Capture-recapture 방법을 이용한 광주광역시 지역암등록 자료의 완전성 추정

권순석,김상용,박경수,손석준,최진수,임정수,Kweon, Sun-Seog,Kim, Sang-Yong,Park, Kyeong-Soo,Sohn, Seok-Joon,Choi, Jin-Su,Im, Jeong-Soo 대한예방의학회 2000 예방의학회지 Vol.33 No.1

Objectives : This study aimed to estimate the completeness of cancer registration with Capture-recapture method. Methods : The study was conducted in the population based cancer registry of Kwangju, Korea, for which there are three main sources of notification: reports by Korean Central Cancer Registry, reports by pathology data, and the others reports by radiology data, death certificates, etc. The defined cases in three sources were matched by 13 digits Resident Register Number. To derive an estimates, log-linear models were applicated. Results : Overall completeness was estimated to be around 93%. There was some variation with age(consistently high levels below age group 60-74 years, a minimum of 88.6% above 75 years). Among the most common cancer sites, estimates of completeness were highest for thyroid cancer(97.1%), while lower estimates of completeness were derived for stomach cancer(92.3%), liver cancer(92.6%). Conclusions : Careful application of Capture-recapture method may provide an alternative to traditional approaches for estimating the completeness of cancer registration in Kwangju city.

지역사회 건강한 성인에서 알코올 섭취량 및 폭음과 동맥경직도의 관련성

권순석(Sun-Seog Kweon),이영훈(Young-Hoon Lee) 한국농촌의학 지역보건학회 2012 농촌의학·지역보건 Vol.37 No.1

지역사회 성인을 대상으로 알코올 섭취량과 동맥경직도의 관련성을 파악하였으며, 아울러 폭음과 동맥경직도의 관련성을 살펴보았다. 지역사회기반 코호트 연구에 참여한 50세 이상 성인 5944명을 대상으로 하루 평균 알코올 소비량(g/day)과 월 폭음 빈도를 조사하였다. 상완-발목동맥 맥파전도속도(baPWV)를 측정한 후 남녀 각각에서 baPWV 4사분위에 해당하는 집단을 ‘high baPWV’로 정의하였다. 남성 알코올 섭취군의 교차비는 비음주군과 비교해서 유의한 차이가 없었지만, >40.0 g/d 알코올섭취군의 교차비는 유의하게 증가하였다. 모든 여성 알코올 섭취군의 교차비는 비음주군에 비해서 유의한 차이가 없었다. 남성에서는 비폭음군에 비해 주 1회 미만 폭음군 및 주 1회 이상 폭음군의 high baPWV에 대한 교차비가 유의하게 증가하였다. 여성에서는 비폭음군에 비해 주 1회 이상 폭음군의 교차비가 유의하게 증가하였다. 남녀 모두에서 적당한 음주는 동맥경직도의 위험성이 낮은 반면, 과도한 음주는 동맥경직도의 위험성이 증가하였으며, 전반적으로 알코올 섭취량과 baPWV로 측정한 동맥경직도 사이에는 J자 형태의 관련성이 있었다. 또한 알코올 섭취량을 포함한 기존의 심혈관 위험요인과는 독립적으로 남녀 모두에서 폭음이 동맥경직도와 유의한 관련성이 있었다. Objectives: The purpose of this study was to investigate the association of the average volume of alcohol consumption and binge drinking with arterial stiffness. Methods: The study population consisted of 5944 community-dwelling healthy adults aged 50 years and older. Average volume of alcohol consumption was calculated and frequency of binge drinking defined as the consumption of 7 or more drinks for men and 5 or more for women on a single occasion, was assessed using a structured interview. High brachial-ankle pulse wave velocity (baPWV), a marker of arterial stiffness, was defined as the highest gender-specific quartile of maximal baPWV distribution in the study population. Results: Compared to never drinkers, the multivariate-adjusted odds ratio (OR) of men who consumed 0.1-10.0, 10.1-20.0, 20.1-40.0, and >40.0 g/day was 0.93, 1.18, 1.38, and 2.36, respectively. The OR was 0.90, 0.97, 1.45, and 1.82 in women consuming 0.1-5.0, 5.1-10.0, 10.1-20.0, and >20.0 g/day, respectively. Binge drinking of <1 day/week (OR=1.66, 95% confidence interval [CI]=1.13-2.42) and ≥1 day/week (OR=1.61, 95% CI=1.04-2.50) were associated with increased risk for high baPWV in men, and binge drinking of ≥1 day/week (OR=3.12, 95% CI=1.16-8.34) was associated with increased risk for high baPWV in women. Conclusions: A J-shaped relationship between the average volume of alcohol consumption and high baPWV was observed, suggesting the detrimental effects of heavy alcohol drinking on arterial stiffness. Binge drinking was also significant risk factors for increased arterial stiffness, independently of the average volume of alcohol consumption.

