개 비장 질환의 미세세침흡입술을 통한 세포병리학 검사 4례

김현아,윤기영,최호정,정성목,이영원,조성환,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2011 動物醫科學硏究誌 Vol.18 No.1

To evaluate the accuracy and diagnostic significance of cytopathological diagnosis of canine splenic disorders, cytopathological examination throgh fine-needle aspiration(FNA) referred to Veterinary Medical Teaching Hospital of Chungnam National University were retrospectived. Splenic neoplasm, hemolymphatic neoplasm, hyperplasia, extramedullary hematopoiesis and splenitis were diagnosed canine splenic disorders through cytopathological examination. The patient should be identified what coagulation profile are normal before aspiration, because complication such as hemorrhage could happen. The 4 cases were identified symmetric, asymmetric splenomegaly on abdominal ultrasonography and then were performed ultrasound-guided FNA. The 4 cases were diagnosed hemangiosarcoma(2), hyperplasia(1) and extramedullary hematopoiesis(1) by clinical signs, hematological examination, and cytopathological examination. Cytopathological examination through FNA was cost-effective, no gneral anesthesia, no complication, and non-invasive method of diagnosis for canine splenic disorders.

2세 영아가 놀이과정에서 경험하는 갈등에 관한 문화기술적 연구

조영아,김수영 大邱大學校 師範大學 附設 敎育硏究所 2010 學校敎育硏究 Vol.6 No.1

본 연구는 2세 영아들이 놀이과정에서 경험하는 갈등 양상과 갈등해결전략을 참여관찰(participant observation)을 통해 살펴보았다. 본 연구에 의하면 놀이 과정에서 또래와 경험하는 갈등 요인은 크게 6 가지로 제한된 놀잇감의 수, 완성된 구성물 방해, 놀잇감 뺏기, 놀이 영역, 놀이 탐색 및 놀이 참여 과정, 상징부여과정에서 갈등이 유발되었다. 갈등상황에서 영아들의 갈등해결전략은 친구에게 일러주기, 교사에게 일러주기, 되돌려주기, 거절하기, 망가뜨리기, 언어적 공격하기, 함께하기, 칭찬하기, 교사 부르기, 요구하기, 다른 또래의 도움, 거부하기, 부정하기, 사과하기, 놀리기, 회피하기, 신체적 공격하기, 설명하기, 대안제시하기, 부탁하기, 인정하기, 무시하기, 제안하기, 수용하기 등 총 24가지 유형으로 관찰되었다. This study examines the aspect of conflict that 2 year infants face through playing and strategy of solving the conflict through the participant observation. According to this study, factors of conflict experiencing through playing with the same age group are largely six factors; the limited number of toys, disturbance of finished components, taking toys away, playing area, exploring play and process of participating into the play, process of granting symbols, and from these processes conflicts are occurred. It is examined that in the situation of the conflict, there are 21 types of infant's strategy to solve the conflicts; telling their friends, telling their teacher, returning, rejecting, breaking, verbal attacking, being together, praising, calling the teacher, demanding, help from others who are the same age, denying, apologizing, teasing, avoiding, physical attacking, explaining, proposing alternatives, favouring, admitting, ignoring, suggesting, accepting, etc.

당귀의 품질평가법에 관한 연구

조창희,김수정,이남윤,우영아,김효진 동덕여자대학교 종합약학연구소 2001 동덕약학연구지 Vol.5 No.-

Angelicae gigantis radix is the root of the perennial plant, which belongs to family Umbelliferae. However, this herbal drug has quite different chemical components according to its different geographical origin though other herbal drugs (i.e. Leonuri Herba, Xanthii Fructus and so on) show similar major constituents. In other word, the root of Angelica gigas containing the coumarin compounds is commonly used in Korea as Angelicae gigantis radix, while Angelica sinensis and Angelica acutiloba including phthalide compounds are used in China and Japan, respectively. In this paper, Near-Infrared spectroscopy was developed to determine Genus name of Angelica spp., especially Angelica gigas and Angelica sinensis which are generally misused in the herbal market. Also X-ray fluorescence spectrometry was evaluated to analyze the differences between Angelica gigas and Angelica sinensis with their specific properties.

