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Novel Repair Technique for Articular Cartilage Defect using a Fibrin and Hyaluronic acid Mixture
( Jae Deog Jang ),( Young Seok Moon ),( Yong Sik Kim ),( Nam Yong Choi ),( Hyun Su Mok1 ),( Young Ju Kim1 ),( Asode Ananthram Shetty ),( Seok Jung Kim ) 한국조직공학·재생의학회 2013 조직공학과 재생의학 Vol.10 No.1
We evaluated the cartilage repair potential of a hyaluronic acid and fibrin mixture when transplanted into cartilage defects. Circular, articular, cartilage defects 4-mm in diameter were made in the trochlear region in 21 New Zealand white rabbits divided into three groups. The seven rabbits in the control group underwent microfracture (M group), the seven rabbits in the experimental group underwent microfracture with subsequent injection of hyaluronic acid mixed with fibrin (MH group), and seven rabbits in the other experimental group underwent microfracture followed by injection of bone marrow concentrate and hyaluronic acid mixed with fibrin (MBH group). At week 12 following surgery, the cartilage was observed and histologically compared in the three groups. The surface of the newly generated cartilage was very smooth and even, and we noticed that the entire area was completely regenerated in both experimental groups. The control group showed incomplete and irregular cartilage formation in the defect. In histologic scoring, comparison of the MBH group (M= 2.333) and the M group (M= 9.000) differed significantly (P= 0.046). Therefore, injection of a mixture of bone marrow concentrate, hyaluronic acid and fibrin to treat articular cartilage defects of the knee appears to be an effective method of cartilage regeneration.
국부 마모 부품을 위한 레이저 표면강화 열처리에 관한 연구
이목영,김형준,김기철,김재웅 한국레이저가공학회 2002 학술발표대회 Vol.2002 No.1
두께 10mn 일반기계구조용강재를 사용하여 레이저 종류에 따른 표면경화 열처리특성에 관하여 알아보았다. 경화층의 형성은 레이저의 종류에 크게 영향을 받았는데, 표면경화 열처리를 위해서는 파장이 짧은 Nd-YAG 레이저를 사용하는 것이 유리하였다. 경화층의 최고경도는 700Hv 가량으로 높게 나타났으며, 레이저 표면경화 열처리는 상온에서 사용되는 부품의 내마모성 향상 특히 국부 마모를 겪는 부품에 효과적일 것으로 판단되었다.
정재헌,김정수,김종민,김영한,이상록,장상목 동아대학교 공과대학부설 생산기술연구소 1997 生産技術硏究所硏究論文集 Vol.2 No.1
In this study, the equipment and method to recyle waste-paint, were developed and investigated. The efficiency of drying and pulverizing the waste-paint were improved via vescosity reducing process and microwave energy source with a blast of hot air. This method may be useful to recyle the waste-paint, rubber and plastics.
폐렴 구균(Streptococcus pneumoniae)에 의한 척수 경막외 농양 1예
이지영,위유미,손경목,기현균,문치숙,오원섭,백경란,송재훈 대한감염학회 2004 감염과 화학요법 Vol.36 No.6
폐렴구균은 보통 폐렴이나 뇌막염을 일으키는 균으로 척수 경막외 농양을 일으키는 경우는 매우 드물다. 본 저자들은 폐렴 구균에 의한 척수 경막 외 농양을 경험하여 보고하는 바이다. 과거 건강했던 36세 남자 환자로 사다리에서 낙상한 후 요통 및 고열, 신경학적 이상으로 내원하여 자기 공명 촬영 결과 척수 경막 외 농양으로 진단받고 항균제 투여와 함께 응급 수술을 시행하였다. 농 배양 결과 페니실린 감수성인 폐렴 구균이 분리 되었고, 수술 요법과 항생제 투여 후 농양은 치유되었으나 신경학적 이상은 호전 없는 상태로 타원으로 전원되었다. Pneumonia and meningitis are the most frequent manifestations of pneumococcal infections. Pneumococcal spinal epidural abscesses have been rarely reported. Spinal epidural abscess by Streptococcus pneumoniae has been diagnosed among the patients with diabetes mellitus, alcoholism, corticosteroid therapy, intravenous drug use, chronic renal failure, AIDS, and history of spinal surgery. Recently, we experienced a case of pneumococcal spinal epidural abscess after spinal trauma. A 36-year-old male patient was admitted with back pain, fever, and paraplegia which occurred 5 days after the trauma. Spine MRI revealed spinal epidural abscess at the level from T2 to T9. He was treated with antimicrobial agents and surgical exploration for spinal epidural abscess. Pus culture grew S. pneumoniae which was susceptible to penicillin. Despite early surgical treatment, neurologic sequelae remained. Considering the high mortality and morbidity of pneumococcal spinal epidural abscess, early diagnosis and aggressive treatment including surgical intervention and antibiotics therapy should be implemented immediately.
