식방풍의 혈관성 치매에 대한 예방과 치료효과 검증

김가나 ( Ka Na Kim ),최지민 ( Min Ji Choi ),이영혁 ( Young Hyurk Lee ),조성훈 ( Seung Hun Cho ) 대한한방신경정신과학회 2013 동의신경정신과학회지 Vol.24 No.1

Objectives: During several thousand years, Peucedanum Japonicum Thunberg has been considered as a vegetable side dish in Korea. There is folk knowledge that Peucedanum Japonicum Thunberg prevents vascular disease such as stroke. To identify the effects Peucedanum Japonicum Thunberg, we made up its extract and named it as KH020. Then, we employed common carotid artery ligation (CCAl) surgery for vascular dementia model (VDM), and two types doses of per os (per oral: p.o) treatment. Methods: To confirm prevention and recovery effects for vascular dementia, we treated two doses (100, 400 mg/kg) KH020 in male C57BL/6 mouse during 7 days. After treatment, animals were CCAl operated, and given time to recover. Then, animal were tested in a Y-maze and passive avoidance test. Results: Y-maze results demonstrated that cognition and memory performance were decreased in the VDM group, compared to the sham group. KH020 treatment abolished these effects significantly. The results from the passive avoidance test showed the same phenomenon, but it was not statically significant. Conclusions: Therefore, KH020 prevents the onset of vascular dementia. In future studies, we will evaluate KH020 in regard to alzheimer dementia.

혈관성 치매 치료 한약물 임상연구 고찰

김가나 ( Ka Na Kim ),조성훈 ( Seung Hun Cho ) 대한한방신경정신과학회 2012 동의신경정신과학회지 Vol.23 No.4

노인성우울증에 대한 한방 집중치료 프로그램의 효과

김가나 ( Ka Na Kim ),황의완 ( Wei Wan Hwang ),조성훈 ( Seung Hun Cho ) 대한한방신경정신과학회 2014 동의신경정신과학회지 Vol.25 No.4

Objectives: As the elderly population grows and the prevalence of depression increases, the incidence of geriatric depression disorder will continue to increase. The effect of an intensive Korean medicine treatment program on geriatric depression disorder was studied. Methods: Geriatric depression disorder patients who received treatment over a period of three years were reviewed, with the geriatric depression score (GDS) used as the primary outcome. The intensive Korean medical treatment program applied to the geriatric depression disorder patients consisted of herbal medicine, acupuncture, pharmacopuncture, moxibustion, meditation, qigong exercises, and reminiscence therapy. Results: The GDS scores of patients who received the intensive Korean medical treatment program decreased from an average of 19.57 (±5.52) to 15.76 (±6.99) and there was a significant difference. Conclusions: When the intensive Korean medical treatment program was applied to geriatric depression disorder patients, the symptoms of depression improved. This treatment program will be helpful for improving symptoms in patients and can be applied by trained clinicians.

치매 한의진단 평가도구 적용 연구

김가나 ( Ka Na Kim ),배현수 ( Hyun Su Bae ),황의완 ( Wei Wan Hwang ),조성훈 ( Seung Hun Cho ) 대한한방신경정신과학회 2014 동의신경정신과학회지 Vol.25 No.4

Objectives: Patients with dementia are increasing in Korea. So the importance of accurate diagnosis and treatment of dementia is growing. In this paper, we evaluated the result of employing the Korean medical diagnostic pattern as a tool in clinics. Methods: Patients diagnosed with Alzheimer`s disease were evaluated using the Korean medical diagnostic pattern tool. Results: The number of patients with liver-kidney yin deficiency pattern/syndrome was 35. Analyzing the ratio difference between the ``liver-kidney yin deficiency`` group and the ``not liver-kidney yin deficiency`` group revealed that the ratio of the responses to the fourth question was less than zero. The ratio of the responses to the fifth, seventh, and eight questions were all less than 10%. The ratio of the responses to the first and second questions were greater than 30%. Conclusions: Of the six diagnostic patterns, liver-kidney yin deficiency was the greatest in the study subjects. The fourth question in the liver-kidney yin deficiency tool tests for the lack of appropriateness whereas the fifth, seventh, and eight questions test for lack of discrimination. Applying more weight to the first and second questions was an excellent choice to increase the discrimination.

분노증후군과 주요우울장애의 뇌파 연구

김가나,최민지,지상은,조성훈,Kim, Ka-Na,Choi, Min-Ji,Ji, Sang-Eun,Cho, Seung-Hun 대한한방신경정신과학회 2013 동의신경정신과학회지 Vol.24 No.suppl1

Objectives : We will discuss the differences on EEG results of Post-traumatic embitterment disorder (PTED) and Major depressive disorder (MDD). Methods : We measured EEG on 21 sites (Fp1, Fpz, Fp2, F7, F3, Fz, F4, F8, T3, C3, Cz, C4, T4, T5, P3, Pz, P4, T6, O1, Oz, O2) of PTED and MDD. Then, we compared the results. Results : There is a significant result of a beta band between PTED and MDD. Conclusions : We became aware of the differences on EEG results of PTED and MDD. This can be used as the basis of diagnosis.

