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金熙鍾,柳又秀,金佳鉉,申東守,韓健模,全裕燦 東亞大學校 大學院 1984 大學院論文集 Vol.9 No.-
This paper is a study on relation between run-off ratio and antecedent discharge, run-off ratio and antecedent discharge per unit area, antecedent discharge and antecedent precipitation, by the data from the five major river basins in Korea and the small river basins in Pusan. The Nak-Dong rivers(An-Dong upper stream) f=0.4780+0.0124 ln qA r=0.99 qA=0.3368e0.1101R r=0.99 f=0.5793+0.0146 ln(qA/A) r=0.99 The Nak-Dong rivers except Ga-song station f=0.2017-0.0840 ln qA r=0.75 f=0.7012+0.0750 ln(aA/A) r=0.71 The Han rivers f=-0.0035+01267 on qA r=0.75 f=1.1311+0.1263 ln(qA/A) r=0.71 L=302.9064-43.8490 ln qA r=0.84 The Geun rivers(Mu-sin Cheon) f=0.295+0.1823 ln qA r=0.93 f=0.8417+0.1823 ln(qA/A) r=0.93 L=40.0456+62.0346 ln qA r=0.94 The Yeong-san rivers f=0.3766+0.0598 ln qA r=0.79 f=0.8084+0.0599 ln(qA/A) r=0.79 The Seom-jin rivers f=-1.3875+0.6505 ln qA r=0.92 f=2.1633+0.3465 ln(qA/A) r=0.76 Small river basin in Pusan f=0.3635+0.1120 ln qA r=0.87
서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)
김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2
Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.
중풍(中風) 환자(患者) 중(中) 언어장애(言語障碍)에 대한 임상적(臨床的) 고찰(考察)
신우진,서수현,홍현우,이성도,김재연,감철우,박동일,Shin, Woo-Jin,Seo, Soo-Hyun,Hong, Hyun-Woo,Lee, Sung-Do,Kim, Jae-Yun,Kam, Chul-Woo,Park, Dong-Il 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.3
This clinical study on 93 cases of Dyslogia after stroke confirmed through brain CT, MRI scan and clinical observation. They were hospitalized in the oriental medical hospital of Dong-Eui University from january to September 2003. The following results were found: I. The ratio between males and females was 1.6:1. Of Dyslogia p who had suffered stroke, most were in their sixties. 2. Categorized by attack site, right hemiplegia patients comprised 15 cases(l6.1%), and left hemiplegia patients, 71 cases(54.8%), so the ratio between Rt. and Lt. was 1:4.7. 3. Categorized by preceeding disease, hypertension was seen 51 cases(54.8%), and diabetes mellitus was seen 21 cases(22.6%). 4. Categorized by repeat attack, it was the first attack for 71 cases(76.3%), and the second attack for 13 cases(l4.0%), and for 9 cases(9.7%) it was the third or nth attack. 5. According to the classification of Zhang Zhongjing, apoplexy involving Bu-organs comprised 42 cases(45.2%), apoplexy involving meridians 39 cases(41.9%), apoplexy involving Jang-organs 11 cases(11.8%), and for apoplexy involving collaaterals there was one case(1.1%). 6. According to the classification of Cheng Zhongling, 43 cases(46.7%) were classed heart meridian, 25 cases(27.2%) were classed Spleen meridian, and 24 cases(26. 1%) were classed Kidney meridian. 7. According to the classification of Sun Simiao, 49 cases(52.7%) were classed Pyungo, two cases(2.2%) were classed Pungeui, ,seven cases(7.5%) were classed Pungbi( I ), and two cases(2.2%) were classed Pungbi( II ).
우지수,한동철 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.1
Background : Actin disassembly is one of the main pathogenic phenomena in diabetic nephropathy. Small GTPases, related with actin cytoskeleton, may have a pathogenic role in high glucose (HG) induced renal injury. Methods : HG-stimulated gene profiling in cultured human glomerular endothelial cells (GEC) was examined by using oligonucleotide microarray technique. Human GEC were isolated from normal part of nephrectomy specimen and cultured under normal glucose (5.6 mM) or HG (30 mM) for 24 h, 48 h and 72 h. Total RNA was purified from the cell and then applied on 10 K-DNA chip (Macrogen) after amplified with T7 RNA polymerase. Results : About 2,400 genes showed 2-fold difference by HG. Approximately, 300 out of 2,400 genes were down-regulated and about 460 genes were up-regulated continuously by HG. Rho GTPase-related molecules and actin cytoskeleton regulatory gene expressions were highly regulated. Rho7, Rho guanine nucleotide exchange factor 1 and 3, and Rho GDP dissociation inhibitor were significantly up-regulated by HG without alteration of Rho GTPase activation protein 5, suggesting increased activity of Rho GTPase. In addition, myosin light chain 2 and 3, and p21-activated kinase, possibly related with actin-myosin interaction, were also significantly up-regulated by HG. Western blot revealed HG induced increase of CDC42 protein expression, not RhoA and Rac1 in total cell lysates of GEC. Conclusion : Enhanced gene profile encoding Rho GTPase and actin cytoskeleton is one of prominent components of the GEC transcriptomic response under HG.
