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김석배(Kim, Seok-bae) 한국문화융합학회 2011 문화와 융합 Vol.33 No.-
<금오산가>는 일제강점기 때 선산의 한미한 선비가 금오산을 유람하고 돌아와 지은 기행가사이다. 금오산은 고려 말에 길재가 벼슬을 버리고 금오산에 은거하며 제자를 가르치면서 그곳은 절의정신을 상징하는 장소요, 도학의 상징적인 공간 즉 ‘理念의 聖所’였다. 본고에서는 <금오산가>에 대한 전반적인 이해에 기여하고자 선행연구의 미진한 부분과 주석의 부족한 부분을 재검토하였다. 본고에서 살펴본 바를 간략하게 정리하면 다음과 같다. 첫째, <금오산가>는 일제강점기에 선산의 한미한 선비가 우국충정에서 창작한 기행가사이다. <금오산가>는 금오산 일대를 돌아본 감회를 읊은 기행가사로 공간의 이동에 따른‘ ①대혜계곡 입구 → ②채미정 → ③야은굴 → ④대혜폭포 → ⑤금오산성 → ⑥약사암 → ⑦후망대 → ⑧경은선생 유지’ 순으로 전개되어 있다. 그리고 전체 10단이 서사, 본사, 결사로 구성되어 있다. 둘째, <금오산가>의 작자는 선산 군민들에게 길재, 이맹전의 충절과 열녀 약가의 행실을 본받아 나라 잃은 부끄러움을 씻자고 하였다. 셋째, 선행연구에서 발견되는 미비한 부분을 수정하고 보완하였다. <Geumosanga(Song of Geumo Mountain)> is a journey lyrics that a humble scholar wrote after visiting Geumo mountain who lived in Sunsan during the Japanese colonial period. Geumo mountain was the place where Giljae retired to hermitage in the mountain and trained disciples in the korea dialect, representing his faithful mind and the iconic place of Dohak, ie, the holy place of ideology . In this paper, unsatisfied part of previous studies and annotations were reviewed to contribute to the overall understaing of the <Geumosanga(Song of Geumo Mountain)>. Brief discussions in this paper can be summarized as follows. First, <Geumosanga(Song of Geumo Mountain)> is a journey lyrics that a humble scholar who lived in Sunsan wrote with patriotic sentiments during the Japanese colonial period. <Geumosanga(Song of Geumo Mountain)> is a journey lyrics that recited emotions after sightseeing Geumo mountain districts, and was written in accordance with space to move ① Daehye valley entrance → ② Chaemijeong → ③ Yaeun cave → ④ Daehye falls → ⑤ Geumo mountain castle → ⑥ Yaksaam → ⑦ Hoomangdae → ⑧ Sir Gyeongeun s maintains . And the whole 10 columns are consist of preface, body, and closing. Second, the author of <Geumosanga(Song of Geumo Mountain)> gave appeal to Sunsan county for clean sense of shame of losing this great country after Giljae and Lee Maengjeon s loyalty and a virtuous woman Yakga s behavior. Third, incompleteness of previous studies was modified and supplemented.
Assessment and therapeutics of coagulation abnormality in cirrhosis
김석배 ( Seok Bae Kim ) 대한간학회 2017 간학회 싱글토픽 심포지움 Vol.2017 No.2
The human hemostasis system is very complex and the patients with liver disease have a variety of hemostatic abnormalities. The “rebalanced hemostasis” increase risks of bleeding as well as thrombosis. The most difficulty in the assessment of patients with liver disease is that there are no established laboratory tests that accurately reflect the changes in both the procoagulant and anticogulant systems. This topic will discuss the physiology, assessment and therapeutics of coagulation abnormality in patients with liver disease.
