The structural and non–linear dynamic analysis for radioactive waste container

Shen Yu-Yu,Cheng Kuei-Jen,Chou Hsoung-Wei 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.8

In recent years, the development of radioactive waste containers for nuclear facility decommissioning and dismantling is a critical issue because the Taiwan domestic boiling water reactor nuclear power plant is going to be decommissioned. The main purpose of this research is to design a metal container that meets the structural requirements of related regulations. At first, the shielding analysis was performed by varying dimensions of radioactive waste to determine the storage efficiency of the container. Then, a series of structural analyses for operational and accidental conditions of the container with full load were conducted, such as lifting, stacking, and drop impact conditions. On the other hand, the field drop impact tests were carried out to ensure structural integrity. The present research demonstrates the structural safety of the developed container for decommissioned nuclear facilities in Taiwan.

Molecular cloning and expression analysis of the first two key genes through 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway from Pyropia haitanensis(Bangiales, Rhodophyta)

Yu Du,Jian Guan,Ruijun Xu,Xin Liu,Weijie Shen,Yafeng Ma,Yuan He,Songdong Shen 한국조류학회I 2017 ALGAE Vol.32 No.4

Pyropia haitanensis (T. J. Chang et B. F. Zheng) N. Kikuchi et M. Miyata is one of the most commercially usefulmacroalgae cultivated in southeastern China. In red algae, the biosynthesis of terpenoids through 2-C-methyl-Derythritol4-phosphate (MEP) pathway can produce a direct influence on the synthesis of many biologically importantmetabolites. In this study, two genes of cDNAs, 1-deoxy-D-xylulose-5-phosphate synthase (DXS) and 1-deoxy-Dxylulose-5-phosphatereductase (DXR), which encoding the first two rate-limiting enzymes among MEP pathway werecloned from P. haitanensis. The cDNAs of P. haitanensis DXS (PhDXS) and DXR (PhDXR) both contained complete openreading frames encoding polypeptides of 764 and 426 amino acids residues, separately. The expression analysis showedthat PhDXS was significant differently expressed between leafy thallus and conchocelis as PhDXR been non-significant. Additionally, expression of PhDXR and its downstream gene geranylgeranyl diphosphate synthase were both inhibitedby fosmidomycin significantly. Meanwhile, we constructed types of phylogenetic trees through different algae and higherplants DXS and DXR encoding amino acid sequences, as a result we found tree clustering consequences basically in linewith the "Cavalier-Smith endosymbiotic theory." Whereupon, we speculated that in red algae, there existed only completeMEP pathway to meet needs of terpenoids synthesis for themselves; Terpenoids synthesis of red algae derivativesthrough mevalonate pathway came from two or more times endosymbiosis of heterotrophic eukaryotic parasitifer. Thisstudy demonstrated that PhDXS and PhDXR could play significant roles in terpenoids biosynthesis at molecular levels. Meanwhile, as nuclear genes among MEP pathway, PhDXS and PhDXR could provide a new way of thinking to researchthe problem of chromalveolata biological evolution.

Arabidopsis nucleoside diphosphate kinase-2 as a plant GTPase activating protein

( Yu Shen ),( Yun Jeong Han ),( Jeong Il Kim ),( Pill Soon Song ) 생화학분자생물학회 2008 BMB Reports Vol.41 No.9

Oxalate Decarboxylase from Agrobacterium tumefaciens C58 is Translocated by a Twin Arginine Translocation System

( Yu Hu Shen ),( Rui Juan Liu ),( Hai Qing Wang ) 한국미생물 · 생명공학회 2008 Journal of microbiology and biotechnology Vol.18 No.7

Clinical outcomes on tension-releasing suture appendage on single-incision sling devices for postoperative voiding dysfunction involving undue tape tension

