제주도 시흥리 연안에 분포하는 바지락, Ruditapes philippinarum의 계절에 따른 생식소발달

강도형(Do-Hyung Kang),고티투타오(Thao T. T. Ngo),고광종(Kwang-Jong Koh),최광식(Kwang-Sik Choi) 한국수산과학회 양식분과 2004 韓國養殖學會誌 Vol.17 No.1

제주도 함덕 연안에 서식하는 구멍연잎성게 , Astriclypeus manni ( Verril 1867 ) 의 생태학적 특성에 관한 연구

강도형(Do Hyung Kang),최광식(Kwang Sik Choi),정상철(Sang Chul Chung) 한국수산과학회 1999 한국수산과학회지 Vol.32 No.3

The sand dollar, Astriclypeus manni is commonly encountered on a subtidal sand bottom along the coast of Cheju Island. Limited information has been reported on their biology despite their natural abundance. This study reports ecology and an annual reproductive cycle of the sand dollars present at Hamdoek, northern coast of Cheju Island. A. manni collected from Hamdock revealed that they are 80 to 200 ㎜ in test diameter. Sediment grain size analysis indicated that A. manni mostly occurs on medium (particle diameter of 500㎛) to very find sand (particle diameter of 125 ㎛), particularly on fine sand (par6cle diameter of 250 ㎛). Internal morphology and in situ observations on their feeding habit indicated that A. manni is a deposit feeder, feeding on organic debris contained in the sediment around its habitat A. manni were more frequently observed near Zostrea marina bed where content of organic matter in the sediment is considered to be higher. Gonadal tissues of the male were yellow in color while female gonads appeared to be purple. Fully mature eggs, with a mean diameter of 381㎛, and sperm were observed from the histological slides of the sand dollars collected in late July to August, suggesting that A. manni spawn during July to August when water temperature reaches 20 to 25℃

4성분계 다중반응증류 공정의 시각화

강도형 ( Do Hyung Kang ),이재우 ( Jae W. Lee ) 한국화학공학회 2014 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.52 No.6

4성분계 다중반응이 반응증류 탑 내에서 발생할 때 증류거동의 변화를 시각화 방법을 통해 분석하였다. 시각화 방법이란 단순 증류의 물질수지에 각 반응에 의한 벡터를 추가하고 이를 공간상에 표현하는 것으로 각 단에서 혼합물의 조성 변화 및 반응의 진척도를 직관적으로 알 수 있다. 또한 이를 통해 주어진 운전조건에서 필요한 총 단수 및 최적반응 단의 위치를 결정할 수 있다. 본 연구에서는 에틸렌글리콜(Ethylene glycol) 생산공정을 시각화 방법을 통해 분석하였다. 제안된 시각화 방법을 사용하여 복잡한 실험이나 공정모사 없이 4성분계 다중반응증류 공정에 대한 타당성 평가 및 분석이 가능하다. When multiple reactions of quaternary mixtures take place in a reactive distillation column, the behavior of composition trajectory is analyzed by a visual-aided method. By adding additional vectors of multiple reactions and visualizing them in composition space, the composition of each component and extent of each reaction on an arbitrary stage can be easily estimated in terms of the composition trajectory and reaction cascade difference points. Moreover, for a given operating conditions, the number of total stages and position of optimum reaction zone can be determined by the visual-aided method. In this study, ethylene glycol synthesis with a side reaction is taken as an example and analyzed by the proposed graphical method. Through this method, the quaternary reactive distillation with multiple reactions can be analyzed without numerous experiments and simulations.

제주도 종달리 체험어장의 환경적 특성과 발전 방향

강도형(Do Hyung Kang),양승식(Seung Sik Yang),최광식(Kwang Sik Choi),조성윤(Sung Yun Cho),제종길(Jong Gil Je) 제주학회 2000 濟州島硏究 Vol.18 No.-

다(多)출력 DC-DC 플라이백 컨버터용 변압기 설계방법 및 개발

박종연,강도형,Park, Jong Yeon,Kang, Do Hyung 강원대학교 산업기술연구소 2000 産業技術硏究 Vol.20 No.1

This paper gives a fundamental study of the design method of Flyback Transformer(FBT) in the Multioutput Flyback DC-DC Converter. We explained a winding strategy and Core selecting of the Flyback transformer to get the design guidelines for optimizing the performance of Flyback DC-DC Converter. The final goal of this paper is to obtain design rules of the Flyback transformer to minimize the leakage inductance for good quality of DC Souce.

