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슬개골에 발생한 연골모세포종의 동맥류성 골낭종화 - 증례 보고 -
홍준석,김성곤,박종웅,강창석,Hong, Joon-Seok,Kim, Sung-Kon,Park, Jong-Woong,Kang, Chang-Suk 대한근골격종양학회 1999 대한골관절종양학회지 Vol.5 No.4
저자들은 우측 슬개골의 동통을 주소로 내원한 50대의 여자환자에게서 병변에 대해 소파술 및 골 이식술을 시행한 결과 이차성 동맥류성 낭종화한 연골모세포종을 확인하여 문헌 고찰과 함께 보고하는 바이다. Chondroblastoma of the patella is a uncommon benign neoplasm in the middle aged person. Furthermore, a hemorrhagic cystic change associated with chondroblastoma is extremely rare. We experienced a case of chondroblastoma which underwent hemorrhgic cystic change. A fiftyyear-old female patient has suffered from right knee joint pain for 1 month before. Dominant gross feature was hemorrhagic cyst which was not involved into the joint space. Soft tissue was curetted and it was diagnosed to be chondroblastoma. The case was treated with curettage and bone graft.
갑상선의 원주세포형 유두상 암종의 세침흡인 세포학적 소견 - 1예 보고 -
정지한,강창석,심상인,김병기,이교영,Jung, Ji-Han,Kang, Chang-Suk,Shim, Sang-In,Kim, Byung-Kee,Lee, Kyo-Young 대한세포병리학회 1999 대한세포병리학회지 Vol.10 No.2
The columnar cell variant of papillary carcinoma is a rare tumor of the thyroid, associated with aggressive behavior, early metastasis, and a rapidly fatal course. We present the fine needle aspiration cytologic(FNAC) findings of columnar ceil variant of papillary carcinoma with cytohistologic correlation. In the smears, the tumor fragments showed mainly papillary pattern and a few scattered individual cells were present around the papillary fragments. The tumor cells were columnar or cuboidal and exhibited pseudostratification of the nuclei. The nuclei were oval to elongated with finely stippled chromatin and inconspicous nucleoli. Neither nuclear grooves nor intracytoplasmic inclusion was found. The FNAC diagnosis was consistent with papillary carcinoma. Total thyroidectomy was done and the histologic finding of the mass showed a predominantly papillary and focal solid proliferation of columar cells with marked nuclear pseudostratification. The unique histopathologic features and highly aggressive nature of columnar ceil variant of papillary carcinoma require that this variant should be differeniated from common papillary carcinoma of the thyroid.
난소에서 발생한 내배엽동 종양의 복수의 세포학적 소견 - 1례 보고 -
정은선,김영신,강창석,심상인,Jeong, Eun-Sun,Kim, Young-Shin,Kang, Chang-Suk,Shim, Sang-In 대한세포병리학회 1995 대한세포병리학회지 Vol.6 No.2
The cytologic findings of endodermal sinus tumor of the ovary are reported. The cytologic preperations were obtained from ascitic specimens. The findings on Papanicolaou-stained smears included a clean background and poorly preserved atypical cells loosely arranged in irregular or papillary groups. At high magnification, the cells had ill-defined and microvacuolated cytoplasms, with an increased nuclear-cytoplasmic ratio and prominent nucleoli. Hyaline globules characteristic of the alpha-fetoprotein (AFP)-synthesizing cells of endodermal sinus tumor were observed within the cells with periodic-acid-Schiff(PAS) stain. The presence of PAS-positive hyaline globules can be regarded, therefore, as a diagnostic clue to endodermal sinus tumor in an appropriate clinical setting and in the presence of AFP production. The cytologic findings in a cell block is important, in addition to smears, to obtain more diagnostic clues. A preliminary cytomorphologic diagnosis of this highly malignant tumor is valuable as a guide in planning further immunocytochemical and serologic studies.
다수의 다핵 거대세포를 동반한 갑상선 유두상 암종의 세침흡인 세포학적 소견
김경미,이교영,강창석,심상인,김선무,Kim, Kyung-Mi,Lee, Kyo-Young,Kang, Chang-Suk,Shim, Sang-In,Kim, Sun-Moo 대한세포병리학회 1993 대한세포병리학회지 Vol.4 No.1
An unusual case of papillary carcinoma of the thyroid revealing numerous multinucleated giant cells in the aspiration biopsy cytology is reported. Papillary carcinoma is the most common malignant neoplasm of the thyroid and is frequently diagnosed by aspiration biopsy cytology. Recently, we experienced a case of papillary carcinoma with many multinucleated giant cells in a 55-year-old woman. The cytologic features are described.
사기질모세포종의 세침흡인 세포학적 소견 - 1예 보고-
이희정,김병기,강창석,정은선,Lee, Hee-Jeong,Kim, Byung-Kee,Kang, Chang-Suk,Jung, Eun-Sun 대한세포병리학회 2002 대한세포병리학회지 Vol.13 No.2
Utilization of fine needle aspiration cytology (FNAC) in the diagnosis of odontogenic tumors seems to have little attention. Ameloblastoma is the most common epithelial odontogenic tumor. However, the cytologic findings of ameloblastoma are described recently. We report a case of ameloblastoma diagnosed by FNAC. The aspirated blood-tinged mucoid fluid from maxillary mass showed a few clusters of tumor cells with distinct two-cell population: basaloid cells with palisading arrangement and squamous cells with more abundant and eosinophilic cytoplasm. Nuclear atypism, pleomorphism or mitosis were absent. A few keratinized bodies in the tumor cell clusters and the third component, stellate cells were also characteristic.
