alpha}-D-glucopyranosyl-L-ascorbic$ acid (AA-2G)를 생산하기 위하여, transglucosylation 활성을 가지는 발아미의 ${\alpha}-glucosidase$를 효소원으로 이용하였다. 시험한 6 품종의 벼중에서 일품벼의 ${\alpha}-glucosidase$ 활성이 125.0 unit/ml로 가장 높았으며, 발아후 3일째에서 최대 비활성 8.52 unit/ml protein을 보였다. 일품벼의 조효소액을 이용한 AA-2G 생산에 있어서 glucose 공여체로는 maltose가 가장 좋았으며, maltose와 ascorbic acid의 최적 농도는 각각 125 mM와 175 mM이었다 ${\alpha}-Glucosidase$ 농도는 100 unit에서 가장 좋았으며, 효과적인 완충용액은 sodium citrate였고, 최적 농도는 100 mM이었다 최적 pH 및 반응은도는 각각 5.0과 $60^{\circ}C$이었다. 상기의 최적 반응조건 하에서 35분 반응후에 ascorbic acid로부터 $108.43\;{\mu}M/unit$의 AA-2G가 생산되었으며, 전환율은 ascorbic acid에 대해 6.2%였다. For the enzymatic production of $2-O-{\alpha}-D-glucopyranosyl-L-ascorbic$ acid (AA-2G) from ascorbic acid, rice seed was used as the source of ${\alpha}-glucosidase$ having transglucosylation activity. Among six rice varieties, cultivated in Korea, ${\alpha}-glucosidase$ activity of Oryza savita L. cv. Ilpumbyeo was the highest with 125.03 unit/ml and it had maximum specific activity with 8.52 unit/mg protein when rice seeds were grown for 3 days after germination. For the production of AA-2G using crude extract of O. savita L. cv. Ilpumbyeo, maltose was most effective glucose donor. The optimum concentration of maltose and ascorbic acid were 125 mM and 175 mM, respectively. The optimum concentration of ${\alpha}-glucosidase$ was 100 unit. The most effective buffer was 100 mM sodium citrate. The optimum pH and temperature were 5.0 and $60^{\circ}C$, respectively. Under the optimum condition, $108.43\;{\mu}M/unit$ of AA-2G was produced from ascorbic acid after 35 minutes of reaction, which corresponds to 6.2% of conversion ratio based on the amount of ascorbic acid used.

$0.13{\mu}m$ RF CMOS 공정용 스케일러블 인덕터 모델링

김성균,안성준,김병성,Kim, Seong-Kyun,Ahn, Sung-Joon,Kim, Byung-Sung 대한전자공학회 2009 電子工學會論文誌-TC (Telecommunications) Vol.46 No.1

본 논문에서는 RF 집적회로 설계를 위한 $0.13{\mu}m$ RF CMOS용 인덕터 라이브러리를 개발하였다. 스케일러블 모델링을 위해 선폭, 회전수, 내경을 조절하여 다수의 인덕터 패턴을 제작하고, 정확한 패드 효과 보상을 위해 급전 구조를 최적화하였다. 제작된 패턴의 S-파라미터 측정 데이터를 이용하여 각 소자별로 이중-$\pi$ 등가회로 소자값을 추출한 뒤 이 값들을 인덕터의 물리적 설계 변수의 함수로 표현하는 스케일러블 모델링을 수행하였다. 개발된 라이브러리는 표준(standard) 구조와 대칭(symmetric) 구조를 가지는 두 종류의 스케일러블 인덕터 모델을 제공하며, 모델 유효 주파수는 30GHz 또는 자기공진주파수까지이다. 표준구조 인덕터의 경우 $0.12{\sim}10.7nH$의 인덕턴스를, 대칭구조 인덕터의 경우는 $0.08{\sim}13.6nH$의 인덕턴스를 갖는다. 본 연구를 통해 최종적으로 10%이하의 오차를 가지는 RF CMOS용 인덕터 라이브러리를 완성하였다. This paper presents scalable modeling of spiral inductors for RFIC design based on $0.13{\mu}m$ RF CMOS process. For scalable modeling, several inductor patterns are designed and fabricated with variations of width, number of turns and inner radius. Feeding structures are optimized for accurate de-embedding of pad effects. After measuring the S parameters of the fabricated patterns, double-$\pi$ equivalent circuit parameters are extracted for each device and their geometrical dependences are modeled as scalable functions. The inductor library provides two types of models including standard and symmetric inductors. Standard and symmetric inductors have the range of $0.12{\sim}10.7nH$ and $0.08{\sim}13.6nH$ respectively. The models are valid up to 30GHz or self-resonance frequency. Through this research, a scalable inductor library with an error rate below 10% is developed for $0.13{\mu}m$ RF CMOS process.

