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A New Sweetpotato Variety for Food and Starch, "Healthymi"
Young Sup Ahn,Byeong Choon Jeong,Mi Nam Chung,Joon Seol Lee,Hag Sin Kim 한국육종학회 2006 한국육종학회지 Vol.38 No.1
Healthymi is a new sweetpotato variety developed from Mokpo Experiment Station, National Institute of Crop Science(NICS), RDA in 2003, which was for the utilization as food and starch. This variety was selected from the cross between Seonmi and MI9001-12
백금박막 RTD를 이용한 유속센서의 제조와 그 동작특성
서현미,장경훈,김영진,설철규 경북대학교 센서기술연구소 1997 센서技術學術大會論文集 Vol.8 No.1
A flow sensor for detecting the flow rate of a air, composing a substrate, a heating element, and one or two fluid temperature sensing elements disposed symmetrically around the heating element. Wherein resistence changes by a fluid temperature change and heating element is maintained at fixed level by the control of voltage that is applied to the heating element. The function of the heating element(microheater) is based on the self-heating effect of the resistor when current is applied to it. A airflow sensor is capable of accuritely measuring a air flow irrespective of changes in ambient temperature. Pt thin films were deposited by a DC magnetron sputtering with Ar/O_(2) gas mixtures. Due to the oxygen incorporation into the Pt films, deposition rate and resistivity of as-deposited Pt thin films increased with oxygen fraction in the sputtering gas.
A New Sweetpotato Cultivar, "Matnami" suitable for Table Use
Joon Seol Lee,Hag Sin Kim,Young Sup Ahn,Mi Nam Chung,Byeong Choon Jeong,Jin Ki Bang 한국육종학회 2007 한국육종학회지 Vol.39 No.2
“Matnami” is a new sweetpotato variety developed by Mokpo Experiment Station, National Institute of Crop Science (NICS), RDA in 2006, for table use and food processing. This variety was selected from the cross between “Hongmi” and MI9510-12 in 1999. Seedling and line selections were performed from 2000 to 2002. Preliminary and advanced yield trials were carried out from 2003 to 2004. The regional yield trials were conducted at six locations from 2005 to 2006. “Matnami” has cordate leaf, green with purple vine and petiole, elliptic storage root, red skin and yellow flesh color of storage root. The average yield of storage root was 27.0 ton/ha in the regional yield trials, which was 11% higher than that of Yulmi variety. Number of storage roots over 50 gram per plant was 2.6. The average weight of one storage root was 173 gram. This variety is also resistant to fusarium wilt and nematode. In addition, steamed “Matnami” has higher polyphenol contents as 3.3 mg/g dw and higher biological activitiesas, which improve the bioactivity in human. The total sugar content was higher, thereby, sweeter than “Yulmi”. It shows lower (68.6℃) initial temperature of starch gelatinization and slower retrogradation process than “Yulmi”.
Chitin과 Chitosan이 흰쥐의 Cadmium중독과 지방대사에 미치는 영향
김미경,설은영 이화여자대학교 생명과학연구소 1994 생명과학연구논문집 Vol.5 No.-
This study was performed to investigate the effect of dietary chitin & chitosan on cadmium(Cd) toxicity and lipid metabolism in rats. Forty-two male rats of Sprague-Dawley strain weighing 137+-g were blocked into 6 groups according to body weight, and were raised for 4weeks. Cadmium chloride was given at the level of 0 or 400ppm in diet and chitin and chitosan wre given at the level of 0 or 4% (w/w) of diet. The results are summarzed as follow. Chitosan decreased the toxicity of Cd on liver, kidney and femur and increase the Cd content of fecal excretion. Chitosan increased the lipid & cholesterol content of fecal excretion by combining with lipid and bile acid. Chitosan decreased lipid, cholesterol and TG content in serum and liver by combining with lipid and bile acid. Chitin was less effective than chitosan in decreasing of Cd toxicity and lipid content of rat.
‘병동 중심의 처치수가 산정지침 개발’ 등을 통한 간호업무 표준화 및 그 효과
한혜정,설미진,김영주,박소영,박아리스,문한경,이현영 한국의료QA학회 2009 한국의료질향상학회지 Vol.15 No.1
문제: 병동 처치수가 산정 부정확 및 누락으로 인한 부적절한 재고관리로 진료차질, 불필요한 업무발생 및 수익이 감소한다. 목적: 병동 처치수가 산정 정확화를 위한 업무 표준화 도구 및 시스템을 개발하여 적정 재고관리를 통한 수익증대 및 직무만족도를 향상시킨다. 의료기관: 서울시 종로구에 소재한 대학병원 질 향상 활동: 병동중심의 처치 산정지침 개발 및 수가물품의 적정재고 관리방안을 모색하였다. 개선효과: 병동중심의 처치수가 산정 지침서를 제작하여 업무표준화를 기하였음. 응급청구 품목 및 수량이 ’07년 대비 71%감소하고 타 병동 차용품목이 활동 전에 비해 61% 감소, 수량은 77% 감소함. 응급청구 총소요시간이 활동 전에 비해 ’07년 대비 77% 감소하고 타 병동 차용 총 소요시간이 61% 감소함. 전년 동기간 대비 수익이 4% 증가하였으며 또한 54병동과 보험 심사팀에서 직원들의 직무만족도가 향상되었다.
