진부지역에서 생산된 당귀를 이용한 추출물 제조 및 이화학적 특성

이원종,윤정로,김은경,안규태 강릉대학교 동해안지역연구소 2000 東海岸硏究 Vol.11 No.1

추출조건 (온도, 추출시간, 용매의 농도)에 따라 당귀의 특유성분인 decursin의 함량을 측정하였으며, 산지별로 당귀를 수집하여 추출물을 제조한 후 이화학적 성질을 조사하였다. 물, ethanol, methanol, chloroform, benzene, ether등으로 추출한 결과, 당귀의 지표물질인 decursin은 물로는 잘 추출되지 않았고 고농도의 ethanol로 추출하는 것이 가장 효과적이었다. 당귀의 ethanol 추출물 제조시 ethanol의 농도는 95%, 추출온도는 60℃, 추출시간은 4시간이 가장 적합하였다. 진부지역에서 생산된 일당귀 및 일본산 당귀의 decursin 함량은 0.2-0.5%이었고, 중국산 당귀는 1.1%를 함유하였으며 진부산 토당귀는 6.2%를 함유하였다. 진부산 토당귀와 일당귀, 중국산, 일본산 당귀를 열수 추출물, ethanol 추출물을 제조한 결과, 열수 추출물은 ethanol 추출물보다 단백질과 회분을 많이 함유하였으며, ethanol 추출물은 지질을 많이 함유하였다. Chemical components and decursin contents of Angelica gigas Nakai (Korean), Angelica acutiloba Kitagawa (Korean and Japanese), and Angelica sinensis Diels (Chinese) were analyzed. Angelica gigas Nakai (Korean) contained the highest amount of decursin with 6.2%, while Angelica acutiloba Kitagawa (Korean and Japanese) contained only 0.2-0.5% decursin and Angelica sinensis Diels (Chinese) contained 1.1% decursin. Angelica gigas Nakai (Korean) was extracted under various conditions and evaluated for decursin content. The decursin content of extracts was the highest when extracted with 95% ethanol at 60℃ for 4 hours. Angelica gigas Nakai was extracted with water and 95% ethanol and physicochemical properties of extract were analyzed, The extraction yield. protein content, and ash content were high when using the water as an extraction solvent; while, crude lipid was high when using the 95% ethanol as the extraction solvent.

성인 여성의 자궁경부암 및 유방암 조기검진 수검행위에 영향을 미치는 요인

노윤녕,김영복,박용문,이원철,맹광호 韓國保健敎育.健康增進學會 2000 보건교육건강증진학회지 Vol.17 No.1

This study was aimed at preparing basic dada required for establishment of a cancer screening program by examining the status of cancer screenings performed by women in a city and the factors that had an influence on cervical and breast cancers screening behavior of women. In order to find out the status of cervical and breast cancers screening and the factors having an influence on cervical and breast cancers screening behavior, 1,113 women were selected as study area and subjects by a random cluster sampling method, and the subjects were answered by questionnaires. The major results were as follows. 1.In the cases of the breast and the cervical cancers, 16.7% and 55.7% of the subjects turned out to have had one or more screenings respectively in their life-time. Also the rate of screening group of cervical and breast cancers was 16.7%, the rate of screening group of only cervical cancer was 38.9%, and the rate of non-screening group was 44.4%. 2.As to the screening pattern of cervical and breast cancer, there were significantly for age, income, occupation, married status, spouse, the factors associated with health promotion (doctor visiting, exercising), married age, number of children, and breast feeding(p〈0.05). 3.The factors associated with screening behaviors for cervical and breast cancers were age, income, occupation, married status, doctor visiting, exercising, married age, number of children, and breast feeding(p〈0.05). Based on the above-mentioned results obtained by this study, it was anticipated that this study may be play a vital role as basic data for the development and execution of cervical and breast cancers screening program for women in a community. And the analysis, done on the basis of the status of the cancer screening, of the influence factors on cervical and breast cancers screening behavior showed that for the development of a cancer screening program, the factors like age, social-economic class, married status, health promotion behavior, and reproductive characteristics should be considered.

후천성 면역 결핍증 환자의 혀에 발생한 거대세포바이러스(CMV : cytomegalovirus) 감염

송노헌,이종호,정필훈,김명진,김수경,남일우,김종원,백세미,홍삼표 大韓顎顔面成形再建外科學會 1998 Maxillofacial Plastic Reconstructive Surgery Vol.20 No.1

방사성 동위체 도입과 그 추적기술에 의한 수도계(水稻系) 활성상의 해명과 개선에 관한 연구(제3보) : 저인산성 무기 용성물질의 시용과 용수조절 효과에 대하여 Effects of Application of Fused Magnesium Low Level Phosphate and Control of Irrigation Water

이춘영,안학수,정희돈,김규원,노준정 한국농화학회 1973 Applied Biological Chemistry (Appl Biol Chem) Vol.16 No.1

1. Through out the entire stage of growth, the amount of nutrients, number of tillers and of spikes increased in the Simagcalin treated plot as compared with the control. The treated plot showed healthul growth at the later growing stage. On the other hand. management of irrigation water resulted in raised the grain straw ratio and retarded the culm height about 10%. 2. Application of Simagcalin greatly increased the content of phosphorus and magnesium at the harvesting time. The culm and sheath analyses are recommendable for the determination of magnesium deficiency. 3. The controled irrigation would effect root activity as the main factor, and Simagcalin might act as a secondary factor. 4. While the application of phosphorus may not affect the yield components, The basic elements in Simagcalin may enhance the uptake ov nutrients under heavy application of nitrogn.

