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삼첨판 기계식 인공판막 대치술을 포함한 세 차례 개심술을 시행한 환자에서 대심정맥을 통한 영구 박동조율기 이식 1예 보고
김재욱,이진호,최주원,김우식,김용인 인제대학교 백병원 2003 仁濟醫學 Vol.24 No.2
A 26-year-old man. who had undergone three times open heart surgeries including tricuspid mechanical valve replacement 4 months before, with general weakness and mild dyspnea was admitted. He presented a third degree atrioventricular block on the electrocardiogram and required permanent pacemaker implant. We successfully implanted a permanent pacemaker transvenously with a ventricular lead introduced into the great cardiac vein via coronary sinus to stimulate the left ventricle, an atrial lead in the right atrium, and his symptoms improved.
쑥갓의 생리활성 연구(Ⅱ)-STZ에 유도된 흰쥐에서의 과산화지질 생성계에 미치는 영향
정운용,천현욱,최종원,이용범,황기욱 慶星大學校 環境問題硏究所 1998 環境硏報 Vol.8 No.1
Chrysanthemum coronarium L. has long been used the appetite and constipation in oriental countries. We was investigated the effect on changes in serum and hepatic free radical generatin enzymes and free radical scavenging enzymes as well as detoxification mechanism of each fraction from Chrysanthemum coronarium by examining the induction of streptozotocin.(STZ) Male Sprague-Dawley rats(190∼210g), with free access to commercial rat chow (Cheil Foods & Chemical Inc.) and water, were divided into six groups : Group 1 served as normal; Group 4 received ethyl acetate fraction in STZ animal; Group 5 received butanol fraction in STZ animal; Group 6 received water fraction in STZ-induced rat. In the STZ-induced diabetic group, the serum superoxide dismutase activity decreased and formation of hydroxyl radical increased when dompared to normal. STZ caused increase hepatic lipid peroxide content was inhibited by treatment with Chrysanthemum coronarium butanol fraction and STZ decreased the hepatic glutathione compared to normal, but this was inhibited Chrysanthemum coronarium butanol fraction treatment.STZ induced change in hepatic microsomal cytochrome P-450 activity was inhibited by treatment with Chrysanthemum coronarium butanol fraction. STZ caused a significant rise in hepatic aniline hydroxylase and xanthine oxidase, decrease in aminopyrine N-demethylase when compared to normal. Activities of hepatic superoxide dismutase, catalase and glutathione peroxidase were significant rised by treatment with Chrysanthemum coronarium butanol fraction when compated to STZ. These results suggest that Chrysanthemum coronarium butanol fraction treatment suppressed STZ induced changes in serum and hepatic metabolizing enzymes system.
Lee Yong Min,Son Dong Wuk,Oh Bu Kwang,Lee Su Hung,Lee Jun Seok,Kim Young Ha,Sung Soon Ki,Lee Sang Weon,Song Geun Sung 대한말초신경학회 2023 The Nerve Vol.9 No.2
Objective: As Korea has become a super-aging society, the number of elderly patients with degenerative spinal disease has steadily increased. This study aimed to evaluate the usefulness of oblique lumbar interbody fusion (OLIF) by comparing the results and complications between OLIF and open spinal fusion in elderly patients with degenerative spinal disease.Methods: Thirty-one patients underwent one-level posterior lumbar interbody fusion (PLIF), and 35 patients underwent one-level indirect decompression OLIF. The clinical outcomes of the two patient groups were analyzed using the visual analog scale (VAS) and Oswestry Disability Index (ODI). Through a comparative analysis of pre- and post-operative images, we measured changes in disc height (DH) and foraminal height (FH), and investigated the occurrence of subsidence in each patient group. The cross-sectional area was measured using magnetic resonance imaging pre- and post-operatively in OLIF.Results: The pre-operative VAS and ODI scores were similar between the two groups and tended to improve post-operatively. In the OLIF group, the estimated blood loss (EBL) was significantly lower, DH and FH gains were more frequent, DH and FH maintenance was better, and cage subsidence occurred less frequently. In OLIF, psoas paresis and approach-site hematoma occurred; however, all patients with psoas paresis recovered without further treatment before discharge. In the PLIF group, dural tears occurred in four patients who recovered without revision surgery. Conclusion: OLIF enables indirect decompression, reduced EBL, shorter hospitalization, and lesser subsidence. OLIF is considered a beneficial, minimally invasive surgical method for elderly patients.
