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인천지역 초중고등학교의 건축조건과 실내공기질과의 상관성 분석
강승아(Seung-A Kang),최상준(Sang-Jun Choi),김용식(Yong-Shik Kim) 한국생활환경학회 2008 한국생활환경학회지 Vol.15 No.2
Students spend an average of 4 to 14 hours a day in classrooms. Therefore, their health is greatly affected by the air quality of classrooms. The quality of air in classrooms has been deteriorated in recent years due to diversification of construction materials, increased application of chemical substances, and the lack of ventilation systems incorporated in classrooms. As a result, students who spend great deal of their time in newly constructed classrooms suffer from "Sick School Syndrome", a phenomenon similar to the "Sick House Syndrome". This has a potential of becoming a serious health concern, especially among young students who have not fully developed strong immune systems. On top of this, there are only few studies conducted on the air quality of classrooms, not to mention the complete absence of study done on the correlations between the classroom air quality and the building construction conditions. Based on the aforementioned background, this study presents some primary data based on the survey of classroom construction conditions and the measurements taken on the air quality of classrooms. Relationships between the classroom designs, and the density of pollutants are also analyzed and are included in this study. To summarize, there is a direct correlation between architectural materials and the density of harmful chemicals present in classrooms.
강승이(Seung Yi Kang),오수아(Soo A Oh),이학성(Hak Sung Lee),한성태(Sung Tai Han),신차균(Cha-Gyun Shin) 대한약학회 2005 약학회지 Vol.49 No.3
Human foamy virus (HFV) integrase mediates integration of viral c-DNA into cellular DNA. In this process, HFV integrase recognizes its own viral DNA specifically and catalyzes insertion of viral c-DNA. In order to study catalytic domains and residues, three deletion mutants and two point mutants of HFV integrase were constructed and analyzed with respect to enzymatic activities. The C-terminal deletion mutant showed decreased enzymatic activities while the N-terminal deletion mutant lost the activities completely, indicating that the N-terminal domain is more important than the C-terminal domain enzymatic reaction. The point mutants, in which an aspartic acid at the 164th position or a glutamic acid at the 200th position of The HFV integrase protein was changed to alanine, lost the enzymatic activities completely. However, they results suggest that the aspartic acid and glutamic acid at the respective 164th and 200th positions are catalytic residues for enzymatic reaction.
오수아(Soo A Oh),강승이(Seung Yi Kang),한성태(Sung Tae Han),안덕근(Dog Gn An),신차균(Cha-Gyun Shin) 대한약학회 2006 약학회지 Vol.50 No.2
Human foamy virus (HFV) integrase mediates integration of viral c-DNA into cellular DNA. In this process, HFV preintegration complex (PIC) in which integrase is a key component moves to nuclei of the infected cells and leads to integration of viral DNA to the cellular genome, which is essential in viral life cycle. In general nuclear localization signals (NLS) have been suggested to be involved in localizing retroviral PIC to muclei, but the mechanisms for nuclear localization of the HFV PIC remains unclear. To functionally identufy the NLS of HFV integrase, various subdomains of the protein were expressed as GFP fusions and fusions and their subcellular locations were analyzed with comfocal laser scanning microscopy. Wild type HFV integrase was karyophilic by targeting the fusion protein to nuclei of the COS-1 and 294T cells. Our results showed that strong NLS of HFV integrase was mapped to the C-terminal regions. In addition the karyophimic properties of N-ter- minal and central regions are not individually strong enough to direct localization of the fusion proteins to nuclei, but their cooperative activity for nuclear inport was comfirmed.
도시 신재생에너지 이용시스템 개발을 위한 사례조사 연구
고명진(Go Myeong-Jin),강승아(Kang Seung-A),고유미(Go Yu-Mi),왕문희(Wang Moon-Hee),최미영(Choi Mi-yuong),김용식(Kim Yong-Shik) 한국태양에너지학회 2008 한국태양에너지학회 학술대회논문집 Vol.- No.-
As the instability of international societies on the energy resources has increasingly been deepened due to excessive use of fossil fuels, the importance of energy saving and global environment protection has highlighted, So the interests in environment-friendly and stable new & renewable energy have been dramatically increased. The studies on reconstructing tile old-fashioned towns economically, socially and physically have been also significantly increased. In this urban regeneration, renewable-energy using systems were aggressively applied to overcome the energy and environmental problems of the existing towns. There have been many of studies on the compound applications of the renewable-energy using systems in the advanced countries while they are insufficient in Korea. As a preliminary study of urban renewable-energy using system development, this paper surveyed the foreign cases applied to key technologies such as geothermal energy, hydrogen fuel cell and bioenergy among the renewable-energies in urban built environment.