18–30세 사이에 발생하는 뇌경색의 특징, 다기관 레지스트리 연구

장윤경,송태진,김용재,허지회,이경열,김영은,장민욱,조수진,강석윤 이화여자대학교 의과학연구소 2017 EMJ (Ewha medical journal) Vol.40 No.3

Objectives: Although there have been several reports that described characteristics for young age stroke, information regarding very young age (18–30 years old) has been limited. We aimed to analyze demographic factors, stroke subtype, and 3-month outcome in acute ischemic stroke patient who have relatively very young age in multicenter stroke registry. Methods: We evaluated all 122 (7.1%) consecutive acute ischemic stroke (within 7 days after symptom onset) patients aged 18 to 30 from 17,144 patients who registered in multicenter prospective stroke registry, 1997 to 2012. Etiology was classified by Trial of Org 10172 in Acute Stroke Treatment criteria. Stroke severity was defined as National Institutes of Health Stroke Scale (NIHSS) and stroke outcome was defined by modified Rankin scale (mRS) at 3 months after index stroke. Results: The mean age of all included patients was 25.1±3.7 years and 76 patients (62.2%) were male. The median NIHSS at admission was 4. Considering stroke subtype, 37 patients (30.3%) had stroke of other determined etiology (SOD), 37 (30.3%) had undetermined negative evaluation (UN) and 31 (25.4%) had cardioembolism (CE) were frequently noted. After adjusting age, sex and variables which had P<0.1 in univariable analysis (NIHSS and stroke subtype), CE stroke subtype (odds ratio, 4.68; 95% confidence interval, 1.42–15.48; P=0.011) were significantly associated with poor functional outcome (mRS≥3). Conclusion: In very young age ischemic stroke patients, SOD and UN stroke subtype were most common and CE stroke subtype was independently associated with poor discharge outcome.

수술로 호전되지 않은 췌장 농양을 내시경 치료로 완치한 1 예

서희영;전태주;김선영;강미선;허란;박지영;서동대;오태훈 인제대학교 백병원 2011 仁濟醫學 Vol.32 No.-

Necrotizing pancreatitis develops in about 10-20% of patients with acute pancreatitis, and pancreatic abscesses develop in 3% of them. The mortality of pancreatic abscess has been reported up to 40% in one study. Recently, there are several reports that show good results with n on-surgical therapy, such as percutaneous drainage and endoscopic drainage, but if the non-surgical drainage fails, surgical therapy are recommended. However, there is no definite therapeutic method which is suggested yet so far after the failure of the surgical drainage. So we report the case in which we experienced successful treatment of pancreatic abscess by endoscopic removal of necrotic tissue through the gastrocystostomy, after the failure of the surgical debridement and internal drainage through gastrocystostomy.

위치 제어계에서 신경망에 의한 2 자유도 PID 제어계의 구성

허진영,하홍곤,고태언 동의대학교 산업기술개발연구소 2000 産業技術硏究誌 Vol.14 No.-

Many industrial control system often use PID, I-PD in sort of the conventional control system method. But it is difficult to control a satisfactory response in variable load and changing parameter, can not have the both purpose of setpoint tracking and disturbance rejection at the same time. Therefore we propose 2-DOF(Degree of Freedom) PID controller ebust for tracking function in the target value point as well as removal disturbance. In this paper construct to 2-DOF PID control system in the position control system at D.C servo motor. first construct 2-DOF PID controller by a neural network. 2-DOF parameter (α, β, γ, η ) is tuned by the back-propagation algorithm of neural network. we consider the 2-DOF control system in the position control system and verify availableness of proposal method through the result of computer simulation.

모성으로 구축하는 여성 택견의 새로운 패러다임에 관한 탐색

김영학,장경태,김태일,허채봉 龍仁大學校 武道硏究所 2011 武道硏究所誌 Vol.22 No.1

여성택견연맹은 택견의 최고지도자가 택견미래를 위한 포석으로 창설을 주도한 것이다. 그런 만큼 연맹의 기능과 역할에 거는 택견전체의 기대가 큰 것을 알 수 있다. 그럼에도 연맹은 그 기대에 부응하지 못하고 조직 자체의 존폐가 위기에 몰렸던 것도 사실이다. 이제 새로 출범하는 제2기 연맹은 회장을 중심으로 외견상으로 볼 때 탄탄한 진용임이 분명하다. 집행부의 임원 한 사람 한 사람의 면면을 보면 충분히 수긍이 간다. 다시 말해 인적자원은 충분하다는 뜻이다. 문제는 이 인력을 얼마나 활용하느냐 하는 것이라고 생각된다. 지난 날 잘 한 것을 계승하여 더욱 활성화하고 부족했던 부분을 보완하고 개선하면 될 것이다. 앞서 살펴본 바와 같이 모든 문제의 시작과 결과는 여성택견인들의 참여의식의 여부에 달려 있다고 판단된다. 우리 연맹이 정체된 것도 따지고 보면 바로 우리 각자의 이기주의적․편의주의적 의식에 기인하는 것이라고 생각한다. 공동체적 가치를 지향할 때 인간은 인간다워진다는 것이 보편적 진리이다. 이를 모를 사람은 없을 것이다 그런데 알면서도 이를 실행하지 못하는 것이 어려운 문제인 것이다. 택견 내부의 공동체적 가치구현을 우리 여성연맹 구성원들이 지닌 모성적 이타주의로 이끌어 나간다면 여성연맹의 기능은 활성화될 것이다.

