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기능성 소화불량증환자에서 Winstal® 투여에 관한 임상경험
이창형,김영탁,금민수,권중구,안병철,윤영미,권영오,김성국,최용환,정준모 慶北大學校 醫科大學 1994 慶北醫大誌 Vol.35 No.3
목적 : 기능성 소화불량증은 소화, 흡수등 장관의 기능적인 이상과 관련되어 있을 것으로 생각되며 복합소화효소제(Winstal®)를 투여하여 그 임상효과를 평가하고자 본 연구를 실시하였다. 대상 및 방법 : 1994년 3월 부터 6월까지 경북대학교병원 내과를 방문한 기능성 소화불량증을 호소하는 환자 20명을 대상으로 Winstal®을 1회 1정씩, 1일 3회 식후 30분내에 경구로 2주간 투여하였다. 결과 : 소화불량증의 증상은 복부불쾌감, 복부팽만감, 식욕부진 및 오심, 복부동통, 공기연하증, 고창 및 구토순이었으며, 증상의 개선은 복부불쾌감이 76.4%(13/17)로 가장 높았으며, 그 다음으로 복부팽만감 및 공기연하증이 66.5%(10/15, 6/9)이었고, 오심 61.5%(8/13), 식욕부진 53.8%(7/13), 복부동통 41.6%(5/12), 고창 37.5%(3/8)이었다. 각 환자별 종합적인 증상의 개선도는 현저한 개선이 2예(10%), 중등도 개선이 3예(15%), 약간개선이 11예(55%), 불변이 4예(20%)이었으며 종합적인 유효율은 80%(16/20)이었다. 부작용은 한 예에서도 관찰되지 않았다. 결론 : 본 제제는 기능성 소화불량증 환자의 증상개선에 추천할 만한 유효한 약제로 생각된다. Dyspepsia is a common symptom in gastroenterologic practice and trigger for numerous consultations with physician. The treatment of chronic functional dyspesia is unsatisfactory. This study was performed to evaluate the efficacy of the digestive compound (Winstal®) on 20 functional dyspepsia patients. On open trial, all patients were given 6 tablets daily for 2 weeks and we evaluated the efficacy of this preparation according to the degree of the improvement. The improvement of symptoms was 76.4%(13/17) in abdominal discomfort, 66.5%(10/15, 6/9) in abdominal distension and aerophagia, 61.5%(8/13) in nausea, 53.8%(7/13) in abdominal pain, and 37.5% (5/12) in flatulence, respectively. Overall effectiveness of subjective symptoms was 80% (16/20) and there were no untoward effects of the preparations during this study. As a result, We think that this preparation is an effective one to relieve symptoms of functional dyspepsia.
Isolation and characterization of a novel H9N2 influenza virus in Korean native chicken farm.
Lee, Yu-Na,Lee, Dong-Hun,Park, Jae-Keun,Lim, Tae-Hyun,Youn, Ha-Na,Yuk, Seong-Su,Lee, Youn-Jeong,Mo, In-phil,Sung, Haan-Woo,Lee, Joong-Bok,Park, Seung-Yong,Choi, In-Soo,Song, Chang-Seon American Association of Avian Pathologists [etc.] 2011 Avian diseases Vol.55 No.4
<P>An outbreak of avian influenza, caused by an H9N2 low-pathogenic avian influenza virus (AIV), occurred in a chicken farm and caused severe economic losses due to mortality and diarrhea. AIV was isolated and identified in a sample from an affected native Korean chicken. Genetic analysis of the isolate revealed a high sequence similarity to genes of novel reassortant H9N2 viruses isolated from slaughterhouses and live bird markets in Korea in 2008 and 2009. Animal challenge studies demonstrated that the replication kinetics and pathogenicity of the isolate were considerably altered due to adaptation in chickens. Vaccine protection studies indicated that commercial vaccine was not able to prevent virus shedding and clinical disease when chickens were challenged with the isolate. These results suggest that the novel H9N2 virus possesses the capacity to replicate efficiently in the respiratory system against vaccination and to cause severe disease in domestic chickens. The results also highlight the importance of appropriate updating of vaccine strains, based on continuous surveillance data, to prevent the possibility of a new H9N2 epidemic in Korea.</P>
Characterization of Reverse Leakage Current of Shallow Silicide Junction
Lee,Hi Deok,Lee,Sang Gi,Kim,Ha Joong,Lee,Young Jong,Hwang,Jeong Mo 대한전자공학회 1997 ICVC : International Conference on VLSI and CAD Vol.5 No.1
The properties of PECVD-WN_x films produced in a WF_6-N₂-H₂ gas system and their application as a glue layer for a W metallization were investigated. As the N₂/H₂ ratio in reactant gas increased from 0 to 1.5, the nitrogen concentration and the electrical resistivity in WNX film increased from 0 to 25 at % and 25.5 to 1009 Ω-cm, respectively. In the N₂/H₂ ranges, the microstructure of the film was also shown to be changed as bcc-W, mixture of W+WN+W₂N, amorphous or nanocrystal, and W₂N, in turn. The film of the best qualities was obtained at the N₂/H₂ ratio of 0.25, where it represented the most smooth surface, 230μΩ-cm of resistivity, 13 at.% of nitrogen concentration, nanocrystalline structure close to amorphous at as-deposited state, and 90% of bottom step coverage. In order to proceed further CVD-W metallization, a PECVD-W layer was employed as a seed layer for the stable deposition of the thermal CVD-W onto the WNX layer. A tri-layer structure of (thermal)CVD-W/PECVDW/PECVD-WN_x with a good thermal stability was successfully achieved in an in-situ process, and hence its application to CVD-W metallizations seemed to be promising.
Percutaneous Sacroplasty : Effectiveness and Long-Term Outcome Predictors
Lee, Jaehyung,Lee, Eugene,Lee, Joon Woo,Kang, Yusuhn,Ahn, Joong Mo,Kang, Heung Sik The Korean Neurosurgical Society 2020 Journal of Korean neurosurgical society Vol.63 No.6
Objective : To evaluate the effectiveness and long-term outcome predictors of percutaneous sacroplasty (PSP). Methods : This single-center study assessed 40 patients with sacral insufficiency fractures using the short-axis technique under C-arm flat-panel detector computed tomography (CT). Two radiologists reviewed the patients' magnetic resonance and CT images to obtain imaging findings before PSP and determine technical success, respectively. The short-term outcomes were visual analog scale score changes and opioid usage reductions. Long-term outcomes were determined using telephone interviews and the North American Spine Society (NASS) patient-satisfaction index at least one year after PSP. Results : Technical success was achieved without any significant complications in 39 patients (97.5%). Telephone interviews were possible with 12 patients and failed in 10 patients; death was confirmed in 18 patients. Fifteen patients (50%) re-visited the hospital and received conservative treatment, including spinal injections. Nine patients reported positive satisfaction (NASS patient-satisfaction index 1 or 2), while the negative satisfaction group (NASS patient-satisfaction index 3 or 4, n=3) showed a higher incidence of compression fractures at the thoracolumbar spine level (66.7% vs. 22.2%) and previous spinal injection history (66.7% vs. 33.3%). The poor response group also showed higher incidences of facet joint arthrosis (100% vs. 55.6%), central canal stenosis (100% vs. 22.2%), neural foraminal stenosis (33.3% vs. 22.2%), scoliosis (100% vs. 33.3%), and sagittal malalignment (100% vs. 44.4%). Conclusion : PSP was effective for sacral insufficiency fractures and showed good long-term outcomes. Combined compression fractures in the thoracolumbar spine and degenerative lumbar pathologies could be possible poor outcome predictors.