대황황련해독탕의 사염화탄소 유발 간장해 보호효과 미치 급성독성

김영석,정은아,장종철,양형길,김남재,조기호,배형섭,이경섭,김동현 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2002 東西醫學硏究所 論文集 Vol.2002 No.-

ABSTRACT - This study was performed to evaluate hepatoprotective effect of daewhang-whangryunhaedok-Tang(DWT) on liver injured rats induced by CCI_4 and the acute oral toxicity of it in mice. The activities of serum transaminase(ALT/AST), alkaline phosphatase(ALP) and lactic dehydrogenase(LDH), the levels of serum total cholesterol(TC) and triglyceride(TG), change of liver enlargement, and inhibitory activities of lipid perotidation, catalase and glutathione-S-transfrease(GST) in liver microsome were determined in hepatotoxic rats induced by CCI_4. DWT was significantly reduced the serum ALT, AST, ALP, LDH. TC and TG lecels. And, the increase of lipid peroxidation, decrease of catalase and GST activities in the liver microsome of CCI_4-intoxicated rat were significantly improved by the treatment of DWT. Male and female mice were administered maximum dosages of 5.000 mg/kg b.w. of DWT. After single oral administration of DWT to mice, we observed them daily for 2 weeks.DWT did not induce any toxic signs in the mortalitie, clinical signs, body weight changes, and gross necropsy finfings of mice. Based in these results. It is concluded that DWT may have the hepatoprotective effect on CCI_4 induced hepatotoxicity in rats. Also. DWT may have no side effect and its LD_50 value may be over 5.000mg/kg b.w. in mice.

교사 학습공동체 내 지식창출 활동의 성격 및 촉진요인에 대한 사례 연구

주영주,조은아 이화여자대학교 사범대학 교과교육연구소 2006 교과교육학연구 Vol.10 No.1

지식기반사회를 맞아 지식과 학습의 관계에 대한 다양한 논의가 이루어지고 있는데, 그 중 사람들간의 협력적 관계나 실제 활동을 통해 생산되는 역동적 지식의 창출과 공유를 위해 현재 활발하게 시도되고 있는 학습방법 및 지식관리전략 중 하나가 학습공동체라 할 수 있다. 기업의 지식경영 영역에서 뿐만 아니라, 교육현장에서의 새로운 전문성과 경쟁력을 제고하는 방법으로서도 학습공동체를 통한 지식창출이 중요한 이슈가 되고 있다. 학습공동체에 대한 논의는 이미 교육현장에서부터 시작되어 왔으나, 그 실행에 있어 교육청의 행정적 관여로 인해 교사들의 자발적 참여가 확신되지 못했고, 교사들의 요구를 충족시키지 못했다는 문제점들이 있었다. 이에 본 연구는 문화관광부의 지원대상이 되며 문화예술분야의 교사들을 대상으로 구축된 학습공동체인 '교사자율연구모임'의 사례를 통해, 교사 학습공동체의 유형과 공동체 내에서 이루어지는 지식창출 활동의 성격을 분석하고, 교사의 지식창출 환경으로서의 학습공동체 촉진요인을 도출해 보고자 하였다. '교사자율연구모임'을 분석한 결과, 동 학습공동체는 동일 분야의 동료 교사들과 상호협력적 학습을 통해 지식을 공유함으로써 교사로서의 자신의 전문성을 개발하는 것이 주요 목적인 전문성을 위한 학습 공동체로 파악되었다. 또한 학습공동체들은 대부분 연구와 현장활동을 병행하고 있었다. 교사자율연구 모임 내에서 습득, 공유되는 지식과 경험은 주로 교육콘텐츠의 제작 및 창작 활동, 연구 및 이론 개발, 공동의 문제해결을 위한 학습으로서의 연수활동 등이었다. 교사자율연구모임을 활성화시키기 위해 공동체로서의 목표공유, 참여에 대한 자발성, 동료의식 등 사회적 요인 등이 주요 촉진 요인으로 도출되었다. 특히 공동체 의식, 동료의식 등 정의적 영역의 요인들이 교과연구를 통한 인지적 성과달성에 비해 실제 교사 학습공동체의 지식창출 및 공유활동을 촉진시키는 요인으로 도출되었다. Learning Community is the learning method and knowledge management strategy which is actively attempted of collaborative learning and creation and sharing of knowledge being produced in authentic context. Knowledge creation through Learning Community has become an important issue not only in the fi디d knowledge management, but also in the educational field. Many studies on Learning Community have already begun in the field of education. But, there has been some obstacles to voluntary participation of teachers due to administrative intervention of educational offices. Accordingly, this study tries to analyze the type of teachers' Learning Community and the characteristics of knowledge-creating activities occurring in Learning Community, and to discover promotive elements of Learning Community as teachers' knowledge-creating environment, by example of "Teachers' Voluntary Research Group", which is a Learning Community aimed at teachers in the field of arts and culture, supported by the Ministry of Culture and Tourism. After analyzing the "Teachers' Voluntary Research Group", I concluded; the group was considered as a Learning Community aimed at developing their competency as teachers, by sharing knowledge through collaborative learning with colleagues belonged to the same field. Also, most of communities conducted researched and practices at the same time. The main knowledge and experience being acquired and shared in the "Teachers' Voluntary Research Group" was production of educational contents, research and developing theory and collaborative learning for problem-solving. Major promotive elements of the "Teachers' Voluntary Research Group" were social elements such as joint enterprise of community, voluntary participation and sense of colleagues. Especially, the sense of community and the sense of colleagues were indicated as more effective elements to promote knowledge creation and sharing of teachers' learning community, rather than cognitive ones.

