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      • Comparison of cortical bone thickness and root proximity at maxillary and mandibular interradicular sites for orthodontic mini-implant placement

        Lim, JE,Lee, SJ,Kim, YJ,Lim, WH,Chun, YS Blackwell Publishing Ltd 2009 Orthodontics & craniofacial research Vol.12 No.4

        <P>Structured Abstract</P><P>Authors – </P><P>Lim JE, Lee SJ, Kim YJ, Lim WH, Chun YS</P><P>Objectives – </P><P>To compare maxillary and mandibular cortical bone thickness and rootic proximity for optimal mini-implant placement.</P><P>Setting and Sample Population – </P><P>CT images from 14 men and 14 women were used to evaluate buccal interradicular cortical bone thickness and root proximity from mesial of the central incisor to the 2nd molar. Cortical bone thickness was measured at 0°, 15°, 30°, and 45° angles relative to the root surface using three-dimensional images.</P><P>Results – </P><P>For the cortical bone thickness, there was no statistically significant difference between the maxilla and the mandible in the anterior area; however, there was a significant difference in the posterior area. Cortical bone in the maxilla, mesial and distal to canine interradicular sites, was thickest while thickness in the mandible exhibited a gradual anterior to posterior increase. Cortical bone thickness in the maxilla increased as both level and angle increased, while the cortical bone thickness in the mandible was greatest at 4 mm from the alveolar crest. Root proximity mesial and distal to 2nd premolar interradicular sites was greatest.</P><P>Conclusion – </P><P>Based on our results, cortical bone thickness depends on the interradicular site rather than sex or individual differences.</P>

      • Role of NAD(P)H oxidase in the tamoxifen-induced generation of reactive oxygen species and apoptosis in HepG2 human hepatoblastoma cells

        Lee, YS,Kang, YS,Lee, SH,Kim, JA 영남대학교 약품개발연구소 2001 영남대학교 약품개발연구소 연구업적집 Vol.11 No.-

        Previously, tamoxiten (TAM) has been shown to induce apoptosis through elevation of intracellular Ca^(2+) in HepG2 human hepatoblastoma cells. In this study we investigated the role of reactive oxygen species (ROS) in the TAM-induced apoptosis, and interrelationship between intracellular Ca^(2+) and ROS. TAM induced a slow and sustained increase in intracellular ROS level. An antioxidant, N-acetlycysteine signlficantly inhibited both ROS production and apoptosis induced by TAM, suggesting that ROS may play an essential role in the TAM-lnduced apoptosis. In a time frame ROS generation followed lntracellular Ca^(2+) increase, and the extracellular and intracellular Ca^(2+) chelation with EGTA and BAPTA/AM, respectively, completely inhibited the TAM-induced ROS production, lndicating that intracellular Ca^(2+) may mediate the ROS generation. Inhibitors of NAD(P)H oxidase, diphenylene iodonium, phenylarsine oxide and neopterine, signlficantly blocked the TAM-induced ROS generation and apoptosis, implying that this oxidase may act as a source enzyme for the production of ROS. These results suggest that non-phagocytic NAD(P)H oxidase may paly a novelroleas a mediator of the apoptosis associated with intracellular Ca^(2+) in HepG2 cells. Cell Death and Differentiation (2000)7,925-932.

      • KCI등재

        이형성 생식선에서 방생한 혼합생식세포종 1 예

        이승호,이두진,이태형,이영기,배철준,곽양수,이용훈,김미진 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.7

        Gonadal tumors occur in a small percentage of patients who are diagnosed as having gonadal dysgenesis. Most of the tumors were gonadoblastomas and dysgerminomas. We present here with brief review of literature one case of mixed germ cell tumor of phenotycally typical female without sexual ambiguity who presented with primary amenorrhea, short stature and minimal abnormal somatic features, whose chromosome analysis showed 45,X/ 46,X, +mar karyotype.

