임플란트의 collar design이 변연골과 연조직에 미치는 영향

유현상,강선녀,정창모,윤미정,허중보,전영찬 대한치과보철학회 2012 대한치과보철학회지 Vol.50 No.1

연구 목적: 임플란트 경부가 잘 설계된 경우 양호한 연조직 반응을 통해 변연골을 보존하는데 도움이 된다. 본 실험에서는 연, 경조직 경계부에 가장 가까이 위치하는 임플란트의 collar design이 변연골 변화와 연조직 반응에 미치는 영향을 동물실험을 통해 알아보고자 하였다. 연구 재료 및 방법: 2마리의 건강한 Beagle dog에 임플란트 collar design만 다른 두 종류의 임플란트(Neobiotech Co. Seoul, Korea)를 식립하였다. Collar에 bevel 을 부여한 군(Bevel 군)과 "S"자 형태를 부여한 군(Bioseal 군)으로 나누어 마리 당 7개, 군당 7개, 총 14개의 임플란트를 무작위로 식립한 후 Healing abutment를 즉시 체결하였다. 디지털 표준구내 방사선사진을 이용해 4주 간격으로 총 12주간 근원심 변연골 변화를 관찰하였고, 12주에 희생하여 조직학적 분석을 통해 협설 변연골 흡수 및 임플란트 주변 연조직 반응을 평가하였다. Mann-Whitney test를 통해 동일한 방사선 사진 촬영 시점에서 근원심 변연골 변화량 및 조직계측치를 군 간 비교하였고, Kruskal-Wallis test를 통해 방사선 사진상 근원심 변연골 변화량이 시간에 따른 차이가 있는지 군 내 분석 한 후 Duncan test를 통해 사후 검증하였다(α=.05). 결과: 방사선학적 분석 결과 각 촬영 시점에서 두 군간 근원심 변연골 변화량의 차이를 보이지 않았다(P>.05). 군 내에서 시간에 따른 근원심 변연골의 흡수량을 분석한 결과 Bevel 군에서는 시간에 따른 차이를 보이지 않았으나 (P>.05), Bioseal 군에서는 시간에 따른 차이를 보였으며, 4주및8주와 비교했을 때 12주에서 변연골의 증가를 보였다(P<.05). 조직학적 분석 결과 협설측 변연골 흡수량에서 두 군간 차이를 보이지 않았으나 (P>.05), Bevel 군에 비해 Bioseal 군에서 더 견고한 결합조직부착을 관찰할 수 있었으며, 생물학적 폭경의 값은 두 집단 간 차이를 보이지 않은 반면에 (P>.05), 접합상피부착은 Bevel 군에서 유의하게 길었고, 결합조직부착은 Bioseal 군에서 더 길게 나타났다(P<.05). 결론: Bevel 군에 비해 Bioseal 군에서 결합조직부착은 길게 형성된 반면에 접합상피부착은 더 짧게 나타났으며, 생물학적 폭경과 초기 변연골 흡수에는 차이가 없음을 알 수 있었다. 연조직 반응의 차이가 실제 기능하중 하에서 변연골 변화에 미치는 영향에 대해서 향후 연구가 필요할 것으로 생각된다. PURPOSE. The purpose of this study was to investigate the effects of implant collar design on marginal bone change and soft tissue response by an animal test. MATERIALS AND METHODS. Two types of Implant (Neobiotech Co. Seoul, Korea) that only differs in collar design were planted on two healthy Beagle dogs. The implants were divided into two groups, the first group with a beveled collar (Bevel Group) and the second group with "S" shaped collar (Bioseal group). Standardized intraoral radiographs were used to investigate the mesio-distal change of the marginal bone. Histological analysis was done to evaluate the bucco-lingual marginal bone resorption and the soft tissue response adjacent to the implant. Mann-Whitney test was done to compare the mesio-distal marginal bone change at equivalent time for taking the radiographs and the tissue measurements between the groups. RESULTS. Radiographic and histological analysis showed that there was no difference in marginal bone change between the two groups (P>.05). Histological analysis showed Bioseal group had more rigid connective tissue attachment than the Bevel group. There was no difference in biological width (P>.05). Bevel group showed significantly longer junctional epithelium attachment and Bioseal group showed longer connective tissue attachment (P<.05). CONCLUSION. For three months there were no differences in marginal bone change between the Bevel group and the Bioseal group. As for the soft tissue adjacent to the implant, Bioseal group showed longer connective tissue attachment while showing shorter junctional epithelium attachment. There were no differences in biologic width.

