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Interface Shear Strength at Joints of Ultra‑High Performance Concrete Structures
Young?Jin Kim,Won?Jong Chin,Se?Jin Jeon 한국콘크리트학회 2018 International Journal of Concrete Structures and M Vol.12 No.6
When ultra-high performance concrete (UHPC) is fabricated as precast members such as in a UHPC segmental bridge, the joint design between the precast members can significantly affect the overall integrity and safety of the structure. Therefore, the structural behavior of the UHPC joint was experimentally investigated in this study with test variables including joint type, number and height of shear keys, type of filler, curing temperature, and lateral compressive stress. The UHPC considered in this study is the K-UHPC developed in Korea with a specified compressive strength as high as 180 MPa and high flowability. The joint shear strengths affected by the test variables were investigated in detail. The test results were also compared with two representative predictive equations for interface shear strength to determine an appropriate equation for the joint design of UHPC. These equations did not match well with the test data because they were originally proposed for normal strength concrete. However, the JSCE equation could be improved by modifying a coefficient to show good agreement with the test especially in the case of the dry joint with epoxy application.
김웅철,이원철,손영석,오세윤,김부섭,유진호,김지환 한국보건의료인국가시험원 2005 보건의료교육평가 Vol.2 No.1
This study prepared a basic framework for the development and improvement of Korean Dental Technicians' Licensing Examination, based on actual test questions. A peer review was conducted to ensure relevance to current practices in dental technology. For the statistical analysis, 1000 dental laboratory technicians were selected; specialists in dental laboratory technology (laboratory owners, educators, etc.) were involved in creating valid and reliable questions. Results indicated that examination subjects should be divided into three categories: basic dental laboratory theory, dental laboratory specialties, and a practical examination. To ensure relevance to current practice, there should be less emphasis on basic dental laboratory theory, including health-related laws, and more emphasis on dental laboratory specialties. Introduction to dental anatomy should be separated from oral anatomy and tooth morphology; and fixed prosthodontics should be separated from crown and bridge technology and dental ceramics technology. Removable orthodontic appliance technology should be renamed 'orthodontic laboratory technology'. There should be less questions related to health related law, oral anatomy, dental hygiene, dental materials science and inlay, while the distribution ratio of questions related to tooth morphology should be maintained. There should be a decrease in the distribution ratio of questions related to crown and bridge technology, dental ceramics technology, complete dentures and removable partial dentures technology, and orthodontic laboratory technology. In the practical examination, the current multiple choice test should be replaced with tooth carving using wax or plaster. In dental laboratory specialties, subjects related to contemporary dental laboratory technology should be included in the test items.
제4형 가족성 고중성지방혈증 임산부에서 발생한 급성 췌장염 1례
박관응,윤채중,김영학,진영기,윤성호,권용은,김태원,박찬국,김만우 朝鮮大學校 附設 醫學硏究所 1997 The Medical Journal of Chosun University Vol.22 No.2
Plasma levels of cholesterol (TC) and triglyceride(TG) physiologically increase during pregnancy. The lipid increment is 23-53% above the pregravidic level for TC and 2- to 3-fold of the prepregnancy level for TG. If the TC and TG are higher than normal values in pregnancy, the patient must be carefully monitored. Acute pancreatitis is the main consequence of hyperlipidemia and occurs either during pregnancy, in the third trimester, or in the puerperium. Mortality is high both for the mother (21%) and the fetus (20%). We report a case of 28 year-old pregnant woman at 29 weeks gestation with hypercholesterolemia (TC = 357 ㎎/dl) and severe hypertriglyceridemia (TG = 1300 ㎎/dl). The patient was admitted to the hospital because of severe epigastric pain, nausea and vomiting. Total serum cholesterol was increased and trigyleride was markedly increased. The electroporesis pattern of serum lipoprotein showed increase in pre-beta lipoprotein fraction, suggesting IV hypertriglyceridemia pattern. According to a review of the literature, the incidence of pancreatitis during pregnancy is 1 in 1000 to 3000 pregnancies. Severe hypertriglyceridemia in pregnancy should be treated with a careful restriction of calories and fat: for preventing acute pancreatitis, hospitalization for intravenous fluid therapy and plasma exchange must be required.
Studies on Medium-Term Carcinogenicity Tests Using Genetically Engineered Mice
Young-Suk Won,Hyo-Jung Kwon,Yang-Kyu Choi,Won-Kee Yoon,Ki-Hoan Nam,Oc-Sung Moon,Hyoung-Chin Kim(김형진) 한국실험동물학회 2008 한국실험동물학회 학술발표대회 논문집 Vol.2008 No.-
A long-term carcinogenicity study is required to assess the safety of new drug candidates. This classical toxicological method has been using rats and mice as animal systems. The International Conference on Harmonization of Technical Requirements of Pharmaceuticals for Human Use (ICH) have recommended a long-term rodent carcinogenicity test system using rat and a supplementary mouse test system such as an initiation-promotion model, a transgenic model or a neonatal model. This study was carried out to develop a new liver carcinogenicity model using HBx tg mice and disease model mice. The incidence of liver tumor was increased in treated group at 16, 20 or 26 weeks after carcinogen treatment. It was statistically significant compared with the control animals. We could suggest the possibilities of HBx mice and other disease model as a new carcinogenesis screening model system, and if we have more data about reference chemicals for these animals, it will be recommended as alternative test for carcinogenicity risk assessment and used for a rapid evaluation of hepatocarcinogenicity of several chemical.