乾癬患者 臨床報告

吳恩英,朴惠宣,池鮮渶,具德謨 동의대학교 한의학연구소 2001 동의ㆍ경산 한의학 학술대회 Vol.5 No.-

A Reports were done on proriasis which were treated by medications of Sasang Constitution and Constitution-Acupunture in Dept. surgery, opthalmology &tolaryngology, college of Oriental Medicine, Kyungsan University, Pohang, Korea, from May 30. 2000 to JUN 30 2001. we gave score and checked involvement, plaque, erythematous popules, invasiveness according to psoriasis area and severity index. The results were as follows: 1. Sasang Constitution classification was Soyanggin 14(93.33%), Taeumgin 1(6.67%) in the 15 cases. Hyungbangsabaeksan is used in 9 cases(60%), Yanggeuksanhoatang is used in 3 cases(13.11%), Geopungchunggisan is used in 3 cases(20%), Hyungbangdojucksan is used in 1 case(6.57%). 2. In the 9 cases, we checked for over 4 weeks, clinical severity of involvement, plaque, total score(psoriasis area and severity index) was siginificantly decreased(p<05). clinical severity of erythematous popules, itching was decreased but lt is not siginificant(p>05). 3. The mean duration of treatmemt was 73.3 days, result of Excellent or Good improvement was showed on over 120 days. These resilts indicate that Sasang Constitution and Constitution-Acupuntuer treatment is effetive on psoriasis and the more study is needed.

포켓 가공을 위한 NC 공구경로의 프로그램 개발

오선,권영웅 한국공작기계학회 2003 한국생산제조학회지 Vol.12 No.3

Pocket machining is metal removal operation commonly used for creating depressions in machined parts. Numerically controlled milling is the primary means for machining complex die surface. These complex surfaces are generated by a milling cutter which removes material as it traces out pre-specified tool paths. To machine a component on a CNC machine, part programs which define the cutting tool path are needed. This tool path is usually planned from CAD, and converted to a CAM machine input format. In this paper I proposed a new method for generating NC tool paths. This method generates automatically NC tool paths with dynamic elimination of machining errors in 2½ arbitrary shaped pockets. This paper generates a spiral-like tool path by dynamically computing optimal pockets of the pocket boundary contour based on the type and size of the milling cutter, the geometry of the pocket contour and surface finish tolerance requirements. This part programming system is PC based and simultaneously generates a G-code file.

흰쥐 심장혈관계통에서 3β-hydroxysteroid dehydrogenase/△⁵-△⁴ isomerase의 분포에 관한 연구

오선희,오재민,백용아,박옥규,정연태 대한해부학회 1988 Anatomy & Cell Biology Vol.31 No.3

천연 Zeolite를 이용한 매립지 침출수의 고농도 암모니아성 질소 제거에 관한 연구

오재일,홍성효,이선구,최영화,안봉규 중앙대학교 기술과학연구소 2002 기술과학연구소 논문집 Vol.32 No.-

천연 제올라이트의 일종인 Clinoptilolite를 이용하여 매립지 침출수내의 암모니아성 질소를 제거하는 실험을 수행하였다. 고정상 칼럼을 이용한 인공 침출수와 실제 침출수 조건의 실험에서 배출농도가 유입농도의 5%인 시점을 파과점으로 상정할 때, 인공 침출수 조건에서의 파괴시간은 53hr, 실제 침출수 조건에서의 파과시간은 32.5hr으로 나타났다. 또한, 허용 파과점 및 소모점에서의 제올라이트 100g(건조중량)당 제거된 암모늄 이온 성분량은 인공 침출수의 경우 각각 79.30meq/100g, 93.34meq/100g이었으며, 실제 침출수의 경우 각각 48.60meq/100g, 57.60meq/100g으로 나타났다. 침출수 조건의 경우 인공 침출수에 비해 약 39% 가량의 제거 효율 저하를 보이고 있으며, 이는 실제 침출수에 존재하고 있는 공존 양이온의 영향으로 사료된다. 실제 침출수 내에서 공존 양이온의 용출 특성을 보면, Na, Ca, Mg의 용출량은 증가하나 K는 용출량이 감소하는 것으로 나타났다. This experiment was conducted to remove the ammonia nitrogen in the landfill leachate by Clinoptilolite which is a sort of the natural zeolite. In fixed-bed column test driven in the artificial and actual condition of the leachate, when the ejection concentration was supposed the point of 5% of the initial concentration as the breakthrough point, the breakthrough time was 53hr in the artificial condition of the leachate and was 32.5hr in the actual condition of the leachate. The ingredient volume of the removed ammonium ion per 100g(based upon the dry weight) of the zeolite in the allowed breakthrough point and exhaustion point were individually 79.30meq/100g, 93.34meq/100g in the artificial leachate and 48.60meq/100g, 57.60meq/100g in the actual leachate. In case of the actual condition of the leachate, the removal efficiency was decreased by 39% than the artificial condition of the leachate, and it seems to be caused by the coexist cation in the actual leachate. The ejection characteristics of the coexist cation in the actual leachate was observed that Na, Ca, Mg was increased and K was decreased.

