SOL-GEL법을 이용한 Ta₂O_(5) 감지 게이트 pH-ISFET의 제조와 그 동작특성

장기석,이정철,조병욱,권대혁,김창수,손병기 경북대학교 센서기술연구소 1995 센서技術學術大會論文集 Vol.6 No.1

Low drift pH-ISFET is presented in this paper. Ta_(2)O_(5), known as a good pH sensing membrane, was formed by sol-gel method on Si_(3)N_(4)/SiO_(2) gate of pH-ISFET. It has been reported that the drift of the pH-ISFET is caused by the surface deterioration or hydration of sensing membrane. Hydration is resulted from diffusion of ions into the sensing membrane. It is reported that Ta205 film does not show surface deterioration but hydration while Si_(3)N_(4) film is not hydrated but its surface is deteriorated. Therefore, ultra thin(about 100Å) Ta_(2)O_(5) sensing membrane was formed by sol-gel method on the Si3N4to shorten the hydration time. The fabricated Ta205 pH-ISFET showed good sensitivity(58~59 mV/pH) in a wide pH range(pH3~11) as well as very low drift (0.06 pH/day)

한국에서의 Human T-Cell Leukemia Virus Type-1(HTLV-1)에 대한 혈청학적 및 역학에 관한 연구

이영열,이성열,김은실,이홍복,김병국,이문호,박선양,김노경,서철원,규경채,최강원,조한익,고월청,야마구찌이찌세이 대한내과학회 1986 대한내과학회지 Vol.31 No.2

Type-C retrovirus, human T-cell leukemia virus type-l(HTLV-1), has been shown to be associated etiologically with adult T-cell leukemia, which is an endemic disease in southwestern parts of Japan. We examined the seroepidemiological characteristics of antibody to adult T-cell leukemia virus associated antigen (anti-ATLA-antibody) by the indirect immunofluorescent assay and ELISA from the healthy individuals and various diseased patients in the Republic of Korea, a country adjacent to Japan in which HTLV-1 is endemic. The results were as follows. 24 out of 9,603 individuals(0.25%) were seropiositive. The positve rate was 0.17% in males and 0.36% in females, the sex difference was female predominent relatively. HTLV-1 carriers were found 16 individuals in Seoul, 5 in Kyonggi area, 1 in Chungnam and Jonbuk, respectively, but found only 1 individual in Busan city and Jaejoo area close to southwestern parts of Japan. Positive rate to anti-ATLA-antibody seemed to be high in older age, especially at the 50s(0. 4Yo). In conclusion the prevalence rate of anti-ATLA- antibody seemed to be very low in the Republic of Korea adjacent to Japan in which HTLV-1 is endemic and no patient with adult T-cell leukemia has been found as yet. Also we noted that the Republic of Korea is not an endemic area to HTLV-1.

급성 골수성 백혈병(M6)에 합병된 중추성 요붕증 1 예

김성연,조보연,이홍규,고창순,민헌기,김병국,김노경,신찬수,이명식,강덕현,조종태 대한내과학회 1989 대한내과학회지 Vol.37 No.2

Leukemia is known to be an extremely rare cause of diabetes insipidus. We report a case of diabetes insipidus as a complication of leukemia. An 18 year-old man was admitted because of polyuria polydipsia and fever. Bone marrow aspiration and biopsy revealed the diagnosis of acute erythroleukemia (AML, M6). On the water deprivation test, the diabetes insipidus was confirmed to be of the central type. He was managed with intranasal vasopressin for diabetes insipidus with good response. Induction chemotherapy was administered without response, and the patient died of septicemia and respiratory failure 2 months after initial diagnosis. A short review of the literature related to this subject is also presented.

