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Evaluation of Skin color According to Relative Temperature
Yoo Na Cho,YungKyung Park 한국색채학회 2017 AIC 2017 Jeju Vol.2017 No.10
For domestic and foreign brands make-up products, which classifies color according to relative temperature have been launched. Temperature sense is one of the relatively consistent factors in color emotion. Therefore, research on color temperature has been continuously carried out. In the study, personal colors are mentioned when considering colors that match the skin color of an individual such as make-up; when separating color into temperature sense, we use a relative temperature sense rather than a general temperature sense. In this study, we learn about general temperature and relative temperature; and the effect of color classified by psychological temperature sensation on skin color was evaluated through two types of skin colors. 18 colors, which were classified into warm and cool colors according to relative temperature, were matched with two skin image samples. The two image samples were distinguished also by a comparison of a warm skin tone and a cold skin tone. As a result, among the evaluated factors, “harmonious” indicates the correlation between the “health” and “transparency” of the skin color. In addition, the cooler skin tone image was assessed as “health” and “transparency” when it matched cooler color samples. Therefore, it was assessed also as harmony. The other skin image, which is warmer, was assessed as “health” and “transparency” when it matched warmer color samples. Moreover, it was assessed also as harmony. When the same color of the relative temperature sense occurs, it is adjudged that the skin color is “healthy” and “transparent”, and it is evaluated that the match of the color is harmonious.
Protein C 결핍에서 발생한 소모성 응고질환으로 인한 뇌내출혈로 야기된 뇌성마비 환자에 대한 증례기록
조유나(Yoo na Cho),이영목(Young Mock Lee),박은숙(Eun Sook Park),최자영(Ja Young Choi),박천웅(Chun ung Park),나동욱(Dong wook Rha) 대한소아신경학회 2017 대한소아신경학회지 Vol.25 No.1
Protein C는 응고인자 Va와 VIIIa를 비활성시키는 항응고 인자로써 PROC 결핍은 매우 희귀한 질환으로 열성유전이 되며 다양한 혈전성 또는 허혈성 질환을 일으킬 수 있는 것으로 알려져 있다. 심한 경우에는 소모성 응고병증 상태를 야기시켜 사망에 이르게 할 수도 있다. 우리는 본 논문을 통하여 합성이질접합형(compound heterozy gous)으로 유전된 PROC 결핍 환자에서 소모성 응고병증으로 인한 출혈성 뇌졸중 환아 두 명을 기술하였고, 진단검사와 유전자검사, 뇌 자기공명영상 이미지와 기능적 상태를 함께 분석하였다. 또한 PROC 결핍 환자에서 발생할 수 있는 합병증 중 전격성 자반 피부병변을 소개하여 항응고인자 투약치료로 인하여 발생가능한 혈종과 구별이 필요함을 소개하고자 하였다. Protein C (PROC) is a potent anticoagulant inactivating coagulation factors Va and VIIIa. PROC deficiency is very rare condition inherited as an autosomal dominant or recessive trait, and associated with various thromboembolic and ischemic conditions. Moreover, severe form of PROC deficiency can cause fatal hemorrhagic complications due to consumptive coagulopathy. We reported two children with hemorrhagic stroke who were diagnosed as severe PROC deficiency caused by two different types of compound heterozygous PROC gene mutations. We described results of laboratory tests, genetic analysis, brain magnetic resonance images, and functional outcomes. Both children received prophylactic anticoagulation therapy and presented with purple-colored skin lesions during rehabilitation. Purpura fulminans caused by insufficient anticoagulation should be differentiated from hematoma caused by excessive anticoagulation therapy in these children.
