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PVA-ECC를 활용한 Half PC 복합체의 역학적 특성에 관한 실험적 연구
김재환,김영덕,김갑수,조봉석,장종호,김무한 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2
ECC represents one particular class of HPFRCC, which are defined by an ultimate strength higher than their first cracking strength and the formation of multiple cracking during the inelastic deformation process. This study is to provide the fundamental data for the development of hybrid construction method such as the half PC(Precast concrete) reinforced by PVA-ECC, the mechanical properties of half PC according to the alteration of properties of PVA-ECC in terms of the type of fiber, Vr, S/M, placing height of PVA-ECC, are experimentally investigated. As the results. it is found that the half PCs of PVA-ECC have very higher mechanical performance in terms of yield load, strain capacity beyond yield point and maximum flexural load than that of mortar. Also, flexural crack in the half PCs of PVA-ECC are not localized at first crack and are growed to many micro crack, especially multiple cracking in specimen of P(12)-30-0.1ㆍ3 occurred.
중증 허혈성 지체질환 환자에서 시행된 vascular endothelial growth factor의 혈관신생 유전자치료 1예
김현중,장신이,김종묵,김선영,김병문,김원배,김덕경 대한내과학회 2003 대한내과학회지 Vol.64 No.1
저자 등은 기존의 치료에 반응하지 않은 중증 허혈성 지체질환 환자를 대상으로 하여 vascular endothelial growth factor를 이용한 혈관신생 유전자 치료를 시행하였다. 치료 후 환자의 허혈에 의한 하지 통증이 현격하게 감소하고 상처의 진행이 측부혈관이 많이 증가됨이 관찰되어 이에 문헌고찰과 함께 보고하는 바이다. We report VEGF-induced angiogenic gene therapy in a patient with critical limb ischemia, who did not respond to conventional treatment. This patient was the first case in a dose-escalating series of phase I clinical trial. The patient had severe resting pain, gangrene and diffuse ulcer in his left foot. Total 1,000㎍ of naked DNA encoding human VEGF165 was administered intramuscularly to 8 sites of the loft lower extremity. Four weeks after the first 1,000㎛ was administered to the same sites (total dose: 2,000㎛). After gene therapy, resting pain gradually reduced and the amount of analgesics taken by the patient decreased. The ischemic wound of lower extremity slightly improved. However, there was no complete wound healing at 12 weeks of treatment. Digital subtraction angiography at 12 weeks after gene therapy showed an increase in collateral vessels at the mid-tibial, ankle and foot arch levels. Immediately and up to 12 weeks, there was no complication related to gene therapy. These findings may be cautiously interpreted to indicate that intramuscular injection of naked plasmid DNA of VEGF_165 may induce therapeutic angiogencsis in a patient with critical limb ischemia. Further clinical evaluation of VEGF-induced gene therapy is needed to evaluate the safety and efficiency of this treatment.(Korean J Med 64:85-90, 2003)
내구성을 고려한 표면피복재의 성능평가에 관한 실험적 연구
김영덕,조봉석,윤종기,김용로,장종호,김무한 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2
It is recognized that reinforcement corrosion is the main distress behind the present concern regarding concrete durability. The basic method to prevent reinforcement corrosion is coating the reinforcement concrete with surface coating materials but evaluating their performance is necessary to the work satisfactory because they have different performance for each other. In this study. to evaluate performance of surface coating materials, we compare their properties in terms of sticking strength and permeability of carbonation, chloride ion and water with actual reinforcement corrosion under environment of complex deterioration. The results showed that an increase in age also decreases Carbonation velocity coefficients, increases Chloride ion diffusion coefficients and increases water absorption coefficients. As well, an increase in age also increases corrosion of reinforcement due to permeability of carbonation and chloride ion. And sticking strength of inorganic coating material is higher than organic coating material.
Sdoium Borohydride에 의한 Aldehydes, Ketones 및 Acid Chlorides의 환원반응
김종호,정덕상 慶熙大學校 1980 論文集 Vol.10 No.-
Sodium borohydride, in water or methanol solution, is an effective reagent for the conversion of aldehydes and ketones to the corresponding alcohols. Its properties are compared with those of litium aluminum hydride and it is shown to be superior in selective reductions. Acid chlorides are reduced to primary alcohols in non-aqueous media, but carboxylic acids, anhydrides, esters and nitriles are practically unaffected.
김종덕 정보과학연구소부산외국어대학교 2002 情報科學論集 Vol.4 No.-
Spectral decomposition and singular value decomposition which are commonly used matrix decomposition methods in the principal components regression are explained. Computational implementation of principal components regression procedure and applicable equations are suggested and the equivalence of the formulas are shown. Data scaling is explained, and the effect of the unit-norm standardization and correlation transformation are compared in the principal components regression procedure. The results of the two standardization methods are often confused in the literature and it is hoped that this paper will clarify the difference.
X' X + C가 비정칙일 때의 일반화능형회귀의 일반적 해의 유도와 해석
김종덕 부산 외국어 대학교 2004 外大論叢 Vol.28 No.-
Generalized ridge regression in which X is of size n×m with rank γ (≤(n, m)) is considered. A detailed derivation process for the estimated regression coefficients and response vectors is shown when the original X (or standardized X) is used instead of the orthogonally transformed one in the situation of possibly singular X'X + C. The regression vector is expressed in such a way that the transformed C is revealed