근골격계 질환의 수기요법에 관한 경제성 평가 : 체계적 문헌 고찰 및 근거 합성 연구

김창곤(Chang-Gon Kim),이진현(Jin-Hyun Lee),김가나(Ka-Na Kim),신병철(Byung-Cheul Shin),고연석(Youn-Suk Ko),박태용(Tae-Yong Park),하원배(Won-Bae Ha),이정한(Jung-Han Lee) 척추신경추나의학회 2020 척추신경추나의학회지 Vol.15 No.1

연구 목적 : 본 연구는 근골격계 질환에 대한 수기치료가 갖는 경제적 효과를 체계적으로 평가해 보기 위해 시행되었다. 연구 방법 : 2017년 2월 2일까지 국내외 관련 문헌을 체계적으로 검색 하였으며, 연관된 체계적 고찰 논문의 참고문헌을 조사하였다. 두 명의 연구자가 독립적으로 문헌을 선택하고, 비뚤림 위험 평가 및 경제성 평가 질 평가, 자료 추출을 시행하였다. 연구 결과 : 총 3,327개의 논문을 검토하여 최종적으로 18개의 무작위 대조 연구가 포함되었다. 경제성 평가는 수기요법과 다른 치료방법간의 유효성 비교를 통해 시행되었다. 요부 통증, 견관절 통증 및 외측 상과염 치료에 있어 침치료, 견인치료, 주사치료, 일반의 치료, 척추 안정화 기법 및 통증관리 치료보다 비용 효과적인 것으로 나타났다. 또한 또한, 수기치료는 경항통, 흉통, 고관절염 혹은 슬관절염, 경추신경병증 및 수부손상 치료에 있어 일반적 치료, 물리치료, 자가 치료 프로그램, 견인 치료에 비하여 효과적인 치료인 것으로 확인되었다. 결론 : 18개의 논문 중 10개의 논문에서 근골격계 질환 치료에 있어 수기치료가 경제적으로 효과가 있는 것으로 나타났다. 이러한 결과는 다른 치료방법에 비해 수기요법이 근골격계 질환에 있어서 경제적 가치가 있음을 시사하는 내용이다. 하지만, 근골격계 질환 수기치료의 경제성 평가에 대한 선행 연구는 전반적으로 부족한 실정으로, 보다 정확한 결과를 제시하고 정책결정을 위한 효과적인 제안을 위해서는 체계적인 추가 연구가 필요하다 사료되는 바이다.

한의병증에 대한 신경정신과적 증상 기술 연구

장재순 ( Jae-soon Jang ),김가나 ( Ka-na Kim ),조성훈 ( Seung-hun Cho ) 대한한방신경정신과학회 2016 동의신경정신과학회지 Vol.27 No.4

Objectives: This study aimed to develop a standard understanding of neuropsychiatric symptoms and signs of Disease Pattern Identification/syndrome in Korean Medicine. Methods: We investigated various published articles, and the proposals are based on a comparative analysis between Korean medicine literature and DSM5, ICD-10. To improve our understanding, we engaged in a consultation through discussions with the advisory committee. Results: We describe the physical and neuropsychiatric symptoms in a modern sense of the major dis-ease Pattern in Korean Medicine. We also proposed a profound understanding of the neuropsychiatric symptoms and signs of Disease Pattern Identification/syndrome in Korean Medicine. Conclusions: Compared with DSM5, ICD-10, the system of neuropsychiatric diagnosis in Korean medi-cine, could be profoundly organized into a system in a modern sense. It would be helpful to apply this understanding to clinical practices. There are several points of consideration in this study. The system of neuropsychiatric diagnosis in Korean medicine cannot be a perfect match for DSM5 or ICD-10. In addition, we could not reach a complete consensus on the disease pattern. Although there are some limitations to this study, it is meaningful to have an understanding of the neuropsychiatric symptoms and signs in Korean medicine through discussions with the advisory committee. This trial is expected to be applicable to related research in the future.

LPGA 선수 이미지가 스폰서 기업 브랜드 이미지 및 소비자 구매행동에 미치는 영향

신진호(Jin Ho Shin),구본수(Bon Soo Koo),김가나(Ka Na Kim),김차용(Cha Yong Kim) 한국사회체육학회 2013 한국사회체육학회지 Vol.0 No.53

The purpose of this study was to examine the effect of player image of LPGA on corporate brand image of sponsorship and consumer`s purchasing behavior. The 600 consumers of golf wear were chosen from 4 areas of located in Seoul, Gyeonggi-do, Chungcheongnam-do and Chungcheongbuk-do. Among 600 questionnaires distributed and collected, 181 were excluded from the study because they were neither thoughtfully nor completely answered. For the purpose of this study, frequency analysis, exploratory factor analysis, reliability analysis, confirmatory factor analysis, structural equation model analysis of SPSS 20.0 and AMOS 20.0 were performed. The research results of this study indicate that First. player image of LPGA had a significant influence on corporate brand image of sponsorship. Second, corporate brand image of sponsorship had a significant influence on consumer`s purchasing behavior. Finally, player image of LPGA had not a significant influence on consumer`s purchasing behavior.