한국인 폐확산능 정상예측식의 임상적 유용성과 정확성

나승원 ( Seung Won Ra ),박태선 ( Tai Sun Park ),홍윤기 ( Yoon Ki Hong ),홍상범 ( Sang Bum Hong ),심태선 ( Tae Sun Shim ),임채만 ( Chae Man Lim ),이상도 ( Sang Do Lee ),고윤석 ( Youn Suck Koh ),김우성 ( Woo Sung Kim ),김동순 ( Dong 대한결핵 및 호흡기학회 2008 Tuberculosis and Respiratory Diseases Vol.64 No.2

연구배경: 폐확산능을 해석하는 데 필요한 정상예측식으로는 한국인을 대상으로 하여 박 등이 개발한 식(박 식)이 있으나 아직 외국 정상예측식을 많이 사용하고 있다. 이에 국내에서 많이 사용하는 외국 정상예측식인 Burrows 식과 박 식의 임상적 유용성과 정확성을 비교하고자 하였다. 방법: 1. 임상적 유용성 연구; 2006년 7월부터 12월까지 6개월간 폐확산능검사를 시행한 환자 중 두 식을 각각 정상예측식으로 적용하였을 때 폐확산능 해석이 다른 276명(대상군 A)을 대상으로 하였다. 대상군 A에게 두 식을 각각 적용하였을 때 폐확산능 해석과 임상적 판단과의 일치도를 비교하여 임상적 유용성을 평가하였다. 2. 간질성폐질환 진단의 정확성 비교; 2001년부터 2006년까지 폐조직검사를 시행하여 확진된 간질성폐질환군과 서울아산병원에서 모집한 정상군을 대상으로 하여 정상예측식으로 두 식을 각각 적용하였을 때 폐확산능 해석의 정확도를 비교하였고, 두 식이 차이가 나는지 맥니머의 카이스퀘어 검정을 하였다. 결과: 1. 임상적 판단과의 일치도 비교; 276명을 임상정보를 토대로 폐확산능을 예측하여 분류한 결과 정상 54명, 감소 220명, 불분명이 2명이었다. 예측식으로 박 식과 Burrows 식을 적용하였을 때 임상적 판단과 일치하는 환자는 각각 78%와 22%이었다(p<0.001). 2. 간질성폐질환 진단의 정확성 비교; 박 식은 민감도 90.1%, 특이도 100%이었고 Burrows 식은 민감도 64.2%, 특이도 100%로 민감도가 통계학적으로 유의하게 박 식이 높았다(p<0.001). 결론: 우리나라 정상예측식인 박 식이 외국 정상예측식인 Burrows 식을 정상예측식으로 적용하는 것보다 임상적 유용성이나 간질성폐질환 진단의 민감도에서 더 우월하였다. 향후 폐확산능검사의 정상예측식으로 박 식을 사용해야 할 것으로 사료된다. Background: Park et al. developed the Korean reference equation for the measurement of diffusing capacity in 1985. However, the equation has not been widely used in Korea and foreign reference equations have been popularly used. We intended to compare the clinical usefulness and the accuracy of the the Korean reference equation (Park`s equation) with that of the foreign equation (Burrows` equation) that is commonly used in Korea. Methods: 1. Evaluation of clinical usefulness; Among 1,584 patients who underwent diffusing capacity (DLCO) at the Asan Medical Center from July to December 2006, group A subjects included 276 patients who had different interpretations of DLCO in trials employing Burrows` equation and Park`s equation. Clinical assessment was decided by consensus of two respiratory physicians. In order to evaluate the clinical usefulness of Burrows` equation and Park`s equation, agreement of clinical assessment and DLCO interpretation were measured. 2. Evaluation of accuracy; Group B subjects were 81 patients with interstitial lung disease (ILD) and 39 normal subjects. The 81 ILD patients were diagnosed following a surgical lung biopsy. The accuracy of diagnosing ILD as well as sensitivity and specificity were evaluated according to the use of the reference equations (Burrows` equation and Park`s equation) for DLCO. Results: Agreement between clinical assessment and interpretation of DLCO was 22% for the use of Burrows` equation and 78% for the use of Park`s equation. The sensitivity and specificity of the Burrows` equation for diagnosing ILD were 64.2% and 100%. The sensitivity and specificity of the Park`s equation for diagnosing ILD were 90.1% and 100%. The sensitivity of the Park`s equation for diagnosing ILD was significantly higher than that of Burrows` equation (p<0.001). Conclusion: The Korean reference equation (Park`s equation) was more clinically useful and had higher sensitivity for diagnosing ILD than the foreign reference equation (Burrows` equation). (Tuberc Respir Dis 2008;64:80-86)