한국어판 예일 틱 증상 평가척도 : 신뢰도 및 타당도 연구

정선주,이정섭,유태익,구영진,전성일,김봉석,홍강의 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.5

목 적 : 틱 증상의 심한 정도를 평가하기 위한 도구인 예일 틱 증상 평가척도(Yale Global Tic Severity Scale)를 한국판 가정 평가용 설문지 및 임상 평가용 척도로 개발하기 위하여 본 연구를 시행하였다. 방 법 : 예일 틱 증상 평가척도는 뚜렛 장애 및 기타 틱 장애에서 나타나는 운동틱과 음성틱 각각의 증상의 수, 빈도, 심한 정도, 복합성, 방해 정도 및 장해도를 포괄적으로 평가하도록 고안되어져 있다. 틱 증상을 주소로 정신과외래를 방문한 만 4.3세에서 19세까지의 100명의 환아 및 부모들을 대상으로 한국어로 번역한 예일 틱 증상 평가척도의 가정평가용 설문지를 평가전에 완료하도록 한 후, 면담을 통한 임상평가용 척도를 실시하였으며 수렴타당도 및 변별타당도의 검증을 위해 총괄적인 임상 인상척도-뚜렛 증후군, 강박장애, 주의력결립/과잉운동장애(Clinical Global Impression-TS, OCD, ADHD)를 시행하였다. 결 과 : 자료분석결과 내적일치도, 수렴타당도, 변별타당도 및 검사자간 신뢰도 모두 매우 높게 나타났으며 요인분석상 전 항목척도와 장해도는 운동틱과 음성틱에 해당하는 2개의 요인으로 묶여졌다. 결 론 : 본 연구결과 한국판 예일 틱 증상 평가척도의 높은 타당도 및 신뢰도가 입증되었으며 이는 향후 틱 증상의 객관적인 평가 및 정량화를 위해 유용하게 사용되어질 수 있을 것이다. Objectives : This study was carried out to develop the Korean form of Yale Global Tic Severity Scale(YGTSS)-family & clinical rating version. The severity of motor and phonic tics was rated according to five separate dimensions : number, frequency, intensity, complexity, and interference. Methods : The Korean form of YGTSS was applied to 100 children who visited psychiatric outpatient clinic with chief complaints of tic symptom. Together with YGTSS, Clinical Global Impression for Tourette's syndrome(CGI-TS), Obsessive-Compulsive disorder(CGI-OCD), Attention-Deficit/Hyperactivity Disorder(CGI-ADHD) were administered to all subjects for examining convergent and discriminant validities. Results : We could confirm high internal consistency, convergent and discriminant validities and interrater reliability of YGTSS by analysing data from 100 children with tic disorder. In factor analysis, items were clustered to 2 factors which were identical to motor and phonic tic subscales. Conclusion : The results of this study indicate the Korean form of YGSS is a reliable and valid rating scale for rating tic symptom severity. It can be used to evaluate tic symptom objectively and to quantify the tic severity in the studies for tic disorder.

Pathological Fracture of the Femoral Neck due to Tophaceous Gout: An Unusual Case of Gout

Yoo-Sun Jeon,황득수,황정모,Jeong-Kil Lee,박용철 대한고관절학회 2019 Hip and Pelvis Vol.31 No.4

A 48-year-old man visited the emergency room with right hip pain that started abruptly while walking out of the bathroom. Computed tomography showed an intraosseous mass in the femoral neck. The patient had a 15-year history of gout and had numerous bilateral tophi in his hands, feet, knees, and elbows. After operation, we diagnosed a pathological fracture due to intraosseous tophi. Patients with hip pain who have many subcutaneous tophi and long-standing gout should be diagnosed carefully. Peri-hip joint pain caused by gout is uncommon, however, if a patient complains of pain, a simple X-ray may be required. If intraosseous tophi are present, appropriate treatment (e.g., strict hyperuricemia control with or without prophylactic internal fixation), may be required before fracture occurs.

