요관 세척 세포학적 검사로 진단된 요관 아밀로이드증 - 1 예 보고 -

이원애,기정혜,진윤미,이미경,Lee, Won-Ae,Kie, Jeong-Hae,Jeen, Yoon-Mi,Lee, Mi-Kyung 대한세포병리학회 2002 대한세포병리학회지 Vol.13 No.1

Localized amyloidosis of the ureter is rare and clinically confused with neoplasm. We describe a case of localized amyloidosis of the ureter in which the presence of amyloid was detected in ureteral washing cytology. A 75-year-old female presented with gross hematuria. Abdominal CT and retrograde pyelography revealed hydronephrosis and hydroureter on the left side with abrupt narrowing of the distal ureter. Ureteral washing cytology yielded a hypocellular smear with many irregular clumps of amorphous, extracellar, waxy material. Biopsy sections demonstrated submucosal deposits of eosinophilic amorphous material which gave characteristic apple green birefringence with Congo-red stain under the polarized light. Familarity with the cytologic features of amyloid is helpful for preoperative diagnosis and proper treatment.

위눈꺼풀에 발생한 원발성 기타 상세불명의 말초 T세포 림프종 1예

노시진,기정혜,김혜영,Si Jin Noh,Jeong Hae Kie,Hye Young Kim 대한안과학회 2012 대한안과학회지 Vol.53 No.11

Purpose: To report a case of primary peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS), of the eyelid. Methods: A 48-year-old healthy male patient presented with a mass on the upper lid of 2 months in duration. The lesion was reddish, well - demarcated, oval shaped, and measured approximately 8 × 4 mm. The mass did not respond to incisional drainage and intra-lesional triamcinolone. An excisional biopsy for diagnosis was performed. Results: On microscopic examination, a localized dense lymphocytic infiltration was observed in the subepithelial area, and cytologic atypia was observed under high power. On immunohistochemical examination, tumor cells were positive for CD3 but negative for CD20, CD30, CD56, ĸ-light chain immunoglobulin, λ-light chain immunoglobulin, and increased Ki-67 activity was noted. A histopathological diagnosis of PTCL-NOS was made. Conclusions: PTCL-NOS, which rarely occurs on the eyelids, commonly accompanies generalized lymphadenopathy and “B symptoms” such as fever and weight loss. Herein, the authors report a case of PTCL-NOS of the eyelid presenting as a rapidly growing solid mass in an otherwise healthy patient.

IgA 신병증에 합병된 신증후군의 자연관해를 보인 증례보고

김정호 ( Jeong Ho Kim ),김하나 ( Ha Na Kim ),홍석민 ( Seok Min Hong ),기정혜 ( Jeong Hae Kie ),강이화 ( Ea Wha Kang ),신석균 ( Suk Kyun Shin ),한승혁 ( Seung Hyeok Han ) 대한신장학회 2010 Kidney Research and Clinical Practice Vol.29 No.3

Although a moderate degree of proteinuria is common in patients with IgA nephropathy (IgAN), nephrotic syndrome combined with IgAN is rare. It has been reported that approximately 5% of all patients with IgAN are complicated by minimal change disease and these patients respond well to corticosteroid therapy. However, spontaneous remission is uncommon in heavy proteinuric patients with IgAN. Recently, we experienced two cases of spontaneous remission of nephrotic syndrome combined with IgAN without use of corticosteroid. In these patients, heavy proteinuria disappeared in 1 month after the onset and no recurrence occurred during follow-up. With such limited number of cases, factors associated with spontaneous remission in these patients could not be explored. Further study with a larger number of patients is required and careful attention should be paid to these complicated cases.

소두증을 동반한 조기 발현 신증후군 1례 : Galloway-Mowat 증후군

유병원,조성민,기정혜,정희정,김기혁,Yoo Byung-Won,Cho Sung-Min,Kie Jeong-Hae,Jung Hee-Jung,Kim Kee-Hyuck 대한소아신장학회 2003 Childhood kidney diseases Vol.7 No.2

The Galloway-Mowat syndrome, a rare inherited disorder, is characterized by congenital microcephaly with various neurological abnormalities and early onset of nephrotic syndrome with unresponsiveness to treatment, progressive deterioration in renal function and death in early lifetime. In this report, we describe a girl with microcephaly, seizures. and psychomotor retardation who developed nephrotic syndrome at 17 months of age. 다양한 신경학적 이상을 동반한 소두증과 조기발현 신증군을 보이는 Galloway-Mowat 증후군은 치료반응이 불량하며 신기능의 저하가 진행되 조기에 사망하는 드문 유전성 질환이다. 임상적, 조직학적 다양성을 보이는 소두증과 신증후군을 동반한 일련의 질환군에 대해 아직 그 견해가 정립되지 않았고 향후 지속적인 연구가 이어질 것으로 생각되며 유전성 및 예후 등을 고려할 때 주목해야 할 필요가 있다고 생각되어 저자들이 경험한 소두증과 신경학적 이상을 동반한 조기발현 신증후군 1례를 보고하는 바이다.