숯에 대한 考察

吳永仙,宋泰元 대전대학교 한의학연구소 2000 혜화의학회지 Vol.9 No.1

After analyzing the datas to propose the rightful recognition and research direction for the long used charcoal, the following conclusions are obtained. 1.The 'soot' is pure Korean which has the meaning of 'fresh power' and is translated in English as charcoal which is composition of china and cool meaning good. 2.The main dispositions of the charcoal are 85% of carbon, 10% of water, 4% of minerals and 2% of essential so that the understanding of properties and effects of carbon are essential. 3.It is usually appeared that there are purifying and detoxifying effects of the woods and the room in practical use of charcoal. 4.In everyday life, it removes the odors, regulates the humidity and prevents the decaying. 5.It is often used medically for activating liver functions, regulating digestive functions and for diseases with inflammations, fever or bleeding. 6.The charcoal is used in medical treatment internally as well as externally. Above conclusions shows that the objective research is needed for clinical use considering the physical and chemical properties in future.

성인의 급성 설사에 대한 로페라미드 옥사이드의 효과: 위약과의 무작위 이중 맹검 비교 다시설 시험

박영태,정희진,박중원,이계희,김나영,임선희,윤병철,한동수,이오영 大韓消化器病學會 1998 大韓消化器病學會誌 Vol.31 No.5

儀式으로 본 通度寺 空間動線 조사 연구

오흥선,이영한,박기홍,문종만,노정선 서울産業大學校 1999 논문집 Vol.49 No.2

This study deals mainly with relationships between the spatial composition and the Buddhist rituals of monks at the Tongdosa temple. The results of study are summarized as followed. Many of rituals are performed in the Sangrohjun(上爐殿) and, in particular, handled in the Sulbujun(說法殿), but not performed in the Jungrohjun(上爐殿) and Harohjun(下爐殿) except for the time of Buddhist mass held in the every morning and night. The main activities of all rituals were based on the Kumkang Stupa in the past and such a tendency continues in the present time. The characteristics of temple space reflected by the movement of monks and believers who take advantage of the Kumkang Stupa's Structure in the significant rituals such as the entrance of priesthood, reception of Buddhist confirmation, Buddha's Birthday and establishment of Tongdosa Temple.

Delftia sp. JK-2로부터 분리된 Catechol 2,3-dioxygenase의 정제와 특성 연구

황선영,오계헌 순천향대학교 기초과학연구소 2002 순천향자연과학연구 논문집 Vol.8 No.2

The purpose of this work was to investigate the purification and characterization of catechol 2,3-dioxygenase isolated from Delftia sp. JK-2, which could utilize aniline as the sole source of carbon, nitrogen and energy. In initial experiments, several characteristics of C2,3O separated with ammonium sulfate precipitation and DEAE-sepharose were investigated. Specific activity of C2,3O was approximately 4.72 unit/㎎. C2,3O demonstrated its enzyme activity to another substrates including catechol and 4-methylcatechol. The optimum temperature of C2,3O was 30℃, and the optimal pH was approximately 8. Metal ions including Ag^(+), Hg^(+), and Cu^(+2) showed inhibitory effect on the activity of C2,3O. Molecular weight of the enzyme was determined to approximately 35 kDa by SDS-PAGE.