인공 고관절 전치환술 후 발생한 치환물 주위 종괴

전유선 ( Yoo Sun Jeon ),황득수 ( Deuk Soo Hwang ),강찬 ( Chan Kang ),김의창 ( Eui Chang Kim ),이기수 ( Gi Soo Lee ),송재황 ( Jae Whang Song ) 대한고관절학회 2012 Hip and Pelvis Vol.24 No.3

보육교사 휴게시간 운영에 대한 원장과 보육교사의 인식과 요구 비교

전필선(Jeon, Pil-Sun),전유영(Jeon, Yoo-Young) 한국열린유아교육학회 2021 열린유아교육연구 Vol.26 No.2

본 연구는 보육교사 휴게시간 운영에 대한 원장과 보육교사의 인식과 요구 차이를 알아보는 데 그 목적이 있다. 본 연구에서는 원장과 보육교사를 대상으로 설문조사를 실시하여 최종적으로 425부를 연구자료로 사용하였으며 수집된 자료는 독립표본 t-검정을 통해 분석되었다. 연구결과, 보육교사 휴게시간 의사결정과정의 적절성, 기획 및 편성의 적절성, 개선 노력의 적극성, 휴게시간 운영에 대한 기대효과, 휴게시간 운영에 대한 요구에서 원장과 보육교사의 인식은 통계적으로 유의미한 차이를 나타내었다. 보육교사 휴게시간 의사결정과정의 적절성, 기획 및 편성의 적절성, 개선 노력의 적극성에서 원장의 인식 수준이 보육교사보다 상대적으로 높게 나타났다. 반면, 휴게시간 운영에 대한 기대효과, 휴게시간 운영에 대한 요구는 원장보다 보육교사의 인식 수준이 상대적으로 높게 나타났다. 본 연구결과는 휴게시간 사용에 관한 원장과 보육교사의 합의점을 도출하고 실효성 있는 정책을 마련하는 데 기초자료로 활용되리라 기대한다. The purpose of this study was to examine the difference in perceptions and demands between directors and daycare teachers on the break time management. In this study, a questionnaire survey was conducted to directors and daycare teachers, and 425 copies were finally used as research data. The collected data were analyzed using an independent sample t-test. As a result of the study, there were statistically significant differences between the perceptions of the directors and the daycare teachers in the appropriateness of the break time decision-making process, the adequacy of planning and organization, active efforts for improvement, the expected effect on the break time management, and the demands for the break time management. The level of the perceptions of the directors was relatively higher than that of the daycare teachers in the appropriateness of the decision-making process for the daycare teachers, the appropriateness of planning and organization, and the active efforts to improve. On the other hand, the daycare teachers expressed the expected effects on the break time management and the demands for the break time management higher than that of the directors. The results of this study are expected to be used as basic data to draw an agreement between the directors and the daycare teachers on the use of recess hours and to establish effective policies.

고관절 전치환술 후 비구컵 고정 나사못 돌출에 의한 비구컵 라이너의 해리: 2예 보고

전유선 ( Yoo Sun Jeon ),황득수 ( Deuk Soo Hwang ),강찬 ( Chan Kang ),김필성 ( Pil Sung Kim ),황정모 ( Jung Mo Hwang ),송재황 ( Jae Hwang Song ) 대한고관절학회 2013 Hip and Pelvis Vol.25 No.3

무시멘트형 고관절 전치환술을 받은 환자들 중 비구 고정 나사못 이완에 의한 비구컵 라이너(acetabular liner)의 해리(dissociation) 소견을 보였던 2예의 보고이다. 두 예에서 환자는 수술 후 통증과 관절 잡음의 발생을 주소로 내원하였고 방사선학적 소견상 지주형태 골이식 부위의 붕괴(collapse) 소견을 보이며 비구컵 라이너가 해리된 소견을 보였다. 모든 예에서 재치환술 시 나사못이 비구컵 안쪽으로 돌출(extrusion)되어 있었고 비구컵이 상부로 이동되면서 이로 인하여 비구컵의 라이너가 해리된 것으로 추정되었다. 지금까지 고관절 전치환술 후 나사못의 관절내 돌출에 의한 비구컵 라이너 해리에 대한 증례는 보고되지 않았다. 이에 저자들은 구조성 자가골 이식(structural autogenous bone graft)을 시행한 고관절 전치환술 후 나사못 문제로 인하여 발생한 인공 관절 비구컵 라이너의 해리에 대한 증례보고를 하고자 한다. This is a report of 2 cases that showed dissociation of the acetabular cup liner by acetabular fixation screw among patients who underwent total hip replacement. Screws for fixation of the acetabular cup were used during the primary surgery in both cases. Each patient visited the out patient department complaining of pain and noise from the joint; radiologic finding revealed a collapse of the column shape bone graft area with dissociation of the acetabular cup liner. In both cases, during revision surgery, screw was extruded to the inner side of the acetabular cup, since it migrated superiorly. There has been no report of liner dissociation by extrusion of acetabular cup fixation screw after total hip replacement. Therefore, we report two cases of dissociation of the acetabular cup liner of hip arthroplasty, which occurred due to screw issues after total hip replacement with structural autogenous bone graft.