자궁경부 투명세포 샘암종의 자궁경부질 세포학적 소견 - 1예 보고 -
맹이소,김경미,강창석,이안희,Maeng, Lee-So,Kim, Kyouug-Mee,Kang, Chang-Suk,Lee, An-Hi 대한세포병리학회 2004 대한세포병리학회지 Vol.15 No.2
Primary clear cell adenocarcinoma of uterine cervix is rare and cytomorphology in the vaginal smear have not been previously described in Korean literatures. The cytologic characteristics of clear cell adenocarcinoma of the uterine cervix include : malignant cells with abundant, finely vacuolated cytoplasm ; hobnail appearance, and distinctive basement membrane-like hyaline materials within cellular aggregates. A 36-year-old woman presented with vaginal bleeding. Cytologic examination of vaginal smear and histopathologic examination of a radical hysterectomy specimen allowed the diagnosis of hemorrhagic tumor in the uterine cervix as a clear cell adenocarcinoma. Cytologic findings were very characteristic. The tumor cells had abundant, pale, finely vacuolated cytoplasm with indistinct cytoplasmic membrane. The nuclei were round to oval with finely dispersed chromatin. Extracellular basement membrane-like hyaline substance, which stained a light green color in Papanicolaou's preparation, was frequently observed within the cancer cell clusters.
췌장의 점액 낭샘암종의 세침흡인 세포소견 -1예 보고-
이경지,이교영,강창석,심상인,이아원,Lee,, Kyung-Ji,Lee, Kyo-Young,Kang, Chang-Suk,Shim, Sang-In,Lee, Ah-Won 대한세포병리학회 2005 대한세포병리학회지 Vol.16 No.2
Mucious cystic neoplasm of pancreas is a cystic neoplasm composed of columnar, mucin-producing epithelium and is supported by ovarian-type stroma. The key to the cytologic evaluation of pancreatic cystic lesions is to recognize the cytologic components as being diagnostic of a mucin-producing cystic neoplasm, as all of these neoplasms need to be resected. We report the use of fine needle aspiration cytology in the diagnosis of an invasive mucinous cystic carcinoma confirmed by partial pancreatectomy. The cytologic specimen showed a abundant mucin background and sheets or papillae of neoplastic cells. There are mucin-containing columnar cells that show a variable degree of cytologic atypia.
맹이소,이안희,강창석,김경미,Maeng, Lee-So,Lee, An-Hi,Kang, Chang-Suk,Kim, Kyoung-Mee The Korean Society for Cytopathology 2004 대한세포병리학회지 Vol.15 No.1
Development of an invasive squamous cell carcinoma within a branchial cleft cyst (branchiogenic carcinoma) is very rare and this case is the first description of cytologic findings in Korea. A 62-year-old man presented with a 5-month history of an enlarged right neck mass. Fine needle aspiration cytology of the mass showed low cellularity and the background containing proteinaceous debris, inflammatory cells, and histiocytes suggested a cystic nature. Abundant lymphocytes, a few anucleated squames, and rare atypical squamous cells with pyknotic nuclei and abnormal keratinization were also noted. After excision of the mass, histologic findings were consistent with a branchiogenic carcinoma. We recommend to raise the possibility of carcinoma (primary or metastatic) when we observe a few dyskeratotic cells in a cystic mass within the neck area, especially in an old male.
연수경,지미경,강창석,김병기,김선무,심상인,Yeon, Su-Kyeong,Jee, Mi-Kyung,Kang, Chang-Suk,Kim, Byoung-Kee,Kim, Sun-Moo,Sim, Sang-In 대한세포병리학회 1993 대한세포병리학회지 Vol.4 No.2
A case of presacral chordoma in a 55-year-old male diagnosed by aspiration biopsy cytology Is reported. Cytologically, three cell types were recognized in a mucoid background. large, mononucleated or binucleated physaliphorous cells with vacuolated bubbly cytoplasm; small, uniform and rounded non-vacuolated cells; and cells with microvacuolated and plump cytoplasm. The diagnosis of chordoma was possible because typical radiological and cytomorphological features were supported by the results of special staining and immunohistochemical staining with the cell block specimen obtained from the fine needle aspiration.
비전형적인 세침흡인 세포학적 소견을 보인 후복막강 부신경절종 - 1례 보고 -
김진아,김영신,강창석,이안희,김병기,심상인,김선무,Kim, Jean-A,Kim, Young-Shin,Kang, Chang-Suk,Lee, An-Hi,Kim, Byung-Kee,Shim, Sang-In,Kim, Sun-Moo 대한세포병리학회 1994 대한세포병리학회지 Vol.5 No.1
A case of retroperitoneal paraganglioma is presented with fine needle aspiration cytologic features. A 57-year-old woman complained of abdominal discomfort and left flank pain for 2 years. The abdominal CT scan revealed an ovoid mass left to the abdominal aorta. Percutaneous fine needle aspiration was performed from the mass. The smear revealed cellular sheets or groups on hemorrhagic background. The tumor cells were ovoid, round to spindle shaped with mild to moderate cellular pleomorphism. The nuclei were round to ovoid and had evenly dispersed chromatin and small nucleoli. The cytoplasm was amphophilic, finely granular and poorly defined. Cells having large or spindle nuclei were quite frequently observed, however, mitosis was not present The cytologic findings suggested paraganglioma, but the frequent spindle cell pattern and the pleomorphism made it difficult to exclude other endocrine tumors and sarcomas. The clinical, histological and ultrastructural findings as well as cytologic findings contributed to confirmatory diagnosis.