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증예(症例) : 장기간 Furosemide 사용후 발생한 신석회화증 1예
강경표 ( Kyung Pyo Kang ),이강휴 ( Kang Hyu Lee ),라방주 ( Bang Joo La ),문치영 ( Chi Young Moon ),고정곤 ( Jung Ghon Ko ),김원 ( Won Kim ),박성광 ( Sung Kwang Park ),강성귀 ( Sung Kyew Kang ) 전북대학교 의과학연구소 2001 全北醫大論文集 Vol.25 No.2
본 저지들은 성인에서 체중 조절을 목적으로 이뇨제를 장기간 오용하여 발생한 신석회화증을 경험하고 이에 대한 문헌고찰과 함께 보고하는 바이다. Nephrocalcinosis in the adult has many causes, some of which reflect serious renal disease. The major abnormal imaging pattern is the large, diffusely hyperechoic kidney with abnormal architecture. Its differential diagnosis includes hypercalcemia, hypercalciuria, hyperparathyroidism, sarcoidosis, uremia, increased Ca×P, metastatic calcification. The ultrasonic screening of the patients is essential in the evaluation. Other causes of the enlarged hyperechoic kidneys with abnormal architecture include chronic diuretics abuse, medullary sponge kidney and gouty nephropathy. Furosemide and acetazolamide are often used concurrently to control weight in young woman. We experience a case of nephrocalcinosis associated with chronic furosemide abuse. We report that long-term furosemide abuse can cause medullary nephrocalcinosis in adults.