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      • KCI우수등재

        지방정부 관료의 동기와 예산 극대화 행태

        강윤호(Yoon Ho Kang) 한국행정학회 1999 韓國行政學報 Vol.33 No.4

        Niskanen은 예산결정과정에서 관료들이 공리주의적 동기에 기초하여 행동한다고 본다. 그러나 그의 모형에 비판적인 연구들은 관료들의 행태는 공리주의적인 것뿐만 아니라 공무의 동기등 다양한 동지에 기초하며 이루어지며, 제도적 맥락의 차이에 따라 그들의 행태가 달라질 수 있다고 본다. 본 연구는 우리 나라 지방행정의 제도적 맥락이 지방정부 관료들의 인센티브·동기를 어떻게 구조화시키며, 지방정부 관료들이 예산결정과정에서 어떤 인센티브·동기에 기초하여 행동하는지를 살펴보고자 하였다. 분석결과 우리 나라 지방행정의 제도적 맥락하에서, 공리주의적 동기, 공무동기, 집단적 편익추구 동기 등 다양한 동기가 관료의 행태 배후에 존재하고 있음을 확인하였다. 그 중에서 공리주의적 동기와 공무동기가 지방정부 관료의 예산 극대화 행태에 영향을 미치고 있는 것으로 나타났는데, 공리주의적 동기의 영향이 더 큰 것으로 나타났다. 그리고 지방정부 관료들은 Niskanen이 주장한 것처럼 예산 극대화 추구자에 가까운 행태를 보이는 것으로 나타났다.

      • SCOPUSKCI등재
      • KCI등재후보

        기관지천식 환자에서 Disodium cromoglycate 치료효과의 예측인자

        강윤정(Yoon Jeong Kang),고형기(Hyoung Gee Koh),신종욱(Jong Wook Shin),임성룡(Seong Yong Lim),최재선(Jae Sun Choi),유지훈(Ji Hoon Yoo),김상훈(Sang Hoon Kim),박인원(In Won Park),최병휘(Byoung Whu Choi),허성호(Sung Ho Hue) 대한내과학회 1997 대한내과학회지 Vol.52 No.1

        N/A Objectives: Although DSCG protects against the stimuli of various bronchoconstictor, such as exercise, it is not effective to all patients. There seems to be no therapeutic predictor that determines effectiveness of DSCG on bronchial asthma. Although it is commonly assumed that children with predominantly allergic asthma have a better response to DSCG therapy than adult patient, this has not been convincingly demonstrated, and even adult with late onset nonallergic asthma may benefit. In this study, we evaluated the factors that potentially influenced the ability of DSCG to reduce bronchial hyperresponsibility. Methods: The treatment groups were sub-divide into effective group(n=14) and ineffective group(n=6) on the basis of significant improvement of followedup PC20 after long term therapy of DSCG. We compared clinical and laboratory data and pulmonary function test between two groups. Resutls: 1) Disease durtion and pre-treatment pulmonary function (FEV1% predicted, FVC% predicted value) may play a role in determining effectiveness of DSCG on bronchial asthma(p<0.05). 2) Allergic rhinitis history seems to have been associated with effectiveness of DSCG(p<0,05). But this findings was not clearly demonstrated the association of atopic status because skin test, eosinophil count, serum IgE level were not significant difference between two groups(p>0.05). Conclusion: These results show that DSCG is effective in adult chronic asthma and early administration of DSCG, good pulmonary function test and allergic rhinitis history may lead to more favorable outcome.

