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P135 : Analysis of the safety and efficacy of three natural extracts in cosmetics
( Yu Na Lee ),( Hae Jeong Youn ),( Min Jung Kim ),( Soo Young Kim ),( Nam Kyung Roh ),( Ho Jung Jung ),( Yu Ri Kim ),( Jae Wook Jung ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2
Background: The function of sebum in human is reducing water loss from the skin``s surface and protecting the skin from infection by microorganism. However, when there is excessive secretion of sebum, it will cause black heads and expansion of the pores so that waste will be accumulated. Objectives: To develop cosmetics for sebum removal and pore improvement that can improve limitations of the existing products. The ingredients include Diospyros kaki (D. kaki ), Castanea crenata (C. crenata), and Polygonum cuspidatum (P. cuspidatum) and to verify the safety and human efficacy evaluation. Methods: Bacteria microbial limit test and patch test performed with 31 participants. Also, with 23 participants who have oily skin, efficacy evaluation was performed. Changes in the amount of sebum, moisture, dead skin condition, blackhead, skin roughness between before and after the test were compared for control group. Results: As a result of safety assessment, there was no pathogenic microorganism for microbial limit test and, there was no skin reactions for patch test. For changes in the amount of sebum and black head from efficacy evaluation,there was temporary improvement for the experimental group. For the amount of moisture, dead skin, and skin roughness of the experimental group showed improvement. Conclusion: When being complemented with body application test for long-term usage, they can be used as natural ingredients when cosmetic manufacturers or sellers are developing new products.
P226 : Sensitive skin in Korean population
( Yu Ri Kim ),( Hae Jeong Youn ),( Min Jung Kim ),( Soo Young Kim ),( Nam Kyung Roh ),( Ho Jung Jung ),( Jae Wook Jung ),( Yu Na Lee ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2
Background: Sensitive skin is characterized by the occurrence of sensations of tingling, prickling, heat, burning, pain or itching and, on occasion, erythema in response to multiple physical, chemical or hormonal factors that do not have irritant properties by themselves. Objectives: This study sought to identify the proportion of sensitive skin and their charicteristics in Korean population. Methods: Representative nationwide samples of the Korean populations aged 18 and over were selected. The individuals were questioned by telephone and selected as per the quotas method. Results: Among the 1000 individuals, 55.3% of men and 59.4% of women answered “sensitive” or “very sensitive”. The difference between the 2 sexes is significant (p<0.02). The sensitive skin group are 2 to 4 times more to declare dermatosis, and are 2 or 3 times more reactive to environmental factors, cosmetics and food intake compared with the non-sensitive skin group. Conclusion: 56.8% of Korean appear to have sensitive skin. It is the highest prevalence among the countries reporting theirs. Respondents complaining of sensitive skin appeal more reactive skin to unexpected factors than those with non-sensitive skin. Dermatologists should therefore routinely question their patients’ skin sensitivity and provide them more care.
Relationship between Gait, Static Balance, and Pelvic Inclination in Patients with Chronic Stroke
( Yu-won Choe ),( Kyu-ryeong Kim ),( Myoung-kwon Kim ) 대한물리의학회 2021 대한물리의학회지 Vol.16 No.1
PURPOSE: This study examined the correlations between gait, static balance, and pelvic inclination in patients with chronic stroke. METHODS: Twenty-two chronic stroke patients were included in this study. The subjects participated in gait, static balance, and pelvic inclination tests. In the gait measurement, the cadence and gait velocity were measured, and the average of three trials was calculated and recorded. The static balance was measured using a force platform. The data was captured for ten seconds, and five successful trials were recorded. Pelvic inclination in the sagittal plane was measured using a palpation meter. For data processing, a KolmogorovSmirnov test was used to determine the type of distribution for all variables. Pearson's correlation coefficient was used for correlation analysis. The correlations among the gait, static balance, and pelvic inclination was calculated. The level of significance was .05. RESULTS: Significant negative correlations were observed between the gait variables (cadence, velocity) and static balance variables (COP path length, COP average velocity, and 95% confidence ellipse area) (p < .05). On the other hand, there was no significant correlation between pelvic inclination and gait or between the pelvic inclination and static balance variables. CONCLUSION: Significant correlations were observed between the gait function and static balance. On the other hand, there were no significant correlations between the pelvic inclination and gait and static balance. These results suggest that the pelvic inclination is not an important consideration for increasing the gait function and static balance.