대퇴 비구 충돌과 동반된 비구순 파열의 관절경적 비구순 봉합술 -초기 2-5년 추시 결과-

전유선 ( Yoo Sun Jeon ),황득수 ( Deuk Soo Hwang ),강찬 ( Chan Kang ),황정모 ( Jung Mo Hwang ),이기수 ( Gi Soo Lee ) 대한고관절학회 2013 Hip and Pelvis Vol.25 No.2

목적: 대퇴 비구 충돌 및 비구순 파열로 진단받고 관절경적 비구순 봉합술을 시행한 환자들의 단기 추시 후 결과를 보고하고자 한다. 대상 및 방법: 2008년부터 2010년까지 대퇴 비구 충돌 및 비구순 파열로 진단받고 관절경적 비구순 봉합술을 시행한 45명을 대상으로 하였다. 임상 결과는 modified Harris hip score (MHHS), 통증 점수(VAS), hip outcomes score (HOS) 및 환자 만족도를 이용하였다. 결과: 남자 22명, 여자 23명이었고, 평균 나이는 33.0세(16-54세), 평균 추시 기간은 26.7개월(24-56개월)이었다. 임상적 결과로 VAS는 수술 전 평균 6.4점에서 수술 후 평균 2.5점, MHHS는 수술전 평균 59.5점에서 수술 후 평균 85.4점으로 호전되었고, HOS의 일상 생활척도와 운동 척도가 각각 수술 전 평균 58.3%, 51.2%, 수술 후 평균 83.0%, 79.8%이었다. 재수술을 시행한 경우는 5예(12.1%)로 비구순 부위의 활액막 증식에 의한 유착이 3예, 봉합 나사못이 빠진 경우가 1예, 이소성 골화가 1예 관찰되었다. 결론: 관절경적 비구순 봉합술은 대퇴 비구 충돌과 동반된 비구순 파열의 치료로 효과적인 방법으로 생각된다. Purpose: The purpose of this study is to report on the short term follow-up of patients who underwent arthroscopic acetabular labral repair for femoroacetabular impingement and acetabular labral tear.. Materials and Methods: A total of 45 consecutive patients who underwent arthroscopic acetabular labral repair after diagnosis of femoroacetabular impingement and acetabular labral tear from January 2008 to December 2010 were included in this study. Modified Harris hip score (MHHS), VAS, Hip outcomes score (HOS), and patient satisfaction were used for evaluation of the clinical results. Results: Patients included 22 males and 23 females, and the mean age of the patients was 33.0(range, 16-54) years old, and the mean follow up period was 26.7(range, 24-56) months. Of the clinical results, mean VAS score was 6.4 and 2.5 points before and after surgery, respectively, and mean MHHS score improved from 59.5 points before surgery to 85.4 points after surgery. Activities of daily living and sports-related activities of HOS were 58.3% and 51.2%, respectively, before surgery, and 83.0% and 79.8% after surgery. Revision arthroscopic surgery was performed on five cases(12.1%); labro-synovial adhesion, three cases, pull-out of suture anchor, one case, heterotropic ossification, one case. Conclusion: Arthroscopic acetabular labral repair is considered an effective treatment for femoroacetabular impingement and accompanying acetabular labral tear.