      • KCI등재

        임신중 자궁손상에 대한 임상적 관찰

        이영순(YS Lee),이지신(JJ Lee),이경선(KH Lee) 대한산부인과학회 1968 Obstetrics & Gynecology Science Vol.11 No.5

        Perforation and rupture of the uterus are dangerous complications of pregnancy which often result in death of the mother and fetus. We observed damage of the gravid uterus during the period from Jan. in 1963 to March in 1968. Uterine perforation due to termination of pregnancy occured 14 cases, and uterine rupture of previous cesarean scar, traumatic and sponaneous uterine rupture of the intact uterus occurred 3, 8 and 3 cases, respectively.

      • KCI등재

        미세침윤 자궁경암의 세포진

        이윤성(YS Lee),구본수(BS Koo),정성희(SH Chung),박종근(JK Park),이승호(SH Lee),이태호(TH Lee) 대한산부인과학회 1983 Obstetrics & Gynecology Science Vol.26 No.5

        자궁경질부 원추절제에서 확진된 36예의 미세침윤경암의 세포진 소견을 검토한 바 그 성적을 아래와 같이 요약할 수 있었다. 미세침윤경암의 핵염색질은 coarse pattern이 61.6%,fine pattern이 38.9%이었다. 세포다형성은 경도가 58.3%, 중등도가 16.7%, 고도가 25.0%이었다. 악성세포의 군집성은 경도가 38.9%, 중등도가 16.7%, 고도가 44.4%이었다. 세포진 배경은 clear가 61%로 가장 많았고 이하 출혈이 33.3%, 염증이 19.4%, necrotic debnis가 8.3%의 순이었다. 각 예별 최다악성세포출현 빈도는 large cell nonke-ratinizing type 이 16예로 44.4%로 가장 많았고, 이하keratinizing cancer cell type의 25.0%, clustered iso-diametric cancer cell type의 13.9%, fiber cell의 8.3%, small cancer cell의 2.8%, undifferentiated can-cer cell의 2.8%, parabasal dyskaryotic cell의 순이었다. 상기한 세포상의 특징 등으로 조직 진단을 추정하였을 때 그 성적은 dysplasia가 1예로 2.8%, CIS가 10예로 27.8%, microinvasive가 16예로 44.4%, invasive가 9예로 25.0%이었다. Studies were made on cytologic pictures in 36 cases of microinvasive ca. of ute- rine cervⅸ which were diagnosed by cone biopsy. The results summerized were as follows: There was 61.6% of coarse chromatin pattern and 38.9% of fine chromatin pattern. Regarding to the pleomorphism distribution of degree of slight, moderate and extensive were 58.3%, 16.7% and 25.0% respectively. Degree of aggregation in malignant Cells, slight, moderate and extensⅳe was 38.9%, 16.7% and 44.4% respectively, Cytologic back ground in smears from microinvasive ca. of uterine cerⅵx, the most frequently encountered was clear pattern, which revealed 61.0% and in order of bleeding pattern 33.3%, infection pattern 19.4% and necrotic debris pattern 8.3%. The distribution of predominant malignant cell type in each of 36 cases was large cell keratinizing type showed 44.4% and in order of keratinizing ca. cell type 25.0%, clustered isodiametric cell type 13.9%, fiber cell type 8.3% and small ca. cell type, undifferentiated and parabasal dyskaryotic cell type 2.8% each respectively. . When diagnosis was predicted with histologically proved microinvasive ca. of uterine cerⅵx through the characteristics of cytology pattern, dysplasia, ClS, mic- .roinvasⅳe and invasive ca. was 2.8%, 27.8%, 44.4% and 25.0% respectⅳely.

      • KCI등재

        Magnetic properties and structural orderliness of CoAl alloy films

        YS Lee,HJ Shin,IY Park,KW Kim,YP Lee 한국물리학회 2004 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.45 No.1

        The magnetic properties and the local atomic structures of ordered and disordered CoxAl1alloy lms were investigated by using VSM and Co K-edge X-ray absorption spectroscopy measurements, respectively. From the VSM result, the saturation magnetization is enhanced and Hc (= right Hc - left Hc) is decreased when orderedness weakens and Co content increases. From the analysis of Co K-edge absorption spectra, the Co atoms in disordered lms and Co-rich alloy lms predominantly occupy Al-type sites, in contrast to ordered and equiatomic CoAl alloy lms. Therefore, the probability of anti-structure Co and/or cluster formation increases as the disorderliness is enhanced and the Co concentration increases. Finally, we found that weakened orderedness and/or an increase in Co content in -phase Co-Al alloy lms led to the enhancement of the magnetization and reduction of Hc; due to the formation of Co clusters.