유두상 갑상선 암에 의한 흉막 전이 1예

정재헌 ( Jae Heon Jeong ),신상윤 ( Sang Yun Shin ),손명균 ( Myoung Kyun Son ),이영주 ( Young Joo Lee ),김세현 ( Se Hyun Kim ),기정혜 ( Jeong Hae Kie ),최윤정 ( Yoon Jung Choi ),홍용국 ( Yong Kook Hong ),한창훈 ( Chang Hoon Hahn 대한결핵 및 호흡기학회 2007 Tuberculosis and Respiratory Diseases Vol.63 No.2

악성 흉수의 원인은 폐암, 유방암, 및 악성 림프종, 백혈병이 그 대부분을 차지하며 내분비 종양에 의한 악성 흉수는 매우 드물며 특히 유두상 갑상선 암에 의한 흉수는 거의 없다. 저자들은 유두상 갑상선 암이 폐 전이를 거치지 않고 유방 전이를 거쳐 흉막 전이 일으킨 것으로 보이는 1예를 경험하였기에 보고하는 바이다. 아울러 원인이 명확하지 않은 악성 흉수의 원인 감별에 유두상 갑상선 암도 고려 대상으로 할 필요가 있다고 생각한다. Lung cancer, breast cancer and lymphoma are the common oncologic causes of malignant pleural effusion, comprising more than the half of the causes. However, an endocrinologic carcinoma associated malignant effusion is very rare. Recently, we encountered a case of papillary thyroid carcinoma causing malignant effusion. An 83-year-old female patient presented with dyspnea due to massive pleural effusion in her left side. The pleural biopsy, pleural fluid cytology and breast needle aspiration biopsy results were consistent with a metastatic papillary thyroid carcinoma. Thyroid ultrasonography showed two thyroid masses, but the patient refused a thyroid biopsy. This case highlights the need for considering the possibility of papillary thyroid carcinoma when the cause of malignant pleural effusion cannot be found because one of the rare clinical manifestations of a papillary thyroid carcinoma can be dyspnea due to malignant effusion. (Tuberc Respir Dis 2007; 63: 188-193)

혀에 국한하여 발생한 대칭성 지방종증 1예

정세원(Se Won Jeong),남재성(Jae Sung Nam),기정혜(Jeong Hae Kie),신향애(Hyang Ae Shin) 대한두경부종양학회 2015 대한두경부 종양학회지 Vol.31 No.2

Benign symmetric lipomatosis, also known as Madelung’s disease, Launois–Bensaude syndrome and multiple sym-metric lipomatosis is a cutaneous condition characterized by extensive symmetric fat deposits in the neck, shoulders, and upper trunk. But symmetrical lipomatosis of the tongue is very rare and characterized by involvement exclusively of the tongue, invasiveness, and absence of encapsulation of the adipose tissue. A 75-year-old man presented with about a year history of painless tongue masses on both lateral border. Bilateral partial glossectomy was performed and subsequently was confirmed as symmetrical lipomatosis pathologically. We report this case with a review of the literatures.

상완에 발생한 고립성 고대 신경초종: 증례 보고

이윤태,김철,박상훈,기정혜,Lee, Yun-Tae,Kim, Chul,Park, Sang-Hoon,Kie, Jeong Hae 대한근골격종양학회 2013 대한골관절종양학회지 Vol.19 No.1

고대 신경초종(ancient schwannoma)은 신경초종의 변이(variant)로서 천천히 자라나고 퇴행성 변화를 동반한 양성종양으로 알려져 있다. 또한 신경초종은 신전부에서는 상대적으로 드물게 발생하는 것으로 보고되어 왔다. 저자들은 50세 남자 환자의 상완 신전부 삼두근에서 발생한 고립성 고대 신경초종을 경험하였기에 이를 보고하고자 하였다. Ancient schwannoma is a variant of schwannoma and is characterized slowly growing tumor with degenerative change. And it is reported that schwannoma is relatively rare in extensor area. As a rare cause of solitary ancient schwannoma in extensor area of upper arm, we report it.

경부에 발생한 점액성 지방육종 1예

이규인(Kyuin Lee),기정혜(Jeong Hae Kie),신향애(Hyang-Ae Shin),김지훈(Ji-Hoon Kim) 대한두경부종양학회 2021 대한두경부 종양학회지 Vol.37 No.2

Liposarcoma is a very rare malignant tumor affecting the head and neck area. Since it is an invasive and lifethreatening disease, active treatments is necessary. However, differential it from lipoma, its corresponding benign counterpart, may be difficult. Herein, we report a rare case of posterior neck myxoid liposarcoma in a 72-year-old man who was initially misdiagnosed with lipoma, including a literature review of differential diagnosis between lipoma and liposarcoma.

