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      • KCI등재

        Enhanced UV-Light Emission in ZnO/ZnS Quantum Dot Nanocrystals

        김기은,김웅,성윤모,Kim, Ki-Eun,Kim, Woong,Sung, Yun-Mo Materials Research Society of Korea 2008 한국재료학회지 Vol.18 No.12

        ZnO/ZnS core/shell nanocrystals (${\sim}5-7\;nm$ in diameter) with a size close to the quantum confinement regime were successfully synthesized using polyol and thermolysis. X-ray diffraction (XRD) and high-resolution transmission electron microscopy (HRTEM) analyses reveal that they exist in a highly crystalline wurtzite structure. The ZnO/ZnS nanocrystals show significantly enhanced UV-light emission (${\sim}384\;nm$) due to effective surface passivation of the ZnO core, whereas the emission of green light (${\sim}550\;nm$) was almost negligible. They also showed slight photoluminescence (PL) red-shift, which is possibly due to further growth of the ZnO core and/or the extension of the electron wave function to the shell. The ZnO/ZnS core/shell nanocrystals demonstrate strong potential for use as low-cost UV-light emitting devices.

      • KCI등재후보

        소아와 성인 $Henoch-Sch\"{o}nlein$ Purpura(HSP) 신염의 임상적 비교

        김기은,신윤호,신재일,박지민,정현주,이재승,Kim Ki-Eun,Shin Youn-Ho,Shin Jae-Il,Park Jee-Min,Jeong Hyeon-Joo,Lee Jae-Seung 대한소아신장학회 2003 Childhood kidney diseases Vol.7 No.2

        Purpose : $Henoch-Sch\"{o}nlein$ purpura(HSP) is a systemic vasculitis that involves multiple organs, especially the kidney, which is the most important organ in determining the prognosis of the disease. The morbidity of HSP nephritis in adults is low and there have been little research done on its clinical course so far. Therefore, we have compared the clinical course of HSP nephritis in children and adults in Korea. Methods : We retrospectively analyzed 81 cases of HSP nephritis in children younger than 15 years of age, and 25 cases of adults older than 15 years of age who were admitted to Yonsei University Medical College Severance Hospital from Jan. 1986 to May 2003. Results : The male to female ratio was 1.5 : 1 in children and 1.3 : 1 in adults. The incidence of HSP nephritis for both age groups was found to be increased during the autumn and winter. Infection was the predisposing factor in 39 cases(48.1%) of children, 16 cases(64.0%) of adults, and drugs were the predisposing factor in 8 cases(9.9%) of children and 4 cases (16.0%) of adults. All patients initially presented with microscopic hematuria. Thirteen cases (16.0%) of children and 7 cases(28.0%) of adults initially showed proteinuria of nephrotic range. Thirty four cases(42.0%) of children and 4 cases(16.0%) of adults showed normal urinalysis after treatment. Asymptomatic urinary abnormalities were found in 41 cases(50.6%) of children and 18 cases(72.0%) of adults. Complications such as nephrotic syndrome and hypertension were found in 3 cases(3.7%) of children and 2 cases(8.0%) of adults. Three children(3.7%) and 1(4.0%) adult required dialysis or renal transplantation. Follow-up renal biopsies were performed on 21 children, of whom 10 cases(47.6%) did not show any histologic change, 9 cases(42.9%) showed low grade changes, and 2 cases(9.5%) showed high grade changes. Prognosis was gloomy when proteinuria of nephrotic range and high grade of abnormal histology were present at diagnosis, and there was no significant difference between the two groups(P<0.05) Conclusion : This study showed that there was no difference in terms of the clinical features and courses between the children and adults with HSP nephritis. Proteinuria of nephrotic range and the severity of abnormal histologic changes at diagnosis were found to be associated with a bad prognosis, therefore we recommend that patients with these features require long term follow-up and management. 목적 : $Henoch-Sch\"{o}nlein$ purpura(HSP)는 여러 장기를 침범하는 전신성 혈관염으로 신장손상이 예후를 좌우하는 중요한 원인이 된다. 성인 HSP 신염은 빈도가 낮고 임상 경과에 대한 연구가 부족한 편이다. 소아와 성인 HSP 신염의 임상 및 경과를 전반적으로 비교함으로서 각각의 예후에 영향을 주는 인자를 알아보고자 하였다. 방법 : 1986년 1월부터 2003년 5월까지 17년 4개월간 연세대학교 세브란스병원에 내원한 15세 미만의 소아 81명과 15세 이상의 성인 25례를 대상으로 후향적으로 고찰하였다. 결과 : 남녀비는 소아 1.5:1, 성인 1.3:1이었고, 발병 계절은 두 군 모두 가을과 겨울에 발병 빈도가 증가하였다. 감염이 선행한 경우가 소아 39례(48.1%), 성인 16례(64.0%)였고, 약물을 복용한 경우는 소아 8례(9.9%), 성인 4례(16.0%)였다. 모든 환자에서 현미경적 혈뇨가 있었고 신증 범위의 단백뇨를 보인 예는 소아 13례(16.0%), 성인 7례(28.0%)있었다(Table 3). 추적 관찰에서 요검사가 정상화된 경우는 소아 34례(42.0%), 성인 4례(16.0%)였고, 무증상 요검사 이상의 예는 소아 41례(50.6%), 성인 18례(72.0%)이었다. 신증후군 또는 고혈압의 합병증이 초래된 경우는 소아 3례(3.7%), 성인 2례(8.0%)이었고, 투석 또는 이식을 받은 경우는 소아 3례(3.7%), 성인 1례(4.0%)였다(Table 4). 소아 21례에서 추적 신생검을 시행하였고 이 중 10례는 조직학적 등급의 변화를 보이지 않았고, 낮은 등급으로 호전된 경우가 9례, 높은 등급으로 악화된 경우가 2례있었다. 진단 당시 신증 범위의 단백뇨가 있었던 경우와 조직학적 등급이 높았던 경우에 나쁜 예후를 보였고(P<0.05) 이는 두 연령군에서 통계학적 차이가 없었다(Table 5). 결론 : 본 연구에서는 소아와 성인에서 임상 양상 및 경과가 두 군에서 다르지 않음을 확인하였고, 소아와 성인 두 군 모두 진단 당시 신증 범위의 단백뇨가 있거나 조직학적 등급이 높을수록 나쁜 예후를 보이므로 그에 따른 장기적인 계획과 치료가 필요할 것으로 생각된다.