e-Learning 내 지식창출(Knowledge Creation)을 위한 가상적인 바(Cyber-Ba)에 대한 고찰

주영주,조은아 이화여자대학교 사범대학 교과교육연구소 2006 교과교육학연구 Vol.10 No.1

지식관리시스템은 최근 e-Learning의 도입을 통해 조직 내 지식경영과 학습체계를 결합시키는 효율적이면서 효과적인 방향을 모색하고 있다. 특히 e-Learning은 다양한 정보기술 도구를 바탕으로 사이버 공간에서의 학습의 효과를 극대화시키는 것이 목표이며, 이를 지식경영의 측면에서 본다면 e-Learning은 조직이 사이버 공간 내에서 지식을 창출하게 하는 도구이자 시스템이 된다는 뜻이다. 그러므로 과연 정보기술을 통한 학습도구로서의 e-Learning이 조직의 지식 창출이라는 새로운 요구에 대해 어느 정도 도움을 줄 수 있는지를 알아보는 것은 앞으로 e-Learning과 지식경영을 통합시키고자 하는 노력에 있어 필수 과제라 생각된다. 이를 위해 우선 조직에서의 지식창출의 과정과 지식창출의 장으로서의 바와 관련된 노나카의 이론을 살펴보고, e-Learning에 있어 지식창출과 학습의 관계를 규명하고자 하였다. 또한 지식창출의 사회화, 외재화, 종합화, 내재화의 4가지 사이클 별로 어떠한 정보기술이 현재 상태에서 e-Learning상에서의 지식창출에 있어 지원 가능한지에 대해서 관련된 문헌을 고찰하였다. 조직 내에서의 지식창출 및 공유를 위해서는 가치있는 지식을 창조하는 활동을 학습이 지원하며, e-Learning은 그러한 의미의 진정한 학습이 이루어짐으로써 지식이 창출되는 환경이 되어야 한다. e-Learning 내에서 활용되는 정보기술은 지식창출의 과정별로 근본적인 바, 상호적인 바, 가상적인 바, 학습의 바 등 각각 가상적인 바를 형성함으로써 e-Learning을 통한 지식창출을 지원하게 되는 것이다. 즉 e-Learning 내에서 형성되는 가상적인 바가 지식창출의 네 가지 사이클을 모두 지원할 수 있다는 관점에서 e-Learning과 지식창출의 연계성이 의미를 가진다 하겠다. By introducing e-Learning, knowledge management system is seeking efficient and effective methods to combine knowledge and learning in organizations. Based on various informational technology, e-Learning aims at maximizing effect of learning in cyber space. In terms of informational technology, e-Learning is a tool and a system that enables organizations to create knowledge in cyber space. Therefore, it is essential to integrate e-Learning and knowledge management that how much e-Learning, as a learning method through informational technology, can help organizational knowledge creation. For this purpose, first, the article examined Nonaka's theory, the process of knowledge creation in organization, which is related to Cyber-Ba as a place of knowledge creation. The article also examined some related treatises on which informational technology is currently able to assist knowledge creation on e-Learning by four of each cycle; socialization, externalization, combination and internalization. For knowledge creation and sharing in organization, the activities to creating valuable knowledge should be assisted by learning, and e-Learning should be a knowledge-creating environment by achieving and authentic learning. Informational technology used in e-Learning, by forming each Cyber-Ba such as Originating Ba, Interacting Ba, Cyber Ba and Exercising Ba in the process of knowledge creation, will assist knowledge creation in e-Learning, In other words, from a viewpoint that Cyber-Ba which is formed in e-Learning can assist all the four cycle of knowledge creation.