Lee Yong Min,이치형,Kim Chang Hyeun,Kim Young Ha,Sung Soon Ki,Son Dong Wuk,Lee Sang Weon,Song Geun Sung 대한말초신경학회 2023 The Nerve Vol.9 No.2
Hypertrophic pachymeningitis (HP) is a rare type of inflammatory fibrosis characterized by diffuse thickening of the dura mater, which may cause a compressive effect or vascular compromise. Progressively worsening headache is the usual symptom, along with ataxia and various cranial nerve palsies. This article describes a rare case of HP after burr hole trephination for a chronic subdural hemorrhage (CSDH). A 64-year-old man was admitted to the emergency room with a headache that had started approximately 2 weeks prior. After the diagnosis of CSDH on imaging, burr hole trephination was performed. Six months later, the patient visited the hospital again with a headache. He was diagnosed with a recurrence of CSDH, and a craniotomy was performed. A solid subdural granuloma was suspected and a pathological examination revealed acute and chronic inflammation. Tissue biopsy and laboratory blood tests did not reveal any abnormalities. Three months later, he visited the hospital again with a severe headache. Magnetic resonance imaging showed no significant difference in the area of the previous operation; however, focal venous congestion and localized venous ischemic or inflammatory changes were observed in the tentorium. A craniotomy was performed for biopsy, and the dura mater was very thick. The pathology was diagnosed as HP. After taking steroids and immunosuppressive agents, the patient's symptoms improved. HP is a rare chronic inflammatory condition of the dura mater that causes neurological deficits. If the diagnosis is not definitively established based on an imaging examination, it should be made through a surgical biopsy. Steroid and immunosuppressive agents can improve the prognosis after diagnosis.
LBS 기반 교통정보 수집 및 제공시스템 개발 - 데이터 연계/통합을 중심으로 -
기용걸 ( Yong-kul Ki ),안계형 ( Gye-hyeong Ahn ),김은정 ( Eun-jeong Kim ),최진욱 ( Jin-wuk Choi ),배광수 ( Kwang-soo Bae ),안용주 ( Yong-ju An ),강석이 ( Suk-lee Kang ),이기봉 ( Ki-bong Lee ),허재영 ( Jae-young Heo ) 한국정보처리학회 2008 한국정보처리학회 학술대회논문집 Vol.15 No.1
전국의 주요 도로에 센서를 설치하여 교통정보를 수집하고 가공하여, 사용자인 일반 국민, TSP, 공공 기관들에게 양질의 교통정보를 제공하기 위한 교통정보 수집/제공시스템의 데이터 연계/통합 모델을 제안하였다. 제안된 모델은 기존에 구축되어 있는 교통정보센터를 연계/통합하기 위하여 향상된 EAI 기술과 교통정보 교환기술 표준을 적용하여 서버간의 효율적인 통신을 가능하게 해준다.
( Kyou Chae Lee ),( Soo Yuhl Chae ),( Hyun Wuk Cha ),( Yong Hyun Jang ),( Weon Ju Lee ),( Do Won Kim ),( Seok Jong Lee ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2
Background: Studies for prognostic factor of malignant melanoma (MM) were well performed in the west due to relatively high incidence rate. However, there are little data of MM, available in Korea. Objectives: To investigate the current status of clinicopathological features and prognostic predictors of MM. Methods: One hundred sixty patients diagnosed with MM at our hospital from 2007 to 2013 were enrolled. We analyzed age, sex, tumor location, duration, thickness, ulceration, tumor-infiltrating lymphocytes (TIL), microscopic satellite (Ms), angiolymphatic invasion, mitosis, clinicopathologic subtype, and clinical stage by review of medical records and histopathological slides. Univariate analysis and multivariate analyses for survival were performed by means of the Cox proportional hazard model. Results: The ratio of female to male was 1.22 to 1 and the mean age was 60.6 years. Most of the tumors were located on the hands and feet. Acral lentiginous melanoma was the most common (69.6%), followed by nodular melanoma (12.8%), superficial spreading melanoma (12.8%), and lentigo maligna melanoma/lentigo maligna (4.7%). The poor prognosis was related to sex, Ms, mitosis, and stage by univariate analysis, whereas it was related to sex and Ms by multivariate analysis. Conclusion: Our study showed the clinicopathological features and prognostic factor of MM in Korea. But further study is needed because our study has limitation result from loss to follow-up in confirmed death.