( Yu-hua Shen ) 대한산부인과학회 2019 대한산부인과학회 학술대회 Vol.105 No.-

Objective: To determine the clinical outcomes of adding tension releasing suture(TRS) appendage for manipulation of over-tensioned single-incision slings(SIS) as a means to relieve post-operative voiding dysfunction. Material and Method: This was a retrospective case series study conducted in the in a tertiary referral center from January 2010 to July 2017 after gaining Institutional Review Board approval. The records of patients with urodynamic stress incontinence(USI) without needing concurrent procedures that underwent anti-incontinence surgery using MiniArc, Solyx, and Ajust with voiding dysfunction were collated and analyzed. The primary outcome measure was the recovery of normal post-void residual urine(PVR) after TRS manipulation. The secondary outcome measures were the pain intensity noted during manipulation (quantified through Visual Analog Scale), and the continence rate (assessed through 1. Objective cure- 1-hour pad test weight <2g and absence of USI; and 2. Subjective cure- index score of <1 on question #3 on UDI-6: "Urine leakage related to physical activity, coughing, or sneezing?"). Results: There were 73 patients with high post-void residual (PVR) urine. The forty-two(9.5%) patients with over-tensioned sling were managed with TRS manipulation while the 31 patients(7%) with high PVR and no sling over-tension were managed with intermittent catheterization. All patients in both groups regained normal PVR. The TRS manipulated group demonstrated an objective cure of 92.9%(39/42) and subjective cure of 91%(38/42). Pain experienced during TRS manipulation significantly increased with the Ajust system (p=0.018). There were 3 patients who had persistence of USI, 2 from MiniArc and 1 from Solyx. Conclusion: The TRS manipulation is a well-tolerated procedure that can effectively relieve voiding dysfunction for over-tensioned SIS without affecting continence cure rates.

Cytokeratin 15 is an Effective Indicator for Progression and Malignancy of Esophageal Squamous Cell Carcinomas

Shen, Yu-Hong,Xu, Cui-Ping,Shi, Zhi-Meng,Zhang, Yan-Jiao,Qiao, Ya-Guang,Zhao, He-Ping Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.9

Purpose: To compare the expression level of CK 15 in normal esophageal and esophageal squamous-cell carcinoma (ESCC) tissues and analyse possible functions of CK15 in occurrence and development. Materials and Methods: Immunohistochemistry was used to compare CK14, CK15 and proliferating cell nuclear antigen (PCNA) expression levels in ESCCs. Expression level of CK15 was also assessed by Western blotting. In addition, levels of CK15, cytokeratin 19 fragment antigen 21-1 (CYFRA21-1) and PCNA were detected in serum by enzymelinked immunosorbent assay (ELISA) and chemiluminescence methods. Relationships between clinicopathological parameters and CK14 and CK15 expression were then analyzed. Results: According to immunohistochemistry, in esophageal and intraepithelial neoplasia (SIN) tissues, the expression of CK14, CK15 and PCNA localized to basal layer of the epithelium. CK14 and CK15 levels were higher in normal esophageal squamous epithelial tissue than in SIN and ESCC, and greater in highly differentiated than poorly differentiated carcinoma tissue. By Western blotting, we found more pronounced expression of CK15 in normal esophageal tissue, compared with carcinoma tissue. The specificity of changed CK15 and CYFRA21-1 expression was respectively 90.0% and 96.7% in serum of ESCC patients. Joint detection could improve the sensitivity of esophageal carcinoma diagnosis. Relationships between CK14, CK15 expression and clinical parameters were not statistically significant (P>0.05). Postoperative survival in patients of CK14, CK15 positive expression was longer than with negative expression ($x^2=4.35$, P=0.037; $x^2=9.852$, P=0.002). Conclusions: CK15 expression decreased in esophageal squamous cell carcinoma tissue and serum of esophageal squamous carcinoma patients. We infer that CK15 may play an important role for the occurrence and development of esophageal squamous-cell carcinoma. In the future, CK15 may be used for the diagnosis, treatment and prognostic evaluation of esophageal squamous-cell carcinoma.

Facile synthesis of Nafion-supported Pt nanoparticles with ultra-low loading as a high-performance electrocatalyst for hydrogen evolution reaction

Yu, Jianguo,Wei, Dan,Zheng, Zhe,Yu, Wenjie,Shen, Honghui,Qu, Yuning,Wen, Shuya,Kwon, Young-Uk,Zhao, Yongnan Elsevier 2020 JOURNAL OF COLLOID AND INTERFACE SCIENCE - Vol.566 No.-