응고제로서 해수사용이 두부의 물리적 특성에 미치는 영향

이원종,윤정로 강릉대학교동해안지역연구소 1997 東海岸硏究 Vol.7 No.2

응고제로서 해수의 사용이 제조된 두부의 물리적 특성에 미치는 영향을 비교하였다. 해수 사용시의 두부의 수분함량은 다른 응고제 사용시보다 높았고 이것이 제조된 두부의 부드러운 조직에 영향을 끼치는 것으로 추정되었다. 또한 해수를 사용한 두부는 부드러운 가운데서도 결착성이 좋았다. 압착도를 달리하여 두부를 제조하였을 때 압착도가 증가함에 따라 두부의 수분 함량 및 수율은 감소하였고 경도는 증가하였다. 관능검사 결과 전체적인 기호도는 ??,??,?? 의 순으로 최적압착도에서의 압착을 통한 적정 경도 유지가 중요함을 알 수 있었다. 제조된 두부의 경우 경도는 수분함량이 높을수록 또 섬유질의 함량이 낮을수록 감소하였다. In this study, sea water was compared with several conventional coagulants (calcium chloride, calcium sulfate, magnesium chloride and gluconodeltalalactone) in its effect on the physical properties of tofu coagulated with it. Chodang tofu (coagulated with sea water) was highest in the moisture content and this made the texture of tofu soft. Moreover, Chodang tofu was not only soft but also cohesive. As the molding pressure was increased, the moisture content and the yield of tofu were decreased but the hardness was increased. As far as molding pressure is concerned, sensory evaluatin indicated that the overall preference of tofu was in the order of ??, ?? and ??. The hardness of Chodang tofu was lower with its higher moisture content and with lower fiber content.

헌체운동의 새 방향

김원식,이영호,김수일,양태창,한승로 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

We analyzed the 10-year outcomes of the Daejon-Chungnam Center for Cadaver Donation Movement from May 1, 1993 to February 28, 2002, and obtained the following results. 1. The main products of 10-year cadaver donation movement were the significant increment of the number of registered donators, especially those of the women, the change of the civic consciousness on cadaver donation, and reports on the anatomic and teratologic studies. 2. The leading problems of the cadaver donation movement were the non-fresh cadaver experiment, lack of exclusive responsible post, personnel and budget, lack of non-medical cadaver practices, and the absence of donation of child and fetus cadavers. From the above results, it is considered that the on-going cadaver donation movement should be emphasized on the following subjects, (1) practical use of the cadavers for the non-anatomical education and research, such as clinically related study, preservative education of surgical practitioners, and observation and training of non-medical personnel, (2) practical use of organs and tissues of cadavers as the remedy materials, such as transplantation and cuture of viable organs, tissues or cells, (3) early donation is essential to obtain the fresh cadaver, and the revision of the legal proceedings to solve the ethic problems is needed, (4) and the local administrative post exclusive responsible post for the public information of cadaver donation and management of registered persons is needed to be established, and the enhancement of relationship of the all local medical and non-medical colleges.

석탄회를 이용한 제올라이트의 합성과 중금속 흡착 특성

류완호,이원묵,홍필선,양천희,안재영,백일현,이병노 한국화학공학회 2003 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.41 No.5

석탄회를 이용, 중금속 제거용 흡착제 제조를 목적으로 NaOH를 반응물로 한 수열합성 반응으로 제올라이트를 합성하였으며, 이에 대한 성능특성 및 중금속 흡착실험을 수행하였다. SiO₂와 Al₂O₃를 주성분으로 한 석탄회를 NaOH에 의한 수열합성 반응으로 폐수 중에 포함되어 있는 중금속에 대한 제거능력이 높은 제올라이트를 합성하고자 하였다. 따라서 NaOH 농도, 시간을 변화시키면서 제올라이트를 합성하여 실험한 결과 4 M-NaOH, 4시간에서 최적의 조업조건을 얻을 수 있었다. 산에 의한 전처리 과정을 거친 합성 제올라이트는 pH 7-9.5로 중성을 나타내었다. 또한 산처리 합성 제올라이트를 이용하여 중금속인 P, Pb, Cd, Cr, Mn등의 흡착능을 비교한 결과 P, Pb, Cd 등은 비교적 흡착능이 우수하게 나타났지만 Cr과 Mn 등은 pH가 너무 높기 때문에 거의 흡착이 이루어지지 않았다. Zeolite was synthesized from coal fly ash produced by a domestic power plant and has applications in the removal of heavy metal from waste water. Zeolite was synthesized using a hydrothermal method involving an alkaline reaction with NaOH. The NaOH concentration and reaction times were varied in order to synthesize zeolite showing the maximum removal efficiency of heavy metal from waste water. The synthesis conditions were optimized at the concentration of 4M-NaOH and the reaction time of 4hn. The synthesized zeolite needed washing with HCI solution to improve the removal efficiency of P, Pb. Cd. Cr. Mn and it was maximized at pH 7-9.5 in leaching solution of synthesized zeolite.