대황황련해독탕의 항고지혈증 작용

김영석,정은아,장종철,양형길,김남재,조기호,배형섭,이경섭,김동현 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2001 No.-

Whangryunhaedok-Tang (WT) is formulated with Coptidis Rhizoma, Phellodendri Cortex, Scutellariae Radix and Gardeniae Fructus, and Daewhang-whangryunhaedok-Tang (DWT) is made by the combination of Rhei Rhizoma, a wellknown anticostipation drug in WT. Therefore, DWT has been evaluated for antihyperlipidemic effects on experimental hyperlipidemic rats and mice induced by corn oil and high cholesterol-diet. Oral administration of DWT significantly inhibited the increase of serum triglyceride and LDL-cholesterol levels, and the decrease of serum HDL-cholesterol levels in hyperlipidemic rats induced by corn oil. Also, oral administration of DWT significantly prevented the increase of serum total cholesterol, triglyceride and LDL-cholesterol, and liver total cholesterol and triglyceride in 1% cholesterol-diet fed mice. These results suggest that DWT is effective for the treatment of hyperlipidemia.

브라켓 부착 시 실런트 레진이 법랑질 탈회에 미치는 영향

윤영아,조진형,이기헌 대한치과교정학회 2005 대한치과교정학회지 Vol.35 No.1

본 연구는 교정용 브라켓 부착 시 사용되는 접착제 중 two paste type 의 실런트 레진 적용이 법랑질 탈회에 미치는 영향을 알아보고자 시행되었다. 건전한 표면을 가진 발치된 소의 상악절치 48개를 실험재료로 하여 법랑질 처리 방법에 따라 4개 군으로 분류하고 각 군을 Phase Ⅱ^(?) (Reliance, Itasca, Ⅲ) 를 이용하여 치면처리 하였다. 대조군으로서 아무런 처리를 하지 않은 Group 1, 37% 인산으로 39초간 산부식을 시행한 Group 2, 산부식 후 실런트 A와 B를 동량으로 혼합하여 도포한 Group 3과 산부식 후 실런트를 도포하고 레진 페이스트 A와 B를 동량으로 혼합하여 도포한 Group 4로 분류하여 각 군을 인공탈회용액에서 탈회시킨 다음 공초점 레이저 주사현미경을 이용하여 각각의 탈회된 깊이를 측정한 후 비교한 결과, 탈회된 법랑질의 평균 깊이는 47.4 ㎛ (Group 1), 61.8 ㎛ (Group 2), 13.9 ㎛ (Group 3), 8.2 ㎛ (Group 4) 로 나타났다. 산부식 후 인공탈회용액에 노출되는 군(Group 2)은 산부식 없이 노출되는 군 (Group 1) 에 비해 탈회된 깊이가 더 깊은 것으로 나타났으며 (p <0.55), 실런트 레진을 도포한 군 (Group 3) 은 산부식 없이 노출되는 군 (Group 1) 이나 산부식 후 노출되는 군 (Group 2) 에 비해 탈회된 법랑질 깊이가 유의성 있게 감소하였다 (p <0.55). 접착레진으로 부착된 군 (Group 4) 은 법랑질 탈회가 거의 나타나지 않았다. 이상의 연구결과는 교정지료 시 법랑질 탈회 가능성을 줄이기 위해서 브라켓 부착 시 실런트 레진의 도포가 유용함을 시사하였다. The purpose of this study was to evaluate the effects of a sealant resin on enamel demineralization in orthodontic bracket bonding. The forty eight extracted sound bovine teeth were subdivided into four groups and treated with Phase Ⅱ^(?) (Reliance, Itasca, Ⅲ) on the surface. Group 1 was not treated. Group 2 was acid etched with 37% phosphoric acid for 30 seconds. Group 3 was applied with sealant after acid etching. Group 4 was applied with resin paste after acid etching and sealant application. Each group was demineralized in artificial caries solution. Demineralized enamel depth was measured by confocal laser scanning microscopy. The results were as follows: the mean demineralized enamel depth was 47.4 ㎛ (Group 1), 61.8 ㎛ (Group 2), 13.9 ㎛ (Group 3), 8.2 ㎛ (Group 4) the demineralized enamel depth was increased in Group 2 than in Group 1 (p < 0.05) the demineralized enamel depth was reduced in Group 3 than in Group1 and Group 2 with statistically significant differences (p < 0.05) and demineralization in Group 4 was very little. The results of the present study indicate that sealant application is useful for reducing enamel demineralization in orthodontic bracket bonding.

