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김동석,최중언,김세혁,양국희,김현숙,Kim, Dong-Seok,Choi, Joong-Uhn,Kim, Se-Hyuk,Yang, Kook-Hee,Kim, Hyeun-Sook 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.1
Objectives and Importance : The present study investigated the levels of basic fibroblast growth factor(bFGF) in the CSF of patients with moyamoya disease and its clinical significance. Methods : The levels of bFGF in CSF, taken from 26 hemispheres of 14 moyamoya patients and 20 patients without vascular anomaly(control group), were measured by an enzyme-linked immunosorbent assay. We analyzed the correlation between the level of bFGF and the clinical factors such as age, onset pattern, development of neovascularization, and cerebral circulation. Results : The CSF of moyamoya patients contained a high concentration of bFGF to a significant extent. The bFGF level was apparently elevated in the patients in whom neovascularization from indirect revascularization, such as modified encephalo-duro-arterio-synangiosis(EDAS) was well developed. A linear correlation between the values of bFGF and clinical progression was noted. Conclusions : The elevation of bFGF in moyamoya disease seems to be specific. Clinically, the bFGF level may be considered a useful indicator to predict the efficacy of indirect revascularization.
임펄스 UWB 네트워크에서의 일정진폭 다중접속 채널코딩
김동석(Tongsok Kim),김용철(Yong Cheol Kim) 대한전자공학회 2008 電子工學會論文誌-SC (System and control) Vol.45 No.6
이 논문은 임펄스 UWB 시스템을 위한 새로운 일정진폭 프리코딩을 제안한다. IEEE 802.15.4a 표준에 따르면 임펄스 UWB는 실내측위와 센서 데이터 전달에 사용될 수 있다. 대부분의 USN(ubiquitous sensor network)은 다중접속을 필요로 한다. 그러나 UWB 시스템은 다중접속으로 야기되는 중첩신호를 검출하는데 있어 제약성이 있다. 이를 극복하기 위하여 Wada 및 Kim의 CAMC(constant amplitude multi-code) 개념을 응용하였다. 제안하는 시스템은 체계적 일정진폭 프리코딩과 LDPC 디코딩으로 구성된다. 또한 컴퓨터 시뮬레이션을 통하여 BER 성능이 우수함을 확인하였다. In this article a novel constant amplitude precoding for impulse UWB system is proposed. According to IEEE 802.15.4a, impulse UWB can be used in indoor localization and sensor data transmission. Most USN(ubiquitous sensor networks) needs multiple access. However impulse UWB system has a limited capability to detect superpositioned signal induced by multiple access. To overcome this problem we have adopted the concept of CAMC(Constant Amplitude Multi-Code) deviced by Wada and Kim. The proposed system consists of systematic constant amplitude precoding and LDPC decoding. And this system shows a good BER performance in computer simulation.
김동석,이은희,김기권,김미진,이수정,Kim, Dong-Sug,Lee, Eun-Hi,Kim, Ki-Kwon,Kim, Mi-Jin,Lee, Soo-Jung 대한세포병리학회 1995 대한세포병리학회지 Vol.6 No.1
This study was carried out to determine the usefulness of imprint cytology for detecting p53 protein in breast carcinoma. NCL-DO7 (Novocastra, U.K.) was used to detect p53 protein immunocytochemically. A total of 33 cases was studied, Immunostaining of imprint cytology with NCL-DO7 was positive in 64% (21/33) and showed relatively high coincident rate (80%) with immunostaining of formalin-fixed, paraffin-embedded specimen p53 protein was related to negative estrogen receptor status, but not to the nuclear grade, lymph node metastasis, or tumor size. The fact that p53 protein expression was not related to nuclear grade might be due to predominance of nuclear grade 3. It was easier to determine the nuclear grade is one of the most important prognostic factors, in imprint cytology than in tissue specimen. p53 protein tended to be stained more strongly in imprint cytology than in tissue. It is concluded that the application of imprint cytology in p53 protein detection can be performed easily, and that it may contribute to the evaluation of prognostic factors in breast carcinoma.
