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      • KCI등재

        푸른길 공원의 대기 환경 특성에 관한 연구

        민경우,이경석,박옥현,윤관주,김도술,박세일,정원삼,이대행,조영관,Min, Kyoung-Woo,Lee, Kyoung-Soek,Park, Ok-Hyun,Yoon, Kwan-Ju,Kim, Do-Sool,Park, Se-Il,Jeung, Won-Sam,Lee, Dae-Hang,Cho, Young-Gwan 한국환경보건학회 2015 한국환경보건학회지 Vol.41 No.3

        Objectives: This study aimed to survey the characteristics of air quality and meteorological conditions in a greenway park. Methods: We measured meteorological and health related factors, including noise, particulate matter ($PM_{10}$) and selected gaseous air pollutants at three locations in a greenway park and on a general roadside as comparison. The measurements were repeated four times from April to October 2014. Results: The average air temperature in the greenway park was $20.7^{\circ}C$ which was $1-2^{\circ}C$ lower than on the general roadside. The average $PM_{10}$ concentration in the greenway park was $85.0{\mu}g/m^3$, a level 2-3 times lower than that at the roadside. The noise level at the greenway site was 4.4 dB(A)- 23.0 dB(A) lower than at the roadside. The average CO, $CO_2$, $SO_2$ and NOx concentrations in the greenway park were lower than at the roadside. The average phytoncide and anions concentrations in the greenway park were higher than at the roadside. Conclusions: The urban forest of the greenway park may have some impact on air quality and meteorological conditions.

      • 신생아에 심한 심부전증을 일으킨 선천성 뇌동정맥 기형: 풍선 색전 요법을 시도한 1례

        박인숙,김영휘,홍창의,조영국,서대철,박영일 울산대학교 의과대학 1993 울산의대학술지 Vol.2 No.2

        Cerebral arteriovenous malformation is a rare cause of congestive heart failure in neonates and is known to carry a very poor prognosis even wish prompt recognition and aggressive treatment. We recently encountered a 2-day-old male neonate with huge cerebral arteriovenous malformation who presented with intractable heart failure. Despite aggressive medical treatment and partial embolization with detachable balloon, baby died of severe hearts failure. Since there is no report of percutaneous balloon embolization in a neonate with this lesion in Korean literature, we wish to present our experience in one such neonate. Also we believe this is the first report of color Doppler findings in cerebral arteriovenous malformation in Korean literature.

      • KCI등재후보

        흰쥐 Kupffer 세포에 대한 Propofol의 작용

        박세훈,지대림,성언기,김희선,송인환,박희영,김준수,이덕희,박대팔 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.43 No.4

        Background: Propofol has an antioxidant capacity and can be used for ischemia-reperfusion injury of the liver. However, the effects of propofol on the Kupffer cells have not been establisked. Methods: Kupffer cells were isolated and cultured from male Sprague-Dawley rats. The effects of propofol on the Kupffer cells were evaluated by a phagocytosis assay, TNF-α gene expression, and superoxide anion release after administering propofol in different concentrations on the cultured Kuprrer cells. Results: The latex bead phagocytosis by the Kupffer cells was suppressed when the Kupffer cells were exposed to propofol irrespective of concentrations. Higher propofol concentrations decreased the loss of Kupffer cells after latex bead phagocytosis. Propofol induced TNF-α mRNA expression in the Kupffer cells, but the mRNA expression level after 50㎍/ml of propofol decreased. The pattern of TNF-α mRNA expression induced by propofol was different to that induced by LPS: TNF-α mRNA was expressed continuously in the propofol-treated cells until 16 hours after exposure to propofol, whereas the level of TNF-α mRNA expression induced by LPS was evident after 2 hours and was not found thereafter. TNF-α production after propofol treatment was not higher than that of the control. Formazan presipitation did not show any qualitative differences between cells untreated or treated with propofol concentrations of 0.5, 5.0, and 50 ㎍/ml. Conclusions: These results showed that propofol might inhibit Kupffer cells. This suggests that propofol and be used for patients with ischemia-reperfusion injury of the liver. (Korean J Anesthesiol 2002; 43: 475~484)

