자하거약침의 월경통에 대한 치료효과

강위창,조정효,이연월,손창규,조종관,유화승,Kang, Wee-Chang,Cho, Jung-Hyo,Lee, Yeon-Weol,Son, Chang-Gue,Cho, Chong-Kwan,Yoo, Hwa-Seung 대한약침학회 2005 Journal of pharmacopuncture Vol.8 No.1

Purpose : The purpose of this study was to identify the effects of Hominis Placenta Herbal Acupuncture(HPA) combined with Acupuncture compared with Acupuncture therapy. Methods : Data was collected from October 1st 2004 to February 28th 2005. A total of 8 women participated in this study. Of all subjects, 4 and 4 subjects were assigned to the experimental and the control group respectively. Subjects were treated three times a week. We used Visual Analogue Scale(VAS) for evaluating the effects of HPA. Results : There showed statistically boardline significance between the experimental group and control group(p=0.057). Conclusion : The results showed HPA has significant effects on menstrual cramps.

만성 긴장성 두통 환자와 정상 대조군의 압력통각 역치 변화에 대한 비교연구

김민정,강위창,홍권의,Kim, Min-Jung,Kang, Wee-Chang,Hong, Kwon-Eui 대한약침학회 2009 Journal of pharmacopuncture Vol.12 No.2

Although Chronic tension-type headache(CTTH) is one of the most common symptom in primary headache, there is no definite mechanisms. But muscular factors and psychological factors is supposed to be related with CTTH according to many other studies and pressure pain threshold(PPT) is used to measure muscular factors. Methods 1. We performed this study with 63 patients fulfilling the International Headache Societ criteria for chronic tension-type headache and 20 healthy control group and measured the PPT of temporal muscle and trapezius muscle. 2. We investigated the correlation between clinical characteristic and PPT. 3. Each of the CTTH groups and Control group is divided to four group again - HNP, Spondylosis, Sprain, Normal according to Cervical spine X-ray. Results 1. The PPT of temporal muscle and trapezius muscle in the CTTH is significantly lower than that of Control. 2. In CTTH group, the PPT has significant positive relation with duration of headache and continued time of headache. And the PPT has significant inverse relation with Frequency of headache and Level of headache. 3. In CTTH group, spondylosis group has the highest PPT and normal group is second. And there are significant difference between spondylosis group and the others. Conclusion : We found that PPT is strongly significant to measure muscular factor in CTTH.

치매 한의 평가도구 개발을 위한 기초 연구

류창희 ( Chang Hee Ryu ),정인철 ( In Chul Jung ),조성훈 ( Seung Hun Cho ),황의완 ( Wei Wan Hwang ),강위창 ( Wee Chang Kang ),이상룡 ( Sang Ryong Lee ) 대한한방신경정신과학회 2010 동의신경정신과학회지 Vol.21 No.4

Objectives: This study was performed to develop a standard instrument of oriental medical evaluation for dementia. Methods: The advisor committee on this study was organized by 17 neuropsychiatry professors of oriental medical colleges. The items and structure of the instrument were based on review of published literature. We took consultation twice from the advisor committee and we also took additional advices by e-mail. Results: We discriminated between bian-zheng and su-zheng from the answers of the advisor committee. We got the mean weight of each symptom and sign from the answers of the advisor committee. We got the final weight from the combination of the ratio of bian-zheng to the number of all answers of the advisor committee and mean weight. Conclusions: The instrument of oriental medical evaluation for dementia was developed through experts` discussion. If the validity and reliability of this instrument is confirmed through additional clinical trial, the instrument of oriental medical evaluation for dementia is expected to be applied to the subsequent research.

무응답이 있는 설문조사연구의 접근법 : 한국노인약물역학코호트 자료의 평가

백지은,강위창,이영조,박병주,Baek, Ji-Eun,Kang, Wee-Chang,Lee, Young-Jo,Park, Byung-Joo 대한예방의학회 2002 예방의학회지 Vol.35 No.2

Objectives : A common problem with analyzing survey data involves incomplete data with either a nonresponse or missing data. The mail questionnaire survey conducted for collecting lifestyle variables on the members of the Korean Elderly Phamacoepidemiologic Cohort(KEPEC) in 1996 contains some nonresponse or missing data. The proper statistical method was applied to evaluate the missing pattern of a specific KEPEC data, which had no missing data in the independent variable and missing data in the response variable, BMI. Methods : The number of study subjects was 8,689 elderly people. Initially, the BMI and significant variables that influenced the BMI were categorized. After fitting the log-linear model, the probabilities of the people on each category were estimated. The EM algorithm was implemented using a log-linear model to determine the missing mechanism causing the nonresponse. Results : Age, smoking status, and a preference of spicy hot food were chosen as variables that influenced the BMI. As a result of fitting the nonignorable and ignorable nonresponse log-linear model considering these variables, the difference in the deviance in these two models was 0.0034(df=1). Conclusion : There is a lot of risk if an inference regarding the variables and large samples is made without considering the pattern of missing data. On the basis of these results, the missing data occurring in the BMI is the ignorable nonresponse. Therefore, when analyzing the BMI in KEPEC data, the inference can be made about the data without considering the missing data.