( Yu-won Choe ),( Myoung-kwon Kim ) 대한물리의학회 2018 대한물리의학회지 Vol.13 No.3
PURPOSE: This study was conducted to identify the effects of sympathetic conversation on stress, anxiety and depression, and muscle tone in chronic stroke patients. METHODS: Patients were randomly assigned to either an experimental group (EG, n=7) or control group (CG, n=7). Both groups participated in a pretest before intervention. Subjects were asked to undergo: 1) electroencephalogram, 2) Stress Response Inventory, 3) Hospital Anxiety and Depression Scale, 4) muscle tone and stiffness testing. After the pretest, EG received sympathetic conversation and CG received a simple explanation about stroke recovery and rehabilitation. Following the intervention, both groups were immediately administered a post test. RESULTS: In EG, the electroencephalogram relative alpha power was significantly increased (p<.05), while the electroencephalogram relative gamma power was significantly decreased (p<.05). The Stress Response Inventory and Hospital Anxiety and Depression Scale scores decreased significantly in both groups (p<.05). In addition, muscle tone and stiffness decreased significantly in the EG (p<.05) CONCLUSION: The results of the present study indicate that sympathetic conversation had a positive effect on stress, anxiety and depression, and muscle tone in patients with chronic stroke. Therefore, sympathetic conversation could be used to improve not only psychological problems in chronic stroke patients including stress and anxiety, but also physical conditions including muscle tone.
New-onset of palmoplantar pustulosis while on adalimumab treatment for ankylosing spondylitis
( Yu Na Lee ),( Ho Jung Jung ),( Yu Ri Kim ),( Jae Wook Jung ),( Hyun Jung Park ),( Hyung Jin Hahn ),( Young Ji Hwang ),( Ji Young Kim ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ) 대한피부과학회 2012 대한피부과학회 학술발표대회집 Vol.64 No.1
P279 : The effects of freeze dried extract of dangyuja (citrus grandis osbeck) on melanogenesis
( Yu Na Lee ),( Hae Jeong Youn ),( Min Jung Kim ),( Soo Young Kim ),( Nam Kyung Roh ),( Ho Jung Jung ),( Yu Ri Kim ),( Jae Wook Jung ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2
Background: Although previous studies have identified that both the fruit and leaf of dangyuja (Citrus grandis Osbeck) exhibits anticancer, antioxdant and anti-inflammatory effect, the inhibitory effect of melanogenesis have not been reported. Objectives: In this study, freeze dried extract of dangyuja was evaluated for their potential to inhibit melanogenesis. Methods: Cytotoxicity and melanin content in mouse B16F10 melanoma cells were assayed after treatment with the freeze dried extracts of dangyuja. Results: Freeze dried extracts of dangyuja strongly decreased the tyrosinase activity for catalysis of L-dihydroxyphenylalanine (L-DOPA) oxidation in a dose- dependent manner. The results demonstrate that extracts possessed low cytotoxic activity and that melanin content was reduced. Conclusion: Freeze dried extracts of dangyuja is a safe natural materials that show an effective inhibition of melanogenesis. These results suggest that freeze dried extracts of dangyuja can be considered as an effective skin whitening reagent for application in cosmetics.
( Yu Ri Kim ),( Hae Jeong Youn ),( Min Jung Kim ),( Soo Young Kim ),( Nam Kyung Roh ),( Ho Jung Jung ),( Jae Wook Jung ),( Yu Na Lee ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2
Background: Ketoconazole or zinc-pyrithione shampoos are common treatments for scalp seborrheic dermatitis. However, shampoos comprising different compounds are required to provide patients with a wider range of treatment options. Objectives: To evaluate a new-formula shampoo that contains natural ingredients, extract of Rosa centifolia petals and epigallocatechin gallate (EGCG), that exert antioxidative, anti-inflammatory and sebum secretion inhibitory effects, and antifungal agents for the treatment of scalp seborrheic dermatitis. Methods: Seventy-five patients were randomized into three groups: new-formula shampoo, 2% ketoconazole shampoo and 1% zinc-pyrithione shampoo. Clinical severity scores, sebum levels, user satisfaction and irritation were assessed at week 0, week 2 and week 4 after.Results: The efficacy of the new-formula shampoo was comparable to that of both the 1% zinc-pyrithione shampoo and the 2% ketoconazole shampoo. Furthermore, it was found to provide a more rapid response than the 1% zinc-pyrithione shampoo for mild erythema lesions and was associated with greater user satisfaction compared to the 2% ketoconazole shampoo. However, the new-formula shampoo did not exhibit the previously reported sebum inhibitory effect. Conclusion: Extract of Rosa centifolia petals or EGCG could be useful ingredients in treatments for scalp seborrheic dermatitis.