급성심근경색증을 가진 한국인에 있어 Chlamydia Pneumoniae 감염의 영향에 대한 연구

이은미,오동주,황교승,안정천,송우혁,임도선,박창규,김영훈,서홍석,심완주,노영무,정희진,김우주,김종헌,송기준 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.4

Repellent efficacy of essential oils and plant extracts against Tribolium castaneum and Plodia interpunctella

Lee Hwa‐Eun,Hong Su Jung,Hasan Najmul,Baek Eun Joo,Kim Jun Tae,Kim Young‐Duk,Park Mi‐Kyung 한국곤충학회 2020 Entomological Research Vol.50 No.9

This study was conducted to investigate the repellent efficacy of essential oils (Origanum vulgare, Pimpinella anisum, and Tanacetum cinerariifolium) and four plant extracts (Agastache rugosa, Capsicum annuum, Citrus reticulata, and Ginkgo biloba) against Tribolium castaneum (adults and larvae) and Plodia interpunctella (larvae). Gas chromatography/mass spectrometry analysis revealed the presence of carvacrol, anethole, and jasmolin I as the predominant constituent in O. vulgare, P. anisum, and T. cinerariifolium, respectively. Furthermore, ethyl hexopyranoside, 9,12‐octadecadienoic acid, cyclopentanol, and 2‐cresol were identified in A. rugosa, C. annuum, C. reticulata, and G. biloba, respectively. The repellent efficacy of each essential oil, plant extract, and the combination of oils was evaluated using a specially designed cylinder trap for 120 h. Among the three oils, O. vulgare and T. cinerariifolium had greatest repellent efficacy against P. interpunctella larvae. T. cinerariifolium exhibited effective repellence against the adults and larvae of T. castaneum. Therefore, O. vulgare (O) and T. cinerariifolium (T) were selected for further investigation of combined effects. Two essential oils were mixed in three different ratios of OT1 (1:3), OT2 (1:1), and OT3 (3:1). The repellent efficacies of OT1 and OT2 against the adults of T. castaneum were significantly greater than that of OT3. OT1 was effective against the larvae of T. castaneum, whereas OT2 was effective against the larvae of P. interpunctella. OT1 enhanced the repellent efficacy by approximately five times against larvae of T. castaneum, compared with that of T. cinerariifolium. Overall, OT1 was selected as the best repellent substance against all the tested insects.

Multiple myeloma 환자에서 Bortezomib치료 후 발생한 마비성 장폐색증 1례

김준영,이원식,손창학,박성길,진한영,박석주,조영완,정은욱,강명주,박정하,주영돈 인제대학교 2006 仁濟醫學 Vol.27 No.-

Bortezomib is the first clinically available proteasome inhibitor that is clinically effective in the treatment of multiple myeloma. A proteasome inhibitor acts through multiple mechanisms to arrest tumor growth, tumor spread, and angiogenesis. The main adverse effects of bortezomib are gastrointestinal symptoms, cytopenia, fatigue, and peripheral neuropathy. To date, severe paralytic ileus has not been reported as a toxic effect of bortezomib treatment in multiple myeloma. Bortezomib is a novel agent that has only been used clinically for 30 months, so a need exists to further evaluate its toxicity. We report a case of grade Ⅲ (NCI CTCAE v3.0) or grade Ⅳ(SWOG toxicity criteria) paralytic ileus in a 65-year-old man with relapsed multiple myeloma who underwent one cycle of single-agent bortezomib treatment scheduled in a 21-day cycle (1.3 mg/㎥ as a single i.v. bolus on days 1, 4, 8, and 11).

서울의 PPNG 발생 빈도(1991-1992)

김재홍,윤기범,박평원,김영진,전경민,김영태,김중환,곽호,구상완,송민석,유옥,지혜구,김동원,문상은,박영립,정승호,성범진,성순제,엄주용,황정열,이기홍,이주협,전태진 대한화학요법학회 1994 대한화학요법학회지 Vol.12 No.1

The prevalence of PPNG among pretreated gonorrhea cases isolated at the STD clinic of Choong-Ku Public Health Center in Seoul has been studied and reported annually since 1981. In 1991, 123 strains of N.gonorrhoeae were isolated, among which 58(47.1%) were PPNG. In 1992, 98 starains of N.gonorrhoeae were isolated, among which 51(52.0%) were PPNG. In all, 109(49.3%) strains were found to be PPNG among 221 strains isolated between 1991-1992. The prevalence of PPNG in Seoul showed increased tendency till 1989, thereafter, it has been stationary or slightly decreasing.

암치료에 있어서 체질과 항암효과에 관한 한의학적 연구

성현제,신현규,박갑주,강봉주,은영아,김은해,정세영 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