      • KCI등재후보
      • KCI등재

        문학 활동을 접목한 자연체험활동의 협력적 실행연구

        김기은(Kim Ki Eun),김성희(Kim Seong Hee) 학습자중심교과교육학회 2021 학습자중심교과교육연구 Vol.21 No.12

        목적 본 연구의 목적은 문학 활동을 접목한 만 5세의 자연체험 활동의 협력적 실행연구를 실시하고 실행연구의 과정속에서 나타나는 유아의 교육적 유의미한 변화를 탐색하는 것이다. 방법 이를 위해 만 5세 담임교사와 연구자가 약 6개월간의 협력적 실행연구에 참여하였다. 주요 자료 수집은 연구자의 교사 면담과 수업참여관찰을 통하여 이루어졌으며, 참여 관찰을 통한 유아관찰, 연구자와 담임교사의 면담과 혐의자료, 유아의 활동 기록지 등의 자료를 비교⋅검토하는 방법론적 삼각측정법(methodological triangulation)을 사용하였다. 결과 연구에 참여한 유아들은 자연에 대한 관심을 가지며, 또래 집단과 협력적으로 텃밭 가꾸기를 모색하게 되는 변화를 가지게 되었다. 나아가 이를 심미적 언어로 표현하여 자연 친화적 태도 형성의 변화를 보여주었다. 결론 본 연구의 결과를 바탕으로 문학 활동을 접목한 자연체험활동의 어려움을 살펴보고 이러한 문제를 연구 참여자와 연구자가 해결해 나가는 과정을 소개하면서 유아가 활동을 통한 변화를 소개하며 협력적 실행연구의 가치에 대해 논의하였다. Objectives The purpose of this study is to conduct collaborative research on natural experience activities of 5-year-olds incorporating literary activities and to explore significant educational changes in infants in the course of the study. Methods For this purpose a 5-year-old homeroom teacher and a researcher participated in a cooperative practice study for about 6 months. Major data were collected through interviews with the researcher s teacher and observation of class participation, and a methodological triangulation method that compares and reviews data such as infant observation through participation observation, interview and suspicion data between the researcher and the homeroom teacher, and activity records (methodological triangulation) was used. Results As a result, the infants who participated in the study have an interest in nature and have a change that seeks to cultivate a garden collaboratively with their peer group. Furthermore, by expressing this in aesthetic language, it showed a change in the formation of a nature-friendly attitude. Conclusions Based on the results of this study, we looked at the difficulties of natural experience activities that combine literary activities, introduced the process by which researchers and researchers solved these problems, introduced changes in activities for infants, and discussed the value of collaborative action research.

