남성화를 보이는 여성에서 발견된 난소의 Steroid Cell Tumor 1예

조인호,정대훈,박영미,서영진,손영실,정철회,강영미,정수전,김영남,이경복,성문수,김기태 인제대학교 2006 仁濟醫學 Vol.27 No.-

Steroid cell tumor is a rare ovarian sex cord-stromal tumor which accounts for 0.1% of all ovarian tumors. Until now, only 4 cases have been reported in domestic literatures. Steroid cell tumor often secrets testosterone and presents virilization in adult women or precocious puberty in children. Treatment is often performed by surgical removal, adjuvant chemotherapy and radiation, but completely accepted treatment was not existed. We experienced a case of steroid cell tumor, which was manifested by typical virilization in a 43-year old patient, who was previously performed hysterectomy and unilateral oophorectomy. So, we present with a brief review of the literatures.

고령자 급성 췌장염의 임상적 고찰

백용한,서정훈,송건훈,이진헌,송시영,정재복,강진경,박인서,이수진 大韓消化器病學會 1998 大韓消化器病學會誌 Vol.32 No.3

야생식물 중독의 임상 양상

옥택근,박찬우,조준휘,천승환,이승용,김성은,최기훈,배지훈,서정열,안희철,안무업,조병렬,김용훈,Ok, Taek-Gun,Park,, Chan-Woo,Cho, Jun-Hwi,Cheon, Seung-Whan,Lee, Seung-Young,Kim,, Sung-Eun,Choi, Ki-Hoon,Bae, Ji-Hoon,Seo, Jeong-Yeul,Ahn, Hee-Cheo 대한임상독성학회 2005 대한임상독성학회지 Vol.3 No.2

Purpose: With the recent boom in 'eating healthy', many adults are interested in dieting to prevent future diseases. However only well trained experts can distinguish between what are edible vegetables and herbs from their poisonous look-alikes. In cases where a patient unknowingly ingests a poisonous herb, is caught off guard by the poisonous side effects that occur because of their lack of knowledge of what they have ingested. This paper will focus on the need to educate the public about the risks involved with ingesting wild vegetables and herbs and study the emergency diagnosis and treatment of poisoned patients that enter the emergency room. Method: This study was done in the spring of 2004 (from March to May) in the Kangwon Young-Seo districts of Korea. 15 subjects used in this study, entered the emergency room showing signs of toxic symptoms. Data was collected by examining subject's records. Additional data was collected by collaborating with physicians in the hospital that diagnosed and treated the subjects. Identifying the poisonous vegetable or herb is the first step to proper diagnosis and treatment. Subjects admitted to the emergency room, underwent a battery of tests: laboratory examination, ECG, radiological exam and etc. Results: The demographics of the study encompassed subjects with the average age of $50{\pm}19$ years old. There were 10 men and 5 women. Common symptoms of this study included; gastrointestinal symptoms such as nausea, vomiting, epigastric pain and so on. In the case of Caltha palustris ingestion, additional symptoms were present; bradycardia and hypotension which lasted for a long time. While cases that ingested Scopolia parviflora had little effect on vital signs but manic episodes lasted for about three days. Veratrum patulum ingestion showed signs of bradycardia and hypotension but contrary to Caltha palustris recovery was shorten by treating with dopamine. However, dizziness, headache and paresthesia of the extremities continued for a long time. Finally Sium ninsi ingestion showed visual disturbance, paresthesia of the extremities, dizziness as their initial symptoms. Conclusion: The risks involved with ingesting wild plants without the proper knowledge can lead to serious side effects and steps need to be taken to educate the public. In addition, all emergency physicians need to have a working knowledge of the symptoms and signs associated with ingesting toxic wild plants and need to treat accordingly.