바이오피드백을 이용하여 측정한 만성통증 환자의 정신생리적 특징

이진성,강도형,안현주,윤대현,정도언,Lee, Jin-Seong,Kang, Do-Hyung,An, Hyun-Ju,Yoon, Dae-Hyun,Jeong, Do-Un 대한수면의학회 2009 수면·정신생리 Vol.16 No.2

Objectives: Chronic pain is one of the most common experiences of humans and a typical psychophysiological disorder. The aim of this study was to measure the psychophysiological responses in chronic pain patients using a biofeedback system, and to compare them with the results from normal healthy subjects. Methods: Forty two patients with chronic pain (17 males and 25 females, average age $44.67{\pm}11.10$ years) and 42 normal healthy controls (17 males and 25 females, average age $45.17{\pm}10.46$ years) participated in this study. Electromyography (EMG), skin conductance (SC), and skin temperature (ST) were recorded using biofeedback system during the 3 phases (baseline, stress, and recovery) of stress reactivity test, and average values of them were calculated. Difference of values between two groups in each corresponding phase was analyzed with independent t-test, and change of values across phases of stress reactivity test was analyzed with paired t-test (all two-tailed, p<0.05). Results: Compared to normal controls, chronic pain patients had higher value of EMG (baseline: $8.10{\pm}5.97{\mu}V$ vs $4.72{\pm}1.52{\mu}V$, t=-3.56, p<0.01; stress: $11.25{\pm}6.89{\mu}V$ vs $8.49{\pm}4.78{\mu}V$, t=-2.13, p<0.05; recovery: $7.12{\pm}3.77{\mu}V$ vs $4.78{\pm}1.59{\mu}V$, t=-3.70, p<0.01) and SC (baseline: $1.06{\pm}1.0{\mu}S$ vs $0.42{\pm}0.29{\mu}S$, t=-4.0. p<0.01; stress: $1.87{\pm}2.05{\mu}S$ vs $1.03{\pm}0.86{\mu}S$, t=-2.47, p<0.05; recovery: $1.74{\pm}1.77{\mu}S$ vs $0.64{\pm}0.59{\mu}S$, t=-3.8, p<0.01) in all the 3 phases. But, skin temperature comparison did not reveal significant differences in all the 3 phases between two groups. Conclusion: Psychophysiological responses of chronic pain patients in stress reactivity test were different from those of normal healthy controls. These results suggest that sympathetic nervous system is more activated in chronic pain patients. 목 적: 바이오피드백은 정신생리연구에서 중요한 위치에 있으며 정신생리장애 치료에도 유용하다. 만성통증은 매우 흔히 관찰되는 대표적 정신생리장애이다. 이 연구에서는 바이오피드백 기기를 이용한 스트레스 반응 검사로 만성통증 환자와 정상인 간에 생리신호의 특성을 비교하였다. 방 법: 만성통증 환자 42명(남자 17명, 여자 25명, 44.67${\pm}11.10$세)에게 치료 첫째 시간에 바이오피드백 기기를 이용하여 스트레스 반응검사를 하였다. 그 결과를 정상인 42명(남자 17명, 여자 25명, 45.17${\pm}10.46$세)과 비교하였다. 스트레스 반응검사에서는 기저, 스트레스, 그리고 회복 상태에서 각각 전두근 근전도(frontalis electromyography), 피부전도(skin conductance), 피부체온(skin temperature)을 각각 2분씩 측정하여 평균값을 산출하였다. 측정값들의 양 군간 비교에는 독립 t-검정(independent t-test), 각 상태에 따른 측정값의 변화는 대응표본 t-검정(paired-test)로 분석하였다(양측검정, p<0.05). 결 과: 만성 통증 환자는 정상인에 비해 기저, 스트레스, 그리고 회복 상태 모두에서 전두근이 더 긴장해 있었다 (기저: $8.10{\pm}10.465.97{\mu}V$ vs $4.72{\pm}1.52{\mu}V$, t=-3.56, p<0.01; 스트레스: $11.25{\pm}6.89{\mu}V$ vs $8.49{\pm}4.78{\mu}V$, t=-2.13, p<0.05; 회복: $7.12{\pm}3.77{\mu}V$ vs $4.78{\pm}1.59{\mu}V$, t= -3.70, p<0.01). 또한 만성 통증 환자는 세 상태 모두에서 피부전도가 더 잘 되었다(기저: $1.06{\pm}1.0{\mu}S$ vs $0.42{\pm}0.29{\mu}S$, t=-4.0. p<0.01; 스트레스: $1.87{\pm}2.05{\mu}S$ vs $1.03{\pm}0.86{\mu}S$, t=-2.47, p<0.05; 회복: $1.74{\pm}1.77{\mu}S$ vs $0.64{\pm}0.59{\mu}S$, t=-3.8, p<0.01). 그러나 피부체온은 기저, 스트레스, 그리고 회복 상태 모두에서 두 군 사이에 유의한 차이가 없었다(p<0.05). 결 론: 만성 통증 환자는 정상인에 비해 전두근 근전도와 피부전도 측정값이 전반적으로 증가된 소견을 보였다. 이는 통증으로 인하여 교감신경계가 정상인에 비해 자극에 더 예민한 상태에 있음을 시사한다.

