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예비유아교사를 위한 구성주의적 접근 유아과학교육 수업 탐색
백은주(Eun Joo Baik),구정아(Jeong A Koo) 한국아동학회 2012 兒童學會誌 Vol.33 No.2
This study investigated the contents and methods of science education classes based on the largely constructivist approach of pre-service early childhood teachers, The subjects of this study consisted of 8 junior students from the Early Childhood department and for reference data, reflective journals, interviews, activity planning sheets, recordings of trial lessons, and lesson analysis were used. The results of this study were as follows. First, changes in key points and contents for children science education were found, and reflective journals, interviews, activity planning sheets, recording of trial lessons, and lesson analysis clearly supported these results. Second, the actual changes in the constructivist approach to children`s science education had a great impact upon the individual characters of the pre-service early childhood teachers. However, with the study period being limited to only one semester, it was found that the potential of this study to lead to any practical changes was simlilarly limited.
염산비퀴딜 캡슐 및 알리벤돌 정의 용출시험에 관한 연구
황정분(Joungboon Hwang),구은주(Eun Joo Koo),고서연(Seu Youn Go),조경철(Kyung Chul Cho),문현주(Hyun-Ju Moon),조수열(Soo Yeul Cho),강찬순(Chan Soon Kang),손여원(Yeo Won Shon),김영옥(Young Ok Kim),손경희(Kyung Hee Sohn),조대현(Dae Hyun 대한약학회 2010 약학회지 Vol.54 No.5
The dissolution test method and an analytical procedure by HPLC were developed and validated for viquidil hydrochloride capsules and alibendol tablets. These drugs were not yet characterized by the dissolution specifications in Korean Pharmaceutical Codex. So, with each reference and test drugs, we did the preliminary and standard experiments based on the Korean Pharmacopeia Guideline of dissolution testing for solid oral dosage forms. The dissolution test for viquidil hydrochloride capsules was carried out under sink conditions as follows: dissolution medium water, paddle rotation speed 50 rpm and vessel volume 900 ml. More than 90% of its label amount was released within 30 min in this method. Also the dissolution test for alibendol tablets was carried out under sink conditions as follows: dissolution medium water, paddle rotation speed 100 rpm and vessel volume 900 ml. More than 90% of its label amount was released within 45 min in this method. The dissolution samples were analyzed with a precise and accurate HPLC method. The developed dissolution test showed specificity, linearity, precision and accuracy within the acceptable range. The dissolution testing method described above was adequate for the purpose and may be proposed as a pharmacopeial standard to assess the performance of viquidil hydrochloride capsules and alibendol tablets.
Growth Inhibitors of Lettuce Seedlings from Curvibacter sp. GA75-1
Lam Hoang(황람),Gil-Jae Joo(주길재),Won-Chan Kim(김원찬),Eun-Ju Yang(양은주),Sang-In Kim(김상인),Sang-Man Lee(이상만),Jae-Ho Shin(신재호),In-Koo Rhee(이인구),Kyung-Sik Song(송경식) 한국원예학회 2009 원예과학기술지 Vol.27 No.2
식물생장억제제의 분리와 동정을 위하여 500여 종의 토양미생물로부터 상추 유묘에 대하여 강한 저해활성을 나타내는 미생물 균주 GA75-1을 선발하였다. 이 균주는 16S rRNA의 핵산염기서열 분석결과, Curvibacter sp.로 동정되었다. 이 균주의 배양 여액에 대하여 dichloromethane, ethyl acetate 및 butanol을 이용하여 순차적으로 분배한 다음, 강한 활성을 나타내는 butanol 가용성분획에 대하여 활성 지향형 분리를 통하여 화합물 1과 2의 두 가지 화합물을 분리하였다. 1과 2는 상추유묘의 뿌리 생장을 50㎎ L⁻¹에서 각각 56.8과 54.1% 저해하였으며, 줄기생장을 22.5 및 47.3% 저해하였다. 1과 2는 ¹H-NMR과 EI-MS 분석을 통하여 각각 uracil과 4-methoxybenzoic acid로 동정되었다. 1과 2는 50% 뿌리성장 저해농도 (IC₅₀) 값이 48.4와 49.1㎎ L⁻¹이었으며, 줄기에 대하여는 IC₅₀값이 각각 > 100.0와 51.3㎎ L⁻¹이었다. Uracil 유도체는 매우 잘 알려진 제초제 군에 속하나 uracil 자체에 대한 제초활성은 본 보고가 처음이며, 4-methoxybenzoic acid가 상추유묘에 대한 저해제로서 Curvibacter sp.에서 분리 보고된 것도 이번이 처음이다. 