http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
대간간학회지 제6차 춘계학술대회 초록집 : 포스터 발표 ; HBs Ag 양성인 간경변증 환자에서 일시적인 혈중 alpha fetoprotein 상승의 간암 발생에 대한 의의
이상우 ( Lee Sang U ),문희석 ( Mun Hui Seog ),박기오 ( Park Gi O ),이엄석 ( Lee Eom Seog ),김선문 ( Kim Seon Mun ),서승원 ( Seo Seung Won ),양현웅 ( Yang Hyeon Ung ),성재규 ( Seong Jae Gyu ),이승민 ( Lee Seung Min ),이병석 ( Lee B 대한간학회 2000 Clinical and Molecular Hepatology(대한간학회지) Vol.6 No.1(S)
출혈성 소화성 궤양 환자에서 재출혈의 위험인자 및 재출혈률
서승원(Seung Won Seo),김연수(Yeon Soo Kim),문희석(Hee Seok Mun),박기오(Ki Ho Park),이엄석(Eom Seok Lee),김선문(Seon Mun Kim),양현웅(Hyeon Woong Yang),나병규(Byung Kyu La),성재규(Jae Kyu Seong),이병석(Byung Seok Lee),정현용(Hyun Yong 대한소화기학회 2002 대한소화기학회지 Vol.39 No.2
Background/Aims: Bleeding from peptic ulcer is a common and serious complication. Endoscopic therapy is effective in hemostasis of active bleeding. However, rebleeding occurs in 10-30% of patients with bleeding peptic ulcer, and is an important factor associated with mortality. In this study, we analyzed risk factors and rate of rebleeding in patients with bleeding peptic ulcer. Methods: We analyzed 194 patients with peptic ulcer bleeding between June 1995 and May 1998. We retrospectively analyzed the rebleeding risk factors by reviewing medical records and telephone interviews. Results: Rebleeding of peptic ulcer occurred in 43 patients (22.2%). Cumulative rebleeding rate was 12.1% after 1 month, 15.2% after 6 months. The cumulative rebleeding rates at 1, 2, and 3 years were 16.2%, 19.4% and 20.9%, respectively. On the basis of an univariate analysis of clinical and endoscopic findings, significant predictive factors for rebleeding were history of peptic ulcer bleeding (p=0.002), use of NSAIDs (p=0.08), endoscopic stigmata of recent hemorrhage (p=0.000), and presence of shock (p=0.002). In multivariate analysis, history of peptic ulcer bleeding (odds ratio, OR=9.12), use of NSAIDs (OR=7.91), endoscopic stigmata of recent hemorrhage (OR=0.37), and presence of shock (OR=3.83) were independent risk factors of rebleeding. Conclusions: Rebleeding rate of peptic ulcer is 20.6% during 3 years of follow-up and important risk factors of rebleeding are history of peptic ulcer bleeding, use of NSAIDs, endoscopic stigmata of recent hemorrhage, and presence of shock. (Korean J Gastroenterol 2002;39:101-107)
대한간학회지 제8차 춘계학술대회 초록집 : 포스터 발표 ; 화농성 간농양의 임상적 고찰
나병규 ( Na Byeong Gyu ),서승원 ( Seo Seung Won ),강윤세 ( Kang Yun Se ),김연수 ( Kim Yeon Su ),문희석 ( Mun Hui Seog ),박기오 ( Park Gi O ),이엄석 ( Lee Eom Seog ),김선문 ( Kim Seon Mun ),성재규 ( Seong Jae Gyu ),이병석 ( Lee Bye 대한간학회 2002 Clinical and Molecular Hepatology(대한간학회지) Vol.8 No.2(S)
HBsAg 양성 간경변증 환자에서 일시적인 혈중 alpha fetoprotein (α-FP) 상승의 간세포암종 발생에 대한 의의
이헌영 ( Lee Heon Yeong ),정재훈 ( Jeong Jae Hun ),강윤세 ( Kang Yun Se ),김연수 ( Kim Yeon Su ),문희석 ( Mun Hui Seog ),박기오 ( Park Gi O ),이엄석 ( Lee Eom Seog ),김선문 ( Kim Seon Mun ),서승원 ( Seo Seung Won ),이상우 ( Lee Sa 대한소화기학회 2004 대한소화기학회지 Vol.43 No.4
Background/Aims: Serum alpha fetoprotein (α-FP) measurement has a limitation to detect hepatocellular carcinoma (HCC) because it is elevated in various liver diseases. Therefore, we studied the sensitivity and specificity of high α-FP in the diagnosis of HCC. Methods: We studied 253 patients with HBsAg positive liver cirrhosis prospectively. We analyzed incidence of HCC related cut-off values of serum α-FP levels. During the follow-up period, we analyzed sensitivity and specificity of cut-off values of α-FP for the diagnosis of HCC, and α-FP elevation rate in relation to mass size. Results: One hundred and twenty-five patients had a transient elevation of α-FP levels above 20 ng/mL. The corresponding incidences of HCC were 27.2% (34/125) and 15.6% (20/128 patients without elevation of α-FP), respectively with a statistically significant difference (p=0.03). Among 54 patients with HCC, 18 patients (33.0%) had levels of α-FP below 20 ng/mL on the time of diagnosis of HCC. When we defined cut-off values of serum α-FP as 20, 100 and 500 ng/mL, the corresponding sensitivity and specificity for HCC were 62.9% and 24.0%, 7.4% and 54.2%, 77.3% and 91.9%, respectively. We studied sensitivity according to cut-off values of α-FP defined as 20, 100, 200, 500 ng/mL in patients with small HCC below 2 cm. The corresponding sensitivity were 50.0%, 43.7%, 25.0%, 18.7%, respectively. In patients with levels of serum α-FP below 20 ng/mL, percentages of mass size less than 2 cm, 2~3 cm, 3~5 cm and more than 5 cm were 50.0%, 25.0%, 28.5% and 25.0%, respectively. Conclusions: We suggested that in order to detect HCC, careful periodic monitoring with α-FP, ultrasonography and abdominal computed tomography is needed in patients with HBsAg positive liver cirrhosis and whose serum level of α-FP is above 20 ng/mL. (Korean J Gastroenterol 2004;43:252-259)
위의 원발성 악성 림프종의 임상적 특성 : MALT림프종을 포함하여
이병석,이엄석,김선문,양현웅,서승원,정현용 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1
Primary gastric lymphoma is the most common in extralymphoid and gastrointestinal lymphoma and clinical feature is variable. We reprted clinical feature of primary gastric lymphoma. Seventeen cases of primary gastric lymphoma were analyzed retrospectively from March, 1996 to December, 2000. Clinical feature and endoscopic finding with pathologic finding were analyzed. Mean age of patients was 57.6 years and M/F ratio was 1.12 to 1. The most frequent initial symptoms were epigastric discomfort and weight loss (each 47.1%). Endoscopic findings were ulcerofungating and ulceroinfiltrative lesion(each 29.4%), followed by infiltrative lesion (23.4%). Primary gastric lymphoma was suggested in 7 cases, advanced gastric cancer in 5 cases and eary gastric cancer in 2 cases. According to histologic finding, MALToma was 6 cases. One case of MALToma has done Helicobacter pylori eradication therapy. The overall 2 year and 3year survival rate were 63.3% and 50.0%. Differential diagnosis of primary gastric lymphoma and gastric adenocarcinoma was difficult in endoscopic finding. But early and precise diagnosis may been important because that prognosis of primary gastric lymphoma was superior to gastric adenocarcinoma.