한국인 인슐린 비의존형 당뇨병 및 이차성 당뇨병 환자에서 글루코키나제 유전자 변이

남재현(Jae Hyun Nam),이현철(Hyun Chul Lee),김연의(Youn Euy Kim),권석호(Suk Ho Kwon),윤용석(Yong Suk Yoon),박석원(Suk Won Park),원영준(Young Jun Won),차봉수(Bong Su Cha),송영득(Young Duk Song),이은직(Eun Jig Lee),임승길(Sung Kil Lim) 대한내과학회 1998 대한내과학회지 Vol.54 No.6

N/A Objectives: Mutations in the glucokinase (GCK) gene are considered a possible cause of maturity-onset diabetes of the young. The purpose of this study was to evaluate the contribution of this gene to the development of non insulin dependent diabetes mellitus (NIDDM), gestational diabetes mellitus (GDM) and post-renal transplantation diabetes mellitus (PTDM). Method: Identification of GCK mutation was attempted on 39 NIDDM patients, 2 GDM patients and 58 selected renal allograft recipients with PTDM and 45 normal controls. The exons in the GCK gene were examined by polymerase chain reaction (PCR), followed by analysis of single-stranded DNA conformational polymorphism (SSCP). The abnormal bands were also confirmed by DNA sequencing analysis. The exons of affected family members were also investigated for mutations of the GCK gene. Results: Two of the 58 PTDM patients (3.4%) were found to have CKK mutations. One had the mutation on exon 5 and the other on intron 7. One control subject had the mutation on intmn 9. The mutation of exon 5 was identified as a substitution of CCT (proline) for CTT (leucine) at codon 164, which has not ever reported before. The family members of the PFDM patient with mutation of exon 5 were analyzed by PCR followed by SSCP, and two of them revealed the same mutation. The abnormal band on the SSCP analysis of exon 7 was identified as the insertion of base C/T at the 39th nucleotide in intron 7. Two family members of this patients also had same band on SSCP. The one mutation of 45 normal controls was CT located at the 8th nucleotide in intron 9, which was a common polymorphism. Conclusion: We found GCK mutations in subjects with PTDM and we speculate that these mutations may be one of the contributing cause of PTDM.

지능형 정속주행 제어시스템 개발

임영도,설재훈,한창훈,김승철,박종오,이준탁,방석원 東亞大學校 附設 情報通信硏究所 1998 情報通信硏究所論文誌 Vol.6 No.1

This paper describes an intelligent cruise control system for automobile. With the remarkable numericalincrease of automobiles on the roal, the optimized traffic flow control using the cruise control is one of the very important traffic problems to overcome the limitation of an existing road capacity. Based onthis idea that minimize the fuel cost and teh air pollution, and accept a driver's needs for driving, we have developed an intelligent cruise control system for vehicle. This proposed intelligent fuzzy cruise controller was successfully implemented using the fuzzy algorithm, the i80c196 μ-controller board and the throttle valve actuator. The field test results on an linear road was introduced.

K-WISC-Ⅲ를 이용한 ADHD 아동의 인지적 특성에 관한 연구

임목옥,오상우,백영석 圓光大學校 醫科學硏究所 2004 圓光醫科學 Vol.19 No.2

증후성 Rathke열 낭종 : Transseptal transsphenoidal approach via columella flap

임동명,전세영,장석정 조선대학교 부설 의학연구소 1999 The Medical Journal of Chosun University Vol.24 No.1

Rathke's cysts are sellar and suprasellar lesions that are found incidentally in about 13-22% of autopsy cases. Clinical symptoms of Rathke's cyst are usually the result of local mass effect. The most common symptom is headache, and other symptoms which arise are pituitary dysfunction, compression of the visual apparatus and the pituitary stalk. It is very important to distinguish Rathke's cyst from craniopharyngiomas(more common cystic tumor) because of the operative management. We reported a rare case of symptomatic Rathke's cleft cyst. This cyst was removed by transseptal transsphenoidal approach via columella flap. Postop result was satisfactory without serious complications.

