http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Diabetes Mellitus and Prostate Cancer Risk in Asian Countries: a Meta-analysis
Long, Xiang-Ju,Lin, Shan,Sun, Ya-Nan,Zheng, Zhen-Feng Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8
Background/Aims: Diabetes mellitus (DM) is widely considered to be associated with risk of cancer, but studies investigating the association between DM and prostate cancer in Asian countries have reported inconsistent findings. We examined this association by conducting a detailed meta-analysis of studies published on the subject. Methods: Cohort or case-control studies were identified by searching Pubmed, Embase and Wanfang databases through May 30, 2012. Pooled relative risk (RR) with its corresponding 95% confidence interval (95% CI) were calculated using the random-effects model. Subgroup analyses were performed by the study type. Results: Finally, we identified 7 studies (four cohort studies and three case-control studies) with a total of 1,751,274 subjects from Asians. DM was associated with an increased risk of prostate cancer in Asians (unadjusted RR= 2.82, 95% CI 1.73.4.58, P < 0.001; adjusted RR= 1.31, 95% CI 1.12.1.54, P = 0.001). Subgroup analyses by study design further confirmed an obvious association. Conclusion: Findings from this meta-analysis strongly support that diabetes is associated with an increased risk of prostate cancer in Asians.
Characterization and uncertainty of uplift load-displacement behaviour of belled piers
Lu, Xian-long,Qian, Zeng-zhen,Zheng, Wei-feng,Yang, Wen-zhi Techno-Press 2016 Geomechanics & engineering Vol.11 No.2
A total of 99 full-scale field load tests at 22 sites were compiled for this study to elucidate several issues related to the load-displacement behaviour of belled piers under axial uplift loading, including (1) interpretation criteria to define various elastic, inelastic, and "failure" states for each load test from the load-displacement curve; (2) generalized correlations among these states and determinations to the predicted ultimate uplift resistances; (3) uncertainty in the resistance model factor statistics required for reliability-based ultimate limit state (ULS) design; (4) uncertainty associated with the normalized load-displacement curves and the resulting model factor statistics required for reliability-based serviceability limit state (SLS) design; and (5) variations of the combined ULS and SLS model factor statistics for reliability-based limit state designs. The approaches discussed in this study are practical and grounded realistically on the load tests of belled piers with minimal assumptions. The results on the characterization and uncertainty of uplift load-displacement behaviour of belled piers could be served as to extend the early contributions for reliability-based ULS and SLS designs.
( Su Hyun Cho ),( Min Ju Choi ),( Zhen Long Zheng ),( Do Young Kim ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2
Background: Intralesional corticosteroid injection is a commonly used first line therapy for alopecia areata (AA). However, assessing the treatment response clinically can be troublesome and can vary between individuals. Objectives: To trace the changes in dermoscopic findings of active AA lesions after repeated intralesional corticosteroid injection treatment. Methods: Fifty six AA patients who initially showed a positive hair pull test were enrolled. Intralesional triamcinolone acetonide injection at a concentration of 5 mg/ml was done at a 3-6 weeks interval. Serial dermoscopic examinations at the preselected alopecic patches were performed initially and before every injection, which was continued until the disease activity turned negative. Results: Among the 56 AA patients, the mean age was 32.8±12.5 years, and the mean duration of AA lesions were 11.2±17.4 weeks. Initially, yellow dots were the predominant dermoscopic finding seen in 51 patients (91.1%), followed by black dots (64.3%). When the AA lesions clinically stabilized, short vellus hair was the predominant finding seen in 54 patients (96.4%), and black dots were still observed in 50% of patients. Conclusion: Although dermoscopic examination is frequently used in AA, studies about its use as an assessment tool of treatment response is rare. It can be used as an ancillary tool to estimate disease activity of AA, and also can be helpful in deciding when the intralesional corticosteroid injection should be discontinued.
P190 : Dermoscopic findings in radiation-induced alopecia after angioembolization
( Su Hyun Cho ),( Min Ju Choi ),( Zhen Long Zheng ),( Do Young Kim ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2
Background: Endovascular intervention is increasingly being used as the first choice of treatment for cerebral aneurysms or vascular lesions of the brain. Although cases of temporary alopecia after endovascular brain surgery have occasionally been reported, dermoscopic findings of these lesions have rarely been discussed. Objectives: To evaluate the dermoscopic findings of alopecia lesions which developed after radiation exposure during angioembolization. Methods: Seven patients presenting with an alopecic patch after angioembolization were enrolled in this study. Dermoscopic examination was performed to observe the characteristics of radiation-induced alopecia after an endovascular interventional procedure. Results: Among the 7 patients, the mean age was 54.1±14.1 years and the mean duration of alopecia lesions were 6.9±9.3 weeks. Most alopecic lesions showed a rectangular shape, presenting both at the occiput and temple area which may be related to the 3-dementional exposure of radiation, and the position of patient during procedure. Yellow dots were the predominant dermoscopic finding observed in 71.4% of the patients followed by black dots. Conclusion: Alopecia lesions induced by radiation exposure during angioembolization shares common characteristic dermoscopy findings with alopecia areata and can be misconceived as alopecia areata without precise history taking. Its acute course and configuration, together with non-inflammatory biopsy results can help distinguish these two lesions.
