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Youngmi Lee,Mi-Hyun Kim,Jae Eun Shim,Haeryun Park 한국영양학회 2020 Nutrition Research and Practice Vol.14 No.6
BACKGROUND/OBJECTIVES: This study aimed to improve portion size estimation aids (PSEAs) used in the nutrition survey of the Korea National Health and Nutrition Examination Survey (KNHANES) and validate the accuracy and precision of the newly developed aids. SUBJECTS/METHODS: We conducted intensive interviews with survey experts in KNHANES and consulted with experts to collect opinions about improvement of PSEAs. Based on the results of the interviews, 5 types of PSEAs (rice bowl, earthen pots, mounds, measuring spoons, and thickness sticks) were newly developed using 3-dimensional (3D) modeling or modification of color or shape. Validation tests were conducted with 96 adults 20 years old or older. For the rice bowl and earthen pots, the participants were asked to select the more similar PSEA in size after being shown the real dishes. For the mounds, measuring spoons, and thickness sticks, the participants were presented with actual plates of food and asked to estimate the given portion sizes using the given PSEAs. RESULTS: The improved 2-dimensional (2D) picture aid for the rice bowl reflecting the size distortion by angle of view using 3D modeling was perceived more closely to the actual size than the current 2D picture (P < 0.001). The change of the color of 2D pictures and 3D models, the change of shape of the measuring spoons, and the 3-dimensionalization of the 2D mounds had no significant improvement in the subjects" perception. CONCLUSIONS: The currently used 2D PSEAs need to be fully redesigned using 3D modeling to improve subjects" perception. However, change of color or shape will not be necessary. For amorphous foods, it is suggested that more evaluation be performed before reaching a final conclusion in the use of PSEAs, or alternative ways to improve accuracy of estimation need to be explored.
정주혜,Eun Youngmi,옥선명,Kim Bo-Kyung,Kim Tae-Hong,Kim Donghyeon,Park Se Jin,임민균,김세홍 대한신경정신의학회 2022 PSYCHIATRY INVESTIGATION Vol.19 No.9
Objective Religious behaviors are considered as complex brain-based phenomena that may be associated with structural brain change. To identify the pattern of regional brain volume change in nuns, we investigated structural alterations in the brains of nuns using a fast processing automated segmentation method based on deep learning algorithms.Methods We retrospectively reviewed the medical records of the catholic sisters between the ages of 31 and 80 who are members of the charity of St. Vincent de Paul of Korea. A total of 193 asymptomatic subjects (86 nuns and 107 control subjects) received comprehensive health screening and underwent brain MRI scans. We compared cortical and sub-cortical volume between groups across multiple locations using our in-house U-Net++ deep learning-based automatic segmentation tool.Results Compared to the control group, the nun group displayed increased gray matter volume in the right lingual cortex, left isthmus-cingulate, posterior-cingulate, rostral-middle-frontal, superior-frontal, supramarginal, temporal-pole cortices, and bilateral pars-triangularis cortices after correction for multiple comparisons. On the other hand, the nun group showed reduced gray matter volume in the temporal and parietal regions relative to healthy controls.Conclusion Our study suggests that spiritual practice may affect brain structure, especially in several frontal regions involved in a higher level of insight function.
Exposure to tetrabromobisphenol A induces cellular dysfunction in osteoblastic MC3T3-E1 cells
Choi, Eun Mi,Suh, Kwang Sik,Rhee, Sang Youl,Oh, Seungjoon,Kim, Sung Woon,Pak, Youngmi Kim,Choe, Wonchae,Ha, Joohun,Chon, Suk Taylor Francis 2017 Journal of environmental science and health. Part Vol.52 No.6
중년기의 자기효능감, 우울인지, 건강상태 및 건강증진행위의 경로분석
윤은자(Eun Ja Yeun),김희정(Heejeong Kim),전미순(Misoon Jeon),권영미(Youngmi Kwon) 한국생활환경학회 2013 한국생활환경학회지 Vol.20 No.1
The purpose of the study is to examine path analysis of self efficacy, depressive cognition, health status and health promotion behavior of middle aged adults. The research design was a descriptive survey study, and 310 selected through convenience sampling in middle aged adults. There was statistically significant difference in self efficacy, health status and health promotion behavior according to socio-demographic characteristics. In particular, there was statistically significant difference in self efficacy according to religion(F = 2.166, p = .031) and economic status(F = 3.617, p = .028), in health status according to education(F = 3.799, p = .023), marital status(F = 8.237, p < .001) and economic status(F = 18.112, p < .001), and in health promotion behavior according to sex(t = ?2.323, p = .021), marital status(F = 3.375, p = .036), economic status(F = 24.524, p < .001). By means of path analysis, self efficacy affects health status (B = 0.066) and health promotion behavior (B = 0.617), and health status affects health promotion behavior (B = 1.932). These findings provide information that is relevant in interventions of self efficacy and health status to enhance health promotion and quality of life in middle aged adults.
