식방풍의 성분분리 및 생리활성

김도훈,한지수,김기은,김진효,김성건,김호경,오오진,황완균,Kim, Do-Hoon,Han, Chi-Su,Kim, Gi-Eun,Kim, Jin-Hyo,Kim, Sung-Gun,Kim, Ho-Kyoung,Oh, O-Jin,Whang, Wan-Kyunn 대한약학회 2009 약학회지 Vol.53 No.3

In this study, isolation of antioxidative compounds was performed for development of anti-oxidizing agent. $CHCl_3$, $H_2O$, 30%, 60% MeOH, MeOH fractions were examined antioxidative activity by DPPH, test of inhibition on NO production. It was revealed that 30%, 60% MeOH and $CHCl_3$ fractions had significant antioxidative activity. In 30% MeOH and 60% MeOH, $CHCl_3$ fraction, six compounds were isolated and elucidated as adenosine(I), guanosine(II), peucedanol 7-O-$\beta$-D-apiofuranosyl(1$\rightarrow$6)-$\beta$-glucopyranoside(III), peucedanol 7-O-$\beta$-D-glucopyranoside(IV), peucedanol(V) and scopoletin(VI) by physicochemical data and spectroscopic methods. (Negative FAB-MS, $^{1}H-NMR$, $^{13}C-NMR$). The results from antioxidative activity screening for the each compound showed that compound IV was relatively superior antioxidant ability. In anti-inflammatory activation assay, compound III, IV, VI had concentration-dependent-activity and compound IV had superior anti-inflammatory ability. These results suggest that Peucedani Radix might be developed as a potent anti-oxidative, anti-inflammatory agents and ingredients for related functional foods.

c-$\phi$ 지반에서의 아칭현상을 고려한 원형수직터널 토압 : II. 실내 모형실험

김도훈,차민혁,이대수,김경렬,이인모,Kim, Do-Hoon,Cha, Min-Hyuck,Lee, Dea-Su,Kim, Kyung-Ryeol,Lee, In-Mo 한국터널지하공간학회 2010 한국터널지하공간학회논문집 Vol.12 No.2

원형수직터널에 작용하는 토압은 아칭효과로 인해 2차원 일반 흙막이벽에 작용하는 토압보다 작으므로 원형수직터널 설계 시 벽체에 작용하는 실질적인 토압의 예측이 필요하다. 본 논문은 두 개의 연속된 논문(Companion papers)의 두번째로서 원형수직터널 설계 시 건조한 사질토뿐만 아니라 c-$\phi$ 지반과 다층지반에서 적용 가능하도록 새롭게 제안된 토압식(김도훈 등, 2009)을 증명하기 위해 대형 모형실험을 수행하였다. 고안된 모형실험 장비는 단계별 굴착이 가능하도록 제작 벽체의 반경을 변화시켜가며 실험을 수행하였다. 또한 강사 방법으로 지반을 조성하기 전 건조한 시료에 물을 첨가하고 불포화사질토를 형성시켜 겉보기 점착력을 발현시킴으로써 c-$\phi$ 지반과 다층지반에서 실험을 진행하였다. 실험 결과로서, 단계별 굴착을 모사하였을 때, 아칭효과에 의해 굴착된 지반에서 굴착되지 않은 지반으로 하중이 전이가 일어나는 확인할 수 있었다. 또한, 동시에 굴착했을 때의 토압은 예측한 값에 비해 상당히 작게 나타났지만, 단계별로 굴착했을 때의 최종 토압은 동시 굴착 시의 토압에 비해 크게 나타나며 새롭게 제안된 토압식과 잘 일치하였고 c-$\phi$ 지반과 다층지반에서 수행한 실험의 결과도 겉보기 점착력의 효과로 인해 토압의 감소를 보이며 이론적인 값과 잘 일치하는 것으로 나타났다. The earth pressure acting on the vertical shaft is less than that acting on the retaining wall due to three dimensional arching effect. Thus, it might be essential to estimate the earth pressure actually acting on the shaft when designing the vertical shaft. In this paper, large-sized model tests were conducted as Part II of companion papers to verify the newly suggested earth pressure equation proposed by Kim et al. (2009: Part I of companion papers) that can be used when designing the vertical shaft in cohesionless soils as well as in c-$\phi$ soils and multi-layered soils. The newly developed model test apparatus was designed to be able to simulate staged shaft excavation. Model tests were performed by varying the radius of vertical shaft in dry soil. Moreover, tests on c-$\phi$ soils and on multi-layered soils were also performed; in order to induce apparent cohesion to the cohesionless soil, we add some water to the dry soil to make the soil partially-saturated before depositing by raining method. Experimental results showed a load transfer from excavated ground to non-excavated zone below dredging level due to arching effect when simulating staged excavation. It was also found that measured earth pressure was far smaller than estimated if excavation is done at once; the final earth pressure measured after performing staged excavation was larger and matched with that estimated from the newly proposed equation. Measured results in c-$\phi$ soils and in multi-layered soils showed reduction in earth pressures due to apparent cohesion effect and showed good matches with analytical results.