정상인의 입각기에서 발바닥압력측정시 압력중심점의 위치

허재균,박시복,이상건,이강목,김영호,양길태,장윤희 大韓再活醫學會 1998 Annals of Rehabilitation Medicine Vol.22 No.2

방사선 조사가 배양된 조골세포의 apoptosis와 세포주기의 변화 및 석회화 결절 형성에 미치는 영향에 관한 연구

이영미,최항문,허민석,이삼선,최순철,박태원 대한구강악안면방사선학회 2000 Imaging Science in Dentistry Vol.30 No.3

Purpose : The study was aimed to detect the induction of apoptosis, cell cycle arrest and calcified nodule formation after irradiation on primarily cultured osteoblasts. Materials and Methods : Using rat calvarial osteoblasts, the effects of irradiation on apoptosis, cell cycle arrest, and calcified nodule formation were studied. The single irradiation of 10 and 20 Gy was done with 5.38 Gy/min dose rate using the 137Cs cell irradiator at 4th and 14th day of culture. Apoptosis induction and cell cycle arrest were assayed by the flowcytomtry at 1,2,3, and 4 days after irradiation. The formation of calcified nodules was observed by alizarin red staining at 1,3,10,14 days after irradiation at 4th day of culture, and at 1,4,5 days after irradiation at 14th day of culture. Results : Apoptosis was not induced by 10 or 20 Gy independent of irradiation and culture period. Irradiation did not induced Gl arrest in post-irradiated ostedblasts. After irradiation at 4th-day of culture, G2 arrest was induced but it was not statistically significant after irradiation at 14th-day of culture. In the case of irradiated cells at 4th day of culture, calcified nodules were not formed and at 14th-day of culture after irradiation, calcified nodule formation did not affected. Conclusion : Taken together, these results suggest that Irradiation at the dose of 10-20 Gy would not affect apoptosis induction of osteoblasts. Cell cycle and calcified nodule formation were influenced by the level of differentiation of osteblasts. (Korean J Oral Maxillofac Radiol 2000; 30: 189-198)

컴퓨터주제 인성교육프로젝트가 유아의 컴퓨터 활용에 대한 부모의 태도에 미치는 영향

박영태,허해옥 동아대학교 교육대학원 2002 동아교육논총 Vol.28 No.-

The purpose of this study was to analyze parent's aptitude change for preschooler's using computer by Computer Topic Project for Personality Development. The subject were 115 preschoolers sampled from one of kindergarten in Pusan. They divided into two groups, computer topic project for personality development group, computer topic project group. The following conclusion were derived from results of this study. It's desirable to teach how to use computer by computer topic project for personality development to preschooler. Computer topic project for personality development can make preschooler to solve computer using conflicts with others. So computer topic project for personality development let prescholer's parent's aptitude of preschooler's using computer change positively.