      • KCI등재후보

        두개 이열증을 동반한 Robinow 증후군 (Fetal Face Syndrome) 1례

        김기은(Ki Eun Kim),함태영(Tai Young Ham),강두철(Doo Choel Kang),고창준(Chang Jun Coe),이준수(Joon Soo Lee) 대한소아신경학회 2003 대한소아신경학회지 Vol.11 No.2

        저자들은 경련을 주소로 내원한 환아에서 저신장을 보이며 전형적인 태아 얼굴 모양과 전완단증, 미소음경의 임상소견을 특징으로 하고 두개 이열증을 동반한 Robinow 증후군 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Robinow syndrome is a rare inherited disorder initially reported by Robinow et al. in 1969 as a new dwarfing syndrome. It is characterized by the presence of fetal face, forearm shortening, genital hypoplasia, and hemivertebrae. The autosomal recessive form of Robinow syndrome shows a more severe clinical phenotype which is expressed by the mutation of homozygous ROR2(Receptor tyrosine kinase like Orphans) gene, mapped to the chromosome 9q22, a region that overlaps the locus for autosomal dominant inherited brachydactyly type B(BDB). ROR2 encodes the receptor tyrosine kinase, which is important for the development of mesomelic long bones. We experienced a boy diagnosed as a Robinow syndrome with fetal face(frontal bossing, hypertelorism, small up-turned nose, triangular mouth with down turned angles, micrognathia), large anterior fontanelle, cranium bifidum, mesomelic shortening, cryptorchidism. We present this case with a brief review of related literature.

      • KCI등재후보
      • KCI등재

        두충나무, 황벽나무 등을 포함하는 수목추출물의 항여드름 및 항아토피 효과

        김기은 ( Gi Eun Kim ),김진홍 ( Jin Hong Kim ),홍슬기 ( Seul Ki Hong ),김타곤 ( Ta Gon Kim ),김동욱 ( Dong Uk Kim ) 한국화학공학회 2010 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.48 No.6

        본 연구에서는 두충나무, 황벽나무 등을 포함하는 수목추출물의 소재특성을 시험하여 화장품 및 피부질환 치료소재로서의 응용 가능성을 조사하였다. 수목추출물의 항산화력은 DPPH 자유라디칼 소거법으로 측정되었으며 저농도에서는 항산화력이 낮았으나, 1,000 ug/ml의 고농도에서는 우수한 항산화제인 비타민 C와 유사하였다. 항균력은 원판확산법으로 측정되었으며, 수목추출물은 피부상재균인 Staphylococcus epidermidis에 대해서는 낮은 항균력을 보이지만, 여드름 유발균인 Propionibacterium acne에 대해서는 높은 항균력을 보여주는 선택성 항균력이 있어, 여드름소재로서 매우 우수한 특성을 나타내었다. 무모생쥐를 이용한 항아토피 시험결과, 수목추출물은 DNCB에 의해 유도된 피부염증을 14일 째 거의 정상상태로 회복시켰으며, 피부내 항체인 IgE의 농도도 대조군에 비해 16% 낮추어주어 항아토피 효과가 우수한 것으로 나타났다. 따라서 수목추출물은 항여드름효과 및 항아토피 효과가 뛰어나서 화장품 혹은 피부질환치료소재로서 응용 가능성이 매우 높음을 알 수 있었다. In this study, plant extracts including Eucommia ulmoides Oliv, and Phellodendron amurense were studied to test possible application for cosmetics and skin related medicine. Anti-oxidation effect of plant extracts was measured by DPPH free radical scavenging activity and it was insignificant at low concentration, however, it was as good as vitamin C, excellent anti-oxidation agent, at 1,000 ug/ml. Anti-bacterial effect was tested by disc diffusion method, and plant extracts showed mild anti-bacterial effect for normal skin flora, Staphylococcus epidermidis while it indicated strong anti-bacterial effect for acne inducing Propionibacterium acne. Therefore it had powerful potential for anti-acne material because of selectivity. Anti-atopic dermatitis effect was tested by hairless mouse and plant extracts recovered damaged skin to near normal condition after 14 days of treatment. IgE concentration in treated mouse was decreased 16% compared with control. From the research, plant extracts indicated strong anti-acne and anti-atopic dermatitis effect, and showed strong potential for cosmetics and skin related medicine.