P073 : Treatment of rare nodular fasciitis occurring on the face
( Byung Ho Oh ),( Ji Hee Kim ),( Zhen Long Zheng ),( Mi Ryung Rho ),( Kee Yang Chung ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2
Background: Surgical excision is generally recommended for the treatment of nodular fasciitis (NF) to rule out sarcoma. However, in rare cases of NF occurring on the face, non- surgical treatment and regular follow-up can be recommended considering surgical scar. Objectives: To evaluate the outcomes of surgical and non-surgical methods for the treatment of NF on the face. Methods: We performed a retrospective review of 16 patients diagnosed with NF on the face. Patients were treated with surgical excision or non-surgical methods such as triamcinolone intralesional injection (TA ILI) and pinhole method using a carbon dioxide (CO2) laser. Results: Among the 16 patients, surgical treatment was performed in nine cases and recurrence occurred in seven (77.8%, 7/9). Recurred lesions showed regression after repeated TA ILI. In five cases, pinhole method and repeated TA ILI resulted in regression. In one case, NF spontaneously regressed. On a visual analogue scale, pinhole treatment scored higher than surgical treatment. However, the values were not statistically significant (6.90±1.56 vs.5.61±1.36, p=0.163). Satisfaction level was lower in recurred patients. Conclusion: Surgical treatment for the NF on the face shows noticeable recurrence rate and results in scarring. Therefore, considering the possibility of spontaneous regression, non-surgical treatment should be recommended as the treatment of choice for NF on the face.
( Min Ju Choi ),( Do Young Kim ),( Su Hyun Cho ),( Zhen Long Zheng ),( Dong Wook Kim ),( Dong Sik Bang ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2
Background: Behcet`s disease (BD) is a chronic multisystemic vasculitis affecting blood vessels of any caliber or type. Recent evidence suggests that the clinical expression of BD is lessening. Objectives: Our aim was to examine the clinical expression of BD in Korea during the past three decades via a large patient registry. Methods: Initial manifestations of patients with BD seen at a tertiary referral hospital from 1983 to 2012 were reviewed retrospectively, stratifying patients by decade to compare epidemiologic data and cardinal symptoms. Results: A total of 3,674 patients with BD were reviewed. Significant proportionate declines occurred with respect to male gender, complete type of BD, and major presenting features (genital ulcers, ocular involvement, and skin lesions) whereas mean patient age rose progressively, as did frequencies of joint, gastrointestinal(GI), and central nervous system(CNS) manifestations (all p<0.0001). Conclusion: During the past three decades, clinical expression of BD in Korea has changed, resulting in fewer instances of complete type disease, declining male propensity, and shifting patterns of organ involvement.
P035 : Carpal tunnel syndrome in Behcet’s disease
( Su Hyun Cho ),( Do Young Kim ),( Min Ju Choi ),( Zhen Long Zheng ),( Hoon Park ),( Dong Sik Bang ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2
Background: Behcet`s disease (BD) is a chronic inflammatory disease characterized by orogenital ulcers, skin and ocular lesions, in addition to articular, vascular, and neurologic symptoms. Carpal tunnel syndrome (CTS), a peripheral neuropathy caused by compression of the median nerve, can also occur in BD patients secondary to inflammation in the connective tissues, vessels, and tendons, as well as nerve involvement in BD itself. However, reports of patients who have CTS in BD are rare. Objectives: The aim of this study was to evaluate the clinical characteristics of CTS in BD patients. Methods: Retrospective analysis of the medical records of 14 BD patients who were diagnosed with CTS was performed at the BD Specialty Clinic of Severance Hospital. Patient demographics, disease activity/severity for both diseases, and the clinical characteristics of CTS in BD were recorded and analyzed. Results: All 14 BD patients with CTS were women. Twelve patients (85.7%) were diagnosed with active BD. The CTS was mild in 8 patients (57.2%), moderate in 3 patients (21.4%), and severe in 3 patients (21.4%). Ten patients (71.4%) had BD prior to the diagnosis of CTS, and these 10 patients all had active BD. Conclusion: CTS can occur as a result of the inflammation associated with BD and can also be the presenting symptom of nerve involvement in BD. Therefore, a higher degree of suspicion should be maintained for CTS in patients with BD and vice versa; however, the exact relationship is uncertain.