      • 연산반응법을 이용한 녹지 관련용어의 의미분석에 관한 연구

        박찬용,이영대 영남대학교 지역발전연구소 1997 새마을지역개발연구 Vol.20 No.-

        This research aims at investigating how the public understand greenery related concepts and what kind of images of the concepts they have employing the associative response method. The analysis result shows that the public's responses to the greenery related concepts are relatively confined to specific terms. In case of natural environment, people assoicate it not only with "clean and pure" but also with "preservation and protection" that are attributable to their strong respones against destruction of natural elements such as hill, tree, woods, water, river and stream by pollution and waste warer. People strongly respond to greenery in terms of vegetative covers independent of continuity of open space and ownership. People assoicate parks primarily with functions of recreational places such as rest and walk. Parks are associated more with artifacts than other concepts. The concept of "green" is realted with positive responses such as "pleasurable, beautiful, clean, serene." The concept of "greenery" is most highly related to the concept of "green" and the concept of "pleasurable, environment" is lastly related to the concept of "park." This is because natural environment, greenery and green have common natural elements while parks consist of relatively more artifactual elements than other entities. Based on these findings, it is recommended that further survey research emlpoying samples of public subjects heed on communications of exact meanings and selection of related concpets.

      • 태권도 선수의 인지 재구성에 의한 시합 불안 감소 연구

        박영수 ( Young Soo Park ),양대승 ( Dae Seung Yang ),서진교 ( Jin Gyo Seo ) 국기원 2010 국기원태권도연구 Vol.1 No.1

        본 연구의 목적은 김용승(1996)이 개발한 심리기술 강화 훈련 프로그램(시합불안 제어용)의 단축형을 스포츠 현장의 태권도 선수 남녀 2명에게 적용하고 그의 시합불안 제어효과를 조사하고자 하는 것으로 2개의 1인 대상연구 형태로 이루어 졌다. 개입프로그램은 합리적 정서적 치료(RET) 및 합리적 인지 재구성(CRR)을 기반으로 하여 개발된 것으로, 현장에서 심리학적 전문지식이 없어도 적용이 가능하도록 127개의 진술 항목이 개발되어 포함되어 있다. 대상은 남녀 대학 태권도 선수 2명이며 평소 시합불안 제어가 필요함을 표현하던 선수였다. 연구개입은 각각 4회기에 걸쳐 이루어졌고, 개입 전후에 SCAT 검사를 하여 특성 시합불안의 변화를 조사하였다. 개입 후에는 보충면접(Back-up Interview)을 통해 1인 대상 연구의 단점을 보완하고자 하였다. 남자 P의 경우 개입 프로그램 전후의 SCAT 점수는 15점에서 14점으로 1점의 감소를 보였으나, 보충면접을 통해 개입 프로그램이 시합 불안을 낮추는데 효과가 있었다는 것이 밝혀졌다. 피험자 L의 경우도 개입 프로그램 전의 점수가 20점이었으나 프로그램 개입 후의 점수는 12점으로 대폭 감소하여 개입 프로그램이 L의 시합 불안을 급격하게 감소시킨 것으로 나타났으며, 보충면접에서도 L은 개입 프로그램으로 시합 불안이 크게 감소하였다고 진술하였다. 따라서 이 프로그램은 태권도 선수들의 시합 시 불안을 감소시킬 뿐만 아니라 훈련 시에도 개입효과를 기대할 수 있다. This study aims to apply the simple version of Mental Technique Enhancing Training Program (for controlling game anxiety) developed by Young-Seung Kim (1996) to 2 Taekwondo players (male and female) in the sports field and to research the game anxiety control effect and was composed of 2 one-person studies. The intervention program was developed based on Rational-Emotive Therapy (RET) and Cognitive, Rational Restructuring (CRR) and is composed of 127 statement items developed for this research so that it can be applied without psychological expertise in the field. The subjects were 2 college taekwondo players who needed to control game anxiety usually. The intervention was performed 4 times for each player and examined the change of game trait anxiety by SCAT test before and after the intervention. Back-up interview was conducted to compensate for the weakness of one-person study after intervention. In case of male subject P, the SCAT score decreased from 15 to 14 after the intervention but it was concluded through the back-up interview that the intervention was effective in reducing game anxiety. In case of subject L, the SCAT score sharply decreased from 20 to 12 after the intervention, showing that the intervention program reduced game anxiety drastically. The subject L also stated that the game anxiety was reduced greatly due to the intervention in the back-up interview. Thus, it was concluded that this program can not only reduce anxiety during a game for taekwondo players but also have anxiety control effect during training session.