Effects of gut microbiota on the pharmacokinetics of protopanaxadiol ginsenosides Rd, Rg3, F2, and compound K in healthy volunteers treated orally with red ginseng

Jeon-Kyung Kim,Min Sun Choi,Woonhee Jeung,Jehyeon Ra,Hye Hyun Yoo,DONG-HYUNKIM 고려인삼학회 2020 Journal of Ginseng Research Vol.44 No.4

Background: It is well recognized that gut microbiota is involved in the biotransformation of ginsenosidesby converting the polar ginsenosides to nonpolar bioactive ginsenosides. However, the roles of thegut microbiota on the pharmacokinetics of ginsenosides in humans have not yet been fully elucidated. Methods: Red ginseng (RG) or fermented red ginseng was orally administered to 34 healthy Koreanvolunteers, and the serum concentrations of the ginsenosides were determined using liquidchromatographyetandem mass spectrometry. In addition, the fecal ginsenoside Rde and compound K(CK)eforming activities were measured. Then, the correlations between the pharmacokinetic profiles ofthe ginsenosides and the fecal ginsenosideemetabolizing activities were investigated. Results: For the RG group, the area under the serum concentrationetime curve values of ginsenosides Rd,F2, Rg3, and CK were 8.20 11.95 ng$h/mL, 4.54 3.70 ng$h/mL, 36.40 19.68 ng$h/mL, and40.30 29.83 ng$h/mL, respectively. For the fermented red ginseng group, the the area under curve fromzero to infinity (AUCN) values of ginsenosides Rd, F2, Rg3, and CK were 187.90 95.87 ng$h/mL,30.24 41.87 ng$h/mL, 28.68 14.27 ng$h/mL, and 137.01 96.16 ng$h/mL, respectively. The fecal CKformingactivities of the healthy volunteers were generally proportional to their ginsenoside Rdeformingactivities. The area under the serum concentrationetime curve value of CK exhibited an obvious positivecorrelation (r ¼ 0.566, p < 0.01) with the fecal CK-forming activity. Conclusion: The gut microbiota may play an important role in the bioavailability of the nonpolar RGginsenosides by affecting the biotransformation of the ginsenosides.

Comparison Between Contrast-Enhanced Computed Tomography and Contrast-Enhanced Magnetic Resonance Imaging With Magnetic Resonance Cholangiopancreatography for Resectability Assessment in Extrahepatic Cholangiocarcinoma

Yoo Jeongin,Lee Jeong Min,Kang Hyo-Jin,Bae Jae Seok,Jeon Sun Kyung,Yoon Jeong Hee 대한영상의학회 2023 Korean Journal of Radiology Vol.24 No.10

Objective: To compare the diagnostic performance and interobserver agreement between contrast-enhanced computed tomography (CECT) and contrast-enhanced magnetic resonance imaging (CE-MRI) with magnetic resonance cholangiopancreatography (MRCP) for evaluating the resectability in patients with extrahepatic cholangiocarcinoma (eCCA). Materials and Methods: This retrospective study included treatment-naïve patients with pathologically confirmed eCCA, who underwent both CECT and CE-MRI with MRCP using extracellular contrast media between January 2015 and December 2020. Among the 214 patients (146 males; mean age ± standard deviation, 68 ± 9 years) included, 121 (56.5%) had perihilar cholangiocarcinoma. R0 resection was achieved in 108 of the 153 (70.6%) patients who underwent curative-intent surgery. Four fellowship-trained radiologists independently reviewed the findings of both CECT and CE-MRI with MRCP to assess the local tumor extent and distant metastasis for determining resectability. The pooled area under the receiver operating characteristic curve (AUC), sensitivity, and specificity of CECT and CE-MRI with MRCP were compared using clinical, surgical, and pathological findings as reference standards. The interobserver agreement of resectability was evaluated using Fleiss kappa (κ). Results: No significant differences were observed between CECT and CE-MRI with MRCP in the pooled AUC (0.753 vs. 0.767), sensitivity (84.7% [366/432] vs. 90.3% [390/432]), and specificity (52.6% [223/424] vs. 51.4% [218/424]) (P > 0.05 for all). The AUC for determining resectability was higher when CECT and CE-MRI with MRCP were reviewed together than when CECT was reviewed alone in patients with discrepancies between the imaging modalities or with indeterminate resectability (0.798 [0.754–0.841] vs. 0.753 [0.697–0.808], P = 0.014). The interobserver agreement for overall resectability was fair for both CECT (κ = 0.323) and CE-MRI with MRCP (κ = 0.320), without a significant difference (P = 0.884). Conclusion: CECT and CE-MRI with MRCP showed no significant differences in the diagnostic performance and interobserver agreement in determining the resectability in patients with eCCA.

산전진찰에 영향을 주는 여러 요인의 분석

선우성,강재헌,전옥희,김창엽,황인홍,유태우,성낙진,허봉렬 대한가정의학회 1991 Korean Journal of Family Medicine Vol.12 No.9