국내 지진활동 및 지각구조 연구동향

김성균,전명순,전정수,Kim, Sung-Kyun,Jun, Myung-Soon,Jeon, Jeong-Soo 대한자원환경지질학회 2006 자원환경지질 Vol.39 No.4

유라시아판 동남쪽에 위치한 한반도는 판경계로부터 수백 km 떨어진 판내지역에 해당하며, 판내부 지진은 판경계부에서의 지진에 비해 발생하는 지진에 비해 숫자가 상대적으로 적고 크기도 작을 뿐만 아니라 발생 위치도 매우 불규칙한 편이다. 이는 단층의 활동주기가 매우 길다는 것을 의미하므로, 약 2,000년 동안의 지진역사가 기록되어 있는 우리나라는 이들 자료를 정확히 분석하여 역사시대 동안에 발생한 지진의 활동도 및 특성 등을 규명하여야 한다. 역사지진의 자료에 의하면 지진활동은 조선 중기 즉 16-18 세기에 특히 활발했으며 높은 지진활동의 기간은 중국 북동부와 일치하고 있다. 이는 이 두지역의 지진활동이 밀접하게 연관되어 있음을 시사한다. 역사지진 및 계기지진 자료에 의하면 대체로 서해안쪽이 활발하며, 한반도 남동부에서 서북서 방향으로 활발한 양상을 보여준다. 우리나라에서의 근대적 지진관측은 1905년 최초로 인천관측소가 설치되어 광복이전 6개소의 지진관측소를 운영하였다. 그 후 지진관측 공백기를 거쳐 1963년 서울에 세계표준지진계가 설치되었으며 1990 년 초에 기상청은 중앙집중식 12개소의 관측소를 본격적으로 운영하기 시작하였다. 그 후 지속적인 확장을 통해 기상청에서는 속도계관측소 35개소, 가속도 관측소 75개소를, 한국지질자원연구원은 32개소의 속도계관측소, 16개소의 가속도 관측소를, 한국원자력안전기술원은 4개소의 속도계 및 가속도 관측소를, 한국전력연구원은 13개소의 속도계 및 기속도 관측소를 운영하고 있다..27개 지진의 발생원인을 분석한 결과 한반도 및 인접지역에서 발생한 지진의 대부분은 주향이동 단층 운동에 의한 메카니즘과 다소의 역단층 운동이 첨가된 단층운동 특성을 보여준다. 한반도 및 주변에서 단층작용을 일으킨 주응력 방향은 거의 수평한 동북동-서남서 방향으로 같은 판내 지역인 북동부 중국 지역의 주응력 방향과 매우 유사하고 동해 동부와는 상당한 차이를 보인다. 이는 한반도 및 그 주변에서 지진을 일으키는 주응력은 동쪽에서 유라시아판 밑으로 침강하는 태평양판의 영향뿐만 아니라 서남쪽에서 충돌하는 인도판의 영향도 상당히 작용하는 것으로 해석된다. 지각 속도구조는 지진이 발생한 진원의 위치와 지진규모를 정확히 알아내는데 필수적이다. 그 동안 국내 지진관측망 미비, 한반도 내부의 낮은 지진 발생 빈도 등의 이유로 양질의 지진자료를 구하기 어려워 지진자료를 이용한 지각속도 구조에 대한 연구가 극히 제한적으로 이루어질 수밖에 없었다. 그러나 최근에 국내의 여러 지친관측망에서 축적된 지진기록과 반사 및 굴절 탄성파 탐사를 수행하여 종합적으로 지각 속도구조를 규명하기 시작하였다. 이와 같은 인공발파를 이용한 지각속도구조를 규명하기 위해서는 많은 인원과 예산을 필요로 하므로 관련분야의 전문가들의 적극적인 참여가 필요한 상황이다. Korean Peninsula, located on the southeastern part of Eurasian plate, belongs to the intraplate region. The characteristics of intraplate earthquake show the low and rare seismicity and the sparse and irregular distribution of epicenters comparing to interplate earthquake. To evaluate the exact seismic activity in intraplate region, long-term seismic data including historical earthquake data should be archived. Fortunately the long-term historical earthquake records about 2,000 years are available in Korea Peninsula. By the analysis of this historical and instrumental earthquake data, seismic activity was very high in 16-18 centuries and is more active at the Yellow sea area than East sea area. Comparing to the high seismic activity of the north-eastern China in 16-18 centuries, it is inferred that seismic activity in two regions shows close relationship. Also general trend of epicenter distribution shows the SE-NW direction. In Korea Peninsula, the first seismic station was installed at Incheon in 1905 and 5 additional seismic stations were installed till 1943. There was no seismic station from 1945 to 1962, but a World Wide Standardized Seismograph was installed at Seoul in 1963. In 1990, Korean Meteorological Adminstration(KMA) had established centralized modem seismic network in real-time, consisted of 12 stations. After that time, many institutes tried to expand their own seismic networks in Korea Peninsula. Now KMA operates 35 velocity-type seismic stations and 75 accelerometers and Korea Institute of Geoscience and Mineral Resources operates 32 and 16 stations, respectively. Korea Institute of Nuclear Safety and Korea Electric Power Research Institute operate 4 and 13 stations, consisted of velocity-type and accelerometer. In and around the Korean Peninsula, 27 intraplate earthquake mechanisms since 1936 were analyzed to understand the regional stress orientation and tectonics. These earthquakes are largest ones in this century and may represent the characteristics of earthquake in this region. Focal mechanism of these earthquakes show predominant strike-slip faulting with small amount of thrust components. The average P-axis is almost horizontal ENE-WSW. In north-eastern China, strike-slip faulting is dominant and nearly horizontal average P-axis in ENE-WSW is very similar with the Korean Peninsula. On the other hand, in the eastern part of East Sea, thrust faulting is dominant and average P-axis is horizontal with ESE-WNW. This indicate that not only the subducting Pacific Plate in east but also the indenting Indian Plate controls earthquake mechanism in the far east of the Eurasian Plate. Crustal velocity model is very important to determine the hypocenters of the local earthquakes. But the crust model in and around Korean Peninsula is not clear till now, because the sufficient seismic data could not accumulated. To solve this problem, reflection and refraction seismic survey and seismic wave analysis method were simultaneously applied to two long cross-section traversing the southern Korean Peninsula since 2002. This survey should be continuously conducted.