      • 감시경보시스템 오경보율 최소화를 통한 통합운영 최적화 및 효율성 향상

        김기은(Ki-Eun Kim),채종욱(Jong-Wook Chae),정진순(Ji-Soon Jeong),최장건(Jang-Geon Choi),변일환(Ill Hwan Byun) 대한전기학회 2010 대한전기학회 학술대회 논문집 Vol.2010 No.7

        It is purposed to raise stability of integrated operation and optimize supervisory alarm system by frist, improving Jeon-buk integrated operation-supervisory alarm system for prompt recognition and counter measure of accident. second, decreasing occurence of integratedd operation alarm through minimizing rate of false alarm.

      • KCI등재

        일부 성인의 구취와 구강건조감 및 스트레스의 관련성

        김기은 ( Ki-eun Kim ),한지형 ( Ji-hyoung Han ) 한국치위생과학회 2016 치위생과학회지 Vol.16 No.5

        본 연구는 을지대학교 치위생학과에 방문한 스케일링 환자 155명을 대상으로 구취와 구강건조감, 스트레스의 관련성을 파악하여 효율적인 구취관리를 위한 기초자료로 제공하고자 실시하였다. 분석은 PASW Statistics 18.0을 이용하였으며, 다음과 같은 결론을 얻었다. 일반적 특성에 따른 구취 측정 결과는 H2S의 경우 연령에 따라 유의한 차이가 있었으며, 20대가 355.61로 가장 높았고, 다음 50대가 227.85였다(p<0.001). CH3SH가 축농증, 비염이 있는 경우 높게 나타났다(p=0.034). 구취성분 간의 상관관계는 H₂S와 (CH₃)₂S가 관련성을 보였으며(r=0.492, p<0.01), 구취에 영향을 미치는 요인으로는 스트레스가 증가할수록 (CH₃)₂S 가 증가하는 것으로 나타났다. 이상의 결과 구취를 호소하는 환자 진단 시 스트레스와 같은 정서적 요인 조사에 좀 더 관심을 가지고 고려해야 할 필요가 있다고 생각되며, 체계 적이고 표준화된 진단 도구 개발에 노력해야 할 것이다. This study is conducted to provide a basis for effective management of bad breath with a poll in 155-scaling patients visiting the dental hygiene department of a university located in Gyeong-gi province after grasping the relevance among halitosis, xerostomia, and stress from them. Analysis was performed using PASW Statistics 18.0. The results of the halitosis measurements based on the general properties showed a significant difference in the hydrogen sulfide (H₂S) level depending on the patient’s age; the highest level of 355.61 was observed in patients in their twenties followed by 227.85 in the fifties (p<0.001). The level was higher in cases with sinusitis or rhinitis (p=0.034). The H2S and (CH₃)₂S levels showed are levant (r=0.492, p<0.01) correlation with the components of halitosis. Further, among other factors affecting breath odor, (CH₃)₂S was shown to increase with increased stress. These results indicate that emotional factors, such as stress, should be considered when diagnosing patients with halitosis, and systematic and standardized diagnostic tools should be developed.

      • KCI등재

        칫솔질 교육 후 치면세균막 지수와 수행도의 변화

        김기은 ( Ki Eun Kim ),안은숙 ( Eun Suk Ahn ),한지형 ( Ji Hyoung Han ) 한국치위생과학회 2015 치위생과학회지 Vol.15 No.2

        This study was conducted to examine O`leary index, patient hygiene performance (PHP) index, and toothbrushing practice assessment in subjects of college students in 20s who had been randomly selected. The purpose of this study is to examine if it is easy for rolling method which is recommended by many dental professionals in Korea to implement and to effectively remove dental plaque. Also, the correlations between dental plaque index and toothbrushing practice assessment with the course of time was confirmed, after instruction session on toothbrushing was provided. STATA 11.0 (StataCorp) was used for analysis. There was no significant difference on the three ways of O`leary index, PHP index, and toothbrushing practice assessment in using rolling method, bass technique and toothpick method when comparing the average resulting from first to third instruction session on toothbrushing. O`leary index, PHP index, and toothbrushing practice assessment were inspected with Kruskal-Wallis test which is used for non-parametric statistics. They were checked three times: the first, before the toothbrushing instruction was given; the second, two weeks after the toothbrushing session was given; and the third, 4 weeks after the session. The results are as follows: O`leary index stood at the lowest in the first experiment but showed the highest in the second (p=0.0001). PHP index was the highest level in the first trial and decreased in the second time, but increased again in the last examination (p=0.0001). Toothbrushing practice assessment also showed a similar tendency with PHP index (p=0.0001). In conclusion, rolling method is not the best option for everyone, and it is thought that more various toothbrushing ways need to be reviewed and recommended to people. Also, institutional framework is required for the continuous education on toothbrushing to be in place as the effectiveness of the education is decreased with time.

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