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- 저자 : ( Yueh-min Huang ) (검색결과 5 건)
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Individual and common inhibitors of coronavirus and picornavirus main proteases
Kuo, Chih-Jung,Liu, Hun-Ge,Lo, Yueh-Kuei,Seong, Churl-Min,Lee, Kee-In,Jung, Young-Sik,Liang, Po-Huang Elsevier 2009 FEBS letters Vol.583 No.3
<P><B>Abstract</B></P><P>Picornaviruses (PV) and coronaviruses (CoV) are positive-stranded RNA viruses which infect millions of people worldwide each year, resulting in a wide range of clinical outcomes. As reported in this study, using high throughput screening against ∼6800 small molecules, we have identified several novel inhibitors of SARS-CoV 3CL<SUP>pro</SUP> with IC<SUB>50</SUB> of low μM. Interestingly, one of them equally inhibited both 3C<SUP>pro</SUP> and 3CL<SUP>pro</SUP> from PV and CoV, respectively. Using computer modeling, the structural features of these compounds as individual and common protease inhibitors were elucidated to enhance our knowledge for developing anti-viral agents against PV and CoV.</P>
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Home Energy Management System for Interconnecting and Sensing of Electric Appliances
( Wei-ting Cho ),( Chin-feng Lai ),( Yueh-min Huang ),( Wei-tsong Lee ),( Sing-wei Huang ) 한국인터넷정보학회 2011 KSII Transactions on Internet and Information Syst Vol.5 No.7
Due to the variety of household electric devices and different power consumption habits of consumers at present, general home energy management (HEM) systems suffer from the lack of dynamic identification of various household appliances and a unidirectional information display. This study presented a set of intelligent interconnection network systems for electric appliances, which can measure the power consumption of household appliances through a current sensing device based on OSGi platform. The system establishes the characteristics and categories of related electric appliances, and searches the corresponding cluster data and eliminates noise for recognition functionality and error detection mechanism of electric appliances by applying the clustering algorithm. The system also integrates household appliance control network services so as to control them according to users` power consumption plans or through mobile devices, thus realizing a bidirectional monitoring service. When the system detects an abnormal operating state, it can automatically shut off electric appliances to avoid accidents. In practical tests, the system reached a recognition rate of 95%, and could successfully control general household appliances through the ZigBee network.
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Frode Eika Sandnes,Yo-Ping Huang,Yueh-Min Huang 보안공학연구지원센터 2009 International Journal of Smart Home Vol.3 No.1
Hard disk-based personal video recorders have the capacity to store large quantities of video contents. A personal video recorder serving one household may have to cater for the diverse entertainment tastes imposed by different family members. Timer event programmed video recordings have a tendency to accumulate and it is difficult to access large video collections on current generation personal video recorders. This is because the recordings often are presented linearly in a chronologically ordered list that is accessed using the navigation keys on a remote control. In this study an alternative strategy for accessing large video collections via the navigation keys of a remote control is investigated. The strategy automatically clusters the video recording using cuts that are perceptually meaningful to the viewers and that minimize the retrieval effort. However, the results suggest that navigation keys do not meet the needs of large video collection browsing.
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Path Loss Exponent Estimation for Indoor Wireless Sensor Positioning
( Yu-sheng Lu ),( Chin-feng Lai ),( Chia-cheng Hu ),( Yueh-min Huang ),( Xiao-hu Ge ) 한국인터넷정보학회 2010 KSII Transactions on Internet and Information Syst Vol.4 No.3
Rapid developments in wireless sensor networks have extended many applications, hence, many studies have developed wireless sensor network positioning systems for indoor environments. Among those systems, the Global Position System (GPS) is unsuitable for indoor environments due to Line-Of-Sight (LOS) limitations, while the wireless sensor network is more suitable, given its advantages of low cost, easy installation, and low energy consumption. Due to the complex settings of indoor environments and the high demands for precision, the implementation of an indoor positioning system is difficult to construct. This study adopts a low-cost positioning method that does not require additional hardware, and uses the received signal strength (RSS) values from the receiver node to estimate the distance between the test objects. Since many objects in indoor environments would attenuate the radio signals and cause errors in estimation distances, knowing the path loss exponent (PLE) in an environment is crucial. However, most studies preset a fixed PLE, and then substitute it into a radio propagation loss model to estimate the distance between the test points; such method would lead to serious errors. To address this problem, this study proposes a Path Loss Exponent Estimation Algorithm, which uses only four beacon nodes to construct a radio propagation loss model for an indoor environment, and is able to provide enhanced positioning precision, accurate positioning services, low cost, and high efficiency.
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Design and Analysis of an Interactive Motion Simulator in Space Entertainment System
( Kuei-shu Hsu ),( Wei-ting Cho ),( Chin-feng Lai ),( Xiaofei Wang ),( Yueh-min Huang ) 한국인터넷정보학회 2012 KSII Transactions on Internet and Information Syst Vol.6 No.1
In this paper, the analysis and design of a motion simulator (based on the approach taken by interactive virtual reality (VR) entertainment systems) is conducted. The main components of the system include a bilateral control interface, simulation and a motion simulator control scheme. The space entertainment system uses a virtual environment that enables operators to feel the actual feedback sensing and distorted motion from the virtual environment, just as they would in the real environment. The space entertainment system integrates the dynamics of the motion simulator and the virtual environment and the operator maneuvers a steering wheel to interact with the system. The multiple bilateral control schemes employ a dynamical controller, which is designed by considering the velocity and acceleration that the operator imposes on the joystick, the environmental changes imposed on the motion simulator. In addition, we develop a calculated method to evaluate the Ratio of the simulation results. It is shown that the proposed control scheme can improve the performance of the visual entertainment system. Experiments are conducted on the virtual reality entertainment system to validate the theoretical developments.
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