      • KCI등재

        당근의 알콜불용성 잔사와 셀룰로오스 분획의 p-Hydroxybenzoic Acid 추출에 미치는 시판 식물세포벽분해효소의 영향

        강윤한(Yoon-Han Kang) 한국식품영양과학회 2005 한국식품영양과학회지 Vol.34 No.10

        Driselase, Cellulase, Macerozyme R-200, Macerozyme R-10 및 Sumyzyme MC 등 5종의 시판 식물세포벽분해효소가 당근의 세포벽물질(CWM)로부터 제조한 알콜불용성 잔사(AIR)와 cellulose fraction의 p-hydroxybenzoic acid 추출에 미치는 영향을 조사하였다. 당근 AIR의 주된 페놀화합물은 p-hydroxybenzoic acid로 1,977 ㎍/g AIR였으며, vanillin, ferulic acid, p-hydroxybenzaldehyde가 각각 55.9, 13.6, 10.6 ㎍/g AIR인 것으로 나타났다. 효소에 함유되어 있는 ferulic acid의 함량은 Driselase, Cellulase, Macerozyme R-200, Macerozyme R-10, Sumyzyme MC에서 각각 2,319, 2,060, 391, 95.2, 34.1 ㎍/g인 것으로 나타났다. 이들 효소와 세포벽물질과의 반응을 조사한 결과, Driselase와 AIR의 반응 후 유리된 p-hydroxybenzoic acid의 함량은 56 ㎍/g AIR로 알칼리(4 M NaOH) 추출한 총량의 2.8%에 해당한다. 따라서 p-hydroxybenzoic acid는 AIR과 셀룰로오스 분획으로부터 이들 효소에 의해 분리되기 어려운 것으로 나타났다. Five different plant cell wall degrading enzymes were tested for their ability to release p-hydroxybenzoic acid from carrot alcohol insoluble residue (AIR) and cellulose fraction. Phenolics of AIR from cell wall materials (CWM) in carrot were found to consist primarily of p-hydroxybenzoic acid (1,977 ㎍/g AIR) with minor contribution from vanillin (55.9 ㎍/g AIR), ferulic acid (13.6 ㎍/g AIR) and p-hydroxybenzaldehyde (10.6 ㎍/g AIR). The contents of ferulic acid in Driselase, Cellulase, Macerozyme R-200, Macerozyme R-10 and Sumyzyme MC were 2,319, 2,060, 391, 95.2, 34.1 ㎍/g, respectively. Incubation of Driselase with AIR released only 2.8% of the total 4 M NaOH extractable p-hydroxybenzoic acid. These results indicate that commercial five plant cell wall degrading enzymes can not release p-hydroxybenzoic acid from carrot AIR and cellulose fraction.

      • KCI등재

        일반모와 미세모의 형태에 따른 인조치면세균막 제거 효과

        강윤미 ( Yoon Mi Kang ),이병진 ( Byoung Jin Lee ),김동기 ( Dong Kie Kim ) 대한예방치과·구강보건학회 2011 大韓口腔保健學會誌 Vol.35 No.3

        Objectives. Toothbrushing is the most fundamental self-help oral care, essential for the removal of dental plaque and food debris which can lead to caries or periodontal diseases. In order for patients to effectively select ideal toothbrush and maintain oral health, this study investigated the efficacy of different toothbrushes available on the market in the removal of dental plaque. Methods. A total of 156 pieces, from each of the three different types of standard manual toothbrushes and three slim-bristle type brushes for adults were randomly selected to be used as experiment units. The bristles of the different brushes were analyzed through a number of different processes. Data analysis was performed with Kruskal Wallis test and Man-Whitney`s U-test, Multiple linear regression at the significance level of alph=0.05. Results. The average surface area from which the artificial dental plaque was removed using the standard manual toothbrushes was 116.41 mm2 and using the slim bristle toothbrushes it was 121.82 mm2. The average buccal surface area from which the artificial dental plaque was removed using the standard manual toothbrushes was 86.93 mm2, and 88.11 mm2 using the slim bristle the slim bristle toothbrushes. The average dental sub-gingival area from which the artificial dental plaque was removed using the standard manual toothbrushes was 4.95 mm2 and 5.32 mm2 for the slim bristle toothbrushes. The average proximal surface area from which artificial dental plaque was removed using the standard manual toothbrushes was 24.79 mm2, and 28.38 mm2 for slim bristle ones. A statistically significant difference between the standard manual toothbrushes and the slim bristle was detected in the proximal surface (p<0.05). For the group consisting of the standard manual toothbrush, It was found that the smaller the difference in the length of implant brush, the greater the amount of plaque that was removed (p<0.05). Conclusions. According to the findings of the study, the factors influencing effective toothbrushing and brush designed indicate a need for further studies.