삼보감(Citrus sulcata Hort. et Takahashi) 유실물체에서 유도된 캘러스의 체세포배 형성과 식물체 재분화

박수영,허인옥,부지현,한태완,송관필 濟州大學校 基礎科學硏究所 1998 基礎科學硏究 Vol.11 No.1

삼보감에 있어서 기내 체세표배 발생을 통한 다량증식을 도모하기 위해서 캘러스 증식 및 체세포배 발생, 배로부터 식물체 재분화에 미치는 배지 및 Polyamine, 생장조절제의 효과를 구명하기 위해 실시하였다. 삼보감 과실에서 채집된 종자를 호르몬이 첨가되지 않은 MS배지에서 무균발아시켰다. 발아된 유식물체의 줄기에서 캘러스를 유도하기 위해 NAA와 BA가 첨가된 MT 배지에서 배양하였고 5mg/L 2,4-D와 1mg/L BA가 첨가된 배지에서 계대배양하였다. 캘러스를 증식시키기 위한 배양조건 설정으로 배지별과 Polyamine(Spermidine, Spermine, Putrecine) 농도별(0 - 1mM)에 따른 생장량을 좌하였다.배지별에 따른 생장율은 MT배지에서 0.968g(fr wt)으로 가장 높았고, Polyamine의 영향은 0.01 mM Putrecine 처리구에서 0.78g으로 가장 높게 나왔다. 배발생 캘러스는 0.1mg/L NAA와 0.5mg/L BA가 첨가된 MT배지에서 유도하였으며 유되된 체세포배를 식물체로 재분화시키기 위해서 0.1mg/L NAA와 1mg /L BA가 첨가 된 MT배지에서 배양하였다. This study was performed to investigate the culture condition induction of somatic embryo and plant regeneration in callus induced from Citrus sulcata leaf and stem as a basic research for breeding of new plant. The seeds of Sambokam were germinated in hormone free MS medium under sterile condition. Callus induced form stem and leaf geminated young plant in MT supplemented with NAA plus BA and subcultured in MT supplemented with 5 ㎎/ L 2,4-D and 1 ㎎/L BA. As a investigation of culture condition for callus proliferation, growth rate of callus were investigated in various medium and polyamine concentrations. The effect of medium was most effective in MT medium as 0.968g and polyamine was most effective of in 0.01mM putrecine among various concentration. Formation of embryogenic callus induced from MT medium containing 0.1 ㎎/L and 0.5 ㎎/L BA. The geminated embryos developed to complete plantlet when cultured on MT medium supplemented with 0.1 ㎎/L NAA and 1㎎/L BA.

토양중 게르마늄 농도에 따른 벼의 생육 특성 및 게르마늄 흡수

이성태,이영한,최용조,이상대,이춘희,허종수 한국환경농학회 2005 한국환경농학회지 Vol.24 No.1

게르마늄의 약리효능이 알려짐에 따라 게르마늄이 깅화된 기능성 농산물의 요구도가 높아지는 추세이다. 본 연구는 게르마늄의 농업적 이용에 대한 기초 사료를 제공하고자 실시하였으며, 벼의 생육 및 게르마늄 흡수에 미치는 게르마늄처리 효과는 다음과 같다. 게르마늄을 0, 2.5, 5.0, 7.5 및 10.0 mg/kg으로 처리할 토양을 와그너포트에 넣어 벼를 재배힌 결과, 게르마늄 처리농도가 증가할수록 게르마늄 독성의 증가로 초장, 수장, 수수 및 수량이 급격히 감소하였으며 게르마늄 2.5 mg/kg 이상에서는 게르마늄 독성이 발생하였다. 게르마늄 처리농도가 증가할수록 벼의 게르마늄 흡수랑은 증가하였으나 벼의 게르마늄 이용율은 게르마늄 2.5, 5.0, 7.5 mg/kg 처리에서 각각 20.7, 12.5 및 7.5%로서 게르마늄 처리농도가 증가할수록 감소하였다. 벼의 부위별 게르마늄 함량은 볏짚>왕겨>현미 순으로 높았다. 게르마늄 2.5 mg/kg 처리시 볏짚, 왕겨 및 현미의 게르마늄 함량은 각각 103.4, 30.2 및 3.02 mg/kg 이었고, 볏짚과 왕겨에서는 게르마늄 무처리에서도 각각 2.9 및 3.9 mg/kg을 함유하고 있었다. 쌀의 아미노산 함량을 분석한 결과 게르마늄 처리농도가 증가할수록 Asx., Thr., Ser. 등 대부분 종류의 아미노산 함량이 증가하였으며, 그 결과 현미중 질소흡수량도 증가하였다. In order to obtain the basic information for agricultural utilization of Germanium(Ge), the growth characteristics and Ge absorption of rice plant were investigated with different Ge concentration in soil. Ge concentrations were treated with 0, 2.5, 5.0 7.5 and 10.0 mg/kg in pot(1/5,000a), respectively. As higher the Ge concentration in soil, the Ge absorption amount in straw, husk and brown rice were increased. But the yields were decreased with the increase of Ge phytotoxicity. When rice plant was grown more than 2.5 mg/kg Ge(as GeO₂) in the soil, growth was inhibited by germanium phytotoxicity and necrosis spots were observed in the rice leaf blades. Therefore the optimum concentration of Ge was less than 2.5 mg/kg in rice plant. When rice plant was cultivated on soil supplemented with 2.5 mg/kg Ge, Ge content in straw, husk and brown rice was 103.4, 30.2 and 3.02 mg/kg, respectively. The Ge content in plant was high in the order of straw > husk > brown rice. Most of the amino acids in rice were increased with the increase of Ge treatment, besides, total amino acid contents also increased.

제주 차귀도 연안해역 미생물 분포 및 이화학적 특성

문영건,김만철,이준백,송춘복,여인규,김종만,박근태,손홍주,최우봉,허문수 한국환경과학회 2006 한국환경과학회지 Vol.15 No.3