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Total antioxidant status (TAS) 참고치 및 고콜레스테롤혈증, 당뇨병과의 관련성에 관한 연구
권영일 ( Young Il Kwon ),서은주 ( Eun Ju Seo ),홍효선 ( Hyo Sun Hong ),안희은 ( Hee Eun Ahn ),박찬호 ( Chan Ho Park ),노명희 ( Myung Hee Rho ) 대한임상검사과학회 1999 대한임상검사과학회지(KJCLS) Vol.31 No.2
Introduction : The Object of this study is to investigate the reference ranges of total antioxidant status(TAS) according to age and sex in korea. The human body is constantly under attack from free radicals. Free radica1s are highly reactive molecules and once formed, attack cell structures with the body. As a resu1t, free radicals have been implicated in numerous disease. In hea1thy individua1s, the antioxidant system defends tissues against free radica1 attack. Methods and materials : We measured the tota1 antioxidant status of 90 norma1 group, 30 diabetes group and 30 hypercholesterolemia group. (The each group sex ratio : ha1f to ha1ij For each test, age and sex related variations were assessed and reference values were estimated for three different age groups.(below 20, 21-40, above 41) TAS measured by Randox Tota1 Antioxidant reagent and Hitachi 7150. Results : ’fhe reference va1ues according to age were 0.930- 1.332mmolfL in below 20 years of age, 1.007 -1.391mmolfL in 21-40 years of age and 0.995- 1.295mmolfL inabove 41 year of age and showed statistica11y significant difference.(P<0.05) The Reference ranges of tota1 age group, ma1e and fema1e group were 0.991- 1.343mmolfL, 1.038- 1.370mmolfL, and 0.977 -1.285mmolfL respectively. Between the ma1e and fema1e group were statistically signficant difference.(P<0.05) The TAS means of diabetes and hypercholesterolemia were 1.26mmoljL and 1.23mmoljL respectively. TAS values of hypercholerterolemia an normal group were no significant difference whereas diabetes and normal group were significant difference.(P<O.OOl) Conclusions : We established that reference ranges were analyzed age and sex related variations for total antioxidant status. Between experimental groups showed generally significant differences. In the future, correct diagnosis of disease induced free radicals need to measure total antioxidant level and each antioxidants.
권영일(Kwon, Young Il) 한국신뢰성학회 2010 신뢰성응용연구 Vol.10 No.1
In general, the performance of a component degrades as time goes by and failure of a component occurs when the performance degradation reaches a pre-specified level. It is difficult to obtain the failure time distribution data or the necessary number of failure data especially for the metal or machine part. Thus, a design of reliability qualification test based on performance distribution is more effective than failure time distribution. In this study, a performance-based reliability qualification test is developed and a numerical example is provided to illustrate the use of the developed reliability qualification test. This approach could be applied to many kinds of metal or machine part whose magnitude of strength could not be evaluated during at any random points but judgement can be made by only failure of the part. Besides, it is also possible that any parts which have a similar failure characteristics could be applicable to the developed reliability qualification test.
권영일(Kwon, Young Il) 한국신뢰성학회 2013 신뢰성응용연구 Vol.13 No.1
A Bayesian zero-failure reliability demonstration test method for products with exponential lifetime distribution is presented. Beta prior distribution for reliability of a product is used to design the Bayesian test plan and selecting a prior distribution using a prior test information is discussed. A test procedure with zero-failure acceptance criterion is developed that guarantees specified reliability of a product with given confidence level. An example is provided to illustrate the use of the developed Bayesian reliability demonstration test method.
가속열화시험에 의한 콘크리트용 탄소섬유 강화플라스틱 바의 사용수명 예측
권영일(Young Il Kwon),김승진(Seung Jin Kim),이형욱(Hyoung Wook Lee) 한국신뢰성학회 2009 신뢰성응용연구 Vol.9 No.2
This paper discusses the service life prediction methods for CFRP bar for concrete reinforcement using accelerated degradation tests. The relationship between performance degradation and the rate of a failure-causing chemical reaction is assumed for the temperature accelerated degradation tests. Methods of obtaining acceleration factors and predicting service life of the CFRP bar using the degradation model are presented.