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Systemic therapy로 부분 반응 이상의 치료 반응을 보인 간세포암종 환장 증례 : 간동맥내 항암약물 주입요법으로 부분 반응 이상의 치료 반응을 보인 간세포암종 환자 1예
박창욱 ( Chang Wook Park ),권영란 ( Young Lan Kwon ),김용진 ( Yong Jin Kim ),김윤정 ( Yoon Jung Kim ),서혜진 ( Hye Jin Seo ),이경인 ( Kyung In Lee ),김은수 ( Eun Soo Kim ),장병국 ( Byung Kook Jang ),정우진 ( Woo Jin Jeong ),박경식 대한간암연구회 2010 대한간암학회지 Vol.10 No.-
Hepatocellular carcinoma (HCC) is one of the cancers with poor prognosis. Especially potal vein invasion is a grave prognostic indicator in the setting of HCC. There is currently no effective method for treatment of HCC with portal vein invasion. A 61-year-old female patient was diagnosed a massive HCCs in both hepatic lobe with portal vein thrombosis, based on computed tomography (CT) and increased tumor marker, α-fetoprotein. She was treated with intrahepatic arterial CDDP (10 mg on 1~5 day), 5-FU (250mg on 1~5 day) and leukovorin (12mg on 1~5 day) infusion via percutaneously implantable port system (PIPS) every 3 weeks, totally seven times. The patient was still living 6 months after first hepatic arterial infusion chemotherapy (HAIC) and follow-up CT showed partial response with necrosis of HCCs. We report here a case of advanced HCC with portal vein thrombosis that was effectively treated with HAIC via PIPS.
간외 전이로 처음 발견된 간세포암종 늑골 전이로 발현된 간세포암종
이경인 ( Kyung In Lee ),권영란 ( Young Lan Kwon ),김윤정 ( Yoon Jung Kim ),서혜진 ( Hye Jin Seo ),김용진 ( Yong Jin Kim ),박창욱 ( Chang Wook Park ),김은수 ( Eun Soo Kim ),장병국 ( Byoung Kuk Jang ),정우진 ( Woo Jin Chung ),박경식 대한간암학회 2010 대한간암학회지 Vol.10 No.-
Bone metastasis is not uncommon and shows poor survival in patients with hepatocellular carcinoma (HCC). We describe a case of HCC presenting with rib metastasis in a 54-year-old man. In spite of radiotherapy for rib metastasis, pain was sustained and size of lesions were increased. So we performd CT-guided percutaneous ethanol injection therapy (PEIT). Whenever new metastatic bone lesions were detected, we have done PEIT. However, abdominal CT scan at 25th month after diagnosis shows residual viable tumors in pelvic bone and multiple metastatic nodules in both lung. He is alive by taking conservative management for 27 months after diagnosis.