( Jeong-ju Yoo ),( Su Jong Yu ),( Juri Na ),( Kyungmin Kim ),( Young Youn Cho ),( Hyeki Cho ),( Dong Hyeon Lee ),( Eun Ju Cho ),( Jeong-hoon Lee ),( Yoon Jun Kim ),( Chung Yong Kim ),( Hyewon Youn ),( 대한간학회 2016 춘·추계 학술대회 (KASL) Vol.2016 No.1
Aims: Enhancing sorafenib sensitivity is essential for achieving efficient control of intractable hepatocellular carcinoma (HCC). Considering that sorafenib exerts its effect by endoplasmic reticulum (ER) stress due to hypoxia and energy depletion through anti-angiogenic aspect, hexokinase (HK) II which is an important rate-limiting glycolytic enzyme can be a key player in countervailing the effect of sorafenib. Pyruvate analog 3-bromopyruvate (3-BP), a HK II inhibitor, can promote tumor cell death by augmenting endoplasmic reticulum (ER) stress in human HCC cell lines. We evaluated inhibition of HK II potentiated sorafenib-induced ER stress in HCC cells. We also postulated that simultaneous treatment with sorafenib and 3-BP might synergistically enhance their anti-tumor efficacies against HCCs in vivo models. Methods: HCC apoptotic cell death was assessed by DAPI staining and apoptotic signaling pathways were explored by immunoblot analysis. Energy depletion was assessed by lactate assay. In vivo ectopic model of HCC was established in BALB-c nu/nu mice intradermally implanted with SNU-761 cells. Moreover, orthotopic model of HCC was established by subcapsular injection of SNU-761 cells via mini-laparotomy in BALB-c nu/nu mice. Sorafenib with/without 3-BP was subsequently administered. The anti-tumor efficacies were
이정열 ( Jung Ryul Lee ),차진영 ( Jin Young Cha ),조헌영 ( Hun Young Cho ),이유경 ( Yoo Kyung Lee ),박민수 ( Min Soo Park ),이유석 ( Yoo Seok Lee ),나영정 ( Young Jeong Na ),조수현 ( Soo Hyun Cho ),조삼현 ( Sam Hyun Cho ),정성로 ( 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.12
목적 : 폐경 여성을 대상으로 4년간의 호르몬 대체요법이 골밀도에 미치는 여러 영향을 분석하고자 하였다. 특히 호르몬 대체요법에도 골밀도가 감소하는 여성들의 특성을 알아보고자 하였다. 연구 방법 : 4년간 호르몬 대체요법을 완료한 총 100명의 폐경 여성을 대상으로 하였다. 이중에너지방사선흡수계측기를 이용하여 매년 요추골밀도를 측정하였다. 결과 : 대상환자의 평균연령은 53.3±3.6세, 폐경연령은 4.7±4.0세이었다. 치료 전 골밀도에 따라 분류하면 Objective : To evaluate the various effects of hormone replacement therapy (HRT) on bone mineral density (BMD) for 4 years in postmenopausal women and to compare the characteristics of non-responders to HRT. Methods : A total of 100 postmenopausal women h
Ha, Jong-Hun,Lee, Dong-Hae,Park, Jin-Sik,Cho, Oh Hyun,Kim, Dong-Hoon,Ha, Na-Young,Cho, Nam-Hyuck,Hwang, Kyu Jam,Cho, Yong-Gon,Lee, Hye-Soo,Lee, Won Kil,Lee, Yoo Chul,Cho, Myung-Je,Lee, Woo-Kon,Shin, M The Korean Society for Microbiology 2016 Journal of Bacteriology and Virology Vol.46 No.4
Orientia tsutsugamushi (O. tsutsugamushi), which is endemic to an Asia-Pacific region, has increased its incidence and caused annually around 10 thousand patients infected with scrub typhus in Korea in the past several years. In the present study, we isolated 44 O. tsutsugamushi from the patients with febrile illness accompanied with or without an eschar in Gyeongsangnam-do, Korea. These isolates were characterized by genetic analysis of the major outer membrane protein, the 56-kDa type-specific antigen (tsa56), which is unique to O. tsutsugamushi. Two types of sequences of tsa56, designated by JJ1 and JJ2, were determined from 37 and 7 isolates of the 44 isolates, respectively. JJ1 and JJ2 showed 74.7~90.8% identity in nucleotide sequence and 66.1~90.5% identity in amino acid sequence with 33 reference strains except for Boryong and Kuroki. JJ1 and JJ2 had 100 and 99.9% nucleotide identity to Boryong strain, and 99.9 and 99.8 % to Kuroki, which has been known to be similar to Boryong, respectively. In addition, they showed 77.9~ 81.4% nucleotide identity with the cluster of Gilliam-related genotypes, whereas they showed higher nucleotide identity (89.6~90.8%) with the cluster of Karp-related genotypes. To our knowledge, this is the first report to isolate O. tsutsugamushi and characterize their genotype as the Boryong in Jinju and West Gyeongsangnam-do, Korea, even though it has been reported that the Boryong was the predominant genotype in isolates from chiggers, domestic rodents, and patients in the southern part of Korea. Furthermore, our isolates could be useful source to study on the pathophysiology and epidemiology of scrub typhus in Korea.