상품 속성의 특성과 자료수집 방법이 컨조인트 모형의 효과에 미치는 영향에 관한 비교연구

서상윤;이훈영;남양호 경희대학교 산업관계연구소 2009 産硏論叢 Vol.34 No.-

컨조인트 분석에 사용되는 다양한 속성들은 이들 속성들이 갖는 특성에 따라 컨조인트 분석결과에 영향을 미칠 수 있다. 컨조인트 분석에 활용되는 개별 속성들은 색상이나 브랜드처럼 크기와 방향이 없는 이산적인 경우와 가격 혹은 무게 등과 같이 단조적인 크기와 방향을 갖는 벡터속성인 경우가 있다. 또한 이들 속성간 관계가 상품의 원산지와 색상처럼 상호 독립적인 경우가 있으며, 상품의 용량과 가격처럼 연관되어 있는 경우도 있다. 본 연구에서는 이렇게 상품 속성의 특성이 컨조인트 모형의 예측정확도에 어떠한 영향을 미치는 가를 비교연구 하였다. 연구결과, 상품의 속성들이 이산적인 속성들로 구성되어 있고 속성간에 서로 독립적인 경우, 속성이 단조적인 크기와 방향의 벡터속성과 서로 연관된 속성을 갖는 모형보다 예측정확도가 더 높게 나타났다. 또한, 트레이드 오프법과 전체프로필법을 이용한 두 자료수집 방법 간 예측정확도 비교에 있어서 상품의 속성들이 서로 독립적인 경우에는 트레이드 오프법을 이용한 자료 수집방법이 전체프로필법을 이용한 자료수집방법 보다 예측정확도 측면에서 더 효과적인 것으로 나타났고, 속성들이 서로 연관되어 있는 경우에는 두 방법간에 유의한 차이가 없는 것으로 나타났다. The performance of conjoint model tends to depend on the characteristics of product attributes as well as the strength of correlation among attributes. If attributes used in the analysis are highly related with each other, the thult of conjoint analysis might not be so reliable neither effective in measuring the utility. The association among the attribute levels within an attribute also negatively influences on the performance of conjoint model. The purpose of this research is to investigate into how the effectiveness of conjoint model varies depending on the relation among attributes as well as on the monotonic variies depenattribute levels within an attribute. This paper also examines which data collecting method is more angropriiee depending on the different association among attributes and attribute levels' characteristics within an attribute. This research finds that both the dependency among attributes and the monotonic variies depenattribute levels influence the accuracyepenebute. ed conjoint model. The model develonto with independent product attributes outperforms that with sibuwhat related product attributes. The better model is ebute. ed whennattribute levels are non-monotonic relirelated ds independent. Also when attributes are independent, the model mas onic vardata collected uthe m vart as well method outperforms that develonto using the data collected by the full profile method.

네모나프라이드의 유효성 및 추체외로 부작용 : Haloperidol 및 Risperidone과의 자연관찰적 개방형 비교연구 A Naturalistic Open Comparative Study with Haloperidol and Risperidone

서영수,김용관,신동환,공보금,이정구,박정환,윤성환,정치영,이상경,김영훈 대한생물치료정신의학회 2001 생물치료정신의학 Vol.7 No.2

Objectives : This open prospective study was performed in order to evaluate the efficacy and extrapyramidal adverse effects of nemonapride in the schizophrenic patients, and was compared wit one of typical antipshchotics. haloperidol and one of atypical antipsychotics, risperidone. Methods : Thirty male and female schizophrenic patients(DSM-Ⅳ) were treated for 12 weeks with haloperidol(n=10), risperidone(n=10) and nemonapride(n=10). The overall efficacy was assessed at baseline, 1st week, 2nd week, 4th week, 8th week, and 12th week by the Positive and Negative Syndrome Scale for Schizophrenia(PANSS). Also the overall safety was assessed in the same time period by the Extrapyramidal Symptom Rating Scale(ESRS). Results : There were no significant differences in PANSS scores(total, positive, negative, and general psycho­pathology subscale) among haloperidol, risperidone, and nemonapride groups, Treatment responders, defined as at least 20% reduction of baseline total PANSS score, were achieved by 8 patients(80%) in haloperidol group, 10 patients(100%) in risperidone group, and 8 patients(80%) in nemonapride group. And there were no significant differences in ESRS total scores among haloperidol, risperidone, and nemonapride group. Inter-group comparison among haloperidol, risperidone and nemonapride group, as assessed by the ESRS, revealed no significant differences in the shifts to the maximum score, 9.4(±9.4), 6.2(±8.4), and 11.3(±8.1) respectively, and also revealed no significant differences in the mean time reaching the maximum score, 4.5(±4.5) week, 7.8(±4.8) week, and 4.6(±4.4) week, respectivily. Conclusion : There wee no significant differences in the efficacy and extrapyramidal adverse effects among haloperidal, rispecridone and nemonapride groups. These results suggest that nemonapride was as efficacious and safe in he treatment of schizophrenia, as well known and widely used antipsychotics, haloperidol and risperidone.