서로 다른 산포를 허용하는 이변량 영과잉 음이항 회귀모형
김동석,정슬기,이동희,Kim, Dong-Seok,Jeong, Seul-Gi,Lee, Dong-Hee 한국통계학회 2011 Communications for statistical applications and me Vol.18 No.5
본 연구에서는 두 반응 변수에 서로 다른 산포를 허용하는 새로운 이변량 영과잉 음이항 회귀모형을 제안하고, Deb과 Trivedi (1997)에 나타난 헬스케어 자료를 이용하여 두 반응변수가 갖는 서로 다른 산포도를 무시한 Wang (2003)이 제안한 이변량 영과잉 음이항 회귀모형과의 효율성을 로그우도와 AIC의 관점에서 비교 하였다. 모형적합결과, 본 연구에서 제안한 모형이 모형선택기준 관점에서 기존모형에 비하여 월등히 우수한 결과를 보여주었다. We propose a new bivariate zero-inflated negative binomial regression model to allow heterogeneous dispersions. To show the performance of our proposed model, Health Care data in Deb and Trivedi (1997) are used to compare it with the other bivariate zero-inflated negative binomial model proposed by Wang (2003) that has a common dispersion between the two response variables. This empirical study shows better results from the views of log-likelihood and AIC.
LNG Tank용 자기충전 콘크리트의 배합설계에 관한 연구
김동석,박상준,원철,이상수,Kim, Dong-Seok,Park, Sang-Joon,Won, Cheol,Lee, Sang-Soo 한국건축시공학회 2004 한국건축시공학회지 Vol.4 No.1
The purpose of this study was to design the self-compaction concrete mixture, having not only high strength but also compensation of shrinkage without thermal crack under 4 sides outer restraint of the member. In the experimental mix, replacement ratio of limestone Powder, CSA expansive additives, and unit water were selected as parameters, using portland blast-furnace slag cement. And, bleeding test, expansibility test. hydration heat analysis were performed. As a results, when 35% of limestone Powder, 6% CSA expansive additives are replaced at unit water 175kg/$\textrm{m}^3$, demanded performances of fresh and hardened self-compaction concrete are accomplished.
유전체 장벽 방전 플라즈마 방전수의 특성과 미생물 소독에 관한 연구
김동석,박영식,Kim, Dong-Seog,Park, Young-Seek 한국환경보건학회 2012 한국환경보건학회지 Vol.38 No.2
Objectives: This experiment was carried out to elucidate the effect of discharged water on the disinfection of $Phytophthora$ $capsici$ and evaluate the water characteristics. Methods: The dielectric barrier discharges (DBD) plasma reactor system used in this study consisted of a plasma component [discharge, ground electrode and quartz dielectric tube], high voltage source, and air supply. The effects of water characteristics such as pH, ORP and conductivity and the disinfection effect of discharged water were investigated. Results: Experimental results showed that in the process of discharge, the pH decreased, whereas ORP and electric conductivity increased. When the discharge time was 30 min, $Phytophthora$ $capsici$ of 2.94 log was disinfected within 300 seconds. Disinfection performance of stored discharged water was maintained for three days; however the disinfection effect vanished after five days. When $Phytophthora$ $capsici$ was injected into the discharged water, the disinfection effect decreased after two days. Conclusions: It is considered that the main disinfection parameters of the discharged water were chemically active species such as $H_2O_2$ and $O_3$ and high ORP.
다낭성난소 증후군 환자의 Pure Follicle-Stimulating Hormone 간헐 피하주사법을 이용한 배란유도
김동석,신승준,김혜영,이해양,박준영,박영선,Kim, D.S.,Shin, S.J.,Kim, H.Y.,Lee, H.Y.,Park, J.Y.,Park, Y.S. 대한생식의학회 1993 Clinical and Experimental Reproductive Medicine Vol.20 No.2
Polycystic ovarian syndrome (PCOS) patients have a characteristic of high leuteinizing hormone (LH) to follicle -stimulating hormone (FSH) ratio. Usually, human menopausal gonadotropin (hMG) is used to induce ovulation in clomiphene citrate-resistant PCOS patients. However, HMG contains two components, namely, LH and FSH, with 50%, respectively. Therefore, FSH is theoretically recommended to stimulate follicular maturation. From the pituitary, LH is secreted by pulsatile pattern. So, we have been using intermittent subcutaneous injection of pure FSH for ovulation induction in 10 PCOS patients from March, 1990 to August, 1992. We obtained good results by intermittent subcutaneous injection of pure FSH. Ovulation is 100% per patient, and 88.2% per cycle. Pregnancy rate is 80% per patient, and 23.5% per cycle. Ovarian hyperstimulation syndrome (OHSS) is 50% per patient, 41.2% per all cycles, and 46.7% per all ovulated cycles. In comparison with HMG, pregnancy rate per cycle is relatively low. But, ovulation rate and pregnacy rate per person is higher than HMG. Because of the strict check of ovaries by the vaginal ultrasonography, OHSS rate is relatively high.