Quantitative Evaluation of Liver Function with MRI Using Gd-EOB-DTPA

Hun-Kyu Ryeom,Seong-Hun Kim,Jong-Yeol Kim,Hye-Jeong Kim,Jong-Min Lee,Yong-Min Chang,Yong-Sun Kim,Duk-Sik Kang 대한영상의학회 2004 Korean Journal of Radiology Vol.5 No.4

비신생물성 질환에 대한 췌십이지장 절제술의 안정성 및 수술 후 삶의 질에 대한 평가

은영아(Young A Eun),김상걸(Sang Geol Kim),윤혁진(Hyuk Jin Yun),김종렬(Jong Yeol Kim),김갑철(Gab Chul Kim),염현규(Hyun Kyu Ryeom),김성희(Sung Hi Kim),황윤진(Yun Jin Hwang),윤영국(Young Kook Yun) 대한외과학회 2007 Annals of Surgical Treatment and Research(ASRT) Vol.73 No.1

Purpose: Pancreaticoduodenectomy for mass-like lesions that are suspicious of malignancy sometimes reveals only nonneoplastic disease, especially in those cases where adequate tissues for biopsy are unavailable. In this study, we evaluated the outcomes and quality of life (QOL) after pancreaticoduodenectomy for treating nonneoplastic disease. Methods: The clinical data of 28 patients who underwent pancreaticoduodenectomy for nonneoplatic disease and trauma from Jan. 1992 to Feb. 2006 were reviewed retrospectively. The QOL was evaluated using the FACT-Hep questionnaire. The patients who underwent laparoscopic cholecystectomy for benign gallbladder disease were utilized as the control group. Results: 13.8% (28/203) of all the pancreaticoduodenectomized patients had nonneoplatic disease and trauma. Male patients were predominant (25/28) and all the trauma patients were male. The mean age was 48 (23∼72) years old. The indications for surgery included lesions suspicious for malignancy (16 cases), pancreaticoduodenal artery aneurysm (1 case), and pancreatoduodenal injury (11 cases). The histologic findings of the nonneoplastic lesions revealed benign inflammation of the bile duct (6 cases), chronic pancreatitis (8 cases), pancreatic pseudocyst (1 case), and fibrosis of the Ampulla of Vater (1 case). No surgical mortality occurred. However, the trauma patients group had higher morbidity (72.7% Vs 23.5%, respectively, P=0.01) and a longer hospital stay (68.0 days Vs 32.6 days, respectively, P=0.02) after surgery compared to the nonneoplastic disease patient group. The QOL of the patient who underwent pancreaticoduodenectomy for nonneoplatic disease was not different from that of the control group. Conclusion: Since pancreaticoduodenectomy for nonneoplastic disease was safe and the QOL of the patients was acceptable, it should be performed more often when malignancies can not be excluded from the differential diagnosis.

자돈 설사유발 대장균에 대한 키토산 올리고당의 항균효과

김희경,김희선,강문일,고홍범,김종렴,이응호 한국키틴키토산학회 1997 한국키틴키토산학회지 Vol.2 No.1

Recently chitosan has been focusing on the role of a potential and natural resource with antibacterial or antifungal effect. The purpose of the study was to confirm antibacterial effect of chitosan-oligosaccharides(OCHT)which was characterized by 96% deacethylation, mean molecular weight of 1,814 and mainly 7~ 14oligosacchardes, against 25 E. coli strains isolated from the feces of piglets with diarrhea. Serogroups of E. coli used included 088:K-, 0147:K88ac, 09:K103, 015:K-, 04:Kl2, 0157:K88ac, 015:K-, 09::K103, 020:K101, 01:K- and 0149:K91, E. coli isolates were cultured and adjusted at 2×107 CFU/ml in nutrient broth before adding OCHT diluted at 0.1, 0.01, 0.001, 0.0001, and 0.00002%, respectively. Until 12 hours after the addition and incubation(37℃) of each diluted OCHT in the E. coli-incubating flask, the optical density under 660nm wavelength was examined by one hour interval and showed significant difference(P<0.001) in antibacterial reaction to E.coli between the treatment of 0.0001 ~O.1% OCHT and the control during the test. From approximately 10 minutes to 12 hours after the treatment of 0.0001 ~O.5% OCHT to E. coli (2x107 CFU/ml) incubating in phosphate buffered saline(pH 6.0, 37℃), there was appeared significant decrease(P<0.001) of the number of E. coli colonies compared with the control. Also no E. coli colonies could find in the medium about 12 hours after the addition of 0.0001 ~O.5% OCHT. Consequently, we confirmed that OCHT used has a strong antibacterial effect to E. coli isolates causing diarrhea of piglets.