      • 만선신부전 환자에서 관상동맥조영술 소견에 관한 연구

        한대희,김성구,박상호,김성한,조원영,방덕원,조윤행,정의룡,은영근,권영구 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1

        Background : Patients with chronic renal fialure have a substantially elevated risk of death from cardiovascular diseases than do the general population. the patients with chronic renal failure are at significantly increased freqeuncy of hypertension, hyperlipidemia, and diabetes mellitus which are known to the risk factors of the coronary artery diseases, and the prevalence of the coronary artery diseases in chronic renal failure patients is highly associated with the hemodynamic disorder and metabolic abnormalities. therefore we expected that the coronary angiographic findings in patients with chronic renal failure should be different from the general population (control groups) and investigated the risk factors contributing to coronary artery diseases. Method : we have retrospectively compared the coronary angiographic findings of 44 patients with chronic renal failure on hemodialysis with that of 88 patients in the general population and investigated the factors contributing to the development and acceleration of coronary artery diseases in patients with chronic renal failure Result : Hypertension and diabetes mellitus which is risk factors for coronary artery disease is significantly increased in patients with chronic renal failure, in coronary angiographic finding the severity of the lesion is worse. the incidence of PCI or CABG of patients with chronic renal failure is more than that of control group but statistically no difference between patients with chronic renal failure and control group. the sex, the duration of disease, the duration of dialysis, serum creatinine in patients with chronic renal failure have no correlation to the prevalence of coronary artery disease and severity of lesion. hyperglycemic patients with chronic renal failure have high incidence of coronary artery disease and are worse in the severity of lesion Conclusions : There is significantly increased the pevalence and severity of involving multiple coronary artery diseses in hyperglycemic patients with CRF.

      • SCIESCOPUSKCI등재
      • 말초혈액에서 Tg mRNA에 대한 역전사 중합효소 연쇄 반응법의 갑상선 재발암의 분자생물학적 진단

        권성일,박기룡,김현영,신채희,임영찬,최영식,박요한,이강대,장희경,이재화,염하용 대한내분비학회 2002 Endocrinology and metabolism Vol.17 No.4

        연구배경: 갑상선암은 다른 조직에 발생한 암에 비해 비교적 천천히 자라므로 대부분 예후가 양호하지만, 일부에서는 주위 조직으로 침윤하거나 혹은 원격 전이로 인하여 치명적인 결과를 초래할 수 있다. 갑상선전절제술 및 131^I 제거술 후 경과 관찰시 갑상선암의 재발과 전이의 진단에 있어 131^I 스캔과 혈청 Tg의 측정이 현재 임상에서 가장 많이 이용되고 있으나 이 방법에는 여러 가지의 결점이 있다. 최근 Tg mRNA에 대한 RT-PCR법을 이용한 여러 연구결과는 131^I 스캔과 혈청 Tg 측정의 결점을 보완할 수 있는 좋은 보조적인 진단법으로 이용할 수 있을 가능성을 제시하였다. 이에 말초혈액에서 측정한 Tg mRNA에 대한 RT-PCR법이 갑상선 절제술 및 방사성요드 치료 후 갑상선암의 재발 및 전이 유무의 진단에 유용한가를 알아보고자 이 연구 시행하였다. 방법: 분화된 갑상선암으로 진단된 후 갑상선전절제술을 시행받고 방사성요드 치료를 받은 환자 중 현재까지 한차례에 이상 추적 방사성요드 전신 스캔을 시행하고 추적관찰이 가능했던 유두선암 35예, 여포선암 5예를 대상으로 연구를 시행하였다. 대상군은 131^I 스캔 소견상 음성인 군(Group Ⅰ), 잔여조직이 있는 군(Group Ⅱ), 국소전이가 있는 군(Group Ⅲ), 및 원격전이 군(Group Ⅳ)으로 구분하였다. 정상 대조군은 갑상선질환이 없는 10예의 건강인으로 하였다. 대상환자의 말초혈액을 이용한 Tg mRNA에 대해 특이적인 primer를 이용하여 RT-PCR 및 nested RT-PCR을 시행하였다. 결과: 본 연구 결과는 다음과 같다. 1) 131^I 스캔 소견상 음성인 군 21예 중 1예에서 Tg가 양성소견을 보였다. Anti Tg Ab가 양성인 4예 모두 Tg가 음성을 보였다. 잔여조직이 있거나 국소전이 및 원격전이를 보인 군 19예 중 Tg가 양성인 경우는 4예였으나, Tg mRNA는 전예에서 양성이었다. 2) 131^I 스캔에서 국소 및 원격전이 소견을 보인 8예 중 4예에서 Tg가 음성으로 131^I 스캔과 혈청 Tg 사이에 불일치 소견을 보였다. 3) 말초혈액에서 특이적인 primer를 이용하여 RT-PCR 및 nested RT-PCR을 시행한 결과 대상군 40예 및 정상 대조군 10예 모두에서 Tg mRNA가 양성을 보였다. 결론: 본 연구에서 갑상선 절제술 및 방사성요드 치료 후 갑상선암의 재발 및 전이 유무를 평가함에 있어 역전사 중합효소 연쇄 반응법을 이용한 Tg mRNA 측정의 의의는 재평가되어야 한다고 생각된다. Background: Differentiated thyroid cancer is the most common endocrine malignancy. Despite advances in the treatment of thyroid cancer, disease recurrence and metastasis may occur in as many as 20% of patients, and so continues to pose major problems in its clinical management. Serum thyroglobulin (Tg) measurements, by immunoassay, are used to detect residual or recurrent thyroid cancer following thyriod ablation. However, the usefulness of immunoassay is limited by both the requirement for thyroid hormone withdrawal, to attain optimal test sensitivity, and interference by the antithyroglobulin antibody (Anti-Tg Ab). Recent studies have reported the clinical usefulness of reverse transcription-polymerase chain reaction (RT-PCR) detection of Tg mRNA in the peripheral blood of patients with differentiated thyroid carcinomas. We performed this study to evaluated the usefulness RT-PCR of Tg mRNA in peripheral blood of patients with thyroid carcinoma following a total thyroidectomy and radioiodine ablation therapy. Methods: Forty cases that underwent a total thyroidectomy and radioiodine ablation therapy were included in this study. Of the 40 patients, 35 were papillary carcinomas and 5 were follicular carcinomas. Ten normal control subjects were also studied. Tg mRNA was extracted. Then RT-PCR and nested RT-PCR, were run with specific Tg primers. Concurrently, DNA sequencing of the isolates was carried out to prove the isolates were identical to the nucleotide sequence of the Tg. Results: The Tg was detected in 4 of 19 patients, with either a residual thyroid bed, or metastasis, on a 131^I whole body scan and in 1 of 21 patients with a negative radioiodine scan. Surprisingly, the Tg mRNA was detected in all the patients and normal controls. Conclusion: From our results we can not recommend Tg mRNA, detected by RT-PCR in peripheral blood, as a tumor marker superior to that of the Tg serum level. We consider an intensive re-evaluation of the method is required before considering its clinical applications (J Kor Soc Endocrinol 17:501∼513, 2002).