Pulsed field gel electrophoresis(PFGE)를 이용한 Yersinia entirocolitica의 특성조사

임순영,윤석권 동덕여자대학교 생활과학연구소 2006 생활과학연구 Vol.11 No.-

Pulsed field gel electrophoresis(PFGE) was conducted compare the Not I digested genomic profile of one hundred Yersinia entirocolitica. This method was very efficient for subtyping pathogenic and non-pathogenic isolates of Yersinia entirocolitica. Generally, pulsotype was more closer to serotype than biotype. But pulsotype of 3/O:5 was more related to biotype than serotype. For epidemiological purpose, the comparison of relationship among biotype. serotype, RAPD(random amplitication of polymorphic DNA) and pulsotype of PFGE should be studied as powerful tools.

교육방송 TV 프로그램 시청자 요구분석

임재석,이영림 한국교육정보방송학회 2001 교육정보미디어연구 Vol.7 No.1

본 연구에서는 초·중·고등학생을 대상으로 텔레비전 시청형태와 기존 교육방송 프로그램에 대한 인지도 및 프로그램 내용에 대한 요구에 대해서 알아보았다. 이에 따라 수용자의 다양한 요구를 객관적으로 분석하여 현재 방송되는 프로그램에 대한 수용자의 의견을 향후 교육방송 프로그램 편성 및 제작에 대한 기초 자료를 제공하고자 하였다. 조사 내용은 학생들의 방송 프로그램 시청 습관, 교육 방송 프로그램 편성 요구, 교육 방송 프로그램 내용 요구, 교사들의 TV 활용 수업 의견 등 4가지 분야로 나누어 분석하였다. 분석 결과를 보면, 첫째, 초등학교 교과 프로그램은 자연과 영어 교과, 중학교 교과 프로그램은 사회와 영어 교과, 고등학교 교과 프로그램은 수리 탐구 영역(고 3 수학교과)과 외국어 영역(고3 영어 교과)을 증가해야 한다는 요구가 많았다. 둘째, 위성 TV 방송 출현으로 프로그램 방영 시간은 늘어났으나 시청 대상자의 방송 시청 시간이 증가한 것은 아니라는 점이다. 이유중의 하나는 프로그램을 흥미롭게 편성해 달라는 것이다. 다만 컴퓨터 정보 프로그램과 청소년 참여 프로그램을 중심으로는 시청율이 증가하고 있는 것으로 나타났다. 셋째, 시청자들이 교육방송 프로그램을 제대로 이해하고 활용할 수 있도록 적극적으로 홍보할 수 있는 방안이 강구되어야 할 것이다. The opinions of school students and teachers are very important in educational broadcasting program. They are the main users in educational broadcasting program. The purpose of this thesis is to suggest a new direction towards educational broadcasting programs, especially focussed on the need of school students and teachers. In order to conduct this research, the researcher analyzed literatures related to educational broadcasting system, program classification, the need , and the need analysis. To find the opinions of students and teachers, a survey was conducted to 6 elementary schools, 6 middle schools and 6 high schools in the Chung-Nam province, and the researcher especially collected and arranged the opinions of teachers who are working in the school related to this survey. The researcher was able to draw the following suggestions from the result of this study; 1. The programs should not be concentrated in educational programs, but should be broadened to the programs related to the things such as computer information and job. 2. The programs should be made with the format that students like, for example, animations or dramas. 3. A lot of marketing campaigns for educational broadcasting programs should be needed. 4. The study about the educational course programs should be continued to meet the needs of student audience.

