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베체트병과 동반된 Immunoglobulin A 신증에서 발생한 흉선암 1예
박세희 ( Se Hee Park ),김정호 ( Jung Ho Kim ),이정연 ( Jung Yoen Lee ),신석균 ( Sug Kyun Shin ),홍용국 ( Yong Kook Hong ),기정혜 ( Jeong Hae Kie ),강두영 ( Du Yong Kang ),이찬희 ( Chan Hee Lee ) 대한류마티스학회 2015 대한류마티스학회지 Vol.22 No.2
Behcet`s disease is a systemic inflammatory disorder of unknown etiology, characterized by recurrent oral aphthous ulcers, genital ulcers, uveitis, and skin lesions. Renal involvement is rare in patients with Behcet`s disease particularly immunoglobulin A (IgA) nephropathy. Other autoimmune diseases have been associated with increased risk of malignancy, but not Behcet`s disease. Some cases of Behcet`s disease accompanied by bladder cancer, thyroid cancer, stomach cancer, or hematologic malignancies have been reported. However, to the best of our knowledge, co-occurrence of Behcet`s diseases with thymic carcinoma has not yet been reported. We experienced a 49-year-old male patient who had been treated for Behcet disease and IgA nephropathy, who presented with a large mediastinal mass on chest x-ray. After thymectomy, he was diagnosed with thymic carcinoma with complete resection. (J Rheum Dis 2015;22:118-122)