이탈리안 라이그래스의 성숙종자 유래 캘러스로부터 효율적인 식물체 재분화
우현숙,이상훈,이동기,김진수,원성혜,이병현 Plant molecular biology and biotechnology research 2004 Plant molecular biology and biotechnology research Vol.2004 No.-
As an initial step for future genetic manipulations to improve forage characteristics of Italian ryegrass (Lolium multiflorum Lam.), an efficient tissue culture system was established and the factors affecting plant regeneration were evaluated. MS medium containing 5 ㎎/L 2,4-D was optimal for embryogenic callus induction from mature seed and had a strong effect on successive plant regeneration. The plant regeneration frequency was observed at above 70% when embryogenic calli induced were transferred to N6 medium supplemented with 1 ㎎/L 2,4-D and 5 ㎎/L BA. Among several basic media tested, MS and M6 medium were optimal for callus induction and plant regeneration, respectively. Genotype was an important factor in plant regenerability. 'Jeanne' showed the highest regeneration frequency of 73%. A short tissue culture period and high-frequency regeneration system established in this study will be useful for molecular breeding of Italian ryegrass through genetic transformation.
우숙희,정국동,최송표,조근자,양은진,김수일,박경란,이영호,김원식 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1
Fingerprint patterns of 333 schizophreniacs who met with the diagnostic criterias of International Pilot Study of Schizophrenia except items associated with chronicity in exclusion criteria were studied, and the following results were obtained. 1. The frequency distribution of the fingerprint patterns in the 333 schizophreniacs was ulnar loop, whorl, twinned loop, arch, radial loop in order in both control and schizophrenia groups. 2. Finger ridge counts of both sexes were decreased significantly in schizophrenia group. 3. Dissociation of fingerprint pattern in the schizophrenia group was 51.1%, which was far greater than 6.25% of control group. Number of dissociation was greatest in the thumb, followed by index, middle, ring, and little finger in order. According to the above results, it is considered that both the number of finger ridges and degree of dissociation of fingerprint patterns were closely related with schizophrenia. Analysis of fingerprints and palmprints with the aid of chromosomal analysis would contribute the early diagnosis and prevention of schizophrenia.
새로운 Baculoviurs 전이벡터를 이용한 Escherichia coli β-galactosidase 유전자의 발현
우수동,김우진,김혜성,진병래,강석권 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.1
국내에서 분리된 BmNPV를 이용하여 제작된 새로운 전이벡터 pBmKSK1에 외래 유전자로서 E. coli lacZ 유전자를 클로닝하고 재조합 바이러스를 제작하였다. 재조합 바이러스에 대하여 Southern blotting 분석을 실시하여 lacZ 유전자의 존재를 확인하였으며, 재조합 바이러스가 접종된 세포의 SDS-PAGE 및 Western blotting 분석을 통하여 β-galactosidase의 발현을 확인하였다. 재조합 바이러스의 발현효율을 누에 세포주 및 유충에서 비교 조사한 결과, 유충에서 더욱 높은 발현량을 보임을 확인하였다. To investigate the expression efficiency of new transfer vector of Bombyx mori nuclear polyhedrosis virus (BmNPV), Escherichia coli lacZ gene was inserted into new transfer vector pBmKSK1, under the control of polyhedrin promoter and expressed in BmN-4 cells coninfected with transfer vector pBmKSK1-LacZ and vild type BmNPV genome, and analysed by Southern blotting. The expression of β-galactosidase was characterized by SDS-PAGE, Western blotting and β-galactosidase activity assay. The results showed that the level of expression in silkworn larvae was higher than that of BmN-4 cells.
Shrinkage Estimation of Parameters in a Linear Model
禹正秀,金東郁 嶺南大學校附設 基礎科學硏究所 1984 基礎科學硏究 Vol.4 No.-
In this paper we shall propose shrinkage estimator in a linear model. We shall find the condition that can be used in seeking the situations in which proposed estimator is superior to the least square estimator.