      • KCI등재

        초음파에 의해 진단된 결합쌍태아 2 예

        이국,이윤호,문태일,조용선,오연수,박정식 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.9

        결합쌍태임신은 일란성 쌍태임신의 희귀한 합병증의 하나로서 초음파진단술의 발달이 이루어지기 전에는 대부분의 경우에 있어서 임신 말기에 시행한 재래식 방사선 골반계측을 시행하는 도중에 우연히 발견되어지거나 분만이 임박하여 발견되곤 하였다. 비교적 최근에 들어서야 초음파진단기기의 발달로 말미암아 상당히 정확히 결합쌍태임신을 산전 진단할 수 있게되었다. 이에 따라 결합쌍태아를 임신 초기에 진단하고 이와 더불어 결합의 정도를 파악하는 것이 산과적 처치를 수행하는 데 있어 중요한 요소가 되었다. 이런 배경 하에 저자 등은 최근에 경험한 결합쌍태임신 2예를 간단한 문헌 고찰과 더불어 보고하고자 한다. Conjoined twin is one of rare complications of monozygotic multiple pregnancy. Before the age of ultrasonography, this rare complication could hardly be recognized until the process of labor progressed. Recently, with the developement of ultrasonogrphy, we can diagnose conjoined twins in any stage of pregnancy with considerable accuracy. Early prenatal diagnosis and assessment of the degree of conjoining is essential for obstetrical counseling and management. Recently we have experienced two cases of conjoined twins diagnosed by ultrasonography during the second trimester, and report that with brief review of related literatures.

      • KCI등재

        대망임신 1 례

        이원명,이주명,석지혜,이흥관,최윤석,김익수 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.11

        Omental pregnancy is an extremely rare form of abdominal pregnancy that may cause life threatening massive hemorrhage in case of rupture. It may occur by primary implantation of the fertilized ovum in the omentum. The diagnosis is very difficult, but prompt surgical intervention is required when it is suspected, because perinatal mortality and maternal mortality in abdominal pregnancy were 85∼95% and 0.5∼6%. We experienced a case of omental pregnancy in the first times and reported it with brief review of literature.

      • SCISCIESCOPUS

        Parthenogenetic Induction of Canine Oocytes by Electrical Stimulation and Ca-EDTA

        Lee, SR,Kim, J-W,Kim, BS,Yoo, D-H,Park, YS,Lee, T-H,Ha, J-H,Hyun, B-H,Ryoo, ZY Blackwell Publishing Ltd 2009 REPRODUCTION IN DOMESTIC ANIMALS Vol.44 No.5

        <P>Contents</P><P>In this study, we investigated parthenogenetic induction of canine oocytes by electrical stimulation following Ca-EDTA treatment. Oocyte maturation, parthenogenetic development, and cleavage rate in canine after various electrical stimulations (1.5, 1.8, 2.1 kV/cm) for 50 &mgr;s with single DC pulse following 1 mM Ca-EDTA treatment were investigated. In oocyte activated electrically at the voltage of 1.5 kV/cm after 1 mM Ca-EDTA treatment, the rate of pronucleus and two-cell was 4.1% and 2.7%, respectively. Although electrical stimulation could parthenogenetically induce immature oocyte to cleavage stage, degeneration rate in all experimental groups was more than 60%. This means that electrical stimulation after Ca-EDTA treatment could cause canine oocytes to be degenerated. However, two-cell in canine oocyte by parthenogenesis was for the first time induced. Therefore, we suggested that electrical stimulation for canine oocytes could induce parthenogenetically early embryonic cleavage. This result can be used as a basic data for parthenogenesis study in canine. Also, to perform more developed embryonic development, further study to parthenogenesis in canine need to be developed.</P>

      • SCOPUSKCI등재

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