수종의 레진 모노머가 우식 유발성 세균의 활성에 미치는 영향

서영주,국중기,윤정훈,김수관,이난영,이상호 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.2

이전의 연구에서 레진 재료를 포함한 여러 수복재료에서의 유출물이 우식 유발 세균의 성장에 영향을 줄 수 있다는 보고가 있었다. 이번 연구의 목적은 대표적인 우식 유발 세균인 Streptococcus mutans와 Streptococcus sobrinus의 성장에 대하여 레진을 구성하는 모노머들(Bis-GMA, TEGDMA, EGDMA, UDMA, HEMA, Camphoroquinone)이 어떠한 영향을 줄 수 있는지에 대하여 알아보고자 하는 것이다. 결과는 다음과 같다. 1. S. mutans와 S. sorbinus의 성장률은 6가지 레진 모노미 모두에서 0.03 m㏖/L의 농도에 서 유의할 만하게 감소되었다. 2. S. mutans의 성장률은 0.01 m㏖/L 농도의 UDMA의 0.005 m㏖/L, 0.01 m㏖/L 농도의 Camphoroquinone에서 대조군에 비하여 유의할만하게 감소되었다. 3. S. sorbinus의 성장률은 0.01 m㏖/L 농도의 HEMA. UDMA와 0.005 m㏖/L, 0,01 m㏖/L 농도의 Camphoroquinone에서 대조군에 비하여 유의할만하게 감소되었다. 4. S. sorbinus의 성장률은 0.001, 0.01, 0.03 m㏖/L 농도에서 대조군에 비하여 유의할만한 감소를 보였으며 각 실험군들 간에도 통계학적으로 유의할만한 차이를 보였다. 이상의 결과를 종합하면 레진 모노머를 적용한 모든 군에서 적용하지 않은 양성 대조군에 비해 두 세균의 증식률이 감소되었으며, 세균의 성장을 촉진하지 않은 것으로 사료된다. The purpose of this study was to examine the effects of resin composite monomers (Bis-GMA, TEGDMA, EGDMA. UDMA. HEMA, Camphorquinone) on the growth of the two cariogenic bacteria, Streptococcus mutans and Streptococcus sobrinus. We obtained the following results : 1. The growth rate of S. mutans and S. sobrinus was decreased significantly in the group of all composite resin monomer at a concentration of 0.03mmoI/L(P〈0.01). 2. The growth rate of S. mutans in the group of UDMA at a concentration of 0.01 mmol/L and the group of CQ at a concentration of 0.005 mmol/L, 0.01 mmol/L 1%-as decreased significantly compared to the control group(P〈0.01). 3. The growth rate of S. sobrinus in the group of HEMA. UDMA at a concentration of 0.01 mmol/L and the group of CQ at a concentration of 0.005mmol/L. 0.0lmmol/L was decreased significantly compared to the control group(P〈0.01). 4. The growth rate of S. sobrinus in the group of EGDMA at a concentration of 0.001, 0.01. 0.03mmol/L was decreased significantly compared t o the control group (P〈0.01) and were showed to be statistically significant difference between experimental groups(P(0.01).