한국인에서 일광 노출의 유해성에 대한 인지도와 일광 차단제의 이용 행태에 대한 연구

김상태,김기호,오선진,이승철,강세훈,윤재일,김진준,박석범,김홍용 대한피부과학회 1999 大韓皮膚科學會誌 Vol.37 No.6

Background: Although deleterious effects of sunlight have been increased recently, the surveillance of the attitudes toward sun-exposure and the behavioral aspect of using sunscreens in Koreans has hot been carried out. Objective: Our purpose was to evaluate the attitude toward the harmfulness of sun-exposure and behaviors of using sunscreens in Korea. Method: Five hundred and fifty-two subjects were surveyed to assess the attitude toward sun-exposure, as well as the subjects knowledge about, and the use of sunscreens. Underlying data including demographic data, skin colors, skin types, occupation, and sun-exposure, were obtained. Results: Fifty-four percent of subjects believed that sun-exposure is bad for their skins, but, on the contrary, 12.5% believed it to be beneficial. Fifty-two percent of subjects used sunscreens. Almost all subjects(93.8%) knew why to use sunscreens but 62.7% of subjects did not know the meaning of sun protective factors(SPF). Women, indoor workers, subjects less than 40 years old, with less sun-exposed, fair colored skin, or with skin type I, II, III tended to know the deleterious effects of sunlight and the meaning of SPF and used more sunscreen. Conclusion: High risk population-men, outdoor workers, subjects oider than 40 years old, with more sun-exposed, dark colored skin, or skin type VI, V could be targeted with campaigns that promote attitudinal and behavioral changes.

변색 실활치에 대한 carbamide peroxide gel의 표백효과

박선아,김선호,황윤찬,오병주,윤창,박영준,정선와,황인남,오원만 大韓齒科保存學會 2002 Restorative Dentistry & Endodontics Vol.27 No.4

The bleaching of discolored nonvital teeth is conservative treatement that satisfy the cosmetic desire. The most common method for this treatement, walking bleaching, is using 30% hydrogen peroxide and sodium perborate. Many alternatives are suggested for preventing the external cervical root resorption that is the common complication of the nonvital teeth bleaching with 30% hydrogen peroxide. The same extent of oxidation reactions as that resulted by the bleaching with the application of 30% hydrogen peroxide and sodium perborate can also be acquired more safely by materials that contain 10% carbamide peroxide, used primarily for the bleaching of vital teeth. Therefore, this study was performed to evaluate the efficacy of 10% and 15% carbamide peroxide bleaching gel in nonvatal teeth bleaching. The internal bleaching of intentionally discolored teeth was performed in vitro with 10% carbamide peroxide (Group 1), 15% carbamide peroxide (Group 2), mixture of distilled water and sodium perborate (Group 3), and mixture of 30% hydrogen peroxide and sodium perborate (Group 4). The bleaching materials were refreshed following 3, 6, 9 and 12 days. To evaluate the bleaching effect, the color change of the crowns was measured at 1, 2, 3, 4, 7 and 15 days of bleaching using the colorimeter. The results were as follows : 1. L^* and ΔE^* values were increased with time in all bleaching agents(p<0.01). 2. There was no significant difference in L^* and ΔE^* value among bleaching agents. 3. Δ^* value higher than 3 was shown after 3 days of bleaching with 10% carbamide peroxide gel, 1 day with 15% carbamide peroxide gel, 4 days with mixture sodium perborate and distilled water and 4 days with mixture sodium perborate and 30% hydrogen peroxide, respectively. These results revealed that the use of 10% and 15% carbamide peroxide bleaching gel in non-vital teeth bleaching is as effective as mixture of distilled water and sodium perborate and mixture of 30% hydrogen peroxide and sodium perborate. Accordingly, carbamide peroxide could be used clinically to bleach discolored non-vital teeth.

