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강탁림,Kang Tak-Lim 대한예방한의학회 1998 대한예방한의학회지 Vol.2 No.1
The antilipidperoxidative and hepatopreventive effects of Houttuynia cordata extract(HCE) were investigated at the level of liver homogenates and serum of SD rats intoxicated EtOH(3g/kg for 3days). We measured MDA(malondialdehyde) in the live. homogenate, AST(1-aspartate-2-oxoglutarate aminotransferase) and ALT( 1-alanine-2-oxoglutarate aminotransferse) in the serum. The analysis of the measurement indicated that HCE reduced MDA, ALT and AST significantly and their reduction was in relation to dose dependence. In rat liver homogenate intoxicated with EtOH, HCE treatment group inhibited lipidperoxidation by 50-75%. In rat serum intoxicated EtOH, HCE inhibited AST and ALT by 40-70%.
가미온담탕(加味溫膽湯)이 스트레스성 뇌신경전달물질(腦神經傳達物質) 변화(變化)에 미치는 영향(影響)
강탁림,Kang Tak-Lim 대한예방한의학회 2001 대한예방한의학회지 Vol.5 No.2
To elucidate the preventive effect of oriental medicine Gami-Ondamtang(GO) on stress, we investigated the physiological change of rats which were applied immobilization stress. For immobilization stress, rats were placed in restrainer for 12 hours a day for 3 days. During application of stress, body weight of rats was measured. After sacrifice, 8 organs were taken for measurement of organ weight. Brain was sectioned into 4 parts that are Frontal Cortex, Corpus Striatum, Hypothalamus and Hippocampus. Each part was homogenated and its catecholamine and serotonin contents were measured with HPLC. In our study, stress mainly induced increase of concentration of neurotransmitters in brain without other significant physical change of rats. GO inhibited stress induced changes of neurotransmitter content in brain.
고삼(苦蔘)(Sophorae Radix)의 생체 반응에 대한 연구(I)
강탁림,황귀서,KANG, TAK-LIM,HWANG, GWI-SEO Research Institute of Korean Medicine 1992 한의학연구소 논문집 Vol.1 No.1
청열조습(淸熱燥濕), 거풍살충(祛風殺蟲)의 효능이 있는 고삼(苦蔘)의 체내 면역활성에 미치는 영향에 대해 실험한 결과 아래와 같은 지견을 얻었다. ICR 생쥐에 고삼(苦蔘) 수침액을 투여한 결과 백혈구수 및 면역장기 변화는 없었다. in vitro실험에서 IgM PFCs에 유의성 있는 영향을 주지 못했고, BSA를 주사한 생쥐에서의 Arthus 반응에도 영향이 없었다. 그러나 지연형 과민반응을 억제하였으며, 비특이적 면역에 관여하는 macrophage의 탐식능을 약간 저하시켰다. 이상의 결과 고삼(苦蔘) 수침액(水浸液)은 세포성 면역을 억제하는 것으로 사료된다.
강탁림,Kang Tak-Lim 대한예방한의학회 1997 대한예방한의학회지 Vol.1 No.1
Despite of increasing market share, oriental hospitals are now facing profit deterioration. In order to contribute to both better policy making of the Government Md corporate planning in the part of the individual hospitals this study attempted to identify the oriental hospital's financial characteristics. financial performance data for 1995, published by the Korea Institute of Health Services Management, were analysed from the structural perspective of patient composition, capital and resources input, medical revenue and costs, and financial efficiency and profitability. Some financial characteristics were drawn based on the results of the analysis. The areas that require corrective action and future study were also suggested.
한방병원 입원한자의 진료과별 및 재원일별 평균진료비의 분포적 특성
강탁림,Kang Tak-Lim 대한예방한의학회 2000 대한예방한의학회지 Vol.4 No.1
This study was performed to find out characteristics of daily average medical charge of the inpatients of an oriental medical university hospital in TaeJeon. The sample of the study was 966 inpatients discharged from the 4 clinical departments of th hospital from January 1 to June 31, 1998. The major findings are as follows : 1. The average length of stay was 15.6 days in dept. of Internal Medicine, 16.9 in Acupuncture, 10.1 in Neuro-psychiatry and 24.3 in Physical therapy Daily average medical charge of the depart ments was 70,517 Won 62,011 Won, 82,750Won and 65,390 Won respectively. 2. The daily average medical charge of the departments was highest in the first day of admission. From the second day, it maintained a lower and relatively constant level, but showing slight fluctation in the latter halt of the hospital stay.
지유의 수치에 관한 연구 -볶은 지유로부터 불리된 토멘토솔린산-
강탁림(Tak Lim Kang),박만기(Man Ki Park) 대한약학회 1994 약학회지 Vol.38 No.6
Some traditional herbal drugs have been used after processing to modify its activities. For example, roasted "chiyu"(Sanguisorbae radix) has been used as antihemorrhagics while raw one used as anti-emetics. The composition of herbal drug is expected to be changed during this process. We tried to reveal the compositional difference between raw and roasted "chiyu", and isolated a compound which is not present in raw one but in processed one. The structure of the isolated compound was elucidated as tomentosolic acid. The content of tomentosolic acid in roasted "chiyu" was approximately 0.05%.
홍상진,강탁림,Hong Sang-Jin,Kang Tak-Lim 대한예방한의학회 2002 대한예방한의학회지 Vol.6 No.1
Health industry, a knowledge based high value-added industry, is being considered as a strategic area for the 21C and many advanced countries are making every endeavors for the promotion of health industry along with information technology, new materials, and mechatronics. Korean health industry, however, has been excluded from the governmental supports as well as bound by strict regulation so far, and there is a significant gap in technology compared with advanced countries. In 21C, technology is the main factor of national competitiveness and that is why the role of R&D institutes are so important in the high level of competition to cope with the technology protection policies of advanced countries. In this article, with Directory of Korean R&D Institutes published by Korea Industry Technology Association, I reviewed the trends of R&D institute of health industry. Main findings of the research can be summarized as follows. The portion of health industry R&D institute is 3.6% of total R&D institute but the amount of R&D investment is over than 5% This means health industry are knowledge based and R&D intensified industry, meanwhile the variations of same industry R&D institutes of health industry is huge in R&D investments and other activities. Regional distributions of health industry institutes show some kind of different patterns in each industry areas. Medical devices and Medical informatics's preference of metropolitan region are distinguished with other industry areas. Many of the institutes are located in same site of it's company rather than operating separate building for R&D specific uses. It is better for transforming ideas to products and close cooperation of research body with product lines, but it is a handicap for networking and communicating with other research institutions too. It takes 18.4yrs for bearing R&D institute on the average. For a long times 'copy products' or 'me too products' policies were easy way to maintain business entities. But recently, it is recognized that research activities are essential component of sustaining it's own business firms. This means technology itself is leading power of corporation itself in the high level of competition.