A일개 군지역 암등록자료의 국민건강보험 보장유무에 따른 암 생존율 차이

권순석 ( Sun Seog Kweon ),이영훈 ( Young Hoon Lee ),최진수 ( Jin Su Choi ),신민호 ( Min Ho Shin ),김혜연 ( Hye Yeon Kim ),최성우 ( Seong Woo Choi ) 한국보건행정학회 2009 보건행정학회지 Vol.19 No.2

HCV epidemiology in Korea: Focused on community based HCV epidemiological investigation at Jindo-gun

권순석 ( Sun-seog Kweon ),조성범 ( Sung-bum Cho ) 대한간학회 2016 간학회 싱글토픽 심포지움 Vol.2016 No.1

Hepatitis C virus (HCV) is not endemic to South Korea, its seroprevalence is generally about 1%. Recently, an hepatocellular carcinoma(HCC) epidemic involving an island community resulted in a age-standardized incidence ratios based on Korean national data of 2.2 (95% confidence interval [CI] 1.9-2.5) and 2.2 (95% CI 1.8-2.7) in males and females, respectively, was noted between 1999 and 2008. To identify the cause of the high HCC rate, we conducted serologic surveys for hepatitis in study and control areas involving 2,068 and 2,950 residents (age ≥20 years), respectively, who had been sampled randomly in a previous community survey. We found an approximately four-fold higher HCV seroprevalence in the study area (5.5% vs. 1.3%). No significant difference in HBV was seen. A difference in the exposure to acupuncture was also identified. Ecological data suggest that the excessive HCC burden in the study community was closely associated with an HCV epidemic. Frequent exposure to acupuncture might be a risk factor in the HCV epidemic in this community.

일개 광역시의 지역사회단위 전염병감시체계의 운영 사례

권순석(Sun-Seog Kweon),박형철(Hyung-Cheol Park),남현(Hyun Nam),최진수(Jin-Su Choi) 한국역학회 2008 Epidemiology and Health Vol.30 No.2

Objectives: The surveillance of infectious diseases, which is crucial in public health, may also suffer from poor community support. In South Korea, the government operates several national surveillance system for the National notifiable infectious diseases(NNID). Some programs work satisfactorily but other programs may not be fully accepted at the community level which result in low participation and delayed report. Methods: May 2003, to improve the blind side of the National Surveillance System, a district health agency initiated a community based surveillance system for infectious diseases called as Communicable Disease Information Sharing System (CDISS) to complement the national program. As the name suggests, it underscores the mutual benefit of surveillance for public and private health sectors through partnership. With collaboration of participating private clinics and hospitals around the district, the health agency collects data and provides the health practitioners more up-to-dated information on the trend of infectious diseases than National level information. Total population of study area, Dong-gu which locate in the center of Gwangju-metropolitan city, is about 120,000 in 2005. Reporting facilities consist of 6 daycare clinics, 3 hospitals, and 1 university hospital, 2 local public health organizations. Results: CDISS was introduced in May 2003, and full system has been successfully operated since March 2004 with 10 participating facilities. Each reporting facility regularly sends the weekly reporting form, filled with the number of patients in last week, to Dong-gu District Health Center in every Wednesday. All data were organized in tables and graphs by weekly summarizing the reporting data and interpreted information. Feedback is done to reporting facilities until Friday through faxes, email, website (http://kjdisweb.richis.org) at least a week earlier than National Surveillance System.If reported data exceeded epidemic alert level, the community warnings are issued through mass-media and other means of public communication.During the period of CDISS operation, some epidemic events and sporadic outbreak occurred in Dong-gu were detected well-earlier than the notification at national level, such as chickenpox, viral enteritis, and epidemic keratoconjunctivitis(EKC). Conclusions: The program has been functioning successfully with active community participation and revealed to be economic and effective way of disease surveillance in the community. Several episodes of disease epidemic were reported by the program well before the recognition of the epidemic at the national level. We suggest that the community surveillance program may well complement national surveillance system.