수중기지국 기반 수중통신망 구축 및 성능 시험

김도훈(Kim Do Hoon),채광영(Chae Kwang Young),고만재(Go Man Jae),정해지(Jeong Hae Ji),유호동(Liu Hao Dong),조용호(Cho Young Ho) 한국통신학회 2021 한국통신학회 학술대회논문집 Vol.2021 No.2

본 논문에서는 수중음향통신을 활용하여 CTD센서와 DO센서를 통해 수중환경데이터를 측정하고, 측정된 값을 육상에서 확인할 수 있도록 하는 실험을 진행하였다. 본 실험은 남해 실해역에서 20년 12월 12일부터 20일까지 진행되었으며, 구조물은 해수면에 해상부이 1대, 해저면에 수중기지국 2대, 센서노드 10대를 설치하였다. 모든 구조물에는 송신을 위한 트랜스듀서와 수신을 위한 하이드로폰이 장착된다. 해상부이는 해저면에 설치된 수중기지국과 센서노드에서 수중환경데이터를 수신한 후 육상 서버와 통신하여 패킷을 전송한다. 데이터는 1시간 단위로 전송되도록 설정하였으며 실험결과, 패킷 성공률은 약91.20%인 것을 확인하였다.

담배가격인상 효과분석

김도훈,한광환,Kim Do-Hoon,Han Kwang-Hwan 한국연초학회 2005 한국연초학회지 Vol.27 No.2

The government continuously increases cigarette price to reduce the smoking rates. Opinions of cigarette makers and Ministry of Health and Welfare on the effect of cigarette price hike are sharply opposed. This dispute is important because there is possibility of additional increase of cigarette price by 500 won. Therefore, as an inquiry into existing studies for the effect of cigarette price hike on tobacco product, namely analysis of the effect of cigarette price hike consumption, we empirically analyzed the effect of cigarette excise tax hike through establishing improved analytic models considering time trend. As a result, it is substantiated that time trend in the effect of cigarette excise tax hike is certainly exist and early impact is heavy. However, the amount of cigarette consumption is recovered to the level of the average in 5 months. Since it is proved that the long term effect of cigarette price hike is immaterial, health authority should reconsider the plan of additional raising cigarette price by 500 won.

급속 열처리가 a-IGZO 박막의 전도에 미치는 영향

김도훈,조원주,Kim, Do-Hoon,Cho, Won-Ju 한국전기전자재료학회 2016 전기전자재료학회논문지 Vol.29 No.1

The conduction behavior and electron concentration change in a-IGZO thin-films according to the RTA (rapid thermal annealing) were studied. The electrical characteristics of TFTs (thin-film-transistors) annealed by different temperatures were measured. The sheet resistance, electron concentration, and oxygen vacancy of a-IGZO film were measured by the four-point-probe-measurement, hall-effect-measurement, and XPS analysis. The RTA process increased the driving current of IGZO TFTs but the VTH shifted to the negative direction at the same time. When the RTA temperature is higher than $250^{\circ}C$, the leakage current at off-state increased significantly. This is attributed to the increase of oxygen vacancy resulting in the increase of electron concentration. We demonstrate that the RTA is a promising process to adjust the VTH of TFT because the RTA process can easily modify the electron concentration and control the conductivity of IGZO film with short process time.