만성 B형간염 환자에서 심한 피부 발진을 보인 라미부딘 부작용 1예
김석배 ( Seok Bae Kim ),서평주 ( Pyoung Ju Seo ),백두산 ( Du San Baik ),윤세영 ( Se Young Yun ),김병하 ( Byung Ha Kim ),신정은 ( Jung Eun Shin ),김홍자 ( Hong Ja Kim ),송일한 ( Il Han Song ) 대한소화기학회 2006 대한소화기학회지 Vol.48 No.4
Lamivudine is widely used for the treatment of chronic hepatitis B infection because of it`s remarkable antiviral efficacy and safety. We report a case of severe skin eruption caused by lamivudine. A 47-year-old female was admitted because of jaundice and itching sensation. She was diagnosed as chronic hepatitis B infection a few years ago but did not receive any specific treatment. Laboratory data showed acute deterioration of chronic hepatitis B infection. We prescribed lamivudine as a rescue therapy. Her general condition improved and lab data showed improvement in liver function test thereafter. However, she complained of severe skin eruption and itching sensation a few days after the discharge. We stopped lamivudine because the symptoms did not improve despite the use of anti-histamine. Skin biopsy showed interface dermatitis. After stopping lamivudine, her symptoms improved. However, the skin eruption developed again after lamivudine was restarted. Adefovir was used instead, and the patient did not experience any further skin problems since then. (Korean J Gastroenterol 2006;48:281-285)
김배환 ( Bae Hwan Kim ),이준혁 ( Joon Hyuk Lee ),백두산 ( Du San Baik ),윤승욱 ( Seoung Wook Yun ),김지환 ( Ji Hwan Kim ),공재환 ( Jae Hwan Kong ),김석배 ( Seok Bae Kim ) 대한소화기학회 2007 대한소화기학회지 Vol.50 No.6
Gastrointestinal stromal tumor (GIST) is an uncommon mesenchymal tumor of the gastrointestinal tract and is generally located in the stomach and small intestine. They usually present with abdominal pain, gastrointestinal bleeding, and palpable mass. Some patients present with rare symptoms that are more common in malignant GIST. Malignant GIST combined with a liver abscess has not been reported yet in the literatures. We report a case of 67-year-old woman who suffered from liver abscess combined by malignant GIST with central necrosis and fistula in the ileum. She complained of fever, chills, and abdominal pain. Abdominal CT scan showed huge liver abscess and ileal mass with air pocket. Small bowel series showed contrast material filling into the ileal GIST mass. An operation was performed and the final diagnosis was malignant GIST of the ileum with invasion into the sigmoid colon and urinary bladder. (Korean J Gastroenterol 2007;50:393-397)
나운태 ( Woon Tae Na ),이태희 ( Tae Hee Lee ),이병석 ( Byung Seok Lee ),김석현 ( Seok Hyun Kim ),채희복 ( Hee Bok Chae ),김석배 ( Seok Bae Kim ),김용석 ( Yong Seok Kim ),김선문 ( Sun Moon Kim ),임의혁 ( Euyi Hyeog Im ),허규찬 ( Ky 대한소화기학회 2010 대한소화기학회지 Vol.56 No.6
Background/Aims: Cystic lymphangioma is an uncommon disease, and rarely develops in the intraabdomen. The aim of this article was to discuss about clinical characteristics of intraabdominal cystic lymphangioma developed in Korea. Methods: Age, sex, symptoms, locations and size of the lesions, diagnostic methods, treatments, complications and recurrence were analyzed in 13 pathologically confirmed cases of intraabdominal cystic lymphangioma and 18 cases of literature consideration reported in Korea. Results: Intraabdominal cystic lymphangioma commonly developed in adults compared to the other lymphangioma, and frequently located in the mesentery. Abdominal pain was the most common symptom, but it was a non-specific finding. Tenderness and abdominal mass were not significantly associated. The size of mass was diverse. Abdominal ultrasonography and abdominal CT were diagnostic tools most commonly used, but preoperative diagnosis was possible only in 22.6%. All patients were discharged without any complications, and no recurrence was reported. Conclusions: Preoperative diagnosis of intraabdominal cystic lymphangioma is difficult and symptoms and signs are not specific. Intraabdominal cystic lymphangioma should be suspected in patients with non specific abdominal pain and intraabdominal mass and active diagnostic evaluation is mandatory. (Korean J Gastroenterol 2010;56:353-358)
만성간염 환자에서 간 섬유화의 조직학적 활성도 예측에 대한 혈청학적 표지자의 유용성
방창석 ( Chang Seok Bang ),강하얀 ( Ha Yan Kang ),최규호 ( Gyu Ho Choi ),김석배 ( Suk Bae Kim ),이원애 ( Wonae Lee ),송일한 ( Il Han Song ) 대한소화기학회 2017 대한소화기학회지 Vol.69 No.5
Background/Aims: The invasiveness of a liver biopsy and its inconsistent results have prompted efforts to develop noninvasive tools to evaluate the severity of chronic hepatitis. This study was intended to assess the performance of serum biomarkers for predicting liver fibrosis in patients with chronic viral hepatitis. Methods: A total of 302 patients with chronic hepatitis B or C, who had undergone liver biopsy, were retrospectively enrolled. We investigated the diagnostic accuracy of several clinical factors for predicting advanced fibrosis (F≥3). Results: The study population included 227 patients with chronic hepatitis B, 73 patients with chronic hepatitis C, and 2 patients with co-infection (hepatitis B and C). Histological cirrhosis was identified in 16.2% of the study population. The grade of porto-periportal activity was more correlated with the stage of chronic hepatitis compared with that of lobular activity (r=0.640 vs. r=0.171). Fibrosis stage was correlated with platelet count (r=-0.520), aspartate aminotransferase to platelet ratio index (APRI) (r=0.390), prothrombin time (r=0.376), and albumin (r=-0.357). For the diagnosis of advanced fibrosis, platelet count and APRI were the most predictive variables (AUROC=0.752, and 0.713, respectively). Conclusions: In a hepatitis B endemic region, platelet count and APRI could be considered as reliable non-invasive markers for predicting fibrosis of chronic viral hepatitis. However, it is necessary to validate the diagnostic accuracy of these markers in another population. (Korean J Gastroenterol 2017;69:298-307)