부모양육태도와 자존감이 학교폭력 가해행동에 미치는 영향 특성화 고등학교를 중심으로 -

박선주 ( Park Sun Joo ),조휘연 ( Cho Hui Youn ),황선정 ( Whang Sun Jung ) 한국사회복지경영학회 2019 사회복지경영연구 Vol.6 No.1

본 연구의 주된 목적은 학교폭력 가해 경험이 있는 특성화 고등학교 학생들의 부모 양육태도가 학교폭력 가해 행동에 미치는 영향과, 자존감이 학교폭력 가해행동에 미치는 영향, 부모의 양육태도가 자존감에 미치는 영향 및 학생들의 학교폭력에 대한 인식을 분석하는데 있다. 연구대상은 총 122명으로 학교폭력 가해 경험이 있는 특성화 고등학교 남학생과 여 학생(남자 101명 여자 21명)이었다. 측정도구로는 부모양육태도와 배경정보에 대한 것은 Barber(1997)의 척도를 토대로 문항을 재구성하여 다시 제작한 김해영(2000)의 척도와, 자존감 측정도구로는 Rosenberg(1965)의 자존감 척도를 이춘진, 원호택 (1995)이 번안한 한국판 척도를 사용하였고, 학교폭력 가해 경험은 김준호, 김선애(2003)가 개발하고 김언지 (2004)가 수정 보완한 학교폭력 경험 측정도구 중 가해경험 문항을 사용하였으며, 학교폭력에 관한 인식은 김범수(2009)의 설문을 질적 문항으로 수정 보완하여 사용하였다. 분석 결과는 다음과 같다. 첫째, 부모의 양육태도가 학교폭력에 미치는 영향을 분석해 본 결과, 부모의 양육태도 중에 자율이 높아질수록 학교폭력은 낮아진다고 나타났다. 둘째, 부모의 양육태도가 자존감에 미치는 영향을 분석해 본 결과, 부모의 양육태도 중에 신뢰가 높아질수록 자존감이 높아진다고 나타났다. 셋째, 자존감이 학교폭력에 미치는 영향을 분석해 본 결과, 자존감은 학교폭력에 영향을 미치지 못하는 것으로 응답하였다. 넷째, 특성화 고등학교 학교폭력 가해 경험이 있는 학생들의 학교폭력에 대한 인식을 분석해 본 결과 학교폭력이 매우 심각하다고 가장 많이 응답하였으며, 보통, 미응답, 심각하다의 순으로 나타났다. 학교폭력의 주도적인 해결자로는 당사자가 가장 많은 응답을, 학교, 미응답, 경찰, 친구의 순으로 나타났다. The main purpose of this study is to analyze the impact of parenting behavior on school violence behavior of students of specialized high schools with experience in school violence, the impact of self-esteem on school violence behavior, the impact of parenting attitude on self-esteem, and the perception of school violence on students. A total of 122 students were subject to the study, with boys and girls from specialized high schools (101 men and 21 women) with experience in committing school violence. For measuring instruments, parents' adoptive attitudes and background information are based on Barber (1997), Kim Hae-young (2000) reconstructed and recreated based on Barber (1995), and Rosenberg (1965V s self-esteem measures were used by Lee Chun―jin and Won Ho―taek (1995),while Kim Sun-joon (1995) developed a Korean version of a school violence experience. The results of the analysis are as follows. First,after analyzing the impact of parental attitudes on school violence, it was found that the higher the self-esteem, the lower the school violence. Second, after analyzing the impact of parental attitudes on self-esteem, the higher the level of confidence among parents' attitudes, the higher the level of self-esteem. Third,after analyzing the impact of self-esteem on school violence, the results showed that self-esteem does not affect school violence. Fourth, after analyzing the perception of school violence by students with experience of committing school violence in specialized high schools,the school violence was most said to be very serious, in the order of normal,unresponsive and serious. As the leading solver of school violence, the parties responded the most,followed by schools,non-response, police and friends.