상기 화합물을 함유하는 Curvibacter sp. GA75-1은 식물의 도복 방지제, 또는 생물농약으로 이용될 수 있을 것으로 기대된다. The microbial strain GA75-1, which exhibited growth inhibitory activity on lettuce seedlings, was selected out of more than five hundred bacterial colonies by pot experiment for isolation and identification of plant growth retardants. The strain was identified as Curvibacter sp. by the nucleotide sequence of the 16S rRNA gene. The culture broth was consecutively partitioned with dichloromethane, ethyl acetate, and butanol. The bioassay-guided fractionation of butanol extract led to the isolation of compound 1 and 2 which inhibited 56.8 and 54.1% of lettuce root elongation and 22.5 and 47.3% of shoot growth at 50 ㎎ L⁻¹, respectively. From ¹H NMR and EI-MS spectra, 1 and 2 were identified as uracil and 4-methoxybenzoic acid, respectively. The concentrations of uracil and 4-methoxybenzoic acid required for 50% inhibition of root were 48.4 and 49.1 ㎎ L⁻¹ and of shoot were > 100.0 and 51.3 ㎎ L⁻¹, respectively. Uracil derivatives are one of very well-known herbicide groups; however, this is the first report on the herbicidal effect of uracil itself on lettuce. In addition, 4-methoxybenzoic acid is firstly isolated from the genus C. lanceolatus as an inhibitor of lettuce seedling growth. C. lanceolatus containing the above compounds is expected to be useful as the lodging-preventer and/or biotic herbicide.
성정애,남철현,김성우,김귀숙,구현진,유은주,Sung, Jung-Ae,Nam, Chul-Hyun,Kim, Soung-Woo,Kim, Gui-Suk,Koo, Hyun-Jin,Yoo, Eun-Joo 대한예방한의학회 2006 대한예방한의학회지 Vol.10 No.1
The purpose of this study was to determine factors influencing patient satisfaction with medical services in hospital, which is classified into environmental aspect, human services and procedural services. Based on the results of literature review, the study focused on effects of social-demographical factors on patient satisfaction. The environmental aspect of medical care services included medical equipment and facilities, hygiene, ventilation, heating and air-conditioning, waiting and resting space, ward space and parking facilities. Procedural service included registration process, bill payment, waiting time after registration, examination and prescription as well as appointment process. Human services consisted of physicians listening to stories of patients, examination duration, physicians' explanation and physicians' service. As for nurses, explanation about disease, examination procedure and results, kindness and nursing care were evaluated. Services provided by other staff members were also evaluated. Patient satisfaction, defined as individual attitude toward medical service as a whole, was measured using a questionnaire. A total of 700 in-or out-patients were surveyed in 6 hospitals with more than 300 beds in North Gyeongbuk Province. 1. The level of patient satisfaction varied with characteristics of patients. Male patients and those in their 30s had a low level of satisfaction. Dissatisfaction level was positively related to education level but negatively related to economic condition. 2. As for patient satisfaction with medical service providers and other employees in hospital, satisfaction level with physician's explanation about treatment was higher. But dissatisfaction levels with treatment duration and the lack of explanation about examination procedures were high, calling for improvement. Dissatisfaction level with nursing care was high, calling for training of nurses for better service. Given the low level of satisfaction with human services, hospital employees need to be trained to improve their service. 3. It Was found that administrative service was also a significant factor influencing patient satisfaction in addition to medical service. It is therefore important for hospitals to provide patients with prompt and convenient procedural service. 4. Environmental factors such as medical equipment and amenity facilities also affected patient satisfaction. Thus environmental condition, procedural service and human service are all important to improve medical service in hospital. In summary, procedural service was the most significant factor for patient satisfaction. The level of satisfaction in patients was also affected by human service and environmental condition. It is therefore necessary to take patient-oriented approach in providing medical service in an effort to improve patient satisfaction. The finding of a lower level of satisfaction with human service signifies the need for training of healthcare providers and other hospital employees for better services. The introduction of advanced management programs is also needed to improve procedures that patients go through in hospitals.