<P><B>Abstract</B></P> <P>x%Pt-Naf-CV (Pt-Nafion-Cyclic Voltammetry) catalysts with homogeneously distributed platinum nanoparticles and ultra-low Pt loading are successfully synthesized by using a facile potential cycling approach. The as-synthesized 0.8%Pt-Naf-CV catalyst exhibits an enhanced electrocatalytic activity for hydrogen evolution reaction (HER) in 0.5 M H<SUB>2</SUB>SO<SUB>4</SUB> solution, which obtains a low overpotential of 34 mV at 10 mA cm<SUP>−2</SUP>. The linear sweep voltammetry (LSV) curve of 0.8%Pt-Naf-CV catalyst is almost consistent with that of commercial Pt/C. However, the 0.8%Pt-Naf-CV catalyst displays a more excellent stability and durability in comparison with commercial Pt/C. Besides, the Pt loading of Pt/C (Pt–10 wt%) is about 10 times that of 0.8%Pt-Naf-CV catalyst. The improved electrocatalytic performances are derived from the synergistic effects of Pt and Nafion. The Nafion plays a significant role as a dispersant, carrier and structure directing agent on the morphology and size of the Pt catalyst. This result contributes a promising method to enhance the catalytic activity and reduce the amount of Pt.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Aberrant Methylation of RASSF1A gene Contribute to the Risk of Renal Cell Carcinoma: a Meta-Analysis

Yu, Gan-Shen,Lai, Cai-Yong,Xu, Yin,Bu, Chen-Feng,Su, Ze-Xuan Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.11

The aim of this study was to assess the diagnostic value of RASSF1A methylation in renal cell carcinoma. Systematically search were performed using the Pubmed, ProQest and Web of Science for all articles on the association between RASSF1A methylation and renal cell carcinoma before 15 April 2015. After the filtration, 13 studies involving 677 cases and 497 controls met our criteria. Our meta-analysis suggested that hypermethylation of RASSF1A gene was associated with the increased risk of RCC(OR:4.14, 95%CI:1.06-16.1). Stratified analyses showed a similar risk in qualitative detection method(OR:28.4, 95%CI:10.2-79.6), body fluid sample(OR:12.8, 95%CI:5.35-30.8), and American(OR:10.5, 95%CI:1.97-55.9). Our result identified that RASSF1A methylation had a strong potential in prediction the risk of Renal cell carcinoma.

A Noisy Infrared and Visible Light Image Fusion Algorithm

( Yu Shen ) 한국정보처리학회 2021 Journal of information processing systems Vol.17 No.5

To solve the problems of the low image contrast, fuzzy edge details and edge details missing in noisy image fusion, this study proposes a noisy infrared and visible light image fusion algorithm based on non-subsample contourlet transform (NSCT) and an improved bilateral filter, which uses NSCT to decompose an image into a low-frequency component and high-frequency component. High-frequency noise and edge information are mainly distributed in the high-frequency component, and the improved bilateral filtering method is used to process the high-frequency component of two images, filtering the noise of the images and calculating the image detail of the infrared image’s high-frequency component. It can extract the edge details of the infrared image and visible image as much as possible by superimposing the high-frequency component of infrared image and visible image. At the same time, edge information is enhanced and the visual effect is clearer. For the fusion rule of low-frequency coefficient, the local area standard variance coefficient method is adopted. At last, we decompose the high- and low-frequency coefficient to obtain the fusion image according to the inverse transformation of NSCT. The fusion results show that the edge, contour, texture and other details are maintained and enhanced while the noise is filtered, and the fusion image with a clear edge is obtained. The algorithm could better filter noise and obtain clear fused images in noisy infrared and visible light image fusion.

robust sliding mode controller design for a ball screw table driven by an air motor

Yu-Ta Shen,Yean-Ren Hwang,Chia-Sheng Cheng 대한기계학회 2009 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.23 No.11

Air motors are often applied in the automation industry in areas with special requirements, such as in sparkprohibited environments, the mining industry, chemical manufacturing plants, and similar locations. The purpose of this study is to analyze the behaviors of a ball screw table powered by a vane-type air motor and to design a robust sliding mode controller for the inlet pressure. The rotational speed of the air motor is closely related to the pressure and flow rate of the compressed air. Furthermore, the compressibility of the air and the friction in the mechanism mean that the overall system is nonlinear, with fluctuating input. A robust sliding mode control is developed to overcome the effects of variations in the inlet pressure and air leakage problems. The experimental results validate the robustness of the proposed position control strategy.