As one of the chemical and experimental study on cancer treatment in Korea oriental medical hospital. Furthermore, we carried out the cytotoxicity test of extracts of herbal medicine. The results are as follows : About Clinical Aspects of the Oriental Medical Cancer Treatment - (1) Clinical experience is that 420 Oriental medical hospital were surveyed. Number of cancer patient treated by one oriental medical doctor was under 10(about 60%) or from 10 to 20(about 30%). (2) Diagnostic Procedure is that more than 80% of cancer patients were diagnosed by medical doctor of western hospital. (3) Therapeutic Method is that combination of oriental and western medical treatment was used in oriental medical hospital. (4) Relationship between cancer and constitutions is that to the relationship between cancer and constitutions, about 75% responded and most were considered to be Um. About Experimental Study - to evaluate the direct cytotoxicity of hot water and methanol extracts of 34 oriental medical presciptions on stomach cancer cell, SRB assay was carried out. (1) The IC50 value of water extract of Samsoum was 19㎍/㎖ and that of methanol extract was 15㎍/㎖, so that we confirmed Samsoum has a strong direct cytotoxicity. (2) The IC50 values of water extract of Coptidis Rhizoma, methanol extract of Caesalpiniae Lignum and Draba Semen were 10㎍/㎖, 19㎍/㎖ and 12.5㎍/㎖ respectively, so that we confirmed Coptidis Rhizoma, Caesalpiniae Lignum and Draba Semen have a strong direct cytototoxicity. (3) The IC50 value of combinatory prescription of Rhei Rhizoma, Forsythie Fructus and Caesalpiniae Lignum was about 40㎍/㎖.

부의 양육참여와 아동의 사회적 능력과의 관계에 관한 고찰

은주영,류도희,이귀옥 경성대학교 2001 論文集 Vol.22 No.1

This paper reviewed the father's influence on his children's social ability. Traditional fathers were firm and demanding, authoritarian, and possessed the bulk of the power in their families. Recently, father's role on his family has been changed in that more fathers get involved in their children's bringing up. Fathers' instrumental role has negative effects on the emotional lives of fathers and their children, while when fathers show more affective and acceptive in fathering, their children develop highly in their social and intellectual ability. In order to increase paternal involvement, social supports is needed such as more flexible work schedule.

소금쟁이의 성장인자 분석

주은영 慶山大學校 1997 論文集 Vol.15 No.1

The study was attempted to analyze the changing patterns of growth for the eight body parts, through the growth in all five immatures and adult stage of Gerris paludum insularis. The factor analysis was employed by Holzinger and Harman(1941). The results are summarized as follows :A11 eight variables are found to have three factors affecting the growth of G. paludum insularis. The first factor is contributes to a general factor. The second and third factors are acceptable as a group factor showing the different direction of action by the variables. The communality of the mid1eg(0.8842) is the greatest, and is decreased in the following order, the pronotum width, the hindleg, the foreleg, the body length, the head width, the antenna, and the rostrum(0.3199). The unigueness of the rostrum (0.6801) is the most significant, while that of the mid1eg(0.1159) is less significant. The body parts in a young instar larva have a weak relationship, while an advanced instar larva has a strong relationship.

責任保險에 관한 硏究

朱榮殷 서경대학교 1983 論文集 Vol.11 No.-

Liability insurance is a property insurance contract which is for the purpose of having the insurer make indemnification thereof, if the insured is liable for damages against a third person during the period of the insurance policy's validity. Liability insurance is classified as business liability, proffesional liability and personal liability according to the causes of the creating of liability. Liability insurance has social functions that protect the insured, who is liable for damage, and the injured third person together. It is said that the history of liability insurance is the process of switching from the protection of the insured to that of the injured person. Because the object of liability insurance is liability for damages the insured is liable for the third person, liability insurance differs from general property insurance whose subject is specific property. The insurable interest in liability insurance is interpreted as interest the insured has on all of his properties. Property insurance is a contract of indemnity. Thus, though the interest of the insured does not have a specific value presently calculable, if the hazard or risk insured against is such that its future occurrence may result in loss to the insured, there is a sufficient interest. A person has an insurable interest in property when he may be subject to pecuniary loss should the property be damaged or destroyed, even though he may have no title to it, no lien upon it, nor right to possession. In defining insurable risk, it would be proper to accept "the claim made basis" which defines that the insurable risk is for the insured who caused the accident to receive a claim for damages on liability from the third person. We have to admit that it is because of the provisions of the law that the third person, who doesn't have the privity of contract, has the right to demand directly that the insurer make indemnification against the loss.

한국인에서 NOTCH4 유전자 내 두 개의 단일염기다형성과 정신분열병의 연합연구

주은정,정성훈,김미재,구영진,배승오,안용민,이규영,김용식 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : Previous studies on N0TCH4 gene and schizophrenia have not produced consistent results, and more studies with various ethnicities and populations were warranted. This study was performed with Korean population to find the role of the N0TCH4 gene in the development of schizophrenia. Methods : 235 schizophrenics and 236 normal controls participated in the study. Two SNPs (-1725 A/G and -25 T/C) on the N0TCH4 gene were investigated. Genotyping was done by Taqman assay, and statistical analysis was done by contingency chi-square test for the allele and genotype frequencies and PowerMarker V3.0 for the haplotype. Results : The two SNPs did not deviate from Hardy-Weinberg equilibrium in neither schizophrenics or normal controls. Two groups were not different in terms of allele and genotype distribution for both SNPs. Two SNPs were found to be in linkage disequilibrium. Haplotype analysis could not find an association between schizophrenia and these two SNPs. There was no association between the age at onset and the genotypes for both SNPs. Conclusion : We could not find any significant association between schizophrenia and the N0TCH4 gene in this Korean population. Although there are limitations in this study, this result supports the conclusion that the N0TCH4 gene is less likely to play a major role on the development of schizophrenia in the Asian population.

장기간 보관한 멸균물품의 오염 상태에 관한 연구

주홍순,조순덕,정재심,신동분,임바올라,노은지,이선희,송영미,최정화,백병윤,김미나 대한병원감염관리학회 2003 의료관련감염관리 Vol.8 No.1