면목역 만남의 광장 설계

김성균,Kim, Sung-Kyun 한국조경학회 2007 韓國造景學會誌 Vol.35 No.1

This paper presents a landscape design for the meeting plaza around the "Myeonmok" subway station. The site is located at 120-1 Myeonmok 1-dong, Jnngrang-gu, Seoul, and its area is approximately $2,664.7m^2$. The goal of the design was to make an environmentally friendly meeting and rest place which was related to the subway station. To achieve this goal, concepts of history, tradition, sense of place, community, environmental friendliness, and function were developed. For history, stone sculpture and art tiles symbolizing the paleolithic area were introduced because the site is located near an archaeological site of paleolithic min. For tradition, considering that the site is a 'sailing ship' form in terms of Pungsu theory, a sculpture symbolizing a sailing ship and paving patterns symbolizing waves were introduced. For asense of place, a grass hill, a waterfall and a pond symbolizing an old meadow for horse pasture was introduced. In addition, a multi-purpose round plaza as a meeting place for local community and subway users was proposed. A zelkova grove symbolizing a village forest was proposed for a restand relaxation area. All areas were designed to be environmentally friendly and barrier-free. Concepts for a defensible space wereadapted for safety because the site was a crime-prone area.

A STUDY ON THE EFFECTS OF CHEWING PATTERNS TO OCCLUSAL WEAR

김성균,김광남,장익태,허성주,Kim, Seong-Kyun,Kim, Kwang-Nam,Chang, Ik-Tae,Heo, Seong-Joo The Korean Academy of Prosthodonitics 1996 대한치과보철학회지 Vol.34 No.1

저작은 치아, 악골, 저작근 뿐만 아니라 근 신경계, 고위 중추까지 복합적으로 관여되는 기능적 행위이다. 저작 형태는 다양한 모양을 가지나 두 가지 전형적인 군, 즉, 전방에서 관찰 시 그 양상이 수직적이며 절단 (chopping) 운동을 하는 군과 주로 측방으로 이루어지며 연마 (grinding)를 하는 군으로 나눌 수 있다. 본 연구의 목적은 저작 형태의 차이가 교합면 마모에 미치는 영향을 조사하는 것이다. 두개 하악 관절과 저작 습관에 이상이 없으며 교합면에 수복물이 없는 치과 대학생으로 하악 운동 궤적 기록기를 이용하여 상기의 전형적인 2가지 저작 형태를 보이는 각 15명씩을 피검자로 선택하였다. 각 피검자에 대한 임상 검사를 통해 ordinal scale로 교합면 마모의 등급을 조사하여, 평균 치아 마모도와 부위에 따른 치아 마모도를 비교 조사하였다. 각 피검자에 대한 인상 채득 후 모형을 제작하고 arbitrary scale로 교합면 마모의 등급을 조사하여, 평균 치아 마모도와 부위에 따른 치아 마모도를 비교 조사하고 저작측과 비저작측 마모를 비교 조사하였으며 수평 마모면과 수직 마모면을 비교 조사하였다. 1. 평균 치아 마모도는 ordinal scale로 측정하였을 때, 절단형과 연마형간에 유의할 만한 차이가 없었다.(p >0.05) 2. 부위에 따른 치아의 마모도는 ordinal scale로 측정하였을 때, 절단형과 연마형간에 유의할 만한 차이가 없었다.(p >0.05) 3. 평균 치아 마모도는 arbitrary scale로 측정하였을 때, 절단형에 비교하여 연마형에서 높은 마모도를 보였다.(p<0.05). 4. 절단형에 비교하여 연마형은 arbitrary scale로 측정하였을 때, 구치부에서는 높은 마모도를 보였으며 전치부에서는 유의할 만한 차이가 없었다(p<0.05) 5. 구치 평균 치아 마모도와 부위에 따른 치아의 마모도는 균형측에서 절단형과 연마형간에 유의할 만한 차이를 보이지 않았다(p>0.05). 6. 전치 평균 치아 마모도와 부위에 따른 치아의 마모도는 수평 마모면과 수직 마모면 비교시, 절단형과 연마형간에 유의할 만한 차이를 보이지 않았다.(p>0.05)