      • All-carbon-based cathode for a true high-energy-density Li-O<sub>2</sub> battery

        Lim, Hee-Dae,Yun, Young Soo,Cho, Se Youn,Park, Kyu-Young,Song, Min Yeong,Jin, Hyoung-Joon,Kang, Kisuk Elsevier 2017 Carbon Vol.114 No.-

        <P>Li-O-2 batteries have a high theoretical energy density; however, their current cathode system based on a heavy metal framework strikingly diminishes their real energy density. Herein, we report the fabrication of all-carbon-based cathodes composed of conventional active carbon and a carbon mesh (CM) framework produced from waste silk fabric by simple pyrolysis. CM frameworks show a high electrical conductivity of similar to 150 S cm(-1), good tensile strength of 34.1 +/- 5.2 MPa, and a Young's modulus of 4.03 +/- 0.7 GPa, as well as a well-ventilated ordered macroporous structure. These all-carbon-based cathodes exhibit stable cycling and high energy densities of similar to 2600 Wh kg(-1) based on total electrode weight, which are 4-15 times higher than those of conventional air cathodes. (C) 2016 Elsevier Ltd. All rights reserved.</P>

      • 남성화를 보이는 여성에서 발견된 난소의 Steroid Cell Tumor 1예

        조인호,정대훈,박영미,서영진,손영실,정철회,강영미,정수전,김영남,이경복,성문수,김기태 인제대학교 2006 仁濟醫學 Vol.27 No.-

        Steroid cell tumor is a rare ovarian sex cord-stromal tumor which accounts for 0.1% of all ovarian tumors. Until now, only 4 cases have been reported in domestic literatures. Steroid cell tumor often secrets testosterone and presents virilization in adult women or precocious puberty in children. Treatment is often performed by surgical removal, adjuvant chemotherapy and radiation, but completely accepted treatment was not existed. We experienced a case of steroid cell tumor, which was manifested by typical virilization in a 43-year old patient, who was previously performed hysterectomy and unilateral oophorectomy. So, we present with a brief review of the literatures.

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