혈압 수준과 경동맥 내중막 두께 및 동맥경화반의 관련성

이영훈,권순석,최진수,이정애,최성우,류소연,신민호,Lee, Young-Hoon,Kweon, Sun-Seog,Choi, Jin-Su,Rhee, Jung-Ae,Choi, Sung-Woo,Ryu, So-Yeon,Shin, Min-Ho 대한예방의학회 2009 예방의학회지 Vol.42 No.5

Objectives : The aim of this study was to investigate the association of blood pressure levels with the common carotid artery intima-media thickness (CCA-IMT) and carotid plaques. Methods : Data were obtained from 2,635 subjects, aged 50 years and over, who participated in the Community Health Survey (a population-based, cross-sectional study) in Dong-gu, Gwangju city between 2007 and 2008. Participants were categorized into three groups according to blood pressure levels; normotensives (<120/80 mmHg), prehypertensives (120-139/80-89 mmHg), and hypertensives ($\geq$140/90 mmHg). Prehypertensives were further categorized as low prehypertensives (120-129/80-84 mmHg) and high prehypertensives (130-139/85-89 mmHg). Carotid intima-media thickness and plaques were evaluated with a high-resolution B-mode ultrasound. Statistical analyses were performed using chi-square test, ANOVA, and multiple logistic regression. Results : Prehypertensives had significantly greater maximal CCA-IMT values than normotensives, with a multivariate adjusted odds ratio of 1.78 (95% CI=1.36-2.32) for abnormal CCA-IMT (maximal CCA-IMT$\geq$1.0 mm), and 1.45 (95% CI=1.19-1.77) for carotid plaques. The multivariate adjusted odds ratio of low prehypertensives was 1.64 (95% CI=1.21-2.21) for abnormal CCA-IMT, and 1.30 (95% CI=1.04-1.63) for carotid plaques compared with normotensives. Subject with hypertension had higher frequency of abnormal CCA-IMT (odds ratio, 2.18; 95% CI=1.49-3.18), and carotid plaques (odds ratio, 1.98; 95% CI=1.46-2.67) compared with normotensives after adjustment for other cardiovascular risk factors. Conclusions : Our results indicate that there is a significant increase in the prevalence of carotid atherosclerosis in subjects with prehypertension (even in low prehypertensives) compared with normotensive subjects. Further studies are required to confirm the benefits and role of carotid ultrasonography in persons with prehypertension.

어린이 보호구역 내에서 발생한 6-14세 어린이들의 보행 중 교통사고에 대한 역학적 조사

신민호,권순석,Shin, Min-Ho,Kweon, Sun-Seog 대한예방의학회 2005 예방의학회지 Vol.38 No.2

Objectives: Pedestrian traffic injuries have been an important cause of childhood mortality and morbidity for decades. The aim of this study was to describe the epidemiological characteristics of child pedestrian traffic injuries that occurred during 2000 in one metropolitan city and its school-zones, and to determine the factors associated with those accidents. Methods: A cross-sectional study was performed in 2001. Police records were used to identify the cases of pedestrian injury. Children aged between 6 and 15 years, injured during road walking, were included in this study. A direct survey of the environmental factors within the school-zones in study area (n=116) was also performed. Self-administered questionnaires, via mail and telephone surveys, were used to assess the safety education programmes. The schools were divided into two groups according to the occurrence of pedestrian traffic injuries in their school-zone. Results: Pedestrian injuries (n=597) were found to account for 3.2% of all traffic injuries in the subject area. The epidemiological characteristics were not significantly different between genders. There were some significant risk factors within the environmental factors, such as local road (OR: 2.3, 95% CI=1.05-5.35), heavy traffic volume (OR: 2.2, 95% CI=1.00-5.04), poor visibility of speed-limit signs (OR: 2.8, 95% CI=1.25-6.42), no separation of pedestrian routes from cars (OR: 2.6, 95% CI=1.02-6.75) and barriers on the pedestrian routes (OR: 2.2, 95% CI=1.01-5.08). Only one factor, that of education in a safety-park (OR: 0.3, 95% CI=0.09-0.96), was significantly associated in the traffic and pedestrian safety education factors. Conclusion: Significant associations with pedestrian injury risk were identified in some of the modifiable environmental factors than in the educational factors.