활동성 화농성 고관절염에 시행한 2단계 인공 고관절 치환술

박윤수,문영완,성기선 대한고관절학회 2003 Hip and Pelvis Vol.15 No.3

고구려의 불교 수용

박윤선 한국고대사학회 2004 韓國古代史硏究 Vol.35 No.-

The historical materials about the early stage of acceptance of Buddhism in Goguryeo, can be divided by two parts. One part is about the acceptance of Buddhism from Jeonjin in King Sosurim era and the propagation of Buddhism of Damsi. This part consists of the periodical materials of Jiban region which was the capital city of Goguryeo and Yodong region which was the path from North China to Jihan. The other part is about the mode of Buddhism at the Anak No 3 Tumulus, the tomb of Deokheung-ni and the existence of Goryeo ascetic(고려도인). Those tombs are situated at the downstream of Daedong river, which was the old territory of Nangrang and Deabang. In the analysis of those materials, it is highly possible that Goguryeo had already accepted Buddhism in the early 4th century. Also, the route of the national acceptance of Buddhism through the Northern states in China can be distinguished by the route of civilian acceptance which was influenced by the uniqueness of the old territory of Nangrang. The nature of these two Buddhism shows certain differences. The Buddhism from Hujo, Jeonyeon and Jeonjin consists of the pursuit of secular benefit and propagation by the super- natural power of monks, the political activities of higher monks, the stern practice of Vinaya(계율) and the prevalence or Prajnaparamita-sutra(반야경), white The Thought or Pure Land(정토사상)and Vimalakirti - sutra(유마힐경) were accepted and the Gyeokeui(格義) Buddhism was showed in the region of Daedong river. We can find the attitude of strict execution of Vinaya and the prevalence of Prajnaparamita - sutra, which is the bridge of Taoism, in Dongjin Buddhism as in the Northern states in China. Therefore, they would be included in Buddhism of Goguryeo. From the early era, Goguryeo accepted the two different trends of Buddhism from the both side of Southern and Northern Chinese states. At this early stage of the acceptance, Buddhism in Jiban region shows the inclination of the Northern states of China because of the national acceptance, while in the old territory of Nangrang Buddhism was accepted at the level of civilian, which was popular at Dongjin in China.

The Efficacy and Safety of 4-n-butylresorcinol 0.1% Cream for the Treatment of Melasma: A Randomized Controlled Split-face Trial

( Sun Young Huh ),( Jung Won Shin ),( Jung Im Na ),( Chang Hun Huh ),( Sang Woong Youn ),( Kyoung Chan Park ) 대한피부과학회 2010 Annals of Dermatology Vol.22 No.1

Background: Melasma is a common acquired symmetrical hypermelanosis that occurs on sun-exposed areas, and it is frequently observed among women. Various treatment modalities have been tried, but none are completely satisfactory. 4-n-butylresorcinol, which is a resorcinol derivative that has an inhibitory effect on both tyrosinase and tyrosinase-related protein-1, was introduced in 1995 and it has received increasing attention as a new hypopigmenting agent. However, the hypopigmenting effect of 4-n-butylresorcinol in human subjects has only been shown in a few studies. Objective: The aim of this study was to investigate the hypopigmenting efficacy and safety of 4-n-butylresorcinol 0.1% cream for the treatment of melasma. Methods: Twenty patients with melasma were enrolled to this randomized, double-blind, vehicle-controlled, split-face comparative study. The patients were instructed to apply 4-n-butylresorcinol 0.1% cream or vehicle to each side of the face twice daily for 8 weeks. Mexameter measurements were performed along with photography at baseline, 4 weeks and 8 weeks. Adverse events were observed and recorded throughout the study. Results: All the patients completed the study. Mexameter measurements demonstrated that the melanin index of the treated side showed a significant decrease when compared with that of the vehicle-treated side after 4 weeks (p=0.006) and after 8 weeks (p<0.0005). All the adverse reactions were mild and transient. Conclusion: 4-n-butylresorcinol 0.1% cream showed rapid efficacy and it was well tolerated when used for the treatment of melasma. (Ann Dermatol 22(1) 21∼25, 2010)