      • SCOPUSKCI등재

        솔잎추출물이 고지방식이를 급여한 흰쥐의 혈청과 간장 지질조성에 미치는 영향

        강윤한(Yoon-Han Kang),박용곤(Yong-Kon Park),하태열(Tae-Youl Ha),문광덕(Kwang-Deog Moon) 한국식품영양과학회 1996 한국식품영양과학회지 Vol.25 No.3

        솔잎추출물 급여가 고지방식이를 섭취한 흰쥐에서 혈청과 간장 지질조성에 미치는 영향을 검토하기 위하여 고지방식이와 함께 용매 대비 솔잎 건조분말을 3, 6% 함유하도록 물과 70% 아세톤으로 추출하여 얻은 열수추출물과 70% 아세톤추출물을 급여하여 대조군(Control) 이외에 3% 열수추출물 급여군(WE-3), 6% 열수추출물 급여군(WE-6), 3% 아세톤추출물 급여군(AE-3), 6% 아세톤추출물 급여군(AE-6)으로 4주간 사육한 후 혈청과 간장중 지질성분을 측정하였다. 체중 증가량에 있어서 WE-6군이 통계적으로 유의하게 낮았으며 다른군들 사이에는 유의차가 없었다. 식이와 솔잎추출물 섭취량에 있어서는 각군에 따른 유의차는 없는 것으로 나타났다. 혈청 중 triglyceride 함량은 대조군에 비해 실험군 모두 다소 낮은 함량을 나타내었고, 총 콜레스테롤의 함량에 있어서도 대조군에 비해 WE-3군은 다소 낮은 것으로 나타났다. HDL-콜레스테롤 함량은 WE-3군이 대조군에 비해 유의적으로 높게 나타났으며, 인지질은 WE-3군이 AE-6군과 유의적 차가 있었다. β-Lipoprotein의 함량은 WE-6군을 제외한 전 실험군에서 대조군 보다 낮은 경향이었다. 동맥경화지수는 WE-3군에서는 현저하게 낮은 값을 나타내었다. 간장 중 총 지질 함량은 WE-3에서는 대조군에 비하여 유의하게 낮았으나 AE-6군은 유의적으로 높았다. 간장 중성지방 및 총 콜레스테롤 함량은 솔잎추출물 급여군 모두가 대조군에 비해 유의적으로 낮게 나타났다. 이상의 결과는 식이와 추출물 섭취량에는 유의적인 차이가 없어 영향을 미치지 않은 것으로 나타났으나 솔잎추출물 급여군 중 WE-3군에서는 혈청 지질 함량 및 동맥경화지수를 감소시켰고 HDL-콜레스테롤을 증가시킴으로써 고지혈증 개선효과가 있고, 간장에서의 중성지방과 총 콜레스테롤 등 지질농도의 상승 억제효과가 있음을 시사해주고 있다. The effects of pine needle extracts on serum and liver lipid contents were evaluated in rats. Thirty male Sprague-Dawley rats weighing 329±4 were divided into five groups and fed high fat diets for four weeks. Each group was administered with following pine needle extract : control, water ; WE-3, hot water extract(3% PN) ; WE-6, hot water extract(6% PN) ; AE-3, acetone extract(3% PN) ; AE-6, acetone extract(6% PN). Weight gains were significantly lower in WE-6 group than other groups. But there was no significant difference among other three groups. Intakes of diet and water containing the extract and the weights of liver, kidney, heart and spleen were not significantly different among the groups. The contents of serum and liver triglyceride in the WE-3 group were lower than those of control group. The contents of HDL-cholesterol in serum of the WE-3 group was significantly higher than other groups. The value of risk factor index(RFI) was determined to be low especially in case of WE-3 group. Due to pine needle extract administration, concentration of liver total lipid in WE-3 group was significantly lower than that of the control group. These results suggest that the WE-3 may reduce elevated levels of serum and liver lipid contents in rat fed high fat diet.