양측 안와종괴로 발현한 안와결핵 1예

안현민(Hyun Min Ahn),기정혜(Jeong Hae Kie),김혜영(Hye Young Kim) 대한안과학회 2017 대한안과학회지 Vol.58 No.7

목적: 안과 영역에서 결핵은 결막결절이나 포도막염 형태로 흔히 나타나며 안와의 감염은 매우 드물다. 저자들은 양측 안와에 발생한 종괴에서 결핵을 진단하여 이를 보고하고자 한다. 증례요약: 64세 남성이 복시를 주소로 내원하였다. 과거력상 당뇨와 고혈압, 만성폐쇄성폐질환의 병력이 있었다. 양안의 교정시력은 1.0, 안압은 16 mmHg였으며, 양안에 안구돌출이 있었고, 양안 모두 하측 안와에서 종괴가 촉진되었다. 안와 컴퓨터단층촬영상, 근원추 바깥쪽에서 안구를 전체적으로 불규칙하게 둘러싸는 경계가 불명확한 종괴가 양안 모두에서 관찰되었다. 국소마취하에 양안에서 종양의 절개생검을 시행하였으며 병리조직검사상 건락괴사가 동반된 만성 육아종성 염증이 관찰되어 양안 안와 결핵으로 진단하였다. 호흡기내과에 전원하여 Isonizid, Rifampin, Ethambutol 3제 요법으로 치료를 12개월간 유지하여 종괴는 완전히 소실되었으며 치료 종료 12개월 후까지 재발이나 합병증은 없었다. 결론: 양안 안와에 발생한 종괴에서 결핵을 진단하고 치료하였으며 안와 결핵은 국내에 보고된 바 없기에 이를 보고하는 바이다. <대한안과학회지 2017;58(7):862-865> Purpose: Periocular tuberculosis is common in the form of conjunctival tuberculosis or uveitis; however, orbital tuberculosis is very rare. We report a case of tuberculosis diagnosed based on bilateral orbital masses. Case summary: A 64-year-old male with a history of diabetes, hypertension, and chronic obstructive pulmonary disease presented with diplopia. His best-corrected visual acuity was 1.0, and intraocular pressure was 16 mmHg in both eyes. Bilateral proptosis was noted, and inferior orbital masses were palpated in both eyes. On orbital computed tomography, irregular masses were surrounding both globes in the extraconal space. Incisional biopsy of the bilateral orbital masses was performed under local anesthesia. Pathologic examination revealed chronic granulomatous inflammation accompanied by caseous necrosis. The patient was diagnosed with bilateral orbital tuberculosis and underwent triple therapy with isoniazid, rifampin, and ethambutol for 12 months. The orbital masses completely resolved, and there was no recurrence or complication through 12 months after treatment. Conclusions: To our knowledge, bilateral orbital tuberculosis has not been reported yet. Herein, we report a case of orbital tuberculosis presenting as bilateral orbital masses. J Korean Ophthalmol Soc 2017;58(7):862-865

급성 A형 간염 환자에서 동반된 IgA 신병증 1예

홍석민 ( Seok Min Hong ),박정경 ( Jeong Kyung Park ),김정호 ( Jeong Ho Kim ),기정혜 ( Jeong Hae Kie ),박병규 ( Byung Kyu Park ),강이화 ( Ea Wha Kang ),신석균 ( Suk Kyun Shin ),한승혁 ( Seung Hyeok Han ) 대한신장학회 2010 Kidney Research and Clinical Practice Vol.29 No.1

IgA nephropathy is the most common type of glomerulonephritis worldwide. Although primary IgA nephropathy receives the most attention, many other diseases are also associated with IgA nephropathy. Among these, chronic liver diseases such as alcoholic liver disease or hepatitis B or C have been reported as secondary causes of glomerular IgA deposits. Recently, as the prevalence of hepatitis A virus (HAV) infection is increasing in Korea, HAV-associated renal diseases occur frequently. Acute kidney injury (AKI) is one of the most common complications of HAV infection, mainly due to acute tubular necrosis or interstitial nephritis. However, unlike hepatitis B and C, glomerular involvement is extremely rare in acute HAV infection. Here, we report a case of biopsy-proven IgA nephropathy with serologically documented HAV infection. The patient presented moderate degree of proteinuria without evidence of AKI. Renal biopsy revealed mesangial IgA deposits but tubular or interstitial inflammation was not observed. This report suggests that HAV infection may be a secondary cause of IgA nephropathy. However, further studies are required to elucidate a causal link between hepatitis A and mesangial IgA deposits.