FAN용 외전형 BLDC전동기 설계 및 특성해석

윤선기,박영일,이광호,조윤현 東亞大學校 1999 東亞論叢 Vol.36 No.-

Permanent magnet brushless motors are increasingly being used in high performance applications. The advantage of using a BLDC motor is that is can be controlled to have the speed-torque characteristics similar to that of a permanent magnet DC motor. In addition, the BLDC motor has low ineria, large power to volume ratio, and low noise as compared with the permanent magnet DC servo motor having the same output rating. This paper is proposed the design method of Outer Roter BLDC for a blower fan by the magnetic equivalent method. In order to compute and estimate the performance parameter of Outer type BLDC, the dynamic model and charateristics analysis of BLDC is simulated by Matlab.

지르코늄 핵연료피복관의 부식에 미치는 내부압력의 영향

박정용,김선기,정용환,정연호 대한금속재료학회 2004 대한금속·재료학회지 Vol.42 No.1

Effect of the internal pressure on the corrosion behavior was investigated for the Zr nuclear fuel cladding tubes which were pressurized up to 2500 psi using Ar gas and corroded in steam of 1500 psi at 400℃. It was found that corrosion resistance of Zr fuel cladding tube was decreased with increasing the internal pressure although corrosion behavior at the early stage was similar irrespective of internal pressure. X-ray diffraction result on the oxide showed that crystal structure was not affected by the applied pressure of 2500 psi. SEM observation on the oxide surface revealed that a number of cracks elongated in axial direction were propagated from surface to interior in the case of 2500 psi. The degradation of corrosion resistance with internal pressure was attributable to the extensive cracking at the oxide surface, which is thought to be originated from the difference of ductility between Zr alloy and oxide when Zr fuel cladding tube was deformed due to the applied internal pressure. However, the increase of corrosion rate with internal pressure was shown to be relatively small. It was therefore suggested that the crack induced at the surface did not propagate to oxide layer in the vicinity of oxide/metal interface which is known to be protective to oxygen diffusion and to control the corrosion behavior.

Fe-Sn系 燒結合金의 諸性質에 미치는 成形 및 燒結條件의 影響

박창선,김윤채 조선대학교 생산기술연구소 1998 生産技術硏究 Vol.20 No.1

Effects of compacting and sintering conditions on the properties of iron-tin sintered alloy for porous bearings were investigated in comparsion with those of iron compact. The results obtained are as follows. 1. The effect of compacting condition : When the green porosity becomes higher, the compact shrinks considerably but on the contrary. the pore-structure grows much more and the strength decreases largely. Therefore, in order to take the sintered compact having over 18vol% of the intercommunicating porosity and over 17kgf/㎟ of the radial crushing strength which are prescribed values for the sintered iron compact in JISB1581, the green porosity must be kept within 18~30% at the compacting. 2. The effect of sintering condition : When the sintering temperature becomes higher, the compact shrinks considerably but the pore-structure does not almost changed. On the other hand, the strength increases much more. And when the keeping time at the sintering temperature of about 1150℃ is longer, the compact shrinks considerably but on the contrary. the pore-structure becomes poor a little and the strength increases. Therefore, it is desirable sintering condition that the sintering temperature is about 1150℃ and keeping time is within 30 ~ 60min. As the results. compacting and sintering conditions of iron-tin sintered alloy can be detemined as follows. When tin powder having -350mesh of particle size is added about 1.0% into iron powder and compacted to about 22% of green porosity and then. sintered at 1150℃ for about 30min. the alloy will have following properties ; the dimensional change is about -0.2%, the intercommunicating porosity is about 20vol% and the radial crushing strength is about 30kgf/㎟ which are much better than the properties of the conventional sintered iron for porous bearing.