모델예측제어 기법을 이용한 제지공정에서의 지종교체 제어

김도훈,여영구,박시한,강홍,Kim, Do-Hoon,Yeo, Young-Gu,Park, Si-Han,Kang, Hong 한국펄프종이공학회 2003 펄프.종이기술 Vol.35 No.4

In this work an integrated model for paper plants combining wet-end and dry section is developed and a model predictive control scheme based on the plant model is proposed. Closed-loop process identification method is employed to produce a state-space model. Thick stock, filler flow, machine speed and steam pressure are selected as input variables and basis weight, ash content and moisture content are considered as output variables. The desired output trajectory is constructed in the form of 1st-order dynamics. Results of simulations for control of grade change operations are compared with plant operation data collected during the grade change operations under the same conditions as in simulations. From the comparison, we can see that the proposed model predictive control scheme reduces the grade change time and achieves stable steady-state.

변화점을 고려한 소프트웨어 신뢰도 성장모형의 모수추정

김도훈,박천건,남경현,Kim, Do-Hoon,Park, Chun-Gun,Nam, Kyung-H. 한국통계학회 2008 응용통계연구 Vol.21 No.5

비동질적 포아송과정(NHPP) 모형은 신뢰성 공학에서 소프트웨어 내에 남아있는 결함발견현상을 설명하는데 자주 사용된다. 이때 결함발견율은 연속적이며 단조함수를 가정하였으나 현실적으로 소프트웨어 시험환경, 전략 및 자원할당 등으로 인해 결함발견율이 변하는 경우가 있다. 본 논문은 결함발견율이 변화하는 변화점 문제를 고려한 소프트웨어 신뢰도 성장모형(SRGM)을 고려하여 모수를 추정하는데 목적이 있다. 이를 위해 자료를 모의 생성한 후 평균값 함수의 각 모수를 최우추정법과 최소제곱법을 이용하여 추정하며, 결함발견구간이 일정하게 증가하는 경우와 일정하게 증가하지 않는 경우를 각각 고려한다. 이때 각 모수의 적합도 비교 평가를 통하여 변화점을 고려한 SRGM에서의 최적 추정법을 수치적 방법으로 판단한다. The non-homogeneous Poisson process(NHPP) based software reliability growth models are proved quite successful in practical software reliability engineering. The fault detection rate is usually assumed to be the continuous and monotonic function. However, the fault detection rate can be affected by many factors such as the testing strategy, running environment and resource allocation. This paper describes a parameter estimation of software reliability growth model with change-point problem. We obtain the maximum likelihood estimate(MLE) and least square estimate(LSE), and compare goodness-of-fit.

