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신남식,권수완,김양범,김방현,오상연,김대용,Shin, Nam-Sik,Kwon, Soo-Wahn,Kim, Yang-Beum,Kim, Bang-Hyun,Oh, Sang-Yeon,Kim, Dae-yong 대한수의학회 2002 大韓獸醫學會誌 Vol.42 No.3
A 17-year-old female tiger (Panthera tigris altica) was found dead after suffering from continuously growing mass at the right mammary gland area. At necropsy, a firm tan mass approximately 25 cm in diameter was noted at the ventral abdomen. The mass was not fixed to the adjacent tissue and mottled tan to red on cut sections. Chains of similar nodules ranging from 2 to 5 cm in diameter were also present along the right mammary glands region. Histologically, the neoplastic masses consisted of lobules that were filled with pleomorphic neoplastic cells and separated by fibrious conntective tissue. The neoplastic cells have hyperchromatic nuclei with prominent nucleolus and moderate amount of cytoplasm. The degree of mitosis was high. Multiple areas of necrosis, hemorrhage, mineralization and tumor emboli were also noted. Metastasis to the regional lymph nodes, lung, liver, spleen, kidney, and adrenal gland were observed. Based on the gross and histopathologic examinations, a diagnosis of lobular type metastatic mammary gland carcinoma was made.
호랑이에서 Ketamine HCl/Xylazine HCl의 병용마취효과
신남식,권수완,한덕환,Shin Nam-Sik,Kwon Soo-Wahn,Han Duk-Hwan 한국임상수의학회 1993 한국임상수의학회지 Vol.10 No.2
Combined intramuscular administration of ketamine 8mg/kg. xylazine 2mg/kg were done to evaluate effect of anesthesia in Siberian tiger White tiger and Bengal tiger. Mean induction time(MIT), mean arousal time-(MAT). mean walking time(MWT) and clinical sign were evaluated. The results were as follows. MIT were taken 16.1$\pm$3.5 minutes for Siberian tiger. 15.5$\pm$2.4 minutes for White tiger and 12.3$\pm$2.5 minutes for Bengal tiger. MAT were taken 44.2$\pm$9.5 minutes for Siberian tiger, 48.3$\pm$8.6 minutes for White tiger and 58.7$\pm$5.8 minutes for Bengal tiger. MWT were taken 110.6$\pm$11.6 minutes for Siberian tiger, 106.7$\pm$13.1 minutes for White tiger and 99.6$\pm$10.2 minutes for Bengal tiger. Nausea. vomiting. salivation. severe convulsion. sudden decreased respiration and dyspnea were observed in Siberian tiger during sedation and anesthesia. Also, nausea, vomiting, salivation and convulsion were observed in White tiger and Bengal tiger but the clinical signs were more mild than Siberian tiger. The Bengal tiger which used combined ketamine 5mg/kg , xylazine 1mg/kg were shown reduced induction time compare with combined administration ketamine 8mg/kg, xylazine 2mg/kg in Bengal tiger as 10.8$\pm$32 minutes for MIT. 32.3$\pm$4.3 minutes for MAT and 78.5$\pm$7.3 minutes for MWT Vomiting and convulsion were observed during induction time but there were no nausea and salivation. The present results suggested that preventive methods against severe convulsion and dyspnea should be required in Siberian tiger when combined anesthesia of ketamine 8mg/kg, xylazine 2mg/kg used. Combined anesthesia of ketamine 5mg/kg, xylazine 1mg/kg in Bengal tiger might be very effective for simple surgical procedure and diagnosis.
얼룩말에 있어서 Streptococcus equi에 의한 간농양 발생 1례
신남식,권수완,한덕환,Shin Nam-Sik,Kwon Soo-Wahn,Han Duk-Hwan 한국임상수의학회 1993 한국임상수의학회지 Vol.10 No.1
In this case, Grant's Zebra which had been bred and exhibited in Farmland Zoological Garden for 4 years, died after treated dystocia. Result in autopsy, she had large hepatic abscess, and blood chemistry were increased G07, GPT and total billirubin. The microbiological culture with the hepatic abscess idetified the Streptococcus equi. It is diagnosed of hepatic abscess which was caused by Streptococcus equi infection.