병·의원에서 분리한 메티실린 내성 황색포도알균에서 SCCmec 유형과 Aminoglycoside 변형효소 유전자의 분포

정영희,김광욱,차정옥,이경민,유재일,유정식,김봉수,노영주,윤혜령,이영선 대한감염학회 2008 감염과 화학요법 Vol.40 No.1

목적 : 대부분의 AME 효소 유전자는 transposon이나 plasmid 상태로 전달되며 staphylococcal chromosomal cassette mec (SCCmec) 내에도 삽입되어 있다. 최근 MRSA의 SCCmec 유형에 따라 다양한 내성유전자를 가지는 것으로 보고되고 있다. 따라서 1, 2차 의료기관에서 분리된 황색포도알균의 항생제 내성률을 조사하고 MRSA에서 SCCmec type에 따른 AME 효소 유전자의 분포를 확인하였다. 재료 및 방법 : 2004년 1, 2차 의료기관에서 분리된 황색포도알균 640주를 대상으로 methicillin의 내성유전자 mecA와 AME 효소 유전자 aac(6')-aph(2"), aph(3')-IIIa, ant(4')-Ia 등을 multiplex PCR 방법을 이용하여 확인하였다. 항생제 감수성 시험과 MIC 값은 한천배지 희석법으로 확인하였고 SCCmec type도 결정하였다. 결과 : 640주의 황색포도알균 중 MRSA을은 39.7%였으며 MRSA 분리주 모두 mecA 유전자가 검출되었다. Aminoglycoside 중 kanamycin, tobramycin에 대한 내성률은 98.1%이었고, gentamicin 68.7%, amikacin 30.8%, netilomicin 2.8%이었으며 vancomycm에는 모두 감수성이었다. Oxacillin MIC_50과 MIC_90은 각각 128 ug/mL, 256 ug/mL이었으며 254주의 MRSA 중 214주를 선별하여 AME 효소 유전자를 확인한 결과 aph(3')-IIIa 13.1%, aad(6')-aph(2") 77.1%, ant(4)-Ia 53.3%이었으며 SCCmec type에 따라서는 type II, type III, type IV가 각각 50.9%, 16.4%, 32.7%였다. SCCmec type에 따른 AME 효소 유전자의 분포는 SCCmec type II에서는 aac(6')-aph(2")와 aac(6')-aph(2")/ant(4')-Ia가 각각 49.5%, 36.7%에서 검출되었고 type III에서는 aph(3')-IIIa/aac(6')-aph(2")가 60%, aac(6')-aph(2")가 31.4%, type IV에서는 aac(6')-aph(2")/ant(4')-Ia와 ant(4')-Ia가 각각 41.4%, 50%로 나타났다. 결론 : 1, 2차 의료기관에서 분리한 황색포도알균 분리주의 메티실린 내성률은 39.7%이었다. MRSA 분리주 중 SCCmec type II와 III에서는 aac(6')-aph(2")가, SCCmec type IV에서는 ant(4')-Ia가 90% 이상 검출되어 SCCmec type과 AME 효소 유전자 분포와는 연관성이 있는 것으로 나타났다. Background : Many genes encoding aminoglycoside modifying enzymes (AMEs) on transposon or plasmid were transferred from one strain to another strain and inserted into a staphylococcal chromosomal cassette mec (SCCmec). There are very diverse subtypes in SCCmec type to the insertion of resistant genes. Therefore, we researched the resistance rates of antibiotics and distribution of AME genes according to SCCmec type in MRSA strains. Materials and Methods : We isolated 640 Staphylococcus aureus from non-tertiary hospitals in 2004, detected mecA, aac(6')-aph(2"), aph(3')-llla, and ant(4')-la using the multiplex PCR method, tested antibacterial susceptibility disk diffusion and minimal inhibitory concentration, and determined SCCmec type. Results : Of 640 S. aureus isolates, MRSA rate was 39.7% and all MRSA isolates carried mecA gene. Among 214 MRSA selected, aminoglycoside-resistant rates were 98.1% in kanamycin and tobramycin, 68.7% in gentamicin, 30.8% in amikacin, and 2.8% in netilmicin. The detection rates for aac(6')-aph(2"), aph(3')-llla, and ant(4')-la were 77.1%, 13.1%, and 53.3%, respectively. Also, SCCmec type was 50.9% in SCCmec type II, 16.4% in type Ill, and 32.7% in type IV. The genes encoding AMEs were distributed aac(6')-aph(2") (49.5%) and aac(6')-aph(2")/ant(4')-la (36.7%) in SCCmec type II, aph(3')-llla/aaac(6')-aph(2") (60%) and aac(6')-aph(2") (31.4%) in type III, and aac(6')-aph(2")/ant(4')-la (41.4%) and ant(4')-la (50%) in type IV. Conclusion : 39.7% of S. aureus isolated from non-tertiary hospitals was resistant to methicillin. More than 90% of MRSA isolates were detected aac(6')-aph(2") in SCCmec type II and Ill, and ant(4')-la in type IV. With these results, the genes encoding AMEs may be closed related to SCCmec type.

호밀 유식물의 생장과 질산염 흡수에 대한 2,4-Dinitrophenol의 영향

임영선,권오영 충남대학교 자연과학연구소 1993 忠南科學硏究誌 Vol.20 No.2

This work has been accomplished to determine the effect of 2, 4-dinitrophenol on the growth and nitrate uptake in 6 days old rye(Secale cereale L.) seedlings. The shoot length and fresh weight have been increased in the groups as time go on, and the degree in the treated group has been lower than the control group. The dry weight has been decreased in both groups. The optimum pH for the nitrate uptake of the control group was 7.2 in the range of pH 4.5 - 8.5, but pH of the group treated with 0.5 mM 2,4-dinitrophenol has been gradually increased to 8.5. According to the treatment time in the solution of 10 mM KNO_3, the nitrate uptake has been increased for 2 hours in the control group, for 1 hour in the treated group, and then it has been decreased in both groups thereafter. With increasing of the concentration in the solution of KNO_3, the nitrate uptake has been promoted in both groups, and lower in the treated group than the control group. Consequently, it has been suggested that 2,4-dinitrophenol, one of the uncoupling agent in electron transport system, has inhibited the growth and nitrate uptake in the 6 day old rye seedlings.