아시아 경기대회의 서구화와 그 반성

임영무,안희숙 한국체육사학회 2001 체육사학회지 Vol.7 No.-

We together had a chance to think over the subject of Asian Games. It may looks issuance of regionalism or nationalism against the current on of globalization however, in order to find the ways for the further development of the spirit of Asian Games, it is believed that it's time to open the discussion on it. We also did put efforts to search the next deploying goals of the Asian Games, while reviewing both positive and negative aspects of the Games through the chronological investigation of Asian Games history, and researching the situational aspects of pre-modern and modern Asian sports. Thinking over the two aspects, positive and negative viewpoints, of the general effects of the Asian Games to Asian sports, the 4 positive effects of Asian Games may be pointed out ; ①that Asian Games affected to solidify the generalization of the culture of sports attributed to bringing the perception change about sports in Asian people, ② that it also contributed to spreading the Asia-origin sports to the world ③ that it established the infrastructure of sports in Asia through changing the game holding place among Asian countries, and ④ that it provided the good chances to exchange the national cultures among Asian countries. On the other hand the negative aspects may be mentioned ; ①that the loss of Asian traditional sports culture could be ascribed to the fact that the western sports has been the mainstream in Asian Games ② that the magnitude expansion strategy of the Games limited the number of Game hosting cities, so that only a few cities could hold the Game thus far, ③ that the original spirit of Asian Games has been impaired by making political use of Asian Games like the case of Olympic Games, and ④ that the deployment of diversity of world sports cultures into Asia was not enough Directions that Asian Games in 21st century is moving forward can be ; ① to study the Games operation centered on Asian traditional sports, ② to put efforts on magnitude optimization of the Game in size ③ seek the ways exclude the various non-sports ideologies in order for Asian Games to be the untained place of Asian harmony and advancement. To act Asian Games as a role to promote the Asian peace and goodwill among the Asian countries, the hosting country of the Games needs to establish the (hosting) policies and procedures toward of reconciling the different opinions among the member countries and enhancing the friendships, and to implement it. All participants to the international Games are requested to contribute to both the goodwill of Asian countries and world peace by the sportsmanship, the reciprocal cooperative competition.

Random Amplification of Polymorphic DNA(RAPD)를 이용한 Yersinia enterocolitica의 PCR Fingerprinting비교

임순영,윤석권 동덕여자대학교 생활과학연구소 2006 생활과학연구 Vol.11 No.-

The lamer single primer was used to generate random amplification of polymorphic DNA(RAPD) profiles by polymerase chain reaction(PCR) for 100 strains of Y. enterocolitica from various sources. The RAPD pattern within same serotype was devided into different subtypes and also RAPD pattern of different serotypes showed same RAPD type. Regardless of serotype for Y. enterocolitica, DNA fingerprinting bands of non-pathogenic strains were a few in number and small in size but those of pathogenic were reversed. Every serotype showed unique RAPD pattern. therefore it is possible to discriminate within Y. enterocolitica strains. Showing some strains no band or a few, RAPD is effective method to subtype the strains. If RAPD was utilized with serotyping and biotyping, it should be powerful tool to devide Y. enterocolitica strains for epidem iological purpose.

穀類 및 豆類의 腐敗程度와 化學的 成分間의 相互關係

林順英,尹錫權 同德女子大學校 1996 同大論叢 Vol.26 No.1

Various cereals and legumes as well as rice have been used as food in this country. The growth rate of microorganism in those food was different by different food sources. This difference was supposed to be different nutrient contents that are composed of food. Therefore, four kind of cereals (rice, barley, millet and sorghum) and legumes (soybean, small red bean, mungbean and cowpea) were heated at 121℃ for 20 minutes and then the growth rate of microorganisms was measured at four hour intervals unitl 32 hours after heating. Also changes in pH, free sugar, ammonium nitrogen, free amino acid and minerals of cereals and legumes were investigated also relationship with growth rate of microorganisms were estimated. The growth rate of microorganism in legumes was faster than cereals. Exceptionally number of microorganism in sorghum was alsmost same as those in legumes. The pH of barley was lowest compared with other cereals and legumes. Free sugars contents in legumes right after steaming were much higher than those of cereals, and after 12 hours, those in all samples was increased however, after 24 hours free sugars were decreased. High correlation between number of microorganism cells and free sugar were noticed that the content of free sugar affected the growth rate of microorganisms. The early ammonium content in sample supposed to be affected on early growth of microorganism because the ammonium content steaming showed a high significant correlation with the number of micrrorganisms. Free sugar content of legumes higher than cereals. Small red bean was the highest while rice was the lowest. Rice, soybean and mungbean after 24 hour showed a little change during incubation while millet was decreased and the others were increased. Total free amino acid content in testing materials showed high correlation with the number of microorganisms at 4, 12 and 16 hours after incubation. In all samples, the contents of potassium and phosphorous were higher than other minerals. All mineral contents of legumes were higher than cereals. Relationship between number of microorganisms at 4, 12 and 16 hours after steaming and total mineral contents in samples showed significant linear correlation.

한국상장기업의 所有構造와 資本調達政策에 관한 연구

임석필,송영열 단국대학교 산업연구소 1997 산업연구 Vol.20 No.-