      • KCI등재

        Pepsin에 의한 Zein 가수분해물의 항균활성

        강윤정(Yoon-Jung Kang),이상덕(Sang-Duk Yi),이규희(Gyu-Hee Lee),오만진(Man-Jin Oh) 한국식품영양과학회 2006 한국식품영양과학회지 Vol.35 No.2

        효소에 의한 옥수수 단백가수분해물의 천연항균제로서의 이용가능성을 조사하기 위하여 zein 단백질에 단백 가수분해 효소를 작용시켜 얻어진 가수분해물의 항균활성을 측정하고 membrane filter로 한외 여과하여 항균활성이 가장 높은 분획을 HPLC로 분취한 후 항균활성을 측정하고 MIC, 각종 세균에 대한 생육저해농도를 측정하여 다음과 같은 결과를 얻었다. Zein 단백질에 6종의 단백분해효소를 작용시켜 제조한 가수분해물 중 pepsin으로 작용시킨 것이 항균활성이 가장 높았다. Membrane filter에 의하여 여과한 가수분해물의 항균활성은 M.W. 10,000~30,000에서 가장 높았으며 121℃에서 10분간 처리하여도 항균활성에 변화가 없는 열안정성이 매우 높았고 MIC는 2.5 ㎎/mL이었다. HPLC로 분리한 항균성 peptide의 N-말단 아미노산 조성은 leucine, glutamic acid, proline, phenylalanine, aspartic acid, argenine 순이었다. 분자량 10,000~30,000의 가수분해 동결 건조물을 3 ㎎/mL 농도로 nutrient broth 배지에 첨가하고 37℃에서 배양하였을 때 크게 생육이 저해되었다. A study was carried out to produce antimicrobial peptides from zein treated with proteases of six kinds. Among the proteases of six kinds, zein hydrolysate treated with pepsin showed the highest antimicrobial activity. The zein hydrolysate with pepsin was fractionated with membrane filter (30,000 10,000 and 3,000 molecular weight cut-off) and antimicrobial activity was measured for each fractions. Antimicrobial activity appeared greatly in the fraction below 3,000 (molecular weight cut-off). The fraction was re-fractionated by HPLC and substances of two peaks collected as a sample to measure antimicrobial activity. All of both peaks showed the antimicrobial activity but 1st peak exhibited a consistently higher antimicrobial activity than 2nd peak. Minimum inhibitory concentrations (MIC) were between 2.5 and 3.0 ㎎/mL. The peptide was heat-stable since antimicrobial activity was maintained after treated with heat for 20 min at 121℃. N-terminal amino acid sequence of peptide fractionated by HPLC was leucine, glutamic acid, proline, phenylalanine, aspartic acid and argenine. These results indicated that peptide isolated from zein hydrosate with pepsin can use as a natural preservative ingredient in food industry.

      • KCI등재

        남녀 대학생의 성지식, 성태도 및 생식건강증진행위에 관한 연구

        강윤선 ( Kang Yoon-seon ),황혜남 ( Hwang Hyenam ) 경희대학교 동서간호학연구소 2017 동서간호학연구지 Vol.23 No.1

        Purpose: Due to today`s sexual openness, college students may be exposed to frequent sexual relations, which can affect their adulthood reproductive health, pregnancy, and delivery. The purposes of this study were to explore the degrees of sexual knowledge, sexual attitudes, and reproductive health promoting behaviors in male and female college students and to identify their gender differences. Methods: A descriptive comparative design was used. A total of 181 college students(92 male and 89 female) were recruited. Data were collected between March 17 and April 8, 2016 using a convenience sample in a university located in Y city. Results: For male students, there was no correlation between two variables. For female students, reproductive health promoting behaviors had a significant relationship with sexual attitudes. Conclusion: These findings provide essential information that health care providers can use to increase their awareness of the importance of gender specific treatments when caring individuals.

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