( Kyou Chae Lee ),( Sang Lim Kim ),( Hyun Wuk Cha ),( Yong Hyun Jang ),( Weon Ju Lee ),( Do Won Kim ),( Seok Jong Lee ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2
Background: Incidence of cutaneous malignant tumor is increasing recently and the changes in pattern may be suggested. Nevertheless, there has been little research into the distribution, incidence of cutaneous malignant tumors in Daegu and Kyungpook Province. Objectives: To analyze changes of during recent two decade in incidence, clinical patterns of cutaneous malignant tumors in Kyungpook national university hospital(KNUH). Methods: We reviewed 1,527 cases of cutaneous malignant tumors from 1994 to 2013 at the Department of Dermatology in KNUH. We also devided subgroup into first (1994-2003) and second decade (2004-2014) to see changed over the years. Results: The average incidence of cutaneous malignant tumors among the total number of outpatients was 1.57% through whole study period. The incidence of cutaneous malignant tumors in the first half of the study period was 0.37% and in the second half was 2.05%. The highest average incidence was basal cell carcinoma (BCC) (first vs. second decade: 0.15% vs. 0.66%), followed by squamous cell carcinoma (SCC) (0.11% vs. 0.49%) and malignant melanoma (MM) (0.05% vs. 0.23). The most common site was the face in each decade. The overall recurrence was diagnosed in 55 of the 1,527 patients (3.60%). In each disease, the recurrence rate was 1.79% vs. 0.58% (BCC), 4.17% vs. 0.81% (SCC), and 0.60% vs. 1.47% (MM). Conclusion: This epidemiological study provided useful information for the distribution, incidence and prognosis of skin tumors.
최근 20년간 대구-경북 지역 피부악성종양에 관한 임상적 특징에 관한 고찰: 전반기 10년(1994∼2003)과 후반기 10년(2004∼2013)간 비교
이규채 ( Kyouchae Lee ),김민지 ( Min Ji Kim ),채수열 ( Soo Yuhl Chae ),차현욱 ( Hyun Wuk Cha ),장용현 ( Yong Hyun Jang ),이원주 ( Weon Ju Lee ),김도원 ( Do Won Kim ),이석종 ( Seok Jong Lee ) 대한피부과학회 2015 대한피부과학회지 Vol.53 No.7
Background: Although skin cancer incidence has recently increased, there has been little research into the incidence, clinical manifestations, and prognosis of skin cancers in Korea, especially in Daegu City and the Kyungpook Province. Objective: To analyze changes over the recent two decades in incidence and clinical patterns, including recurrence of skin cancers diagnosed at a university hospital in Daegu City. Methods: We reviewed 1,566 skin cancer cases from 1994 to 2013 at the Department of Dermatology in Kyungpook National University Hospital (KNUH). We also divided them into first (1994∼2003) and second group (2004∼2013) to examine changes over the years. Results: The average incidence of skin cancers among the total number of outpatients was 1.39% through whole study period including 0.38% in the first and 2.10% in the second decade. Basal cell carcinoma (BCC) was the most commonly diagnosed skin cancer (total:1st:2nd=0.60%:0.16%:0.91%), followed by squamous cell carcinoma (SCC) (0.43%:0.12%:0.65%) and malignant melanoma (MM) (0.22%:0.05%:0.34%). The most common skin cancer site was the face in each decade. The recurrence of three major skin cancers (BCC, SCC and MM) was diagnosed in 49 of the 1,402 patients (3.50%). In each disease, the recurrence rate (1st:2nd) was 1.64% (BCC, 4.11%:1.34%), 3.51% (SCC, 11.11%:2.55%), and 8.57% (MM, 4.35%:9.01%). Conclusion: This epidemiological study provided useful information about the incidence and prognosis of skin tumors in Korea, especially in Daegu City and Kyungpook Province. (Korean J Dermatol 2015;53(7):505∼514)