화병의 불안 증상에 대한 시호가용골모려탕의 효능 임상연구 중간보고

최우창 ( Woo Chang Choi ),박대명 ( Dae Myung Park ),이상룡 ( Sang Ryong Lee ),강위창 ( Wee Chang Kang ),정인철 ( In Chul Jung ) 대한한방신경정신과학회 2012 동의신경정신과학회지 Vol.23 No.4

경계정충 변증도구 신뢰도 평가 및 개선방안 연구

최우창 ( Woo Chang Choi ),이헌수 ( Hun Soo Lee ),서복남 ( Bok Nam Seo ),강위창 ( Wee Chang Kang ),정인철 ( In Chul Jung ) 대한한방신경정신과학회 2014 동의신경정신과학회지 Vol.25 No.4

Objectives: The purpose of this study is to examine the test-retest reliability and to suggest methods to enhance reliability. Methods: Participants consisted of 145 patients with generalized anxiety disorder who were diagnosed by the Structured Clinical Interview for DSM-￥³ Axis ￥° Disorders. Participants were tested twice within one week. Results: The test-retest reliability of the Instrument of Pattern Identification for Jing Ji and Zheng Chong was examined in 145 patients and it was calculated as 0.3919. Internal Reliability of each part was calculated as 0.320~0.502. Reliability and concordance rate of symptoms are presented in the table. Frequency of symptoms and correlation between weight and frequency are also presented in the table. Conclusions: Based on these results, we have modified the Instrument of Pattern Identification for Jing Ji and Zheng Chong.

만성적 소음노출이 혈압에 미치는 영향에 대한 코호트연구

차태준,김장락,강위창,양승림,이충렬,유철인,이지호,Cha, Tae-Joon,Kim, Jang-Rak,Kang, Wee-Chang,Yaang, Seung-Rim,Lee, Choong-Ryeol,Yoo, Cheol-In,Lee, Ji-Ho 대한예방의학회 2002 예방의학회지 Vol.35 No.3

장기간의 소음노출에 의한 혈압상승 또는 고혈압의 발생에 대해서는 많은 연구에도 불구하고 결과가 다양하고 논란이 많은 실정이다. 이에 연구자는 혈압에 대한 소음의 영향을 보다 정확히 평가하기 위해서 일개 사업장을 대상으로 유사 노출군의 코호트를 구성하고 9년간의 추적조사를 실시하였다. 여기서 얻은 자료를 이용하여 소음노출수준별로 혈압의 연도별 변화경향을 파악하고, 혼란변수를 통제한 상태에서도 혈압의 변화에 대해 소음노출이 영향을 미치는가를 파악하고자 하였다. 부산지역의 일개 금속제품 제조업에서 근무하고 있는 530명의 남자 근로자를 1991년부터 1999년까지 혈압을 9년간 매년 계속 추적조사 하였으며, 조사 대상자들을 근무여건과 노출되는 소음수준(noise level category, 이하 NLC로 약함)에 따라 NLC-I (사무실 근로자, 60dB(A) 미만으로 노출, 155명), NLC-II(현장 기술지원자 및 검사원, 소음에 비정기적으로 노출, 75명), NLC-III (현장근로자, 85 dB(A)이하로 노출, 귀마개 또는 귀덮개를 착용, 167명), NLC-IV (현장근로자, 85 dB(A) 초과 노출, 귀마개와 귀덮개를 동시에 착용, 133명) 의 4군으로 구분하였다. 추적기간동안 소음수준별 혈압은 분산 분석을 이용하여 비교하였고, 혼합선형모형을 이용하여 추적기간동안(1992-1999년)의 보정된 통합평균혈압을 구하고 소음노출수준별로 비교하였다. 고려된 혼란변수는 기준연도(1991년)의 연령, 흡연여부, 음주량, 운동, 고혈압 가족력, 수축기 및 확장기 혈압과 체질량지수의 변화였다. 기준연도의 혈압과 혼란변수를 보정한 상태에서 각 연도별 혈압을 비교한 결과 수축기혈압은 9년째에서, 확장기 혈압은 2년째에서 대조군과 통계적으로 유의한 차이가 있었으며, 대조군의 평균 혈압이 전반적으로 증가되었다. 추적기간동안 혼란변수를 보정한 통합수축기 혈압은 대조군인 NLC-I과의 차이가 NLC-II는 1.7 mmHg, NLC-III는 2.0 mmHg, NLC-IV는 3.8 mmHg이었고, NLC-IV의 경우 그 차이가 통계학적으로 유의하였다. 확장기혈압의 경우에는 소음노출수준별로 유의한 차이가 없었다. 본 연구는 남성근로자에서 장기간의 소음노출은 혈압의 상승에 독립적인 영향이 있음을 시사하였다. Objective : Whether exposure to chronic noise induces an increase in blood pressure, or the development of hypertension, has not been established. A cohort study was performed to identify the effects of chronic noise exposure on blood pressure. Methods : 530 males working at a metal manufacturing factory in Busan, Korea were enrolled for the study. They were monitored for 9 consecutive years, from 1991 to 1999, with an annual health check-up. The subjects were divided into 4 groups, which were determines by noise level categories(NLC) according to noise intensity ; NLC-I: office workers, exposed to noise a level below 60dB(A) ; NLC-II: field technical supporters or supervisors, frequently exposed to workplace noise, wearing no hearing protection device; NLC-III: workers, exposed to workplace noise below 85dB(A), wearing ear plugs or muffs; NLC-IV: workers, exposed to workplace noise over 85 dB(A), wearing both ear plugs and muffs. Results : After controlling possible confoundens, such as baseline age, smoking, alcohol intake, exercise, family history of hypertension, systolic(SBP) of diastolic blood pressure(DBP) and changes in BMI (body mass index), the pooled mean for the systolic blood pressures, over the duration of the study period, were 3.8mmHg, 2.0mmHg and 1.7mmHg higher in NLC-IV, NLC-III NLC-II groups, respectively, than in the NLC-I group. There were no significant differences in the diastolic blood pressures between the groups. Conclusion : This study suggests that chronic noise exposure increases systolic blood pressure independently, among male workers.