혈중 감마지티피와 청소년 대사증후군과의 관련성

류소연 ( So Yeon Ryu ),권순석 ( Sun-seog Kweon ),신민호 ( Min-ho Shin ),박형철 ( Hyung-chul Park ) 한국모자보건학회 2008 한국모자보건학회지 Vol.12 No.1

Objectives : This study was performed to investigate the association between serum gamma- glutamyltransferase (GGT) and the metabolic syndrome (MS) in Korean adolescents. Methods : Data were obtained from 1,372 students aged 12~13y with normal liver functions of 7 middle schools in a district of Gwang-ju. Serum GGT, alanine aminotransferase (ALT), body mass index(BMI), waist circumference, blood pressure, fasting glucose and lipid profiles were measured. MS was defined by criteria analogous to ATP Ⅲ as ≥3 of the following: 1) fasting triglycerides ≥100 mg/dL, 2) HDL-cholesterol < 50 mg/dL, 3) fasting glucose ≥110 mg/dL, 4) waist circumference >75th percentile for age and gender, and 5) systolic blood pressure >90th percentile for gender, age, and height. GGT quartiles were formed in assessing the likelihood of MS in logistic regression models that controlled for confounders such as sex, overweight and serum ALT. Results : The prevalence of MS was 5.2% (5.6% for male and 4.9% for female). The MS and its components were significantly related to increased serum GGT level except for HDL-cholesterol and fasting glucose. After the adjustment for sex, overweight and serum alanine aminotransferase (ALT), the association with the MS was attenuated, but the OR for MS was 2.06 (95% Confidence Interval: 1.02~4.17) in the highest compared with the lowest quartile of serum GGT. Conclusions : This study shows that serum GGT level, even within its normal range, is associated with the MS in Korean adolescents.

대학병원 간호사의 병원낙상 예방활동 수행정도와 관련요인

박인자(Park In Ja),권순석(Kweon Sun Seog) 전남대학교 간호과학연구소 2017 Nursing and Health Issues(NHI) Vol.22 No.1

서론 연구 방법 연구 결과 논의 결론

자가건강인지도에 따른 3년간의 의료이용도와 사망위험 비교

김상용,임정수,손석준,최진수,권순석,Kim, Sang-Yong,Im, Jeong-Soo,Sohn, Seok-Joon,Choi, Jin-Su,Kweon, Sun-Seog 대한예방의학회 1999 Journal of Preventive Medicine and Public Health Vol.32 No.3

Objectives: This 3-year longitudinal study was conducted to evaluate the influence of self-rating health perception on health care utilization and all cause-death risk. Methods: The hypothesis was tested using a community-based samples, among which subjects 3,414 were interviewed in 1995, Self-rating health perception was assessed by single-item question. Three components of health care utilization amount(number of visits, number of medications, yearly health care expenses) per year were measured using medical insurance data during 3-year follow-up period among subjects in district health care insurance. There were 123 deaths from all causes among 3,085 subjects interviewed. Results: The results showed that those who had poor health perception revealed more increases in the amount of health care utilization than good health perception group (p<0.05). After adjusting for age and sex, the poor health perception group had higher death risk over 3 years than good health perception group(hazard ratio=1.88). but, after adjusting health care utility, supplementary, was not significant. Conclusion: These results suggest that self-rating health perception was associated with difference in health care utilization and all cause-death risk. 1995년 1월과 7월에 전라남도 일부 농촌지역에 거주하는 20세 이상의 주민 3,085명을 대상으로 자가건강인지도를 측정하였다. 이후 3년간의 지역의료보험 지불자료에서 나타난 의료이용도 및 해당 지역 행정관청의 사망신고 자료를 이용하여 사망여부를 파악하여, 이들 변수들과 자가건강인지도와의 관련성을 조사해본 결과, 다음과 같은 결과를 얻었다. 1) 지역의료보험 대상자 1,090명에서 자가건강인지도에 대한 설문을 실시하기 이전인 1994년의 의료이용량에 비해 이후 3년간의 의료이용량이 자가건강인지도 불량군에서 더 많았으며, 수진일과 투약일은 더 크게 증가하였다. 2) 조사대상자 3,085명중 3년간의 사망자는 123명으로 연령과 성별을 보정한 생존분석 결과, 자가건강인지도 불량군이 양호군에 비해 더 높은 사망위험도를 나타냈다. 94년 지역의료보험에 가입되었던 1,376명중 사망자는 72명, 연령과 성별, 그리고 94년도 의료이용량을 보정 한 생존분석 결과 유의한 차이는 보이지 않았다. 이상의 결과를 요약해 볼 때, 비교적 단기간의 비교를 통해서도 의료이용도와 사망은 자가건강인지도에 따라 차이가 발생함을 알 수 있다. 특히 기존에 같은 정도의 의료이용을 하는 사람 중에서도 자신을 건강하지 않게 생각하는 사람이 향후 의료이용량이 더 크게 증가할 것으로 예측되었다. 따라서 자가건강인지도의 측정은 향후 개인 및 지역사회집단의 의료이용도와 사망 등 건강상의 문제를 예측하는데 유용한 도구로 사용할 수 있을 것으로 생각된다.