복수를 동반한 간경변증에서 뇌혈류저항의 증가

김성국,김종렬,최용환,정준모,전성우,권영오,이응주,탁원영,염현규 대한간학회 1999 Clinical and Molecular Hepatology(대한간학회지) Vol.5 No.1

Background/Aims : Portal hypertension in cirrhosis is associated with a hyperdynamic circulation, which is characterized by hypervolemia, high cardiac output, arterial hypotension and low peripheral vascular resistance. These circulatory abnormalities are thought to be secondary to a splanchnic arteriolar vasodilation related to the increase in portal pressure. Studies assessing regional hemodynamics in patients of cirrhosis with ascites have shown vasoconstriction in the renal circulation and in peripheral vascular territory. This study was designed to assess the cerebral vascular resistance in cirrhotic patients with ascites. Methods : The resistive index in the middle cerebral artery and in a renal interlobar artery were measured by Doppler ultrasonography in 12 cirrhotic subjects without ascites, 23 cirrhotic subjects with ascites, and 8 healthy subjects. The arterial blood pressure and plasma renin and norepinephrine concentration, which reflect the activity of the renin-angiotensin and sympathetic nervous systems respectively, were also measured. Results : The resistive index in the middle cerebral artery were significantly higher in cirrhotic patients with ascites (0.58±0.04, mean standard deviation) than in cirrhotic patients without ascites (0.53±0.02, P$lt;0.01) and in control subjects (0.50±0.05, P$lt;0.01). The resistive index in the middle cerebral artery showed direct correlation with renal resistive index (r = 0.52, P$lt;0.01), plasma renin activity (r = 0.44, P$lt;0.01) and norepinephrine (r = 0.33, P$lt;0.05). The resistive index in the middle cerebral artery showed an inverse correlation with mean arterial pressure (r = -0.59, P$lt;0.01). Conclusion : The results suggest that in patients of cirrhosis with ascites, independent of the amount of ascites, there is a cerebral vasoconstriction which is related with the arterial hypotension and the overactivity of vasoconstrictor systems. (Korean J Hepatol 1999;5:33-42)

Controller Design of a Novel Power Conditioning System with an Energy Storage Device for Renewable Energy Sources under Grid-Connected Operation

Park, Sun-Jae,Lee, Hwa-Seok,Kim, Chan-In,Park, Joung-Hu,Jeon, Hee-Jong,Ryeom, Jeongduk The Korean Institute of Power Electronics 2013 JOURNAL OF POWER ELECTRONICS Vol.13 No.3

As a result of the depletion of fossil fuels and environmental contamination, it has become important to use renewable energy. For the stable utilization of renewable energy sources, energy storage devices must be used. In addition, renewable and distributed power sources with energy storage devices must operate stably under grid-connected mode. This paper proposed dynamic response modeling for renewable power generation systems including a charger/discharger with an energy storage device in order to derive a method to guarantee stable operation while fully utilizing the energy from the energy storage device. In this paper, the principle operation and design guidelines of the proposed scheme are presented, along with a performance analysis and simulation results using MATLAB and PSIM. Finally, a hardware prototype of a 1kW power conditioning system with an energy storage device has been implemented for experimental verification of the proposed converter system.

복강 내 결핵성 농양의 CT 소견과 임상경과

하창윤 ( Chang Yoon Ha ),김종열 ( Jong Yeol Kim ),김갑철 ( Gab Chul Kim ),염헌규 ( Hun Kyu Ryeom ),김혜정 ( Hye Jung Kim ),이희중 ( Hui Joong Lee ),강덕식 ( Duk Sik Kang ) 대한내과학회 2008 대한내과학회지 Vol.74 No.3