ATM LANE에서의 멀티미디어 방송형 트래픽의 Scalable한 관리를 위한 유전자 알고리즘 응용

김도훈,Kim, Do-Hoon 한국정보처리학회 2002 정보처리학회논문지 C : 정보통신,정보보안 Vol.9 No.5

Presented is a Genetic Algorithm (GA) for dynamic partitioning an ATM LANE(LAN Emulation) network. LANE proves to be one of the best solutions to provide guaranteed Quality of Service (QoS) for mid-size campus or enterprise networks with minor modification of legacy LAN facilities. However, there are few researches on the efficient LANE network operations to deal with scalability issues arising from broadcast traffic delivery. To cope with this scalability issue, proposed is a decision model named LANE Partitioning Problem (LPP) which aims at partitioning the entire LANE network into multiple Emulated LANs (ELANS), each of which works as an independent virtual LAN. 기존 LAN 환경에서 멀티미디어 실시간 전송과 같은 QoS 보장형 서비스에 대한 요구가 증대되면서, ATM 기술을 LAM에 적용하는 기술들이 등장하였다. LANE(LAN Emulation)은 그러한 기술들 중에서 캠퍼스와 기업의 네트워크 인프라로 가장 많이 보급되고 있는 대안 중의 하나이다. 그러나 활발한 LANE 도입에 비하여 이의 효과적인 운용에 대한 연구는 드문 실정이다. 본 논문에서는 LANE을 구축한 캠퍼스 네트워크에서 멀티미디어 방송형(broadcast) 트래픽의 최적 운영방안에 대하여 논의한다. 방송형 트래픽 관리에서 발생하는 규모성(scalability) 문제로 인하여 전체 LANE 네트워크는 일반적으로 여러 개의 ELAN(Emulated MU)으로 분할되어 관리된다. 본 연구는 특히 규모성 문제해결을 위한 ELAN 구성(configuration)에 수반되는 비용을 정의하고, LANE 성능에 직결되는 규모성 제약과 ELAN 운용과 관계된 기술적 제약하에서 제반비용을 최소화하는 ELAN 구성(LANE 분할) 의사결정모형을 제공한다. 이는 그래프분할문제(graph partition problem)의 확장된 형태로 모형화 되며, 제안된 수리적 모형을 위한 유전자 알고리즘 해법을 개발하여 소개한다. 또한 실제 LANE 네트워크 운영자료를 사용한 실험을 통하여 최적 ELAN 구성을 위한 정책변수들의 효과를 살펴보고, 이러한 결과들이 기존의 LANE 운영과 관련하여 가지는 함축적인 의미를 고찰한다.

전도성 고분자/CdTe 나노입자/탄소 나노튜브 복합박막의 특성 연구

김도훈,심성은,김정수,남대근,오원태,Kim, Do-Hoon,Shim, Seong Eun,Kim, Jungsoo,Nam, Dae-Geun,Oh, Weontea 한국전기전자재료학회 2013 전기전자재료학회논문지 Vol.26 No.4

The composites composed of conducting polymer (MEH-PPV), CdTe nanoparticles, and multiwalled carbon nanotubes (MWNTs) were spectroscopically and electrically characterized in their thin films. The composite films were prepared by spray coating. These composites were prepared from the mixture solution of MEH-PPV and CdTe-embedded MWNTs, in which CdTe nanoparticles were electrostatically bound to MWNTs. UV/vis and PL spectra were analyzed to investigate the optical absorbance and emission of the composite films. In addition, their structural, electrochemical, and electrical properties were studied by transmission electron microscopy, cyclic voltammetry, and I-V measurement.

임플란트 CT에서 방향 표시자의 방향과 잔존골을 고려한 임플란트 식립 방향의 관계에 관한 연구

김도훈,허민석,이삼선,오성욱,최항문,전인성,최순철,Kim Do-Hoon,Heo Min-Suk,Lee Sam-Sun,Oh Sung-Ook,Choi Hang-Moon,Jeon In-Seong,Choi Soon-Chul 대한영상치의학회 2003 Imaging Science in Dentistry Vol.33 No.2

Purpose : To assess the relationship between the direction of the indicating rod of the radiographic stent for ideal prosthetic design and the actual possible path of implant fixture placement when residual ridge resorption is considered. Materials and Methods: The study materials consisted of 326 implant sites (male 214 cases and female 112 cases) from a total of 106 patients (male 65 patients and female 41 patients) who desired implant prostheses. Computed tomography of patients were taken and reformatted using ToothPix/sup (R)/ software. Bony defects, bony sclerosis, the change of the direction of indicating rod, and root proximity of the adjacent teeth were examined on the CT-derived images. Results: The rate of the irregular crestal cortex was relatively high on premolar and molar area of maxilla. Mandibular molar area showed relatively high rate of focal sclerosis on the area of implant fixture insertion. The position of the indicating rods were relatively acceptable on the molar areas of both jaws. However, the position of the indicating rods should be shifted to buccal side with lingual rotation of the apical end on maxillary anterior teeth and premolar area. Conclusion: Clinically determined rod direction and position of the indicating rod for implant placement was not always acceptable for insertion according to the reformatted CT images. The pre-operative treatment plan for implant should be determined carefully, considering the state of the alveolar bone using the reformatted CT images.