Lee, Youngmi,Kwon, Eun-Young,Choi, Myung-Sook MDPI 2018 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.19 No.10
<P>Isoliquiritigenin (ILG) is a flavonoid constituent of <I>Glycyrrhizae</I> plants. The current study investigated the effects of ILG on diet-induced obesity and metabolic diseases. C57BL/6J mice were fed a normal diet (AIN-76 purified diet), high-fat diet (40 kcal% fat), and high-fat diet +0.02% (<I>w</I>/<I>w</I>) ILG for 16 weeks. Supplementation of ILG resulted in decreased body fat mass and plasma cholesterol level. ILG ameliorated hepatic steatosis by suppressing the expression of hepatic lipogenesis genes and hepatic triglyceride and fatty acid contents, while enhancing β-oxidation in the liver. ILG improved insulin resistance by lowering plasma glucose and insulin levels. This was also demonstrated by the intraperitoneal glucose tolerance test (IPGTT). Additionally, ILG upregulated the expression of insulin signaling-related genes in the liver and muscle. Interestingly, ILG elevated energy expenditure by increasing the expression of thermogenesis genes, which is linked to stimulated mitochondrial biogenesis and uncoupled cellular respiration in brown adipose tissue. ILG also suppressed proinflammatory cytokine levels in the plasma. These results suggest that ILG supplemented at 0.02% in the diet can ameliorate body fat mass, plasma cholesterol, non-alcoholic fatty liver disease, and insulin resistance; these effects were partly mediated by increasing energy expenditure in high-fat fed mice.</P>
Kim, Ji-Eun,Kang, Seung-Hyon,Moon, Youngmi,Chae, Jin-Joo,Lee, Ah Young,Lee, Jae-Ho,Yu, Kyeong-Nam,Jeong, Dae Hong,Choi, Mansoo,Cho, Myung-Haing American Chemical Society 2014 Chemical research in toxicology Vol.27 No.2
<P>Since the discovery of carbon nanotubes (CNTs), scientists have performed extensive studies on nanotubes in the fields of materials science, physics, and electronic engineering. Because multiwalled CNTs (MWCNTs) are not homogeneous materials, and because it is not feasible to test every newly synthesized MWCNT, this study was aimed at investigating the physicochemical properties that primarily determine the cellular toxicity of MWCNTs. This study analyzed the relationship between cell viability and physicochemical characteristics following exposure to eight different MWCNTs. We generated eight different MWCNTs using various synthetic methods and post-treatments. From this analysis, we sought to identify the major physicochemical determinants that could predict the cellular toxicity of MWCNTs, regardless of the synthetic method and post-treatment conditions. Creation of binding sites on the tube walls by breaking C–C bonds played a pivotal role in increasing toxicity and was most clearly demonstrated by a Raman G peak shift and the <I>I</I><SUB>D</SUB>/<I>I</I><SUB>G</SUB> ratio. In addition, several factors were found to be strongly related to cellular toxicity: surface charge in the case of MWCNTs created by the chemical vapor deposition method and surface area and EPR intensity in the case of MWCNTs created by the arc discharge based method. The methods developed in this study could be applied to the prediction of the toxicity of newly synthesized MWCNTs.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/crtoec/2014/crtoec.2014.27.issue-2/tx400397g/production/images/medium/tx-2013-00397g_0011.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/tx400397g'>ACS Electronic Supporting Info</A></P>