감기에 대한 연교패독산의 유효성 평가를 위한 community-based 이중맹검 위약 대조군 연구

배한호(Han Ho Bae),강위창(Wee Chang Kang),박양춘(Yang Chun Park) 한의병리학회 2008 동의생리병리학회지 Vol.22 No.1

우리 나라 국민의 보완요법 이용률, 이용양상과 비용지출

강영호,이무송,구희조,강위창,홍창기,이상일,Khang, Young-Ho,Lee, Moo-Song,Koo, Hee-Jo,Kang, Wee-Chang,Hong, Chang-Gi,Lee, Sang-Il 대한예방의학회 1999 예방의학회지 Vol.32 No.4

Objectives : To determine the prevalence, pattern. and out-of-pocket expenditure of complementary and alternative medicine (CAM) utilization in Korean adult population. Methods : We conducted a representative telephone survey of 2,042 persons aged 18 or older. Data about any health problem, details of their use of medical doctors(MDs) offices/hospitals/pharmacies services and CAM during the preceding 12 months were collected with structured questionnaire. Results : The utilization rate of CAM among Korean adults was 29% in one year. A total of 231 kinds of CAM was identified from this survey. Annual out-of-pocket expenditure associated with CAM use in 1998 amounted to ${\xi}{\S}1.88$ billion and was comparable to 40.8% of out-of-pocket expenditure paid for MDs offices/hospitals/pharmacies services. Among those(N=424) who paid for both MDs offices/hospitals/pharmacies services an d CAM, 35.8% paid more for CAM. CAM gave more satisfaction than western medicine to those who had experience of both types of therapy. About half of CAM users were willing to recommend CAM to others. Disclosure rate to physician among CAM users was not high(40.6%). Conclusion : CAM became a popular source of health care in Korea, Korean spent a substantial amount of out-of-pocket money on CAM without any public control. Because CAM use is likely to be increased rapidly through lay referral system, health policy makers and health professionals should pay more attention to CAM for making appropriate utilization of CAM.

위험도 보정을 통한 병원간 제왕절개 분만율의 비교

이상일,하범만,이무송,강위창,구희조,김창엽,강영호,Lee, Sang-Il,Ha, Beom-Man,Lee, Moo-Song,Kang, Wee-Chang,Koo, Hee-Jo,Kim, Chang-Yup,Khang, Young-Ho 대한예방의학회 2001 Journal of Preventive Medicine and Public Health Vol.34 No.4

Objective : To determine the clinical risk factors associated with the mode of delivery decision and to compare cesarean section rates after adjusting for risk factors identified among Korean hospitals. Methods Data were collected from 9 general hospitals in two provincial regions by medical record abstraction during February 2000. A total of 3,467 cases were enrolled and analyzed by stepwise logistic regression. Performance of the risk-adjustment model (discrimination and calibration) was evaluated by the C statistic and the Hosmer-Lemeshow test. Crude rates, predicted rates with 95% confidence intervals, and adjusted rates of cesarean section were calculated and compared among the hospitals. Results : The average crude cesarean section rate was 53.2%, ranging from 39.4% to 65.7%. Several risk factors such as maternal age, previous history of cesarean section, placenta previa, placental abruption, malpresentation, amniotic fluid abnormality, gestational anemia, infant body weight, pregnancy-induced hypertension, and chorioamnionitis were found to have statistically significant effects on the mode of delivery. It was confirmed that information about most of these risk factors was able to be collected through the national health insurance claims database in Korea. Performance of the risk-adjustment model was good (c statistic=0.815, Hosmer-Lemeshow test=0.0621). Risk factor adjustment did lead to some change in the rank of hospital cesarean section rates. The crude rates of three hospitals were beyond 95% confidence intervals of the predicted rates. Conclusions : Considering that cesarean section rates in Korean hospitals are too high, it is apparent that some policy interventions need to be introduced. The concept and methodology of risk adjustment should be used in the process of health policy development to lower the cesarean section rate in Korea.