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이희삼,정교순,김선여,류강선,이완주 한국잠사학회 1998 한국잠사곤충학회지 Vol.40 No.1
This study was designed to investigate the blood glucose lowering effect of sericultural products using alloxan-induced hyperglycemic mice. The administration of sericultural products did not affect body weight between normal mice and alloxan induced hyperglycemic mice. High blood glucose level in alloxan-induced mice group was maintained, during all the experimental period. In the 2-3 weeks, a significant decrease in the blood glucose level was observed in the group treated with sericultural products. Up to 5 weeks, blood glucose level of those group was maintained. Sericultural products treatment group have a activity for glucose tolerance test Sericultural products showed the blood glucose lowering activity for loading maltose and sucrose.
송강일,추준욱,서준교,최귀원,유선국,윤인찬,Song, Kang-Il,Chu, Jun-Uk,Suh, Jun-Kyo Francis,Choi, Kui-Won,Yoo, Sun-K.,Youn, In-Chan 대한의용생체공학회 2011 의공학회지 Vol.32 No.1
Cuff electrodes have a benefit for chronic electroneurogram(ENG) recording while minimizing nerve damage. However, the ENG signals are usually contaminated by electromyogram(EMG) activity from the surrounding muscle, the thermal noise generated within the source resistance, and the electric noise generated primarily at the first stage of the amplifier. This paper proposes a new cuff electrode to reduce the interference of EMG signals. An additional middle electrode was placed at the center of cuff electrode. As a result, the proposed cuff electrode achieved a higher signal-to-interference ratio compared to the conventional tripolar cuff. The cuff electrode was then assembled together with closure, headstage, and hermetic case including electronic circuits. This paper also presents a lownoise amplifier system to improve signal-to-noise ratio. The circuit was designed based on the noise analysis to minimize the electronic noise. The result shows that the total noise of the amplifier was below $1{\mu}V_{rms}$ for a cuff impedance of $1\;k{\Omega}$ and the common-mode rejection ratio was 115 dB at 1 kHz. In the current study, the performance of nerve cuff electrode system was evaluated by monitoring afferent nerve signals under mechanical stimuli in a rat animal model.