박지훈,이상혁,김희,이재호,박성재,지삼룡,양성연,박은택,이연재,설상영,정정명,강미선 白中央醫療院 2005 仁濟醫學 Vol.26 No.1
Fungus such as Candida albicans is a normal flora that is frequently found in the oral cavity, gastrointestinal tract, genitourinary tract, vaginal mucosa in a normal person. However, candida can cause opportunistic infection in an immune compromised host. Candidiasis has broad spectrum of disease from mucocutaneous infection to invasive or disseminated infection. But, it is rarely reported that candida is associaed with gastrointestinal tract disease in a healthy adult. The case of gastric ulcer associated with candida particularly in a health adult is reported with relevant literature.
Seol, Young Mi,Kwon, Chae Hwa,Lee, So Jeong,Lee, Seon Jin,Choi, Yuri,Choi, Young Jin,Kim, Hyojeong,Park, Do Youn Neoplasia Press 2019 Translational oncology Vol.12 No.2
<P>With the advent of next-generation sequencing (NGS), targeted sequencing is now contributing to decision making for which chemotherapeutics to administer to cancer patients, especially in refractory and metastatic cancer. Given that most patients with refractory cancer develop resistance to chemotherapy and have few treatment options, we performed NGS test to evaluate the efficacy and clinical feasibility of NGS-based targeted anticancer therapy. We used a gene panel for capturing target regions covering 83 cancer-related genes. A total of 25 refractory metastatic solid tumor patients were enrolled in this study. Among the 25 patients, 7 had FDA-approved drug-responsive or -resistant alterations. However, the effectiveness of targeted therapy was assessed by follow-up in three patients (12%). These included crizotinib for ALK-EML4 fusion in a malignancy of undefined origin patient and everolimus for <I>AKT3</I> amplification in a uterine sarcoma patient. In addition, we identified a <I>KRAS</I> codon 146 mutation (A146V), which is associated with resistance to anti-EGFR, in a cetuximab-resistant colon cancer patient with wild-type <I>KRAS</I> exons 2 and 12, and <I>EGFR</I> amplification. He received bevacizumab therapy. All three patients showed partial response after targeted therapy. Furthermore, we characterized <I>KRAS</I> A146V biologically using colon cancer cells. In conclusion, this study suggests that targeted therapy based on NGS test may be a good choice for improving the care of patients with refractory solid tumors.</P>
Agricultural Omics Information Submission to NABIC
Young-Joo Seol,Mi-kyoung Kim,Chang-kug Kim,Jang-ho Hahn,Dong-Suk Park 한국육종학회 2012 한국육종학회 심포지엄 Vol.2012 No.07
NABIC(National Agricultural Biotechnology Information Center) established integrated management system of agricultural omics information to achieve the agricultural bio-information resources of Korea. The amount of bio-information is enormously increasing due to emergence of NGS(Next Generation Sequencing) technology. We has building, maintaining and providing agricultural bio-information databases and information services. Various data type for submission is available such as genome, proteome, transcriptome, metabolome, molecular marker, etc. We issue the submission confirmation which is available for research achievement. Currently, the amount of data submitted on our system is 4.3Tb. We are planning to integrate genome annotation system and NGS analysis system this year. The Agricultural Omics Information Submission System is available through web site(http://nabic.naas.go.kr/submission).
Seol, Young Mi,Kwon, Bo Ran,Song, Moo Kon,Choi, Young Jin,Shin, Ho Jin,Chung, Joo Seop,Cho, Goon Jae,Lee, Jin Chun,Lee, Byung Joo,Wang, Soo Geun,Kim, Hak Jin,Kim, Won Taek,Kim, Seung Jang,Yun, Eun You Acta Oncologica 2010 Acta Oncologica Vol.49 No.2
<P>PURPOSE: To evaluate the prognostic value of the metabolic tumor volume measured on 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) imaging and other clinical factors in patients treated for locally advanced head-and-neck cancer (HNC) at a single institution. MATERIALS AND METHODS: Between June 2005 and August 2008, 59 patients with HNC that underwent pretreatment FDG-PET studies received neoadjuvant chemotherapy and radiation therapy. Metabolically active tumor regions were delineated on the pretreatment PET scans by a fixed SUV of 2.5. We evaluated the relationship of the 18F-fluorodeoxyglucose-PET maximum standardized uptake value (SUV) and the metabolic tumor volume (MTV) with the progression-free survival (PFS) and overall survival (OS). RESULTS: The MTV and lymph node metastasis were predictive of the PFS and OS. The lymph node status did not correlate with the MTV. A higher MTV of 9.3 cm(3) was significantly associated with an increased risk of recurrence (2.19-fold, p = 0.006) and death (1.62-fold, p = 0.051). Separation of patients with tumor volumes <or= 9.3 cm(3) and no lymph node disease vs. any other combination was strongly predictive of the PFS and the OS. CONCLUSIONS: MTV and lymph node status were prognostic values associated with survival. Quantitative measurement of tumor volume separates patients with a good prognosis from those with a poorer prognosis. A subset of patients with relatively small tumors and no lymph node involvement did very well.</P>