근적외 분광 분석법을 이용한 사향 대체 물질별 우황청심원액의 분류

김선민,우영아,김효진,조창희,조정희 동덕여자대학교 종합약학연구소 2005 동덕약학연구지 Vol.9 No.-

The object of this study is to develop a nondestructive and rapid analytical method to classify WooHwangChongShimWon solution according to the types of musk substitutes such as L-muscone, civet, camphor, etc. Its indications are apoplexy, hypertension, palpitation, convulsions and unconsciousness. Musk was one of major components for WooHwangChongShimWon in the traditional prescription which is secreted by the glands of the male Moschus moschiferus parvipes. Because the use of musk is prohibited for the animal protection by the Convention on International Trade in Endangered Species of wild Fauna and Flora(CITES), manufacturing companies are using various type of substitutes for musk for musk in the recent. The quality and price of the musk substitutes will be different. However, there have been difficulties to classify of different products from different companies base on the substitutes. In this study, Near infrared spectroscopy was used for the development of classification methods. Seven different samples depending the substitutes from five pharmaceutical companies were used as samples and Near infrared(NIR) transmittance spectra were collected over the region 1100 to 1750nm. Even though spectral features based on the substitutes were not different, NIR spectral data of samples were clearly classified using principal component analysis(PCA). The proper conditions for sample preparation and measurement of spectral data were investigated; sampling preparation such as clear supenatant samples after centrifugation and uniformly suspended samples were compared and the comparison of water and air as reference materials were performed when acquring spectral data. In the PCA, the optima PC numbers were also investigated for classification condition. Overall, NIR transmittance spectroscopy using PCA was shown to have significant potential as a rapid method for classification of WooHwangChongShimWon solution based on musk substitutes.

한국구강보건사업이 초등학교 아동들의 유치 및 영구치 우식실태에 미치는 영향

최순례,유영아,조민정,송근배 韓國學校保健學會 2004 韓國學校保健學會誌 Vol.17 No.2

Purpose : The aim of this study was to evaluate the effects of oral health care programs in a school-based oral health care center among primary schoolchildren. Methods : School-based oral health care programs included fluoride mouth rinsing, pit and fissure sealing for permanent premolars and molars, fluoride gel application and chewing of xylitol candy. All of the programs were carried out by one dental hygienist among 'D' primary schoolchildren in Daegu city under the supervision of a dentist. Baseline dental examinations were completed and preventive care was implemented for 544 children during one year. All of the children visited a school-based oral health care center every three months for a regular check-up. The final oral examination was conducted from March 15 to April 1, 2004. The data analysis data was made on the basis of SAS 8.01. Mean differences between 2003 and 2004 data were compared by paired t-test. Corresponding p-values were considered significant at values less than 0.05. Results : The DMF rate and DFT index were reduced to 8.0% and 8.4% during one year respectively, but there were no statistically significant differences. The DMF rate was significantly reduced (16.3%) after a one year program of school-based oral health care practice. The DMFT(Decay Missing Filling Tooth) index was also reduced compared to 2003 throughout the entire grade. Conclusion : School-based oral health care programs can reduce the prevalence of dental caries prevalence among schoolchildren during one year. This program also improved the oral health capacity of schoolchildren. It is recommend that the school-based oral health care program should be extended to every primary school in Korea