이목영,김재웅,김기철 한국레이저가공학회 2003 학술발표대회 Vol.2003 No.1
두께 2.0mm 열연강판을 대상으로 GMA 용접과 Nd:YAG 레이저 용접의 복합화에 따른 용접성을 알아보았다. GMA 용접과 레이저 용접의 공정 변수를 제어하므로서 용접부 크기제어가 가능하였으며, 특히 합금량이 높은 경우에는 filler의 성분을 조절하여 용접비드의 야금학적/기계적 특성 제어가 용이하였다. 레이저-아크 하이브리드 용접은 알루미늄 혹은 고강도강과 같이 용접이 어려운 소재의 용접에 적당하였으며, 상대적으로 낮은 출력의 레이저를 사용하므로서 용접 cost의 저감이 가능하였다.
시토크롬 C의 전기화학반응에 있어서 프로모터와 전해질과의 영향
최광재,조홍식,이행자,장상목,김영한 동아대학교 환경문제연구소 1999 硏究報告 Vol.22 No.1
The electrochemical reaction of cytochrome C varied with promotors and electrolytes. Among electron transfer carriers, 4-4' bipyridine(PyPy) showed good redox response using 20 mM phosphate solution as electrolyte and the case of Bis(4 pyridyl) bisulphide(PySSPy) as promotor showed same result using 0.2M Sodium cacodylate as electrolyte tested cyclic voltammetry method. Between electrodes, Au electrode is better behaviour than ITO electrode. 0.21M Tris, 0.24M Cacodylate acid showed the most effective electrochemical characteristics as electrolyte.
廷基榮,李在睦 東國大學校 1999 東國論叢 Vol.38 No.-
This research is focusing on the practice dealing with the Consumer Bankruptcy(C.B.) and its legislative debate in Japan. The reason why we are focusing on that subject is as following; First, The Korea Bankruptcy Act has been rooted from that of Japan in 1952 and therefore has the same ground of interpretation. Secondly, owing to Japanese bubble economic and the prolonged depression, the number of C.B. cases has already exceeded more than 100,000. In japan, from the middle of 1970's, analytical and legislative debate about C.B. has started frequently and the know-how of legal management of that matter has been accumulated enough. Korea has experienced the IMF crisis in 1997 and the number of C.B. cases has increased slowly. But we have not managed that well, therefore we can take such a Japanese analytical and legislative debate for reference. In this study, the author emphasize the debate on discharge of bankruptcy. Because that is the hot issue of C.B. problems. the author concluded that the excessive extension of discharge should be restrained deliberately. Because it has apprehension to cause the excessive sacrifice of creditor and the destructions of the 'pacta sund servanda' rule in private law. In further discussion on C.B. problems, we should consider elaborately the essential meaning of discharge, the settling of the conflict of interests between parties, and the nation's legal sense. The contents of this treatise are as follows; Ⅰ. Introduction Ⅱ. Present conditions of C.B. in Japan 1. Change of C.B. cases 2. Cause of increase of C.B. Ⅲ. Chief issues of C.B. 1. Characteristic of C.B. procedure 2. Theory of discharge (1) Meaning and history (2) Constitutionality (3) Idea and essence (4) Other problems Ⅳ. Problems of the system of C.B. and legislative assignment