개의 치석제거를 위한 마취에 있어 Ketamine HCl/Propionyl promazine HCI과 Tiletamine HCl/Zolazepam HCl의 투여효과
신남식,최윤주,권수완,한덕환,박현종,권오경,Shin Nam-Sik,Choi Youn-Ju,Kwon Soo-Wahn,Han Duk-hwan,Park Hyun-Jong,Kweon Oh-Kyeong 한국임상수의학회 1993 한국임상수의학회지 Vol.10 No.2
To study effective dossage and administration route for scaling, ketamine HCl/propionyl promazine HCl(ketamine) combination and tiletamine HCl/zolazepam HCl(zoletil) were administered in one hundred six dogs. The dogs were toy poodle, Yorkshire Terrier, Pekingese and Chihuahua. Scaling and polishing time, possible treatment time after the first injection of anesthetics, the number of anethesia added, presence of tongue movement during anesthesia, the presence of swaying sign during recovery and respiration were evaluated. The possible treatment time after the first Injection of anesthetic in toy poodle were 26.3${\pm}$3.0 minutes with intravenous(IM) treatment of ketamine 10mg/kg, and 21.4${\pm}$6.6 minutes with intramuscula(IM) treatment of zoletil 8mg/kg, In Yorkshire Terrier were 19.51: 1.7 minutes with IV treatment of ketamine 10mg/kg. 19.0${\pm}$5.2 minutes IM and 20.8${\pm}$6.1 minutes with IM treatment of zoletil 5mg/kg,24.8${\pm}$3,5 minutes with IM treatment of zoletil 8mg/kg. In pekingese were 27.5${\pm}$2.1 minutes with IM treatment of ketamine 10mg/kg,28.0${\pm}$4.2 minutes with IM treatment of zoletil 8mg/kg. In Chihuahua were 19.5${\pm}$1.9 minutes with IV treatment of ketamine 7mg/kg, 17.5${\pm}$1.7 minutes with IM treatment of ketamine 10mg/kg and 20.3${\pm}$3.8 minutes with IM treatment of zoletil 5mg/kg, 21.2${\pm}$5.5 minutes with IM treatment of zoletil 8mg/kg. Swaying sign was observed in all group during recovery time, espically, in toy poodle and Yorkshire Terrier which administered zoletil 8mg/kg IM showed more severe swaying sign. The present results suggested that injection of zoletil 8mg/kg IM might be relatively effective for scaling in Chihuahua Within 20 minutes treatment for scaling in Yorkshire Terrier and Chihuahua, IM treatment of ketamine 7 to 10mg/kg is recommended.
자이언트 판다(Ailuropoda melanoleuca)에서 발생한 Yersiniosis 치료 1례
신남식,최윤주,권수완,한덕환,이기환,정희경,이창우,채찬희,김선중,권오경,이흥식,엽지용,Shin Nam-sik,Choi Yoon-ju,Kwon Soo-wahn,Han Duk-hwan,Lee Gi-hwan,Jeong Hee-kyoung,Lee Chang-woo,Chae Chan-hee,Kim Sun-joong,Kweon Oh-kyeong,Lee Heung-sh 한국임상수의학회 1995 한국임상수의학회지 Vol.12 No.1
Two giant pandas, which come from China have been roared in Yong-in Farmland zoo since 1994. One of them, which is female and 2 years old showed anorexia, mucous diarrhea and severe abdominal pain. It revealed neutrophilia and hypokalemia which suggested inflammation and loss of electrolytes by diarrhea. The mucous material contained intestinal mucoid epithelim which was infected Gram negative bacilli and infiltrated with neutrophils. The antibacterial therapy with nafcillin and ampicillin was not successful. Yersinia entrocolitica was implicated as a causative organism in the occurrence of bacterial enteritis. This organism had resistance to ampicillin, chlorampenicol, cefalothin, tetracycline, trimetoprim-sul-famethoxazole, erythromycin, gentamicin, kanamycin, carbanicillin and danofloxacin. It responded to the simultaneous administration of cefopherazone, flunixin-meglumine, physiological saline, Lactate Rainger's solution, sodium bicarbonate, KCL and vitamins and recovered after a period of 30days.
허권,배지선,최재훈,신남식,이기환,권수완,김대용,Hur, Kwon,Bae, Ji-Seon,Choi, Jae-Hoon,Shin, Nam-Sik,Lee, Ki-Whan,Kwon, Soo-Wahn,Kim, Dae-Yong 한국수의병리학회 1998 한국수의병리학회지 Vol.2 No.2
A total of 5 animals including 3 raccoons, 1 badger, and 1 fennec fox kept in outdoor exhibits at the Everland Zoological Gardens showed depression, anorexia, dyspnea, serous oculonasal discharge, diarrhea, and convulsions. All the affected animals died within 10 days after the onset of clinical signs. This outbreak lasted about 4 months. On necropsy, major gross lesions were confined to the lungs. Red to grey sublobular to lobular consolidations with various sized tan to reddish spots were observed in the lungs. Histopathologically, the pulmonary lesions were characterized by acute to subacute bronchointerstitial pneumonia with secondary bacterial or adenoviral infections. Intracytoplasmic eosinophilic inclusion bodies compatible with canine distemper virus (CDV) were found in the lung, urinary bladder, kidney, intrahepatic bile duct, stomach, small and large intestines. Multifocal areas of severe demyelination and accumulation of gitter cells or nonsuppurative inflammation were seen in the brains of 2 raccoons. CDV -specific antigens were demonstrated in the lung sections on immunofluorescent assay. The present report describes an outbreak of CDV infection in a zoo and indicates the range of susceptible zoo animal species.