임상가검물에서 분리된 효모의 임상적 의의

유병용,이원길,김재식,전효진,노략균,이장백,김중명 慶北大學校 醫科大學 1990 慶北醫大誌 Vol.31 No.4

1988년 1월부터 동년 12월말까지 경북대학교병원 임상병리과에 의뢰된 가검물 중에서 효모가 분리되었던 환자는 159명이었고, 남자와 여자의 비율은 1.8이었으며 1세 이하와 30세 이상에서 많았다. 또 분리 동정된 효모 총 159주 중 객담에서 78주(49.1%), 요에서 64주(40.3%), 복막액 5주(3.1%) 편도와 대변 각각 4주(2.5%), 농에서 3주(1.9%) 뇌척수액에서 1주(0.6%) 순으로 분리되었다. 분리된 효모로는 Candida albicans가 68주(42.8%), Candida tropicalis 33주(20.8%) Torulopsis glabrata 20주(12.6%), Candida parapsilosis 17주(10.7%), Trichosporon beigelli 7주(4.4%), Torulopsis candida 5주(3.1%), Torulopsis inconspicua와 Saccharomyces cerevisiae가 각 4주(2.5%), Candida guilliermondii 1주(0.6%) 순으로 있었다. 환자들의 기존질병은 폐질환이 70예, 요로질환이 40예 악성종양 및 당뇨병이 각 22예, 간질환 16예, 순환기 질환이 12예 등으로 나타났으며, 유인중 항생제 사용은 114예(80.0%), 수술 49예(34.3%), 카테터 46예(32.2%), 스테로이드사용 28예(19.6%) 악성종양과 당뇨병이 22예(15.4%), 항암제 사용이 10예(7.0%)로 나타났다. 유인이 2개 중복된 경우는 43예, 3개 중복은 38예, 4개는 11예, 5개는 2예로 나타났다. Yeast infection is commonest fungal infection of human. And their incidence becomes to be increased as the frequency of altered host immune system is increased. Antibiotics, cytotoxic drug, malignancy, diabetes mellitus, operative procedures and catherizations are predisposition of fungal infection. Since antifungal drug within a selective or narrow range of activity are available, it is important that speciation of yeast in routine clinical microbiology practice should be effected rapidly and reliably. Author isolated 159 strains of yeast and that were identified by API 20C Auxanogram®. Patient charts were reviewed retrogradely in order to find predisposing factors of isolated yeast cells. Yeast isolation is 1.8(102:57) of male to female rtio and is more frequently below 1 year-old and above 30 year-old in both sexes. Septum(49.1%). urine(40.3%) were major specimens in which yeast isolated. Candida albicans(42.8%), Candida tropicalis(20.8%), Torulopsis glabrata(12.6%), Candida parapsilosis(10.7%) were frequently identified species in order. Candida albicans and Candida parapsilosis were frequently isolated species among various specimens. Pulmonary diseases, urinary tract diseases, malignancy, and diabetes mellitus were major underlying diseases. And antibiotic(80.0%), operative procedure(34.3%), catherterization(32.2%), steroid(19.6%), malignancy(15.4%), diabetes mellitus(15.4%) and cytotoxic drug(7.0%) were predisposed in order.

Melandrin의 방향족 유도체 합성에 관한 연구

임중기,이강노,함원훈,이상인 성균관대학교 약학연구소 1992 成均藥硏論文集 Vol.4 No.1

Melandrin, as a possible phytoalexin, which is expected to have the various pharmacological activities; antibacterial, antifungal and antiviral activity, was isolated in 1987 by Woo from Melandrin firmum (Caryophyllaceae). The synthesis of melandrin derivatives has been accomplished by the reaction of 5-hydroxy anthranilic acid ethyl ester with acid chlorides and then by hydrolysis of ethyl ester.

Angiotensin Concerting Enzyme 유전자의 유전적 다형성(Genetic Polymorphism)이 관상동맥 질환 위험인자에 따른 혈중 Plasminogen Activator Inhibitor-1의 농도에 미치는 영향

김덕경,김종원,권현절,류재춘,박승우,김준수,이상훈,홍경표,박정의,이원로 대한고혈압학회 1996 대한고혈압학회지 Vol.2 No.2