강박장애 환자에서의 안와전두피질 용적의 2년 추적 연구

김성년,강도형,유소영,노규식,장준환,최정석,하태현,권준수,Kim, Sung-Nyun,Kang, Do-Hyung,Yoo, So-Young,Roh, Kyu-Sik,Chang, Joon-Hwan,Choi, Jung-Seok,Ha, Tae-Hyon,Kwon, Jun-Soo 대한불안의학회 2006 대한불안의학회지 Vol.2 No.2

Objective : This study was designed to examine the volumetric abnormality of orbitofrontal cortex (OFC) and its change after 2 years of pharmacotherapy in obsessive compulsive disorder (OCD) patients. Method : Volumetric magnetic resonance imaging studies were conducted in 15 OCD patients and 13 normal volunteers. For 2 years, all patients took at least one serotonin reuptake inhibitor and atypical antipsychotics were used as an augmentation therapy in most patients. The follow-up MRI studies were conducted after the pharmacotherapy and OFC volumes were measured by the manual region of interest method. Results : Bilateral OFC volumes of 15 OCD patients were significantly greater than those of the normal volunteers before the treatment. After 2 years of the treatment, significant decrease was observed in bilateral OFC volumes of OCD patients to the extent that left OFC volume of OCD patients was not different from that of the normal volunteers. Conclusion : This finding suggests that OFC is directly related to the pathophysiology of obsessive compulsive disorder.

정신분열병 환자에서 40Hz 뇌 사건관련전위에 관한 연구 : 분석 방법론적 측면

윤탁,박해정,강도형,김명선,김재진,권준수,Youn, Tak,Park, Hae-Jeong,Kang, Do-Hyung,Kim, Myung-Sun,Kim, Jae-Jin,Kwon, Jun Soo 대한생물정신의학회 2001 생물정신의학 Vol.8 No.2

Backgrounds : Gamma band oscillatory activity is considered to be related to cognitive functions and illustrates that the concept of event-related oscillations bridges the gap between single neurons and neural assemblies. An event-related gamma oscillation is the time-locked responses of specific frequency, and can be identified by computing the amplitude frequency characteristics of the averaged event-related potentials(ERPs) after stimulation. Objectives : We purposed to present experimental paradigm to investigate ${\gamma}$-band oscillation activities from the recording of ERPs by using auditory oddball paradigm and investigate the difference of ${\gamma}$-band activity between schizophrenia and normal controls. Methods : The ERPs resulting from auditory stimuli with oddball paradigm in a group of schizophrenics(n=11), and also a group of age-, sex-, and handedness matched normal controls, were recorded by 128 channel EEG. The ${\gamma}$-band oscillatory activities were calculated by using time-frequency wavelet decomposition of the signal between 20 and 80Hz. The ${\gamma}$-band oscillatory activities of both groups were compared by t-test. Results : The ${\gamma}$-band oscillatory of the leads Fz, Cz, and Pz of both groups were represented well in the time-frequency maps. Significant increases of the ${\gamma}$-band activity in normal controls compared with schizophrenics were observed around 160 msec, 350 msec, and 800 msec after stimulation. Conclusions : Our results suggested that the increment in ${\gamma}$-band oscillatory activity during cognitive operations and decreased ${\gamma}$-band activity in schizophrenics may be associated with the cognitive dysfunctions and the pathophysiology of the schizophrenia.

강박증 이환기간과 임상 양상

이승재,유소영,강도형,권준수,Lee, Seung-Jae,Yoo, So-Young,Kang, Do-Hyung,Kwon, Jun-Soo 대한불안의학회 2006 대한불안의학회지 Vol.2 No.1

Objectives : There is a paucity of data on the long-term course of obsessive-compulsive disorder (OCD) and chronological relationship between OC symptoms and their related symptoms such as anxiety and depression. The purpose of this study was to investigate the longitudinal course of OC symptoms as well as anxiety and depression which are believed to be associated with OC symptoms. Methods : Data for 155 patients with OCD who completed general evaluation for OCD were used. Forty four were excluded to minimize the effect of the different age of onset on the clinical course. One hundred eleven patients finally participated in the analysis. Cross-sectional correlations between each symptom as well as between such symptoms and the duration of illness were analyzed. Further correlation analysis was done within two groups that were divided by 7 years of the duration of illness. Results : There were significant correlations not only between the severity of OC symptoms and anxiety but also between anxiety and depressive symptom, regardless of the duration of illness. These correlations between such symptoms were also found within patients with the duration of illness below 7 years, whereas these were not within the group with the duration of illness above 8 years. Conclusion : Patients with OCD in this study shows the moderate to severe level of OC symptoms irrespective of the duration of illness. Our finding also suggests that the OC symptoms, especially obsessions are closely related to anxiety and depressive symptoms and these relationships might be pronounced in relatively early phase of the OCD after onset.

多출력 DC-DC 플라이백 컨버터용 변압기 설계방법 및 개발

박종연(Park Jong Yeon),강도형(Kang Do Hyung) 강원대학교 산업기술연구소 2000 産業技術硏究 Vol.20 No.1

This paper gives a fundamental study of the design method of Flyback Transformer(FBT) in the Multioutput Flyback DC-DC Converter. We explained a winding strategy and Core selecting of the Flyback transformer to get the design guidelines for optimizing the performance of Flyback DC-DC Converter. The final goal of this paper is to obtain design rules of the Flyback transformer to minimize the leakage inductance for good quality of DC Souce.