목적: 복강 내 결핵성 농양은 매우 드물지만 다양한 양상으로 발병하기 때문에 암성 복막염과의 감별이 쉽지 않다. 이 연구에서는 복강 내 결핵성 농양의 CT 소견과 임상경과에 대하여 후향적으로 분석해 보고자 하였다. 방법: 수술 혹은 조직 생검을 통해 병리학적으로 복강 내 결핵성 농양으로 확진되고 CT를 시행한 11명의 환자(남자 3명, 여자 8명, 평균 34.8세, 21~66세)를 대상으로 하였으며, 25 CT와 의무기록을 후향적으로 분석하였다. 평균 추적기간은 15개월(12~32개월)이었다. 결과: 11명의 환자에서 16개의 농양이 발견되었고, 이들 중 4개(25%)의 농양은 우측 간주위 공간, 4개(25%)는 좌측 간주위 공간, 3개(19%)는 비장주위 공간, 2개(13%)는 좌측 횡경막하 공간에 있었으며 우측 횡경막하 공간과 우하복부공간, 좌하복부 공간에 각각 1개씩 있었다. 농양의 크기는 1~8 cm(평균, 4 cm)이었으며, 농양의 모양은 12개가 난원형이었고, 4개는 구형이었다. 농양벽의 두께는 1~5 mm(평균, 3 mm)이었다. 16개의 농양 모두에서 농양벽이 얇고, 조영증강되었으며 농양벽 석회화는 보이지 않았으며 12개에서 내부의 격벽이 보였다. 림프절 종대가 2명, 복막의 비후와 대망 혼탁의 소견이 3명에서 있었으며 액체 저류의 소견은 모두 없었다. 복막의 조영증강 소견은 6개의 농양에서 보였다. 동반된 다른 장기의 결핵 이환은 4명에서 발견되었는데, 결핵성 흉막염 2명, 폐결핵과 장염 1명, 폐결핵과 경부 림프절 결핵 1명이었다. 11명 중 5명은 결핵의 병력이 없었으며 농양이 결핵의 일차 병변이었으며 6명은 결핵성 복막염으로 치료 중인 환자로 농양이 역설반응으로 생긴 새로운 병변이었다. 역설반응으로 진단된 6명의 농양 발현 시기는 치료 후 66~116일(평균, 88일)이었다. 모든 환자는 6~12개월동안 항결핵제 치료를 하였으며, 5명은 수술을 하였고, 모두 완치되었다. 추적기간은 12~32개월(평균, 15개월)이었다. 결론: 복강 내 결핵성 농양은 복부 결핵의 일차 병변 또는 결핵성 복막염의 역설반응으로 생길 수 있으며, 상복부 공간에 위치하는 다양한 크기의 조영증강되는 얇은 벽을 가진 낭성 병변의 소견을 보인다. Background/Aims: Intraperitoneal tuberculous abscesses develop infrequently. Because of overlapping features it is difficult to differentiate a tuberculous abscess from carcinomatosis peritonei. The aim of this study was to define the computed tomography (CT) findings and clinical course of the intraperitoneal tuberculous abscess. Methods: The study included 11 patients (3 males, 8 females, mean age 34.8 years) with a pathologically proven intraperitoneal tuberculous abscess. We analyzed the CT findings and reviewed the medical records retrospectively. Results: Sixteen abscesses were found in 11 patients. The locations of the abscesses were in the right subphrenic space (n=1), right perihepatic space (n=4), left perihepatic space (n=4), left subphrenic space (n=2), perisplenic space (n=3), right lower abdominal space (n=1), and left lower abdominal space (n=1). Five patients were proven to have abdominal tuberculosis while six patients had paradoxical responses to antituberculosis therapy for tuberculous peritonitis. The abscess lesions presented on the CT scan as thin walled cystic enhancing lesions without calcification (n=16), a septated mass (n=12), with enlargement of lymph nodes (n=2), and peritoneal and omental haziness (n=3). The mean duration from commencement of treatment to onset of a paradoxical response was 88 days. All patients had antituberculosis therapy for 6 to 12 months and five patients underwent surgery. The mean follow-up was 15 months. Conclusions: The intraperitoneal tuberculous abscess appeared as an ovoid cystic lesion with a slightly enhanced thin wall in the upper abdomen, in the perihepatic space on the CT scan; such as lesion can be the primary lesion of abdominal tuberculosis or associated with the paradoxical response of tuberculous peritonitis. (Korean J Med 74:243-249, 2008)

Controller Design of a Novel Power Conditioning System with an Energy Storage Device for Renewable Energy Sources under Grid-Connected Operation

Sun-Jae Park,Hwa-Seok Lee,Chan-In Kim,Joung-Hu Park,Hee-Jong Jeon,Jeongduk Ryeom 전력전자학회 2013 JOURNAL OF POWER ELECTRONICS Vol.13 No.3

As a result of the depletion of fossil fuels and environmental contamination, it has become important to use renewable energy. For the stable utilization of renewable energy sources, energy storage devices must be used. In addition, renewable and distributed power sources with energy storage devices must operate stably under grid-connected mode. This paper proposed dynamic response modeling for renewable power generation systems including a charger/discharger with an energy storage device in order to derive a method to guarantee stable operation while fully utilizing the energy from the energy storage device. In this paper, the principle operation and design guidelines of the proposed scheme are presented, along with a performance analysis and simulation results using MATLAB and PSIM. Finally, a hardware prototype of a 1kW power conditioning system with an energy storage device has been implemented for experimental verification of the proposed converter system.

Antibacterial Effect for Staphylococcus aureus and Production for Cytokines of Chitosan Oligosaccharides in ICR Mice

(Jin San Moon),(Yi Seok Joo),(Hee Kyung Kim),(Mun Il Kang),(Jong Ryeom Kim),(Young Sun Yun),(Young Nam Lee) 한국수의공중보건학회 2000 한국수의공중보건학회 추계학술대회 Vol.- No.-