사료내 해조분의 사용이 비육돈의 성장 및 도체성상에 미치는 영향

한인규,양창범,조원탁,정원덕,배극환 한국영양사료학회 1999 韓國營養飼料學會誌 Vol.23 No.3

본 연구는 해조분 (감태, 학명 Lamianriales과 Ecklonia Cava Kjellman)의 첨가 수준에 따른 비육돈의 성장 및 도제 특성에 미치는 영향을 조사하기 위하여 평균 체중 53.7 ㎏인 삼원 교잡종(Yorkshire × Large White × Duroc) 비육돈 총 150 마리를 5처리, 6반복, 반복당 5두씩 공시하였다. 처리구는 대조구, 항생제 첨가구, 해조분 1% 첨가구 (KM-1%), 해조분 2% 첨가구 (KM-2%), 해조분 3% 첨가구 (KM-3%)등 5처리구를 두었다. 사양 성적에 있어서 해조분 첨가구와 대조구 사이에 통계적 유의차는 없었으나 비육 후기 기간 중 해조분 첨가구의 일당증체량이 대조구나 항생제 처리구에 비해 유의하게 낮았다 (P<0.05). 영양소 소화율 및 배설량에서는 해조분 3% 첨가시 조단백질, 조지방 및 칼슘의 소화율이 현저하게 저하되었으나 건물 소화율은 각 처리구 간에 통계적 유의차는 없었다. 또한 해조분 3% 첨가구의 건물 및 질소 배설량이 대조군에 비해 통계적으로 유의하게 높았으나 인 배설량은 오히려 해조분 첨가구가 유의하게 낮았다. 도체 성적은 해조분의 첨가로 인한 각 처리구간의 유의차는 없으나 해조분 첨가구가 대조군에 비해 등지방 두께가 증가하는 경향을 나타냈다. 해조분의 수준이 2% 이상되는 수준에서는 등심의 무게가 증가하는 경향을 나타냈으며, A, B 등급 출현율은 해조분 2% 첨가구에서 가장 우수한 성적을 나타냈다. 해조분 첨가수준에 따라 사료비가 감소하는 결과를 얻었으나 통계적인 유의차는 없었으며, 대조구에 비해 해조분 첨가수준에 따라 비육돈 두당 상대적인 이윤은 각각 102, 102 그리고 101%로 증가하였다. 이러한 경향은 해조분 첨가구에서 A 및 B 등급의 출현율이 더 높게 나타난 결과에 기인하는 것으로 사려된다. This study was conducted to evaluate the nutritional values of kelp meal (Ecklonia Cava Kjellman, Lamianriales) on the growth performance, carcass characteristics of finishing pigs. A total of 150 three crossbred (Yorkshire × Landrace × Duroc) finishing pigs (initially weighing 53.7 ㎏ body weight) were allotted into 5 treatments with 6 replications, 5 heads per pen in a completely randomized block design. Dietary treatments included 1) Control, 2) Antibiotics (chlortetracycline 0.05%; CTC), 3) Kelp meal 1% (KM-1%), 4) Kelp meal 2% (KM-2%), 5) Kelp meal 3% (KM-3%). During the earlier finishing period (54∼90 ㎏), there were no significant differences in growth performances among treatments. However, average daily gain of pigs fed kelp meal were significantly lower (P<0.05) than control and CTC group during the late finishing period (90∼107 ㎏). Digestibilities of crude protein, crude fat and calcium were markedly decreased and excretion of DM and N were increased during phase I (54∼90 ㎏) when kelp meal was included at the level of 3% in the diet, although the dry matter digestibility was not significantly different. Phosphorus excretion was significantly low in pigs fed kelp meal diet than control and CTC goup pigs. Kelp meal did not affect the carcass characteristics of finishing pigs. Backfat thickness had a tendency to increase with the supplementation of kelp meal in the diet. Loin eye weights of pigs fed more than 2% of kelp meal diets were higher than other groups. The appearance of A and B grade in carcass evaluation was highest in pigs fed 2% kelp meal diet among all treatments. Consequently, it is suggested that kelp meal could be included at the level of 2% in the finisher diet. Though, there was no significant difference among treatments, feed cost was shown to be decreased by the use of kelp meal comparing control diet. An increase of relative margin per pig was obtained by the use of kelp meal compared to the pigs fed control diet. This trends were resulted from the higher carcass prices by the more A and B grade appearances in pigs fed kelp meal diets. Despite the low feed intake, improved feed efficiency slightly affected feed cost per weight gain and reflected on production cost.

활어의 저온 . 고밀도 저장중의 혈액성분 및 근육성분의 변화

조영제,김종보,허병기 한국산업식품공학회 1998 산업 식품공학 Vol.2 No.2

To achieve the low temperature-high density transportation conditions of live fish, the optimal low temperature of live plaice, Paralichrhys olivaceus was investigated by the change of dissolved oxygen in the sea water and the survival times during storage at various temperatures. The changes of serum components (LDH and GPT), muscle components (lactate and ATP and to related compounds) and breaking strength in the muscle(were also studied during storage at the conditions of stress (5℃-10% and 50% density and recovery (18℃-5% density). The optimal temperature for the low temperature-high density transportation of live plaice was found to be 5℃. Serum components of live plaice gradually increased during storage under the condition of low temperature-high density, and these values then decreased to the initial levels after 6-1 0 hrs of storage time recovery condition. The level of lactate in the muscle gradually increased in stress conditions, and then these values also decreased in recovery condition. The ratios of ATP to ATP and its related compounds {ATP/(ATP+ADP+ AMP+IMP)}×100 in the muscle showed 42% after 18hrs storage in stress condition (5℃-50%). Otherwise, the ratios returned to their original levels within 6 hrs of storage time in recovery conditions. The level of breaking strength in the muscle was higher than initial levels up to 12 hrs storage, but these values were decreased to the original levels after 18 hrs storage time in stress conditions(5℃-50%).