임플랜트 지대주 나사와 드라이버의 설계가 보철물 장착 및 철거 시간에 미치는 영향에 관한 연구

김성균,Kim Seong-Kyun 대한치과보철학회 2005 대한치과보철학회지 Vol.43 No.2

Statement of problem. Implant screw loosening has been remained a problem in implant prosthodontics. The time needed to insert screw driver into abutment screw head should be shortened for the purpose of decreasing the chair time. Purpose. The purpose of this study was to investigate the effects of the design of abutment screw driver on the amount of time for insertion of screw driver into abutment screw head. Material and methods. Hexagonal and rectangular types of abutment screw drivers were used. The original abutment screw drivers were modified by grinding acute angle of the screw driver tip (modified drivers). Group 1 : hexagonal type abutment screw and original driver Group 2 : hexagonal type abutment screw and modified driver Group 3 : rectangular type abutment screw and original driver Group 4 : rectangular type abutment screw and modified driver UCLA lab analogues were located in acrylic resin block. The angulations of them were 0 and 20 degrees. The times needed for insertion were measured. Group 1 and 3 were used as controls. Results. 1. Group 2 showed shorter insertion time than group 1, regardless of implant angulations (p<.05). 2. Group 4 showed shorter insertion time than group 3, regardless of implant angulations (p<.05). Conclusion. Modified abutment screw drivers required less amount of time to insert screw driver into abutment screw head. Modification of abutment screw driver was beneficial.

코 내부 유로(비강) 내부 유동의 PIV해석

김성균,Kim, Sung-Kyun 대한기계학회 2002 大韓機械學會論文集B Vol.26 No.6

For the first time, airflow in the nasal cavity of a normal Korean adult is investigated experimentally by PIV measurement. Nasal airflow can be subdivided into two interrelated categories; nasal airflow resistance and heat and mass transfer between the air stream and the walls of the nasal cavity. In this study, thanks to a new method for the model casting by a combination of the rapid prototyping and curing of clear silicone. a transparent rectangular box containing the complex nasal cavity can be made fur PIV experiments. The CBC PIV algorithm is used for analysis. Average and RMS distributions are obtained for inspirational and expiration nasal airflows. Data fer the airflow at the end of meatuses are obtained for the first time. Comparisons between western and Korean nasal airflows are appreciated. Due to the difference in geometry of the frontal part of nasal cavity, the flow near nares shows the difference.

중력탐사에 의한 옥천대 남서부의 지하지질구조(1)

김성균,안건상,오진용,Kim, Sung Kyun,Ahn, Kun Sang,Oh, Jinyong 대한자원환경지질학회 1997 자원환경지질 Vol.30 No.4

As a part of the study to know the deep geological structure of the Ogcheon Zone. gravity survey is performed along the survey line of which direction is roughly perpendicular to major faults of the Zone. Recent studies for petrology. geochemistry. and structural geology in south-western Ogcheon Zone are outlined. Raw gravity data are corrected to obtain Bouguer anomalies and the anomalies are interpreted to obtain subsurface structures along the survey line. The subterranean density discontinuities determined from the power spectrum method are appeared at depths of 15.4 km and 2.8 km. It is considered that the depth of 15.4 km indicates the boundary between upper and lower crust. Probably the depth of 2.8 km represents the boundary between upper volcanic formations and granites. Alternatively. the observed Bouguer anomalies are interpreted in terms of lateral density variation model. Finally. the subterranean geological structure to satisfy the Bouguer anomalies is presented through the iterative forward method in which results obtained from surface geological informations and from the inverse method are adopted as an initial model.