한국어 자연발화 처리를 위한 개념 기반 분석

서영훈 충북대학교 컴퓨터정보통신 연구소 2001 컴퓨터정보통신연구 Vol.9 No.1

본 논문에서는 한국어 자연발화처리를 위한 개념 기반 분석에 대해 기술한다. 본 논문에서 제안하는 개념 문법은 각 규칙의 성분들 사이에 순서 개념이 없고, 규칙에 기술된 성분 중에서 일부만 발화문에 나타나도 규칙이 적용되며, 규칙에 있는 모든 성분들이 발화문에 연속해서 위치되어 있을 필요가 없다는 점을 특징으로 가진다. 개념 문법을 이용하는 파서는 기본적으로 발화문의 왼쪽부터 오른쪽 방향으로 분석을 진행하는데, 만일 구절의 중심어를 만나면 중심어의 왼쪽에 있는 성분들과만 결합할 수 있다. 중심어가 체언일 경우는 바로 앞에 있는 하나 이상의 관형어 또는 관형절까지를 범위로 하며, 중심어가 용언일 경우는 그 앞에 있는 용언의 바로 다음 어절부터 현재 용언까지를 분석 범위로 한다. 본 논문에서 기술하는 개념 기반 분석은 비문법적인 문장 성분이 많은 자연발화문의 특성과 부분 자유 어순을 가지는 한국어 특성에 적합하도록 설계되어, 자연발화처리에 가장 중요한 요소 중의 하나인 강건한 분석을 한다. This paper describes a concept-based approach for Korean spontaneous speech analysis. Our concept grammar has some characteristics such that the order of elements in right-hand side of a rule is meaningless, a rule can be applied although only parts of elements of a rule exist in utterance, and all elements of a rule need not be contiguously located in utterance. Concept-based parser analyzes an utterance left-to-right basically, but finds needed constituents only to the left of the head if current constituent is a head in grammar. Scope to find constituents for a head is one or more modifiers before the head in case of nominal head, and from a word immediate after a preceding verb to current verb in case of verbal head. Our concept-based approach is robust and appropriate for spontaneous speech utterance which has lots of ungrammatical constituents and for partially-free word order Korean characteristics. Keywords: spontaneous speech, spoken language, concept grammar, concept-based analysis, Korean analysis

악성종양과 감별이 어려웠던 악안면 영역의 감염질환에 대한 치험례

서재훈,김영균,여환호 大韓顎顔面成形再建外科學會 1995 Maxillofacial Plastic Reconstructive Surgery Vol.17 No.3

It is very difficult to differentiate the malignant tumor from the maxillofacial infections that have unclear cause, severe indurated swelling, pain and nonresponsiveness to antibioitic treatment and incision and drainage. Incisional biopsy, CT, and MRI examination may not distinguish between infection and a malignant tumors. And then, the clinicians can make a mistake that they perform a unnecessary radical surgery because of inaccurate diagnosis. We present three case reports of maxillofacial infectious disease with diagnosis process, treatment and differential diagnosis. The infectious disease were not resolved with antibiotic and surgical drainage. The progression of clinical sign and radiographic, indings of these disease were masqueraded as malignant tumors.

급성 운동 신경 축삭성 신경병증과 동반된 기관지내 이물 1예

조영신,전웅,이호성,최재성,나주옥,서기현,김용훈 순천향의학연구소 2008 Journal of Soonchunhyang Medical Science Vol.14 No.1

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개념 및 구문 기반의 한국어 자연발화 번역 시스템

서영훈 충북대학교 컴퓨터 정보통신 연구소 1999 컴퓨터정보통신연구 Vol.7 No.1

본 논문에서는 강건한 한국어 자연발화 분석기와 한-영 자연발화 번역시스템에 대해 기술한다. 한국어 분석기는 기본적으로 개념 기반의 분석 기법을 이용하되, 구문 정보도 이용한다. 본 논문에서는 중요하지 않은 문장 성분을 무시하고 분석할 수 있는 핵심개념 기반 파싱 기법을 제안한다. 이 파싱 기법은 비문법적인 요소가 많은 자연발화를, 중요 정보의 손실 없이 거의 모두 분석할 수 있도록 함으로써 시스템의 강건성을 매우 향상시킨다. 또한 성분 사이에 순서가 없고, 오직 지배 관계만을 나타내는 문법을 이용하기 때문에, 문법이 매우 단순해지고 따라서 관리하기 쉬어진다는 점이 장점이다. 이 분석기를 이용하는 한-영 자연발화 번역 시스템은 실험결과 95% 이상의 높은 번역 성공률을 보였다. This paper describes a robust Korean analyzer and a Korean-English translation system for spontaneous speech. Our analyzer is basically concept-based system, but it also uses syntactic information. We propose an parsing mechanism based only on core concepts, in that constituents in utterance which can be considered not core concept might be ignored without any significant loss of information. Therefore, it greatly enhances system robustness. Grammar simplicity is another characteristic of our system. Each rule defines only immediate dominance relation, in that the order of each element is meaningless at all. Korean-English spontaneous speech translation system is developed, and it is verified from experiments that average correctness rate of parsing and translation of our system is 95% or over.