무가압 침투법에 의해 제조된 Al/BN 복합재료의 미세조직과 인장성질

조수연,이건배,심호섭,허성우,유황룡,권훈 대한금속재료학회(대한금속학회) 2000 대한금속·재료학회지 Vol.38 No.12

Spontaneous infiltration and strengthening behaviors were analyzed in terms of microstructures and tensile properties of Al/BN composite fabricated by pressureless infiltration technique, compared with control alloy without BN fabricated by the same method. The Mg₃N₂ formed by the reaction of Mg vapor and nitrogen gas, which coated the particles in the powder bed, is believed to induce spontaneous infiltration through a great enhancement of wetting via the following reaction, Mg₃N₂+ 2Al→2AlN + 3Mg. This was identified by the finding of AlN particle layers on the surfaces of old Al particles in the powder bed, which contacted with the infiltrating melt. In addition, unreacted Mg₃N₂ was observed outside the composite, where the Al melt directly did not come into contact. Fine AlN particles formed in-situ resulted in a significant strengthening even in the control alloy with no addition of BN. In the composite reinforced with BN, additional AlN was formed by the interfacial reaction of the BN and Al melt as well as AlN by the in-situ reaction. Consequently, both the BN particles and the additional AlN particles formed by the interfacial reaction led to a further strengthening in the composite, as compared to control alloy strengthened by the AlN particles formed in-situ.

차동 플로팅매스형 전자 트랜스듀서를 이용한 이식형 인공중이의 실험적 평가

송병섭,김명남,조진호,정주영,김동만,이건일 경북대학교 전자기술연구소 2001 電子技術硏究誌 Vol.22 No.2

Recently, implantable middle ear hearing system have attracted hearing impaired person's attention because it can overcome the disadvantages of conventional hearing aids such as sound distortion, sound feedback and howling effect. In this study, implantable middle ear hearing system, using DFMT(differential floating mass type) transducer that has two magnets glued with the same pole facing was evaluated by performing several experiments. The results of vibration experiments using DFMT transducer showed several advantages such as high vibration efficiency, good frequency response, minimal influencing by external magnetic flux, etc. And the results of the ABR(auditory brainstem response) test using guinea pig proved the performance of transducer in the animal's body and the possibility of clinical application of the implantable middle ear system for mild to severe hearing loss patients.

한국산 날치과(Beloniformes , Exocoetidae)어류 5 종의 분류학적 재검토

김종만,김진구,유정화,조선형,명정구,강충배,김용억 한국어류학회 2001 韓國魚類學會誌 Vol.13 No.2

Taxonomic review of the five flyingfishes, Parexocoetus mento (Valenciennes), Cheilopogon agoo (Temminck et Schlegel), Cheilopogon heterurus doederleini (Steindachner), Cheilopogon cyanopterus (Valenciennes), Hirundichthys oxycephalus (Bleeker) were carried out based on samples collected from the South sea and around sea of Jeju Island of Korea from 1996 to 1998. Parexocoetus mento (Valenciennes) and Cheilopogon cyanopterus (Valenciennes) were revealed as the unrecorded species in Korea, which were named as "Men-to-hwang-nal-chi" and "Ki-geom-nal-chi" respectively. Parexocoetus mento is differed from P. barchypterus in having no chin barbels in juveniles, and Cheilopogon cyanopterus is distinguished from C. agoo in the branched form of pectoral fin rays and from C. heterurus doederleini in the numbers of the dorsal fin ray and the color of pectoral fins.

중탄소 Boron 강의 가스침질탄화처리에 의해 형성된 화합물층의 마모특성에 관한 연구

이상윤,이해우,조효석,이준범,박기원,오도원 한국열처리공학회 1999 熱處理工學會誌 Vol.12 No.2

The study on the wear characteristics of compound layers formed during gaseous nitrocarburising in the medium carbon boron steels and the plain carbon steel has been carried out by using a pin-on-disc type wear test machine under the oil lubricating condition at room temperature and by varying applied loads, sliding speeds and wear distances. Values of friction coefficient measured at the sliding speed of 0.4m/sec under the oil lubricating condition have been shown to decrease considerably with increasing applied load and become gradually a constant value as load is increased to a higher value, showing that the transition load for friction coefficient appears at an applied load of 247.2N. The length and volume wear rates of compound layer have been revealed to relatively constantly increase, also showing that the wear life per unit thickness of compound layer turns out to be superior as porous layer has a denser and thinner appearance. As the sliding speed increases during wear test performed by varying sliding speed at a load of 63.2N under the oil lubricating condition for medium carbon boron steel nitrocarburised in gas atmosphere, the wear rate has been found to increase, the friction coefficient to decrease and the wear life per unit thickness of compound layer to decrease considerably.

사료내 Tryptophan , Isoleucine 및 Valine 의 수준이 14 일령 조기이유자돈의 성장에 미치는 영향

김지훈,한인규,조원탁,권찬호,강완병 한국영양사료학회 1999 韓國營養飼料學會誌 Vol.23 No.4

적 요 본 연구는 사료내 아미노산의 함량이 조기이유자돈의 성장에 미치는 영향을 조사하기 위해 총 432 두의 삼원교잡 조기이유자돈 (14±2 일령 ; Yorkshire×Landrace×Duroc)을 이용하여 사료내 tryptophan, isoleucine 및 valine의 수준에 따른 성장 (2 주간) 및 영양소 소화율을 각각 조사하였다. 사료내 아미노산의 수준은 관행사료에 합성 아미노산을 이용하여 달리 두었으며, 자돈은 15m×2.5m(가로×세로) 규격의 돈방에서 사육하였다. 실험 I에서는 사료내 tryptophan 함량에 따라 4처리(0.22%, 0.25%, 0.28% 및 0.31%)로 사양시험을 실시하였으며, 그 결과 사료내 tryptophan 함량이 0.25%인 처리구에서 사양기간동안 유의적으로 높은 일당증체 (ADG) 및 일당 사료섭취량 (ADFI)을 나타냈으며 (P<0.05), 사료요구율 (F/G)은 사료내 tryptophan 함량이 0.28%인 처리구에서 우수한 성적을 나타냈지만 유의차는 없었다. 일반성분 소화율은 전기 0~7일 동안 조희분을 제외한 일반성분들이 유의적인 차이를 보였고, 0.25% 이상의 tryptophan을 급여한 처리구들에서 높은 소화율을 보였다. 필수 아미노산의 소화율은 사료내 tryptophan 함량이 0.25% 이상인 처리구에서 높게 나타났다. 자돈의 사양성적 및 영양소 소화율에 따르면 사료내 tryptophan의 적정 수준은 0.25%이며, 이는 lysine 대비 15% 수준이 된다. 실험 II에서는 사료내 isoleucine 함량에 따라 4처리 (0.80%, 0.90%, 1.00% 및 1.10%)로 사양시험을 실시하였다. 사양시험 결과 사료내 isoleucine 함량이 1.00%인 처리구에서 ADG와 ADFI가 높은 성적을 나타냈으나 처리구간의 유의적인 차이는 나타나지 않았다. F/G에서도 유의차는 없었으나 0.90% 수준의 처리구에서 우수한 것으로 조사되었다. 일반성분 소화율에 있어서는 처리 수준별로 유의적인 차이를 나타냈는데, isoleucine 함량이 1.10%이상인 처리구에서 유의적으로 우수한 성적을 나타냈다. 필수아미노산의 경우 isoleucine 함량이 1.00%와 1.10%인 처리구에서 유의적으로 높은 소화율을 나타냈다. 또한 일령이 증가함에 따라 아미노산의 소화율에 약간의 개선이 있는 것으로 나타났다. 이 실험에서 얻어진 isoleucine의 요구량은 1.00%인 것으로 생각되며, 이는 lysine에 대한 비율로 60.6%에 해당한다. 실험 III은 사료내 valine 함량을 4수준 (0.96%, 1.06%, 1.16% 및 1.26%)으로 처리구를 두었다. 사료내 valine 함량이 1.06% 이상인 처리구에서 유의적으로 우수한 사양성적을 나타냈고, valine 함량이 0.96%인 처리구에서 유의적으로 낮은 것으로 조사되었다. F/G은 1.16% 처리구에서 우수한 성적을 나타내었지만 유의차는 없었다. 단백질 소화율을 제외한 일반성분의 소화율이 사료내 valine 함량이 1.16%와 1.26%인 처리구에서 0~7일동안 유의적으로 우수한 것으로 나타났으며, 사료내 valine 함량이 0.96%인 처리구에서 소화율이 낮은 것으로 나타났다. 7~14일 동안에는 조지방 소화율에서 유의적인 차이를 보였다. 필수 아미노산의 소화율은 사료내 valine 함량이 1.06% 이상인 처리구에서 유의적인 개선효과를 나타냈다. (0~7 day). 본 실험에서 제시된 valine 요구량은 1.16%이었으며, 이를 lysine에 대한 비율로 나타내며 70.4%에 해당한다. 결론적으로 평균 14일령의 조기이유자돈 사료내 적정 아미노산의 함량은 tryptophan 0.25%, isoleucine 1.00%, valine 1.06%인 것으로 나타났다.